-
1
-
-
84873606312
-
Annual Report to the Nation on the Status of Cancer, 1975-2009, featuring the burden and trends in human papillomavirus(HPV)-associated cancers and HPV vaccination coverage levels
-
Jemal A, Simard EP, Dorell C, Noone AM, Markowitz LE, Kohler B, Eheman C, Saraiya M, Bandi P, Saslow D, Cronin KA, Watson M, Schiffman M, Henley SJ, Schymura MJ, Anderson RN, et al. Annual Report to the Nation on the Status of Cancer, 1975-2009, featuring the burden and trends in human papillomavirus(HPV)-associated cancers and HPV vaccination coverage levels. Journal of the National Cancer Institute. 2013; 105:175-201.
-
(2013)
Journal of the National Cancer Institute
, vol.105
, pp. 175-201
-
-
Jemal, A.1
Simard, E.P.2
Dorell, C.3
Noone, A.M.4
Markowitz, L.E.5
Kohler, B.6
Eheman, C.7
Saraiya, M.8
Bandi, P.9
Saslow, D.10
Cronin, K.A.11
Watson, M.12
Schiffman, M.13
Henley, S.J.14
Schymura, M.J.15
Anderson, R.N.16
-
4
-
-
0032756946
-
The changing epidemiology of esophageal cancer
-
Blot WJ, McLaughlin JK. The changing epidemiology of esophageal cancer. Seminars in oncology. 1999; 26:2-8.
-
(1999)
Seminars in oncology
, vol.26
, pp. 2-8
-
-
Blot, W.J.1
McLaughlin, J.K.2
-
5
-
-
0025237246
-
Impact of esophageal screening in patients with head and neck cancer
-
Atabek U, Mohit-Tabatabai MA, Rush BF, Ohanian M, Rovelli P. Impact of esophageal screening in patients with head and neck cancer. The American surgeon. 1990; 56:289-292.
-
(1990)
The American surgeon
, vol.56
, pp. 289-292
-
-
Atabek, U.1
Mohit-Tabatabai, M.A.2
Rush, B.F.3
Ohanian, M.4
Rovelli, P.5
-
6
-
-
0030850474
-
A prospective, seroepidemiological study of the role of human papillomavirus in esophageal cancer in Norway
-
Bjorge T, Hakulinen T, Engeland A, Jellum E, Koskela P, Lehtinen M, Luostarinen T, Paavonen J, Sapp M, Schiller J, Thoresen S, Wang Z, Youngman L, Dillner J. A prospective, seroepidemiological study of the role of human papillomavirus in esophageal cancer in Norway. Cancer research. 1997; 57:3989-3992.
-
(1997)
Cancer research
, vol.57
, pp. 3989-3992
-
-
Bjorge, T.1
Hakulinen, T.2
Engeland, A.3
Jellum, E.4
Koskela, P.5
Lehtinen, M.6
Luostarinen, T.7
Paavonen, J.8
Sapp, M.9
Schiller, J.10
Thoresen, S.11
Wang, Z.12
Youngman, L.13
Dillner, J.14
-
8
-
-
0026039730
-
Barrett's esophagus and esophageal adenocarcinoma
-
Reid BJ. Barrett's esophagus and esophageal adenocarcinoma. Gastroenterology clinics of North America. 1991; 20:817-834.
-
(1991)
Gastroenterology clinics of North America
, vol.20
, pp. 817-834
-
-
Reid, B.J.1
-
10
-
-
23844457288
-
Phase II trial of oxaliplatin, leucovorin and fluorouracil in patients with advanced carcinoma of the esophagus
-
Mauer AM, Kraut EH, Krauss SA, Ansari RH, Kasza K, Szeto L, Vokes EE. Phase II trial of oxaliplatin, leucovorin and fluorouracil in patients with advanced carcinoma of the esophagus. Annals of oncology: official journal of the European Society for Medical Oncology/ESMO. 2005; 16:1320-1325.
-
(2005)
Annals of oncology: official journal of the European Society for Medical Oncology/ESMO
, vol.16
, pp. 1320-1325
-
-
Mauer, A.M.1
Kraut, E.H.2
Krauss, S.A.3
Ansari, R.H.4
Kasza, K.5
Szeto, L.6
Vokes, E.E.7
-
11
-
-
0032887574
-
Phase II trial of weekly irinotecan plus cisplatin in advanced esophageal cancer
-
Ilson DH, Saltz L, Enzinger P, Huang Y, Kornblith A, Gollub M, O'Reilly E, Schwartz G, DeGroff J, Gonzalez G, Kelsen DP. Phase II trial of weekly irinotecan plus cisplatin in advanced esophageal cancer. Journal of clinical oncology: official journal of the American Society of Clinical Oncology. 1999; 17:3270-3275.
-
(1999)
Journal of clinical oncology: official journal of the American Society of Clinical Oncology
, vol.17
, pp. 3270-3275
-
-
Ilson, D.H.1
Saltz, L.2
Enzinger, P.3
Huang, Y.4
Kornblith, A.5
Gollub, M.6
O'Reilly, E.7
Schwartz, G.8
DeGroff, J.9
Gonzalez, G.10
Kelsen, D.P.11
-
13
-
-
84899747138
-
Identification of genomic alterations in oesophageal squamous cell cancer
-
Song Y, Li L, Ou Y, Gao Z, Li E, Li X, Zhang W, Wang J, Xu L, Zhou Y, Ma X, Liu L, Zhao Z, Huang X, Fan J, Dong L, et al. Identification of genomic alterations in oesophageal squamous cell cancer. Nature. 2014; 509:91-95.
-
(2014)
Nature
, vol.509
, pp. 91-95
-
-
Song, Y.1
Li, L.2
Ou, Y.3
Gao, Z.4
Li, E.5
Li, X.6
Zhang, W.7
Wang, J.8
Xu, L.9
Zhou, Y.10
Ma, X.11
Liu, L.12
Zhao, Z.13
Huang, X.14
Fan, J.15
Dong, L.16
-
14
-
-
84878593111
-
Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity
-
Dulak AM, Stojanov P, Peng S, Lawrence MS, Fox C, Stewart C, Bandla S, Imamura Y, Schumacher SE, Shefler E, McKenna A, Carter SL, Cibulskis K, Sivachenko A, Saksena G, Voet D, et al. Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity. Nature genetics. 2013; 45:478-486.
-
(2013)
Nature genetics
, vol.45
, pp. 478-486
-
-
Dulak, A.M.1
Stojanov, P.2
Peng, S.3
Lawrence, M.S.4
Fox, C.5
Stewart, C.6
Bandla, S.7
Imamura, Y.8
Schumacher, S.E.9
Shefler, E.10
McKenna, A.11
Carter, S.L.12
Cibulskis, K.13
Sivachenko, A.14
Saksena, G.15
Voet, D.16
-
15
-
-
3042807464
-
Tyrosine kinase receptors as attractive targets of cancer therapy
-
Bennasroune A, Gardin A, Aunis D, Cremel G, Hubert P. Tyrosine kinase receptors as attractive targets of cancer therapy. Critical reviews in oncology/hematology. 2004; 50:23-38.
-
(2004)
Critical reviews in oncology/hematology
, vol.50
, pp. 23-38
-
-
Bennasroune, A.1
Gardin, A.2
Aunis, D.3
Cremel, G.4
Hubert, P.5
-
16
-
-
72549119534
-
Targeted therapies: the rare cancer paradigm
-
Pierotti MA, Negri T, Tamborini E, Perrone F, Pricl S, Pilotti S. Targeted therapies: the rare cancer paradigm. Molecular oncology. 2010; 4:19-37.
-
(2010)
Molecular oncology
, vol.4
, pp. 19-37
-
-
Pierotti, M.A.1
Negri, T.2
Tamborini, E.3
Perrone, F.4
Pricl, S.5
Pilotti, S.6
-
17
-
-
48249158391
-
Structure-based view of epidermal growth factor receptor regulation
-
Ferguson KM. Structure-based view of epidermal growth factor receptor regulation. Annual review of biophysics. 2008; 37:353-373.
