A nuclear magnetic resonance method for probing molecular influences of substrate loading in nonribosomal peptide synthetase carrier proteins

Biochemistry

Volumn 54, Issue 5, 2015, Pages 1154-1156

  Goodrich, Andrew C ^a   Frueh, Dominique P ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROLYSIS; MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PEPTIDES; PROTEINS; SUBSTRATES;

COVALENT ATTACHMENT; MOLECULAR COMMUNICATION; MOLECULAR PROPERTIES; NONRIBOSOMAL PEPTIDE SYNTHETASES; SPECTROSCOPIC SIGNATURES; STRUCTURAL STUDIES; SUBSTRATE HYDROLYSIS; SUBSTRATE LOADING;

LOADING;

CARRIER PROTEIN; NONRIBOSOMAL PEPTIDE SYNTHETASE; YERSINIABACTIN; ESCHERICHIA COLI PROTEIN; PEPTIDE SYNTHASE;

ARTICLE; BINDING AFFINITY; CONFORMATIONAL TRANSITION; COVALENT BOND; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME SUBSTRATE; MOLECULAR PROBE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN HYDROLYSIS; PROTEIN PROTEIN INTERACTION; CHEMISTRY; ESCHERICHIA COLI; GENETICS; METABOLISM; NUCLEAR MAGNETIC RESONANCE;

CARRIER PROTEINS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PEPTIDE SYNTHASES;

EID: 84922668963     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi501433r     Document Type: Article

References (22)

1. Walsh, C. T. (2004) Science 303, 1805-1810
2. Stachelhaus, T., Schneider, A., and Marahiel, M. A. (1995) Science 269, 69-72
3. Frueh, D., Arthanari, H., Koglin, A., and Vosburg, D. (2008) Nature 454, 903-906
4. Tanovic, A., Samel, S. A., Essen, L.-O., and Marahiel, M. A. (2008) Science 321, 659-663
5. Koglin, A. 2006, Science 312, 273-276
6. Gulick, A. M. (2009) ACS Chem. Biol. 4, 811-827
7. Bloudoff, K., Rodionov, D., and Schmeing, T. M. (2013) J. Mol. Biol. 425, 3137-3150
8. Whicher, J. R. 2014, Nature 510, 560-564
9. Nguyen, C. 2014, Nature 505, 427-431
10. Gehring, A. M., Mori, I., Perry, R. D., and Walsh, C. T. (1998) Biochemistry 37, 11637-11650
11. Suo, Z., Walsh, C. T., and Miller, D. A. (1999) Biochemistry 38, 14023-14035
12. Schwarzer, D., Mootz, H. D., Linne, U., and Marahiel, M. A. (2002) Proc. Natl. Acad. Sci. U.S.A. 99, 14083-14088
13. Sattler, M. and Schleucher, J. (1999) Prog. Nucl. Magn. Reson. Spectrosc. 34, 93-158
14. Ferentz, A. E. and Wagner, G. (2002) Q. Rev. Biophys. 33, 29-65
15. Shen, Y., Delaglio, F., Cornilescu, G., and Bax, A. (2009) J. Biomol. NMR 44, 213-223
16. Wishart, D. and Sykes, B. (1994) J. Biomol. NMR 4, 171-180
17. Mayo, K. H. and Prestegard, J. H. (1985) Biochemistry 24, 7834-7838
18. Roujeinikova, A. 2002, Structure 10, 825-835
19. Płoskoń, E. 2010, Chem. Biol. 17, 776-785
20. Evans, S. E. 2009, J. Mol. Biol. 389, 511-528
21. Miller, D. A. and Walsh, C. T. (2001) Biochemistry 40, 5313-5321
22. Marshall, C. G., Burkart, M. D., Keating, T. A., and Walsh, C. T. (2001) Biochemistry 40, 10655-10663