메뉴 건너뛰기




Volumn 50, Issue 7-8, 2007, Pages 883-889

Upregulation of cerebral cortical glutathione synthesis by ammonia in vivo and in cultured glial cells: The role of cystine uptake

Author keywords

Ammonia; Astrocytes; Brain; Cerebral cortex; Cystine uptake; Glutathione; Microdialysis; Striatum

Indexed keywords

AMMONIA; CYSTINE; GLUTATHIONE;

EID: 34250728449     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2006.12.003     Document Type: Article
Times cited : (26)

References (46)
  • 1
    • 0022638764 scopus 로고
    • Role of membrane transport in metabolism and function of glutathione in mammals
    • Bannai S., and Tateishi N. Role of membrane transport in metabolism and function of glutathione in mammals. J. Membr. Biol. 89 (1986) 1-8
    • (1986) J. Membr. Biol. , vol.89 , pp. 1-8
    • Bannai, S.1    Tateishi, N.2
  • 2
    • 0029877408 scopus 로고    scopus 로고
    • Effects of ammonia on l-glutamate uptake in cultured astrocytes
    • Bender A.S., and Norenberg M.D. Effects of ammonia on l-glutamate uptake in cultured astrocytes. Neurochem. Res. 21 (1996) 567-573
    • (1996) Neurochem. Res. , vol.21 , pp. 567-573
    • Bender, A.S.1    Norenberg, M.D.2
  • 3
    • 0033982710 scopus 로고    scopus 로고
    • Effect of ammonia on GABA uptake and release in cultured astrocytes
    • Bender A.S., and Norenberg M.D. Effect of ammonia on GABA uptake and release in cultured astrocytes. Neurochem. Int. 36 (2000) 389-395
    • (2000) Neurochem. Int. , vol.36 , pp. 389-395
    • Bender, A.S.1    Norenberg, M.D.2
  • 4
    • 0034256935 scopus 로고    scopus 로고
    • Characterization of cystine uptake in cultured astrocytes
    • Bender A.S., Reichelt W., and Norenberg M.D. Characterization of cystine uptake in cultured astrocytes. Neurochem. Int. 37 (2000) 269-276
    • (2000) Neurochem. Int. , vol.37 , pp. 269-276
    • Bender, A.S.1    Reichelt, W.2    Norenberg, M.D.3
  • 5
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72 (1976) 248-254
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 6
    • 0034257046 scopus 로고    scopus 로고
    • Effects of ammonia on glutamate transporter (GLAST) protein and mRNA in cultured rat cortical astrocytes
    • Chan H., Hazell A.S., Desjardins P., and Butterworth R.F. Effects of ammonia on glutamate transporter (GLAST) protein and mRNA in cultured rat cortical astrocytes. Neurochem. Int. 37 (2000) 243-248
    • (2000) Neurochem. Int. , vol.37 , pp. 243-248
    • Chan, H.1    Hazell, A.S.2    Desjardins, P.3    Butterworth, R.F.4
  • 7
    • 0026694525 scopus 로고
    • Glutathione in Parkinson's disease: a link between oxidative stress and mitochondrial damage?