-
(2008)
Annual review of biophysics
, vol.37
, pp. 353-373
-
-
Ferguson, K.M.1
-
18
-
-
0036118262
-
Epidermal growth factor receptor family in lung cancer and premalignancy
-
Franklin WA, Veve R, Hirsch FR, Helfrich BA, Bunn PA, Jr. Epidermal growth factor receptor family in lung cancer and premalignancy. Seminars in oncology. 2002; 29:3-14.
-
(2002)
Seminars in oncology
, vol.29
, pp. 3-14
-
-
Franklin, W.A.1
Veve, R.2
Hirsch, F.R.3
Helfrich, B.A.4
Bunn, P.A.5
-
19
-
-
42649145667
-
Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer
-
Amado RG, Wolf M, Peeters M, Van Cutsem E, Siena S, Freeman DJ, Juan T, Sikorski R, Suggs S, Radinsky R, Patterson SD, Chang DD. Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer. Journal of clinical oncology: official journal of the American Society of Clinical Oncology. 2008; 26:1626-1634.
-
(2008)
Journal of clinical oncology: official journal of the American Society of Clinical Oncology
, vol.26
, pp. 1626-1634
-
-
Amado, R.G.1
Wolf, M.2
Peeters, M.3
Van Cutsem, E.4
Siena, S.5
Freeman, D.J.6
Juan, T.7
Sikorski, R.8
Suggs, S.9
Radinsky, R.10
Patterson, S.D.11
Chang, D.D.12
-
20
-
-
54949085398
-
K-ras mutations and benefit from cetuximab in advanced colorectal cancer
-
Karapetis CS, Khambata-Ford S, Jonker DJ, O'Callaghan CJ, Tu D, Tebbutt NC, Simes RJ, Chalchal H, Shapiro JD, Robitaille S, Price TJ, Shepherd L, Au HJ, Langer C, Moore MJ, Zalcberg JR. K-ras mutations and benefit from cetuximab in advanced colorectal cancer. The New England journal of medicine. 2008; 359:1757-1765.
-
(2008)
The New England journal of medicine
, vol.359
, pp. 1757-1765
-
-
Karapetis, C.S.1
Khambata-Ford, S.2
Jonker, D.J.3
O'Callaghan, C.J.4
Tu, D.5
Tebbutt, N.C.6
Simes, R.J.7
Chalchal, H.8
Shapiro, J.D.9
Robitaille, S.10
Price, T.J.11
Shepherd, L.12
Au, H.J.13
Langer, C.14
Moore, M.J.15
Zalcberg, J.R.16
-
21
-
-
33646706077
-
Gefitinib-sensitizing mutations in esophageal carcinoma
-
Guo M, Liu S, Lu F. Gefitinib-sensitizing mutations in esophageal carcinoma. The New England journal of medicine. 2006; 354:2193-2194.
-
(2006)
The New England journal of medicine
, vol.354
, pp. 2193-2194
-
-
Guo, M.1
Liu, S.2
Lu, F.3
-
22
-
-
78650978994
-
Epidermal growth factor receptor (EGFR) is overexpressed in highgrade dysplasia and adenocarcinoma of the esophagus and may represent a biomarker of histological progression in Barrett's esophagus (BE)
-
Cronin J, McAdam E, Danikas A, Tselepis C, Griffiths P, Baxter J, Thomas L, Manson J, Jenkins G. Epidermal growth factor receptor (EGFR) is overexpressed in highgrade dysplasia and adenocarcinoma of the esophagus and may represent a biomarker of histological progression in Barrett's esophagus (BE). The American journal of gastroenterology. 2011; 106:46-56.
-
(2011)
The American journal of gastroenterology
, vol.106
, pp. 46-56
-
-
Cronin, J.1
McAdam, E.2
Danikas, A.3
Tselepis, C.4
Griffiths, P.5
Baxter, J.6
Thomas, L.7
Manson, J.8
Jenkins, G.9
-
23
-
-
60749095127
-
Anti-epidermal growth factor receptor monoclonal antibody cetuximab inhibits EGFR/HER-2 heterodimerization and activation
-
Patel D, Bassi R, Hooper A, Prewett M, Hicklin DJ, Kang X. Anti-epidermal growth factor receptor monoclonal antibody cetuximab inhibits EGFR/HER-2 heterodimerization and activation. International journal of oncology. 2009; 34:25-32.
-
(2009)
International journal of oncology
, vol.34
, pp. 25-32
-
-
Patel, D.1
Bassi, R.2
Hooper, A.3
Prewett, M.4
Hicklin, D.J.5
Kang, X.6
-
24
-
-
79951532484
-
CALGB 80403/ECOG 1206: a randomized phase II study of three standard chemotherapy regimens plus cetuximab in metastatic esophageal and GE junction cancer
-
Enzinger PC, Burtness B, Hollis DM, Niedzwiecki D, Ilson D, Benson AB, Mayer RJ, Goldberg RM. CALGB 80403/ECOG 1206: a randomized phase II study of three standard chemotherapy regimens plus cetuximab in metastatic esophageal and GE junction cancer. Journal of Clinical Oncology, ASCO Annual Meeting Abstracts. 2010; 28:4006.
-
(2010)
Journal of Clinical Oncology, ASCO Annual Meeting Abstracts
, vol.28
, pp. 4006
-
-
Enzinger, P.C.1
Burtness, B.2
Hollis, D.M.3
Niedzwiecki, D.4
Ilson, D.5
Benson, A.B.6
Mayer, R.J.7
Goldberg, R.M.8
-
25
-
-
70349641356
-
Cetuximab plus cisplatin-5-fluorouracil versus cisplatin-5-fluorouracil alone in first-line metastatic squamous cell carcinoma of the esophagus: a randomized phase II study of the Arbeitsgemeinschaft Internistische Onkologie
-
Lorenzen S, Schuster T, Porschen R, Al-Batran SE, Hofheinz R, Thuss-Patience P, Moehler M, Grabowski P, Arnold D, Greten T, Muller L, Rothling N, Peschel C, Langer R, Lordick F. Cetuximab plus cisplatin-5-fluorouracil versus cisplatin-5-fluorouracil alone in first-line metastatic squamous cell carcinoma of the esophagus: a randomized phase II study of the Arbeitsgemeinschaft Internistische Onkologie. Annals of oncology: official journal of the European Society for Medical Oncology/ESMO. 2009; 20:1667-1673.
-
(2009)
Annals of oncology: official journal of the European Society for Medical Oncology/ESMO
, vol.20
, pp. 1667-1673
-
-
Lorenzen, S.1
Schuster, T.2
Porschen, R.3
Al-Batran, S.E.4
Hofheinz, R.5
Thuss-Patience, P.6
Moehler, M.7
Grabowski, P.8
Arnold, D.9
Greten, T.10
Muller, L.11
Rothling, N.12
Peschel, C.13
Langer, R.14
Lordick, F.15
-
26
-
-
79957834501
-
A multicenter phase II trial of single-agent cetuximab in advanced esophageal and gastric adenocarcinoma
-
Chan JA, Blaszkowsky LS, Enzinger PC, Ryan DP, Abrams TA, Zhu AX, Temel JS, Schrag D, Bhargava P, Meyerhardt JA, Wolpin BM, Fidias P, Zheng H, Florio S, Regan E, Fuchs CS. A multicenter phase II trial of single-agent cetuximab in advanced esophageal and gastric adenocarcinoma. Annals of oncology: official journal of the European Society for Medical Oncology/ESMO. 2011; 22:1367-1373.
-
(2011)
Annals of oncology: official journal of the European Society for Medical Oncology/ESMO
, vol.22
, pp. 1367-1373
-
-
Chan, J.A.1
Blaszkowsky, L.S.2
Enzinger, P.C.3
Ryan, D.P.4
Abrams, T.A.5
Zhu, A.X.6
Temel, J.S.7
Schrag, D.8
Bhargava, P.9
Meyerhardt, J.A.10
Wolpin, B.M.11
Fidias, P.12
Zheng, H.13
Florio, S.14
Regan, E.15
Fuchs, C.S.16
-
27
-
-
84876951761
-
Capecitabine and cisplatin with or without cetuximab for patients with previously untreated advanced gastric cancer (EXPAND): a randomised, open-label phase 3 trial
-
Lordick F, Kang YK, Chung HC, Salman P, Oh SC, Bodoky G, Kurteva G, Volovat C, Moiseyenko VM, Gorbunova V, Park JO, Sawaki A, Celik I, Gotte H, Melezinkova H, Moehler M, et al. Capecitabine and cisplatin with or without cetuximab for patients with previously untreated advanced gastric cancer (EXPAND): a randomised, open-label phase 3 trial. The lancet oncology. 2013; 14:490-499.
-
(2013)
The lancet oncology
, vol.14
, pp. 490-499
-
-
Lordick, F.1
Kang, Y.K.2
Chung, H.C.3
Salman, P.4
Oh, S.C.5
Bodoky, G.6
Kurteva, G.7
Volovat, C.8
Moiseyenko, V.M.9
Gorbunova, V.10
Park, J.O.11
Sawaki, A.12
Celik, I.13
Gotte, H.14
Melezinkova, H.15
Moehler, M.16
-
28
-
-
84861984671
-
A pilot study of nimotuzumab combined with cisplatin and 5-FU in patients with advanced esophageal squamous cell carcinoma
-
Ling Y, Chen J, Tao M, Chu X, Zhang X. A pilot study of nimotuzumab combined with cisplatin and 5-FU in patients with advanced esophageal squamous cell carcinoma. Journal of thoracic disease. 2012; 4:58-62.
-
(2012)
Journal of thoracic disease
, vol.4
, pp. 58-62
-
-
Ling, Y.1
Chen, J.2
Tao, M.3
Chu, X.4
Zhang, X.5
-
29
-
-
84876992498
-
Epirubicin, oxaliplatin, and capecitabine with or without panitumumab for patients with previously untreated advanced oesophagogastric cancer (REAL3): a randomised, open-label phase 3 trial
-
Waddell T, Chau I, Cunningham D, Gonzalez D, Okines AF, Okines C, Wotherspoon A, Saffery C, Middleton G, Wadsley J, Ferry D, Mansoor W, Crosby T, Coxon F, Smith D, Waters J, et al. Epirubicin, oxaliplatin, and capecitabine with or without panitumumab for patients with previously untreated advanced oesophagogastric cancer (REAL3): a randomised, open-label phase 3 trial. The lancet oncology. 2013; 14:481-489.
-
(2013)
The lancet oncology
, vol.14
, pp. 481-489
-
-
Waddell, T.1
Chau, I.2
Cunningham, D.3
Gonzalez, D.4
Okines, A.F.5
Okines, C.6
Wotherspoon, A.7
Saffery, C.8
Middleton, G.9
Wadsley, J.10
Ferry, D.11
Mansoor, W.12
Crosby, T.13
Coxon, F.14
Smith, D.15
Waters, J.16
-
30
-
-
77649085714
-
A phase II study of perioperative concurrent chemotherapy, gefitinib, and hyperfractionated radiation followed by maintenance gefitinib in locoregionally advanced esophagus and gastroesophageal junction cancer
-
Rodriguez CP, Adelstein DJ, Rice TW, Rybicki LA, Videtic GM, Saxton JP, Murthy SC, Mason DP, Ives DI. A phase II study of perioperative concurrent chemotherapy, gefitinib, and hyperfractionated radiation followed by maintenance gefitinib in locoregionally advanced esophagus and gastroesophageal junction cancer. Journal of thoracic oncology: official publication of the International Association for the Study of Lung Cancer. 2010; 5:229-235.
-
(2010)
Journal of thoracic oncology: official publication of the International Association for the Study of Lung Cancer
, vol.5
, pp. 229-235
-
-
Rodriguez, C.P.1
Adelstein, D.J.2
Rice, T.W.3
Rybicki, L.A.4
Videtic, G.M.5
Saxton, J.P.6
Murthy, S.C.7
Mason, D.P.8
Ives, D.I.9
-
31
-
-
84866733910
-
A phase II trial of gefitinib for recurrent or metastatic cancer of the esophagus or gastroesophageal junction
-
Adelstein DJ, Rodriguez CP, Rybicki LA, Ives DI, Rice TW. A phase II trial of gefitinib for recurrent or metastatic cancer of the esophagus or gastroesophageal junction. Investigational new drugs. 2012; 30:1684-1689.
-
(2012)
Investigational new drugs
, vol.30
, pp. 1684-1689
-
-
Adelstein, D.J.1
Rodriguez, C.P.2
Rybicki, L.A.3
Ives, D.I.4
Rice, T.W.5
-
32
-
-
78549279090
-
Phase II study of concurrent chemoradiation in combination with erlotinib for locally advanced esophageal carcinoma
-
Li G, Hu W, Wang J, Deng X, Zhang P, Zhang X, Xie C, Wu S. Phase II study of concurrent chemoradiation in combination with erlotinib for locally advanced esophageal carcinoma. International journal of radiation oncology, biology, physics. 2010; 78:1407-1412.
-
(2010)
International journal of radiation oncology, biology, physics
, vol.78
, pp. 1407-1412
-
-
Li, G.1
Hu, W.2
Wang, J.3
Deng, X.4
Zhang, P.5
Zhang, X.6
Xie, C.7
Wu, S.8
-
33
-
-
33750618860
-
Phase II trial of erlotinib in gastroesophageal junction and gastric adenocarcinomas: SWOG 0127
-
Dragovich T, McCoy S, Fenoglio-Preiser CM, Wang J, Benedetti JK, Baker AF, Hackett CB, Urba SG, Zaner KS, Blanke CD, Abbruzzese JL. Phase II trial of erlotinib in gastroesophageal junction and gastric adenocarcinomas: SWOG 0127. Journal of clinical oncology: official journal of the American Society of Clinical Oncology. 2006; 24:4922-4927.
-
(2006)
Journal of clinical oncology: official journal of the American Society of Clinical Oncology
, vol.24
, pp. 4922-4927
-
-
Dragovich, T.1
McCoy, S.2
Fenoglio-Preiser, C.M.3
Wang, J.4
Benedetti, J.K.5
Baker, A.F.6
Hackett, C.B.7
Urba, S.G.8
Zaner, K.S.9
Blanke, C.D.10
Abbruzzese, J.L.11
-
34
-
-
0022406444
-
Amplification of a novel v-erbB-related gene in a human mammary carcinoma
-
King CR, Kraus MH, Aaronson SA. Amplification of a novel v-erbB-related gene in a human mammary carcinoma. Science. 1985; 229:974-976.
-
(1985)
Science
, vol.229
, pp. 974-976
-
-
King, C.R.1
Kraus, M.H.2
Aaronson, S.A.3
-
35
-
-
2342488965
-
Update on HER-2 as a target for cancer therapy: intracellular signaling pathways of ErbB2/HER-2 and family members
-
Olayioye MA. Update on HER-2 as a target for cancer therapy: intracellular signaling pathways of ErbB2/HER-2 and family members. Breast cancer research: BCR. 2001; 3:385-389.
-
(2001)
Breast cancer research: BCR
, vol.3
, pp. 385-389
-
-
Olayioye, M.A.1
-
36
-
-
0022486379
-
Amplification of c-erbB-2 oncogene in human adenocarcinomas in vivo
-
Yokota J, Yamamoto T, Toyoshima K, Terada M, Sugimura T, Battifora H, Cline MJ. Amplification of c-erbB-2 oncogene in human adenocarcinomas in vivo. Lancet. 1986; 1:765-767.