    • Di Monte D.A., Chan P., and Sandy M.S. Glutathione in Parkinson's disease: a link between oxidative stress and mitochondrial damage?. Ann. Neurol. 32 (1992) S111-S115
    • (1992) Ann. Neurol. , vol.32
    • Di Monte, D.A.1    Chan, P.2    Sandy, M.S.3
  • 8
    • 0029921679 scopus 로고    scopus 로고
    • +-dependent glutamate transport activity in synaptosomes, C6 glioma, and Xenopus oocytes expressing excitatory amino acid carrier 1 (EAAC1)
    • +-dependent glutamate transport activity in synaptosomes, C6 glioma, and Xenopus oocytes expressing excitatory amino acid carrier 1 (EAAC1). Mol. Pharmacol. 49 (1996) 465-473
    • (1996) Mol. Pharmacol. , vol.49 , pp. 465-473
    • Dowd, L.A.1    Coyle, A.J.2    Rothstein, J.D.3    Pritchett, D.B.4    Robinson, M.B.5
  • 9
    • 0031788839 scopus 로고    scopus 로고
    • Glutathione restoration as indicator for cellular metabolism of astroglial cells
    • Dringen R., and Hamprecht B. Glutathione restoration as indicator for cellular metabolism of astroglial cells. Dev. Neurosci. 20 (1998) 401-407
    • (1998) Dev. Neurosci. , vol.20 , pp. 401-407
    • Dringen, R.1    Hamprecht, B.2
  • 10
    • 0033555806 scopus 로고    scopus 로고
    • Synthesis of the antioxidant glutathione in neurons: supply by astrocytes of CysGly as precursor for neuronal glutathione
    • Dringen R., Pfeiffer B., and Hamprecht B. Synthesis of the antioxidant glutathione in neurons: supply by astrocytes of CysGly as precursor for neuronal glutathione. J. Neurosci. 19 (1999) 562-569
    • (1999) J. Neurosci. , vol.19 , pp. 562-569
    • Dringen, R.1    Pfeiffer, B.2    Hamprecht, B.3
  • 11
    • 1242337480 scopus 로고    scopus 로고
    • Antioxidant defence of the neonatal rat brain against acute hyperammonemia
    • Garcia M.V., Lopez-Mediavilla C., de la Pena M.C.J., and Medina J.M. Antioxidant defence of the neonatal rat brain against acute hyperammonemia. Brain Res. 1001 (2004) 159-163
    • (2004) Brain Res. , vol.1001 , pp. 159-163
    • Garcia, M.V.1    Lopez-Mediavilla, C.2    de la Pena, M.C.J.3    Medina, J.M.4
  • 13
    • 0033993867 scopus 로고    scopus 로고
    • Activation of N-methyl-d-aspartate receptors in rat brain in vivo following acute ammonia intoxication: characterization by in vivo brain microdialysis
    • Hermenegildo C., Monfort P., and Felipo V. Activation of N-methyl-d-aspartate receptors in rat brain in vivo following acute ammonia intoxication: characterization by in vivo brain microdialysis. Hepatology 31 (2000) 709-715
    • (2000) Hepatology , vol.31 , pp. 709-715
    • Hermenegildo, C.1    Monfort, P.2    Felipo, V.3
  • 15
    • 0038066410 scopus 로고    scopus 로고
    • Taurine reduces ammonia- and N-methyl-d-aspartate-induced accumulation of cyclic GMP and hydroxyl radicals in microdialysates of the rat striatum
    • Hilgier W., Anderzhanova E., Oja S.S., Saransaari P., and Albrecht J. Taurine reduces ammonia- and N-methyl-d-aspartate-induced accumulation of cyclic GMP and hydroxyl radicals in microdialysates of the rat striatum. Eur. J. Pharmacol. 468 (2003) 21-25
    • (2003) Eur. J. Pharmacol. , vol.468 , pp. 21-25
    • Hilgier, W.1    Anderzhanova, E.2    Oja, S.S.3    Saransaari, P.4    Albrecht, J.5
  • 16
    • 0032973861 scopus 로고    scopus 로고
    • Glial cells protect neurons against oxidative stress via transcriptional up-regulation of the glutathione synthesis
    • Iwata-Ichikawa E., Kondo Y., Miyazaki I., Asanuma M., and Ogawa N. Glial cells protect neurons against oxidative stress via transcriptional up-regulation of the glutathione synthesis. J. Neurochem. 72 (1999) 2334-2344
    • (1999) J. Neurochem. , vol.72 , pp. 2334-2344