-
(1986)
Lancet
, vol.1
, pp. 765-767
-
-
Yokota, J.1
Yamamoto, T.2
Toyoshima, K.3
Terada, M.4
Sugimura, T.5
Battifora, H.6
Cline, M.J.7
-
37
-
-
0024337144
-
Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer
-
Slamon DJ, Godolphin W, Jones LA, Holt JA, Wong SG, Keith DE, Levin WJ, Stuart SG, Udove J, Ullrich A, et al. Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science. 1989; 244:707-712.
-
(1989)
Science
, vol.244
, pp. 707-712
-
-
Slamon, D.J.1
Godolphin, W.2
Jones, L.A.3
Holt, J.A.4
Wong, S.G.5
Keith, D.E.6
Levin, W.J.7
Stuart, S.G.8
Udove, J.9
Ullrich, A.10
-
38
-
-
0029991439
-
Phase II study of weekly intravenous recombinant humanized anti-p185HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer
-
Baselga J, Tripathy D, Mendelsohn J, Baughman S, Benz CC, Dantis L, Sklarin NT, Seidman AD, Hudis CA, Moore J, Rosen PP, Twaddell T, Henderson IC, Norton L. Phase II study of weekly intravenous recombinant humanized anti-p185HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer. Journal of clinical oncology: official journal of the American Society of Clinical Oncology. 1996; 14:737-744.
-
(1996)
Journal of clinical oncology: official journal of the American Society of Clinical Oncology
, vol.14
, pp. 737-744
-
-
Baselga, J.1
Tripathy, D.2
Mendelsohn, J.3
Baughman, S.4
Benz, C.C.5
Dantis, L.6
Sklarin, N.T.7
Seidman, A.D.8
Hudis, C.A.9
Moore, J.10
Rosen, P.P.11
Twaddell, T.12
Henderson, I.C.13
Norton, L.14
-
39
-
-
0034929997
-
The HER-2/neu oncogene in tumors of the gastrointestinal tract
-
Ross JS, McKenna BJ. The HER-2/neu oncogene in tumors of the gastrointestinal tract. Cancer investigation. 2001; 19:554-568.
-
(2001)
Cancer investigation
, vol.19
, pp. 554-568
-
-
Ross, J.S.1
McKenna, B.J.2
-
40
-
-
84865429022
-
Efficacy of trastuzumab in Japanese patients with HER2-positive advanced gastric or gastroesophageal junction cancer: a subgroup analysis of the Trastuzumab for Gastric Cancer (ToGA) study
-
Sawaki A, Ohashi Y, Omuro Y, Satoh T, Hamamoto Y, Boku N, Miyata Y, Takiuchi H, Yamaguchi K, Sasaki Y, Nishina T, Satoh A, Baba E, Tamura T, Abe T, Hatake K, et al. Efficacy of trastuzumab in Japanese patients with HER2-positive advanced gastric or gastroesophageal junction cancer: a subgroup analysis of the Trastuzumab for Gastric Cancer (ToGA) study. Gastric cancer: official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association. 2012; 15:313-322.
-
(2012)
Gastric cancer: official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association
, vol.15
, pp. 313-322
-
-
Sawaki, A.1
Ohashi, Y.2
Omuro, Y.3
Satoh, T.4
Hamamoto, Y.5
Boku, N.6
Miyata, Y.7
Takiuchi, H.8
Yamaguchi, K.9
Sasaki, Y.10
Nishina, T.11
Satoh, A.12
Baba, E.13
Tamura, T.14
Abe, T.15
Hatake, K.16
-
41
-
-
56549113680
-
A phase III randomized comparison of lapatinib plus capecitabine versus capecitabine alone in women with advanced breast cancer that has progressed on trastuzumab: updated efficacy and biomarker analyses
-
Cameron D, Casey M, Press M, Lindquist D, Pienkowski T, Romieu CG, Chan S, Jagiello-Gruszfeld A, Kaufman B, Crown J, Chan A, Campone M, Viens P, Davidson N, Gorbounova V, Raats JI, et al. A phase III randomized comparison of lapatinib plus capecitabine versus capecitabine alone in women with advanced breast cancer that has progressed on trastuzumab: updated efficacy and biomarker analyses. Breast cancer research and treatment. 2008; 112:533-543.
-
(2008)
Breast cancer research and treatment
, vol.112
, pp. 533-543
-
-
Cameron, D.1
Casey, M.2
Press, M.3
Lindquist, D.4
Pienkowski, T.5
Romieu, C.G.6
Chan, S.7
Jagiello-Gruszfeld, A.8
Kaufman, B.9
Crown, J.10
Chan, A.11
Campone, M.12
Viens, P.13
Davidson, N.14
Gorbounova, V.15
Raats, J.I.16
-
42
-
-
77953453066
-
Lapatinib monotherapy in recurrent upper gastrointestinal malignancy: phase II efficacy and biomarker analyses
-
(Abstract 43)
-
Hecht JR, Urba S, Koehler M, Ellis C, Gagnon R, Kemner A, et al. Lapatinib monotherapy in recurrent upper gastrointestinal malignancy: phase II efficacy and biomarker analyses. Gastrointestinal Cancers Symposium. 2008; (Abstract 43).
-
(2008)
Gastrointestinal Cancers Symposium
-
-
Hecht, J.R.1
Urba, S.2
Koehler, M.3
Ellis, C.4
Gagnon, R.5
Kemner, A.6
-
45
-
-
30944452172
-
Genomic amplification of MET with boundaries within fragile site FRA7G and upregulation of MET pathways in esophageal adenocarcinoma
-
Miller CT, Lin L, Casper AM, Lim J, Thomas DG, Orringer MB, Chang AC, Chambers AF, Giordano TJ, Glover TW, Beer DG. Genomic amplification of MET with boundaries within fragile site FRA7G and upregulation of MET pathways in esophageal adenocarcinoma. Oncogene. 2006; 25:409-418.
-
(2006)
Oncogene
, vol.25
, pp. 409-418
-
-
Miller, C.T.1
Lin, L.2
Casper, A.M.3
Lim, J.4
Thomas, D.G.5
Orringer, M.B.6
Chang, A.C.7
Chambers, A.F.8
Giordano, T.J.9
Glover, T.W.10
Beer, D.G.11
-
46
-
-
0033135820
-
The prognostic significance of amplification and overexpression of c-met and c-erb B-2 in human gastric carcinomas
-
Nakajima M, Sawada H, Yamada Y, Watanabe A, Tatsumi M, Yamashita J, Matsuda M, Sakaguchi T, Hirao T, Nakano H. The prognostic significance of amplification and overexpression of c-met and c-erb B-2 in human gastric carcinomas. Cancer. 1999; 85:1894-1902.
-
(1999)
Cancer
, vol.85
, pp. 1894-1902
-
-
Nakajima, M.1
Sawada, H.2
Yamada, Y.3
Watanabe, A.4
Tatsumi, M.5
Yamashita, J.6
Matsuda, M.7
Sakaguchi, T.8
Hirao, T.9
Nakano, H.10
-
47
-
-
84555190809
-
MET amplification identifies a small and aggressive subgroup of esophagogastric adenocarcinoma with evidence of responsiveness to crizotinib
-
Lennerz JK, Kwak EL, Ackerman A, Michael M, Fox SB, Bergethon K, Lauwers GY, Christensen JG, Wilner KD, Haber DA, Salgia R, Bang YJ, Clark JW, Solomon BJ, Iafrate AJ. MET amplification identifies a small and aggressive subgroup of esophagogastric adenocarcinoma with evidence of responsiveness to crizotinib. Journal of clinical oncology: official journal of the American Society of Clinical Oncology. 2011; 29:4803-4810.
-
(2011)
Journal of clinical oncology: official journal of the American Society of Clinical Oncology
, vol.29
, pp. 4803-4810
-
-
Lennerz, J.K.1
Kwak, E.L.2
Ackerman, A.3
Michael, M.4
Fox, S.B.5
Bergethon, K.6
Lauwers, G.Y.7
Christensen, J.G.8
Wilner, K.D.9
Haber, D.A.10
Salgia, R.11
Bang, Y.J.12
Clark, J.W.13
Solomon, B.J.14
Iafrate, A.J.15
-
48
-
-
84905028489
-
Rilotumumab in combination with epirubicin, cisplatin, and capecitabine as first-line treatment for gastric or oesophagogastric junction adenocarcinoma: an openlabel, dose de-escalation phase 1b study and a double-blind, randomised phase 2 study
-
Iveson T, Donehower RC, Davidenko I, Tjulandin S, Deptala A, Harrison M, Nirni S, Lakshmaiah K, Thomas A, Jiang Y, Zhu M, Tang R, Anderson A, Dubey S, Oliner KS, Loh E. Rilotumumab in combination with epirubicin, cisplatin, and capecitabine as first-line treatment for gastric or oesophagogastric junction adenocarcinoma: an openlabel, dose de-escalation phase 1b study and a double-blind, randomised phase 2 study. The lancet oncology. 2014; 15:1007-1018.
-
(2014)
The lancet oncology
, vol.15
, pp. 1007-1018
-
-
Iveson, T.1
Donehower, R.C.2
Davidenko, I.3
Tjulandin, S.4
Deptala, A.5
Harrison, M.6
Nirni, S.7
Lakshmaiah, K.8
Thomas, A.9
Jiang, Y.10
Zhu, M.11
Tang, R.12
Anderson, A.13
Dubey, S.14
Oliner, K.S.15
Loh, E.16
-
49
-
-
34249075147
-
MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling
-
Engelman JA, Zejnullahu K, Mitsudomi T, Song Y, Hyland C, Park JO, Lindeman N, Gale CM, Zhao X, Christensen J, Kosaka T, Holmes AJ, Rogers AM, Cappuzzo F, Mok T, Lee C, et al. MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling. Science. 2007; 316:1039-1043.
-
(2007)
Science
, vol.316
, pp. 1039-1043
-
-
Engelman, J.A.1
Zejnullahu, K.2
Mitsudomi, T.3
Song, Y.4
Hyland, C.5
Park, J.O.6
Lindeman, N.7
Gale, C.M.8
Zhao, X.9
Christensen, J.10
Kosaka, T.11
Holmes, A.J.12
Rogers, A.M.13
Cappuzzo, F.14
Mok, T.15
Lee, C.16
-
52
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
Hurwitz H, Fehrenbacher L, Novotny W, Cartwright T, Hainsworth J, Heim W, Berlin J, Baron A, Griffing S, Holmgren E, Ferrara N, Fyfe G, Rogers B, Ross R, Kabbinavar F. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. The New England journal of medicine. 2004; 350:2335-2342.
-
(2004)
The New England journal of medicine
, vol.350
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
Cartwright, T.4
Hainsworth, J.5
Heim, W.6
Berlin, J.7
Baron, A.8
Griffing, S.9
Holmgren, E.10
Ferrara, N.11
Fyfe, G.12
Rogers, B.13
Ross, R.14
Kabbinavar, F.15
-
53
-
-
33846629672
-
Multicenter phase II study of irinotecan, cisplatin, and bevacizumab in patients with metastatic gastric or gastroesophageal junction adenocarcinoma
-
Shah MA, Ramanathan RK, Ilson DH, Levnor A, D'Adamo D, O'Reilly E, Tse A, Trocola R, Schwartz L, Capanu M, Schwartz GK, Kelsen DP. Multicenter phase II study of irinotecan, cisplatin, and bevacizumab in patients with metastatic gastric or gastroesophageal junction adenocarcinoma. Journal of clinical oncology: official journal of the American Society of Clinical Oncology. 2006; 24:5201-5206.
-
(2006)
Journal of clinical oncology: official journal of the American Society of Clinical Oncology
, vol.24
, pp. 5201-5206
-
-
Shah, M.A.1
Ramanathan, R.K.2
Ilson, D.H.3
Levnor, A.4
D'Adamo, D.5
O'Reilly, E.6
Tse, A.7
Trocola, R.8
Schwartz, L.9
Capanu, M.10
Schwartz, G.K.11
Kelsen, D.P.12
-
54
-
-
79952355358
-
Phase II study of modified docetaxel, cisplatin, and fluorouracil with bevacizumab in patients with metastatic gastroesophageal adenocarcinoma
-
Shah MA, Jhawer M, Ilson DH, Lefkowitz RA, Robinson E, Capanu M, Kelsen DP. Phase II study of modified docetaxel, cisplatin, and fluorouracil with bevacizumab in patients with metastatic gastroesophageal adenocarcinoma. Journal of clinical oncology: official journal of the American Society of Clinical Oncology. 2011; 29:868-874.
-
(2011)
Journal of clinical oncology: official journal of the American Society of Clinical Oncology
, vol.29
, pp. 868-874
-
-
Shah, M.A.1
Jhawer, M.2
Ilson, D.H.3
Lefkowitz, R.A.4
Robinson, E.5
Capanu, M.6
Kelsen, D.P.7
-
55
-
-
84918563179
-
-
Cancer discovery
-
Ramucirumab approved for gastric cancer . Cancer discovery. 2014; 4:752-753.
-
(2014)
, vol.4
, pp. 752-753
-
-
-
56
-
-
84892852372
-
Ramucirumab monotherapy for previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (REGARD): an international, randomised, multicentre, placebo-controlled, phase 3 trial
-
Fuchs CS, Tomasek J, Yong CJ, Dumitru F, Passalacqua R, Goswami C, Safran H, dos Santos LV, Aprile G, Ferry DR, Melichar B, Tehfe M, Topuzov E, Zalcberg JR, Chau I, Campbell W, et al. Ramucirumab monotherapy for previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (REGARD): an international, randomised, multicentre, placebo-controlled, phase 3 trial. Lancet. 2014; 383:31-39.
-
(2014)
Lancet
, vol.383
, pp. 31-39
-
-
Fuchs, C.S.1
Tomasek, J.2
Yong, C.J.3
Dumitru, F.4
Passalacqua, R.5
Goswami, C.6
Safran, H.7
dos Santos, L.V.8
Aprile, G.9
Ferry, D.R.10
Melichar, B.11
Tehfe, M.12
Topuzov, E.13
Zalcberg, J.R.14
Chau, I.15
Campbell, W.16
-
57
-
-
82955241985
-
Phase II study of sunitinib as second-line treatment for advanced gastric cancer
-
Bang YJ, Kang YK, Kang WK, Boku N, Chung HC, Chen JS, Doi T, Sun Y, Shen L, Qin S, Ng WT, Tursi JM, Lechuga MJ, Lu DR, Ruiz-Garcia A, Sobrero A. Phase II study of sunitinib as second-line treatment for advanced gastric cancer. Investigational new drugs. 2011; 29:1449-1458.
-
(2011)
Investigational new drugs
, vol.29
, pp. 1449-1458
-
-
Bang, Y.J.1
Kang, Y.K.2
Kang, W.K.3
Boku, N.4
Chung, H.C.5
Chen, J.S.6
Doi, T.7
Sun, Y.8
Shen, L.9
Qin, S.10
Ng, W.T.11
Tursi, J.M.12
Lechuga, M.J.13
Lu, D.R.14
Ruiz-Garcia, A.15
Sobrero, A.16
-
58
-
-
77954574658
-
Phase II study of sorafenib in combination with docetaxel and cisplatin in the treatment of metastatic or advanced gastric and gastroesophageal junction adenocarcinoma: ECOG 5203
-
Sun W, Powell M, O'Dwyer PJ, Catalano P, Ansari RH, Benson AB. Phase II study of sorafenib in combination with docetaxel and cisplatin in the treatment of metastatic or advanced gastric and gastroesophageal junction adenocarcinoma: ECOG 5203. Journal of clinical oncology: official journal of the American Society of Clinical Oncology. 2010; 28:2947-2951.