    • Iwata-Ichikawa, E.1    Kondo, Y.2    Miyazaki, I.3    Asanuma, M.4    Ogawa, N.5
  • 17
    • 0026637624 scopus 로고
    • A mechanism for glutamate toxicity in the C6 glioma cells involving inhibition of cystine uptake leading to glutathione depletion
    • Kato S., Negishi K., Mawatari K., and Kuo C.H. A mechanism for glutamate toxicity in the C6 glioma cells involving inhibition of cystine uptake leading to glutathione depletion. Neuroscience 48 (1992) 903-914
    • (1992) Neuroscience , vol.48 , pp. 903-914
    • Kato, S.1    Negishi, K.2    Mawatari, K.3    Kuo, C.H.4
  • 18
    • 20544457990 scopus 로고    scopus 로고
    • Mechanisms of ammonia-induced cell death in rat cortical neurons: roles of NMDA receptors and glutathione
    • Klejman A., We{ogonek}grzynowicz M., Szatmari E.M., Mioduszewska B., Hetman M., and Albrecht J. Mechanisms of ammonia-induced cell death in rat cortical neurons: roles of NMDA receptors and glutathione. Neurochem. Int. 47 (2005) 51-57
    • (2005) Neurochem. Int. , vol.47 , pp. 51-57
    • Klejman, A.1    Wegrzynowicz, M.2    Szatmari, E.M.3    Mioduszewska, B.4    Hetman, M.5    Albrecht, J.6
  • 19
    • 0141686953 scopus 로고    scopus 로고
    • Sources of oxygen radicals in brain in acute ammonia intoxication in vivo
    • Kosenko E., Venediktova N., Kaminsky Y., Montoliu C., and Felipo V. Sources of oxygen radicals in brain in acute ammonia intoxication in vivo. Brain Res. 981 (2003) 193-200
    • (2003) Brain Res. , vol.981 , pp. 193-200
    • Kosenko, E.1    Venediktova, N.2    Kaminsky, Y.3    Montoliu, C.4    Felipo, V.5
  • 20
    • 11344253878 scopus 로고    scopus 로고
    • Developmental expression of glutamate transporters and glutamate dehydrogenase in astrocytes of the postnatal rat hippocampus
    • Kugler P., and Schleyer V. Developmental expression of glutamate transporters and glutamate dehydrogenase in astrocytes of the postnatal rat hippocampus. Hippocampus 14 (2004) 975-985
    • (2004) Hippocampus , vol.14 , pp. 975-985
    • Kugler, P.1    Schleyer, V.2
  • 23
    • 0029904205 scopus 로고    scopus 로고
    • Reactive oxygen species involved in the glutamate toxicity of C6 glioma cells via xc antiporter system
    • Mawatari K., Yasui Y., Sugitani K., Takadera T., and Kato S. Reactive oxygen species involved in the glutamate toxicity of C6 glioma cells via xc antiporter system. Neuroscience 73 (1996) 201-208
    • (1996) Neuroscience , vol.73 , pp. 201-208
    • Mawatari, K.1    Yasui, Y.2    Sugitani, K.3    Takadera, T.4    Kato, S.5
  • 24
    • 0036640537 scopus 로고    scopus 로고
    • Cerebral cystine uptake: a tale of two transporters
    • McBean G.J. Cerebral cystine uptake: a tale of two transporters. Trends Pharmacol. Sci. 23 (2002) 299-302
    • (2002) Trends Pharmacol. Sci. , vol.23 , pp. 299-302
    • McBean, G.J.1
  • 25
    • 0032169935 scopus 로고    scopus 로고
    • Mitochondrial impairment as an early event in the process of apoptosis induced by glutathione depletion in neuronal cells: relevance to Parkinson's disease
    • Merad-Boudia M., Nicole A., Santiard-Baron D., Saille C., and Ceballos-Picot I. Mitochondrial impairment as an early event in the process of apoptosis induced by glutathione depletion in neuronal cells: relevance to Parkinson's disease. Biochem. Pharmacol. 56 (1998) 645-655
    • (1998) Biochem. Pharmacol. , vol.56 , pp. 645-655
    • Merad-Boudia, M.1    Nicole, A.2    Santiard-Baron, D.3    Saille, C.4    Ceballos-Picot, I.5
  • 26
    • 0034257048 scopus 로고    scopus 로고
    • Elevation of glutathione levels by ammonium ions in primary cultures of rat astrocytes