-
(2010)
Journal of clinical oncology: official journal of the American Society of Clinical Oncology
, vol.28
, pp. 2947-2951
-
-
Sun, W.1
Powell, M.2
O'Dwyer, P.J.3
Catalano, P.4
Ansari, R.H.5
Benson, A.B.6
-
60
-
-
80053944035
-
Targeting Axl and Mer kinases in cancer
-
Verma A, Warner SL, Vankayalapati H, Bearss DJ, Sharma S. Targeting Axl and Mer kinases in cancer. Molecular cancer therapeutics. 2011; 10:1763-1773.
-
(2011)
Molecular cancer therapeutics
, vol.10
, pp. 1763-1773
-
-
Verma, A.1
Warner, S.L.2
Vankayalapati, H.3
Bearss, D.J.4
Sharma, S.5
-
61
-
-
0027202381
-
Axl, a novel receptor tyrosine kinase isolated from chronic myelogenous leukemia
-
Neubauer A, O'Bryan JP, Fiebeler A, Schmidt C, Huhn D, Liu ET. Axl, a novel receptor tyrosine kinase isolated from chronic myelogenous leukemia. Seminars in hematology. 1993; 30:34.
-
(1993)
Seminars in hematology
, vol.30
, pp. 34
-
-
Neubauer, A.1
O'Bryan, J.P.2
Fiebeler, A.3
Schmidt, C.4
Huhn, D.5
Liu, E.T.6
-
62
-
-
33644876133
-
Expression of axl in lung adenocarcinoma and correlation with tumor progression
-
Shieh YS, Lai CY, Kao YR, Shiah SG, Chu YW, Lee HS, Wu CW. Expression of axl in lung adenocarcinoma and correlation with tumor progression. Neoplasia. 2005; 7:1058-1064.
-
(2005)
Neoplasia
, vol.7
, pp. 1058-1064
-
-
Shieh, Y.S.1
Lai, C.Y.2
Kao, Y.R.3
Shiah, S.G.4
Chu, Y.W.5
Lee, H.S.6
Wu, C.W.7
-
63
-
-
0036321937
-
Clinical significance of AXL kinase family in gastric cancer
-
Wu CW, Li AF, Chi CW, Lai CH, Huang CL, Lo SS, Lui WY, Lin WC. Clinical significance of AXL kinase family in gastric cancer. Anticancer research. 2002; 22:1071-1078.
-
(2002)
Anticancer research
, vol.22
, pp. 1071-1078
-
-
Wu, C.W.1
Li, A.F.2
Chi, C.W.3
Lai, C.H.4
Huang, C.L.5
Lo, S.S.6
Lui, W.Y.7
Lin, W.C.8
-
64
-
-
84871971116
-
ABL regulation by AXL promotes cisplatin resistance in esophageal cancer
-
Hong J, Peng D, Chen Z, Sehdev V, Belkhiri A. ABL regulation by AXL promotes cisplatin resistance in esophageal cancer. Cancer research. 2013; 73:331-340.
-
(2013)
Cancer research
, vol.73
, pp. 331-340
-
-
Hong, J.1
Peng, D.2
Chen, Z.3
Sehdev, V.4
Belkhiri, A.5
-
65
-
-
78549245919
-
The Axl receptor tyrosine kinase is an adverse prognostic factor and a therapeutic target in esophageal adenocarcinoma
-
Hector A, Montgomery EA, Karikari C, Canto M, Dunbar KB, Wang JS, Feldmann G, Hong SM, Haffner MC, Meeker AK, Holland SJ, Yu J, Heckrodt TJ, Zhang J, Ding P, Goff D, et al. The Axl receptor tyrosine kinase is an adverse prognostic factor and a therapeutic target in esophageal adenocarcinoma. Cancer biology & therapy. 2010; 10:1009-1018.
-
(2010)
Cancer biology & therapy
, vol.10
, pp. 1009-1018
-
-
Hector, A.1
Montgomery, E.A.2
Karikari, C.3
Canto, M.4
Dunbar, K.B.5
Wang, J.S.6
Feldmann, G.7
Hong, S.M.8
Haffner, M.C.9
Meeker, A.K.10
Holland, S.J.11
Yu, J.12
Heckrodt, T.J.13
Zhang, J.14
Ding, P.15
Goff, D.16
-
66
-
-
75749115996
-
Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival
-
Gjerdrum C, Tiron C, Hoiby T, Stefansson I, Haugen H, Sandal T, Collett K, Li S, McCormack E, Gjertsen BT, Micklem DR, Akslen LA, Glackin C, Lorens JB. Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival. Proceedings of the National Academy of Sciences of the United States of America. 2010; 107:1124-1129.
-
(2010)
Proceedings of the National Academy of Sciences of the United States of America
, vol.107
, pp. 1124-1129
-
-
Gjerdrum, C.1
Tiron, C.2
Hoiby, T.3
Stefansson, I.4
Haugen, H.5
Sandal, T.6
Collett, K.7
Li, S.8
McCormack, E.9
Gjertsen, B.T.10
Micklem, D.R.11
Akslen, L.A.12
Glackin, C.13
Lorens, J.B.14
-
67
-
-
84878982950
-
Gas6/Axl mediates tumor cell apoptosis, migration and invasion and predicts the clinical outcome of osteosarcoma patients
-
Han J, Tian R, Yong B, Luo C, Tan P, Shen J, Peng T. Gas6/Axl mediates tumor cell apoptosis, migration and invasion and predicts the clinical outcome of osteosarcoma patients. Biochemical and biophysical research communications. 2013; 435:493-500.
-
(2013)
Biochemical and biophysical research communications
, vol.435
, pp. 493-500
-
-
Han, J.1
Tian, R.2
Yong, B.3
Luo, C.4
Tan, P.5
Shen, J.6
Peng, T.7
-
68
-
-
76749123429
-
R428, a selective small molecule inhibitor of Axl kinase, blocks tumor spread and prolongs survival in models of metastatic breast cancer
-
Holland SJ, Pan A, Franci C, Hu Y, Chang B, Li W, Duan M, Torneros A, Yu J, Heckrodt TJ, Zhang J, Ding P, Apatira A, Chua J, Brandt R, Pine P, et al. R428, a selective small molecule inhibitor of Axl kinase, blocks tumor spread and prolongs survival in models of metastatic breast cancer. Cancer research. 2010; 70:1544-1554.
-
(2010)
Cancer research
, vol.70
, pp. 1544-1554
-
-
Holland, S.J.1
Pan, A.2
Franci, C.3
Hu, Y.4
Chang, B.5
Li, W.6
Duan, M.7
Torneros, A.8
Yu, J.9
Heckrodt, T.J.10
Zhang, J.11
Ding, P.12
Apatira, A.13
Chua, J.14
Brandt, R.15
Pine, P.16
-
69
-
-
70349705633
-
Axl as a potential therapeutic target in cancer: role of Axl in tumor growth, metastasis and angiogenesis
-
Li Y, Ye X, Tan C, Hongo JA, Zha J, Liu J, Kallop D, Ludlam MJ, Pei L. Axl as a potential therapeutic target in cancer: role of Axl in tumor growth, metastasis and angiogenesis. Oncogene. 2009; 28:3442-3455.