    • Murthy C.R., Bender A.S., Dombro R., Bai G., and Norenberg M.D. Elevation of glutathione levels by ammonium ions in primary cultures of rat astrocytes. Neurochem. Int. 37 (2000) 255-268
    • (2000) Neurochem. Int. , vol.37 , pp. 255-268
    • Murthy, C.R.1    Bender, A.S.2    Dombro, R.3    Bai, G.4    Norenberg, M.D.5
  • 27
    • 0035888288 scopus 로고    scopus 로고
    • Ammonia-induced production of free radicals in primary cultures of rat astrocytes
    • Murthy C.R., Rao K.V.R., Bai G., and Norenberg M.D. Ammonia-induced production of free radicals in primary cultures of rat astrocytes. J. Neurosci. Res. 66 (2001) 282-288
    • (2001) J. Neurosci. Res. , vol.66 , pp. 282-288
    • Murthy, C.R.1    Rao, K.V.R.2    Bai, G.3    Norenberg, M.D.4
  • 28
    • 0024322509 scopus 로고
    • Glutathione measurement by high-performance liquid chromatography separation and fluorometric detection of the glutathione-orthophthalaldehyde adduct
    • Neuschwander-Tetri B.A., and Roll F.J. Glutathione measurement by high-performance liquid chromatography separation and fluorometric detection of the glutathione-orthophthalaldehyde adduct. Anal. Biochem. 179 (1989) 236-241
    • (1989) Anal. Biochem. , vol.179 , pp. 236-241
    • Neuschwander-Tetri, B.A.1    Roll, F.J.2
  • 29
    • 0031238547 scopus 로고    scopus 로고
    • The glial glutamate transporter in hyperammonemia and hepatic encephalopathy: relation to energy metabolism and glutamatergic neurotransmission
    • Norenberg M.D., Huo Z., Neary J.T., and Roig-Cantesano A. The glial glutamate transporter in hyperammonemia and hepatic encephalopathy: relation to energy metabolism and glutamatergic neurotransmission. Glia 21 (1997) 124-133
    • (1997) Glia , vol.21 , pp. 124-133
    • Norenberg, M.D.1    Huo, Z.2    Neary, J.T.3    Roig-Cantesano, A.4
  • 31
    • 0020308323 scopus 로고
    • Parkinson's disease: a disorder due to nigral glutathione deficiency?
    • Perry T.L., Godin D.V., and Hansen S. Parkinson's disease: a disorder due to nigral glutathione deficiency?. Neurosci. Lett. 33 (1982) 305-310
    • (1982) Neurosci. Lett. , vol.33 , pp. 305-310
    • Perry, T.L.1    Godin, D.V.2    Hansen, S.3
  • 32
    • 0025941476 scopus 로고
    • The presence of glutathione in primary neuronal and astroglial cultures from rat cerebral cortex and brain stem
    • Pileblad E., Eriksson P.S., and Hansson E. The presence of glutathione in primary neuronal and astroglial cultures from rat cerebral cortex and brain stem. J. Neural Transm. Gen. Sect. 86 (1991) 43-49
    • (1991) J. Neural Transm. Gen. Sect. , vol.86 , pp. 43-49
    • Pileblad, E.1    Eriksson, P.S.2    Hansson, E.3
  • 33
    • 0344549778 scopus 로고    scopus 로고
    • Suppression of ammonia-induced astrocyte swelling by cyclosporin A
    • Rao K.V.R., Chen M., Simard J.M., and Norenberg M.D. Suppression of ammonia-induced astrocyte swelling by cyclosporin A. J. Neurosci. Res. 15 (2003) 891-897
    • (2003) J. Neurosci. Res. , vol.15 , pp. 891-897
    • Rao, K.V.R.1    Chen, M.2    Simard, J.M.3    Norenberg, M.D.4
  • 34
    • 20544437331 scopus 로고    scopus 로고
    • Role of oxidative stress in the ammonia-induced mitochondrial permeability transition in cultured astrocytes
    • Rao K.V.R., Jayakumar A.R., and Norenberg M.D. Role of oxidative stress in the ammonia-induced mitochondrial permeability transition in cultured astrocytes. Neurochem. Int. 47 (2005) 31-38
    • (2005) Neurochem. Int. , vol.47 , pp. 31-38
    • Rao, K.V.R.1    Jayakumar, A.R.2    Norenberg, M.D.3
  • 35
    • 0024324666 scopus 로고
    • Glutathione is present in high concentrations in cultured astrocytes but not in cultured neurons.