-
(2009)
Oncogene
, vol.28
, pp. 3442-3455
-
-
Li, Y.1
Ye, X.2
Tan, C.3
Hongo, J.A.4
Zha, J.5
Liu, J.6
Kallop, D.7
Ludlam, M.J.8
Pei, L.9
-
70
-
-
84892438921
-
First Axl inhibitor enters clinical trials
-
Sheridan C. First Axl inhibitor enters clinical trials. Nature biotechnology. 2013; 31:775-776.
-
(2013)
Nature biotechnology
, vol.31
, pp. 775-776
-
-
Sheridan, C.1
-
71
-
-
84881426249
-
Paradoxical role of the proto-oncogene Axl and Mer receptor tyrosine kinases in colon cancer
-
Bosurgi L, Bernink JH, Delgado Cuevas V, Gagliani N, Joannas L, Schmid ET, Booth CJ, Ghosh S, Rothlin CV. Paradoxical role of the proto-oncogene Axl and Mer receptor tyrosine kinases in colon cancer. Proceedings of the National Academy of Sciences of the United States of America. 2013; 110:13091-13096.
-
(2013)
Proceedings of the National Academy of Sciences of the United States of America
, vol.110
, pp. 13091-13096
-
-
Bosurgi, L.1
Bernink, J.H.2
Delgado Cuevas, V.3
Gagliani, N.4
Joannas, L.5
Schmid, E.T.6
Booth, C.J.7
Ghosh, S.8
Rothlin, C.V.9
-
72
-
-
84864402225
-
Activation of the AXL kinase causes resistance to EGFRtargeted therapy in lung cancer
-
Zhang Z, Lee JC, Lin L, Olivas V, Au V, LaFramboise T, Abdel-Rahman M, Wang X, Levine AD, Rho JK, Choi YJ, Choi CM, Kim SW, Jang SJ, Park YS, Kim WS, et al. Activation of the AXL kinase causes resistance to EGFRtargeted therapy in lung cancer. Nature genetics. 2012; 44:852-860.
-
(2012)
Nature genetics
, vol.44
, pp. 852-860
-
-
Zhang, Z.1
Lee, J.C.2
Lin, L.3
Olivas, V.4
Au, V.5
LaFramboise, T.6
Abdel-Rahman, M.7
Wang, X.8
Levine, A.D.9
Rho, J.K.10
Choi, Y.J.11
Choi, C.M.12
Kim, S.W.13
Jang, S.J.14
Park, Y.S.15
Kim, W.S.16
-
73
-
-
84880922644
-
Mer or Axl receptor tyrosine kinase inhibition promotes apoptosis, blocks growth and enhances chemosensitivity of human non-small cell lung cancer
-
Linger RM, Cohen RA, Cummings CT, Sather S, Migdall-Wilson J, Middleton DH, Lu X, Baron AE, Franklin WA, Merrick DT, Jedlicka P, DeRyckere D, Heasley LE, Graham DK. Mer or Axl receptor tyrosine kinase inhibition promotes apoptosis, blocks growth and enhances chemosensitivity of human non-small cell lung cancer. Oncogene. 2013; 32:3420-3431.
-
(2013)
Oncogene
, vol.32
, pp. 3420-3431
-
-
Linger, R.M.1
Cohen, R.A.2
Cummings, C.T.3
Sather, S.4
Migdall-Wilson, J.5
Middleton, D.H.6
Lu, X.7
Baron, A.E.8
Franklin, W.A.9
Merrick, D.T.10
Jedlicka, P.11
DeRyckere, D.12
Heasley, L.E.13
Graham, D.K.14
-
74
-
-
34948901399
-
Aurora-A: the maker and breaker of spindle poles
-
Barr AR, Gergely F. Aurora-A: the maker and breaker of spindle poles. Journal of cell science. 2007; 120:2987-2996.
-
(2007)
Journal of cell science
, vol.120
, pp. 2987-2996
-
-
Barr, A.R.1
Gergely, F.2
-
75
-
-
53349142277
-
Gains and amplifications of c-myc, EGFR, and 20.q13 loci in the no dysplasia-dysplasia-adenocarcinoma sequence of Barrett's esophagus
-
Rygiel AM, Milano F, Ten Kate FJ, Schaap A, Wang KK, Peppelenbosch MP, Bergman JJ, Krishnadath KK. Gains and amplifications of c-myc, EGFR, and 20.q13 loci in the no dysplasia-dysplasia-adenocarcinoma sequence of Barrett's esophagus. Cancer epidemiology, biomarkers & prevention: a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2008; 17:1380-1385.
-
(2008)
Cancer epidemiology, biomarkers & prevention: a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
, vol.17
, pp. 1380-1385
-
-
Rygiel, A.M.1
Milano, F.2
Ten Kate, F.J.3
Schaap, A.4
Wang, K.K.5
Peppelenbosch, M.P.6
Bergman, J.J.7
Krishnadath, K.K.8
-
76
-
-
0034660868
-
DNA sequence copy number changes in gastrointestinal stromal tumors: tumor progression and prognostic significance
-
El-Rifai W, Sarlomo-Rikala M, Andersson LC, Knuutila S, Miettinen M. DNA sequence copy number changes in gastrointestinal stromal tumors: tumor progression and prognostic significance. Cancer research. 2000; 60:3899-3903.
-
(2000)
Cancer research
, vol.60
, pp. 3899-3903
-
-
El-Rifai, W.1
Sarlomo-Rikala, M.2
Andersson, L.C.3
Knuutila, S.4
Miettinen, M.5
-
77
-
-
17744384260
-
Tumour-amplified kinase BTAK is amplified and overexpressed in gastric cancers with possible involvement in aneuploid formation
-
Sakakura C, Hagiwara A, Yasuoka R, Fujita Y, Nakanishi M, Masuda K, Shimomura K, Nakamura Y, Inazawa J, Abe T, Yamagishi H. Tumour-amplified kinase BTAK is amplified and overexpressed in gastric cancers with possible involvement in aneuploid formation. British journal of cancer. 2001; 84:824-831.
-
(2001)
British journal of cancer
, vol.84
, pp. 824-831
-
-
Sakakura, C.1
Hagiwara, A.2
Yasuoka, R.3
Fujita, Y.4
Nakanishi, M.5
Masuda, K.6
Shimomura, K.7
Nakamura, Y.8
Inazawa, J.9
Abe, T.10
Yamagishi, H.11
-
78
-
-
8444220396
-
Overexpression of Aurora-A contributes to malignant development of human esophageal squamous cell carcinoma
-
Tong T, Zhong Y, Kong J, Dong L, Song Y, Fu M, Liu Z, Wang M, Guo L, Lu S, Wu M, Zhan Q. Overexpression of Aurora-A contributes to malignant development of human esophageal squamous cell carcinoma. Clinical cancer research: an official journal of the American Association for Cancer Research. 2004; 10:7304-7310.
-
(2004)
Clinical cancer research: an official journal of the American Association for Cancer Research
, vol.10
, pp. 7304-7310
-
-
Tong, T.1
Zhong, Y.2
Kong, J.3
Dong, L.4
Song, Y.5
Fu, M.6
Liu, Z.7
Wang, M.8
Guo, L.9
Lu, S.10
Wu, M.11
Zhan, Q.12
-
80
-
-
0031714080
-
Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation
-
Zhou H, Kuang J, Zhong L, Kuo WL, Gray JW, Sahin A, Brinkley BR, Sen S. Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation. Nature genetics. 1998; 20:189-193.
-
(1998)
Nature genetics
, vol.20
, pp. 189-193
-
-
Zhou, H.1
Kuang, J.2
Zhong, L.3
Kuo, W.L.4
Gray, J.W.5
Sahin, A.6
Brinkley, B.R.7
Sen, S.8
-
81
-
-
9144251019
-
Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53
-
Katayama H, Sasai K, Kawai H, Yuan ZM, Bondaruk J, Suzuki F, Fujii S, Arlinghaus RB, Czerniak BA, Sen S. Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53. Nature genetics. 2004; 36:55-62.
-
(2004)
Nature genetics
, vol.36
, pp. 55-62
-
-
Katayama, H.1
Sasai, K.2
Kawai, H.3
Yuan, Z.M.4
Bondaruk, J.5
Suzuki, F.6
Fujii, S.7
Arlinghaus, R.B.8
Czerniak, B.A.9
Sen, S.10
-
82
-
-
10644227569
-
Aurora-A abrogation of p53 DNA binding and transactivation activity by phosphorylation of serine 215
-
Liu Q, Kaneko S, Yang L, Feldman RI, Nicosia SV, Chen J, Cheng JQ. Aurora-A abrogation of p53 DNA binding and transactivation activity by phosphorylation of serine 215. The Journal of biological chemistry. 2004; 279:52175-52182.
-
(2004)
The Journal of biological chemistry
, vol.279
, pp. 52175-52182
-
-
Liu, Q.1
Kaneko, S.2
Yang, L.3
Feldman, R.I.4
Nicosia, S.V.5
Chen, J.6
Cheng, J.Q.7
-
83
-
-
42149088289
-
Frequent overexpression of Aurora Kinase A in upper gastrointestinal adenocarcinomas correlates with potent antiapoptotic functions
-
Dar AA, Zaika A, Piazuelo MB, Correa P, Koyama T, Belkhiri A, Washington K, Castells A, Pera M, El-Rifai W. Frequent overexpression of Aurora Kinase A in upper gastrointestinal adenocarcinomas correlates with potent antiapoptotic functions. Cancer. 2008; 112:1688-1698.
-
(2008)
Cancer
, vol.112
, pp. 1688-1698
-
-
Dar, A.A.1
Zaika, A.2
Piazuelo, M.B.3
Correa, P.4
Koyama, T.5
Belkhiri, A.6
Washington, K.7
Castells, A.8
Pera, M.9
El-Rifai, W.10
-
84
-
-
55349124289
-
Aurora kinase A inhibition leads to p73-dependent apoptosis in p53-deficient cancer cells
-
Dar AA, Belkhiri A, Ecsedy J, Zaika A, El-Rifai W. Aurora kinase A inhibition leads to p73-dependent apoptosis in p53-deficient cancer cells. Cancer research. 2008; 68:8998-9004.
-
(2008)
Cancer research
, vol.68
, pp. 8998-9004
-
-
Dar, A.A.1
Belkhiri, A.2
Ecsedy, J.3
Zaika, A.4
El-Rifai, W.5
-
85
-
-
35948938922
-
Aurora-A, a negative prognostic marker, increases migration and decreases radiosensitivity in cancer cells
-
Guan Z, Wang XR, Zhu XF, Huang XF, Xu J, Wang LH, Wan XB, Long ZJ, Liu JN, Feng GK, Huang W, Zeng YX, Chen FJ, Liu Q. Aurora-A, a negative prognostic marker, increases migration and decreases radiosensitivity in cancer cells. Cancer research. 2007; 67:10436-10444.
-
(2007)
Cancer research
, vol.67
, pp. 10436-10444
-
-
Guan, Z.1
Wang, X.R.2
Zhu, X.F.3
Huang, X.F.4
Xu, J.5
Wang, L.H.6
Wan, X.B.7
Long, Z.J.8
Liu, J.N.9
Feng, G.K.10
Huang, W.11
Zeng, Y.X.12
Chen, F.J.13
Liu, Q.14
-
86
-
-
65649152925
-
Discovery and development of aurora kinase inhibitors as anticancer agents
-
Pollard JR, Mortimore M. Discovery and development of aurora kinase inhibitors as anticancer agents. Journal of medicinal chemistry. 2009; 52:2629-2651.
-
(2009)
Journal of medicinal chemistry
, vol.52
, pp. 2629-2651
-
-
Pollard, J.R.1
Mortimore, M.2
-
87
-
-
84873408412
-
The combination of alisertib, an investigational Aurora kinase A inhibitor, and docetaxel promotes cell death and reduces tumor growth in preclinical cell models of upper gastrointestinal adenocarcinomas
-
Sehdev V, Katsha A, Ecsedy J, Zaika A, Belkhiri A, El-Rifai W. The combination of alisertib, an investigational Aurora kinase A inhibitor, and docetaxel promotes cell death and reduces tumor growth in preclinical cell models of upper gastrointestinal adenocarcinomas. Cancer. 2013; 119:904-914.
-
(2013)
Cancer
, vol.119
, pp. 904-914
-
-
Sehdev, V.1
Katsha, A.2
Ecsedy, J.3
Zaika, A.4
Belkhiri, A.5
El-Rifai, W.6
-
88
-
-
84859405151
-
The aurora kinase A inhibitor MLN8237 enhances cisplatin-induced cell death in esophageal adenocarcinoma cells
-
Sehdev V, Peng D, Soutto M, Washington MK, Revetta F, Ecsedy J, Zaika A, Rau TT, Schneider-Stock R, Belkhiri A, El-Rifai W. The aurora kinase A inhibitor MLN8237 enhances cisplatin-induced cell death in esophageal adenocarcinoma cells. Molecular cancer therapeutics. 2012; 11:763-774.
-
(2012)
Molecular cancer therapeutics
, vol.11
, pp. 763-774
-
-
Sehdev, V.1
Peng, D.2
Soutto, M.3
Washington, M.K.4
Revetta, F.5
Ecsedy, J.6
Zaika, A.7
Rau, T.T.8
Schneider-Stock, R.9
Belkhiri, A.10
El-Rifai, W.11
-
89
-
-
84892159539
-
HDM2 Regulation by AURKA Promotes Cell Survival in Gastric Cancer
-
Sehdev V, Katsha A, Arras J, Peng D, Soutto M, Ecsedy J, Zaika A, Belkhiri A, El-Rifai W. HDM2 Regulation by AURKA Promotes Cell Survival in Gastric Cancer. Clinical cancer research: an official journal of the American Association for Cancer Research. 2014; 20:76-86.
-
(2014)
Clinical cancer research: an official journal of the American Association for Cancer Research
, vol.20
, pp. 76-86
-
-
Sehdev, V.1
Katsha, A.2
Arras, J.3
Peng, D.4
Soutto, M.5
Ecsedy, J.6
Zaika, A.7
Belkhiri, A.8
El-Rifai, W.9
-
90
-
-
84895922043
-
AXL induces epithelial-tomesenchymal transition and regulates the function of breast cancer stem cells
-
Asiedu MK, Beauchamp-Perez FD, Ingle JN, Behrens MD, Radisky DC, Knutson KL. AXL induces epithelial-tomesenchymal transition and regulates the function of breast cancer stem cells. Oncogene. 2014; 33:1316-1324.
-
(2014)
Oncogene
, vol.33
, pp. 1316-1324
-
-
Asiedu, M.K.1
Beauchamp-Perez, F.D.2
Ingle, J.N.3
Behrens, M.D.4
Radisky, D.C.5
Knutson, K.L.6
-
92
-
-
84888264541
-
Aurora kinase A promotes inflammation and tumorigenesis in mice and human gastric neoplasia
-
e1311-e1318
-
Katsha A, Soutto M, Sehdev V, Peng D, Washington MK, Piazuelo MB, Tantawy MN, Manning HC, Lu P, Shyr Y, Ecsedy J, Belkhiri A, El-Rifai W. Aurora kinase A promotes inflammation and tumorigenesis in mice and human gastric neoplasia. Gastroenterology. 2013; 145:1312-1322 e1311-1318.
-
(2013)
Gastroenterology
, vol.145
, pp. 1312-1322
-
-
Katsha, A.1
Soutto, M.2
Sehdev, V.3
Peng, D.4
Washington, M.K.5
Piazuelo, M.B.6
Tantawy, M.N.7
Manning, H.C.8
Lu, P.9
Shyr, Y.10
Ecsedy, J.11
Belkhiri, A.12
El-Rifai, W.13
|