    • Raps S.P., Lai J.C., Hertz L., and Cooper A.J. Glutathione is present in high concentrations in cultured astrocytes but not in cultured neurons. Brain Res. 493 (1989) 398-401
    • (1989) Brain Res. , vol.493 , pp. 398-401
    • Raps, S.P.1    Lai, J.C.2    Hertz, L.3    Cooper, A.J.4
  • 36
    • 0027489346 scopus 로고
    • Cystine uptake and glutathione level in fetal brain cells in primary culture and in suspension
    • Sagara J., Miura K., and Bannai S. Cystine uptake and glutathione level in fetal brain cells in primary culture and in suspension. J. Neurochem. 61 (1993) 1667-1671
    • (1993) J. Neurochem. , vol.61 , pp. 1667-1671
    • Sagara, J.1    Miura, K.2    Bannai, S.3
  • 37
    • 0027421350 scopus 로고
    • Maintenance of neuronal glutathione by glial cells
    • Sagara J., Miura K., and Bannai S. Maintenance of neuronal glutathione by glial cells. J. Neurochem. 61 (1993) 1672-1676
    • (1993) J. Neurochem. , vol.61 , pp. 1672-1676
    • Sagara, J.1    Miura, K.2    Bannai, S.3
  • 39
    • 0026583030 scopus 로고
    • Effect of ammonium ions on synaptic transmission in the mammalian central nervous system
    • Szerb J.C., and Butterworth R.F. Effect of ammonium ions on synaptic transmission in the mammalian central nervous system. Prog. Neurobiol. 39 (1992) 135-153
    • (1992) Prog. Neurobiol. , vol.39 , pp. 135-153
    • Szerb, J.C.1    Butterworth, R.F.2
  • 40
    • 13544270851 scopus 로고    scopus 로고
    • Effect of glutamine synthetase inhibition on astrocyte swelling and altered astroglial protein expression during hyperammonemia in rats
    • Tanigami H., Rebel A., Martin L.J., Chen T.Y., Brusilow S.W., Traystman R.J., and Koehler R.C. Effect of glutamine synthetase inhibition on astrocyte swelling and altered astroglial protein expression during hyperammonemia in rats. Neuroscience 131 (2005) 437-449
    • (2005) Neuroscience , vol.131 , pp. 437-449
    • Tanigami, H.1    Rebel, A.2    Martin, L.J.3    Chen, T.Y.4    Brusilow, S.W.5    Traystman, R.J.6    Koehler, R.C.7
  • 43
    • 0001412747 scopus 로고    scopus 로고
    • Astrocytes provide cysteine to neurons by releasing glutathione
    • Wang X.F., and Cynader M.S. Astrocytes provide cysteine to neurons by releasing glutathione. J. Neurochem. 74 (2000) 1434-1442
    • (2000) J. Neurochem. , vol.74 , pp. 1434-1442
    • Wang, X.F.1    Cynader, M.S.2
  • 46
    • 0036129038 scopus 로고    scopus 로고
    • Ammonia-induced extracellular accumulation of taurine in the rat striatum in vivo: role of ionotropic glutamate receptors
    • Zielińska M., Hilgier W., Borkowska H.D., Oja S.S., Saransaari P., Goryński P., and Albrecht J. Ammonia-induced extracellular accumulation of taurine in the rat striatum in vivo: role of ionotropic glutamate receptors. Neurochem. Res. 27 (2002) 37-42
    • (2002) Neurochem. Res. , vol.27 , pp. 37-42
    • Zielińska, M.1    Hilgier, W.2    Borkowska, H.D.3    Oja, S.S.4    Saransaari, P.5    Goryński, P.6    Albrecht, J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.