Recognition of intermediate functionality by acyl carrier protein over a complete cycle of fatty acid biosynthesis

Chemistry and Biology

Volumn 17, Issue 7, 2010, Pages 776-785

  Płoskoń, Eliza ^a   Arthur, Christopher J ^a   Kanari, Amelia L P ^a   Wattana Amorn, Pakorn ^a   Williams, Christopher ^a   Crosby, John ^a   Simpson, Thomas J ^a   Willis, Christine L ^a   Crump, Matthew P ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

CHEMBIO

Indexed keywords

4'-PHOSPHOPANTETHEINE; ACYL CARRIER PROTEIN; BACTERIAL PROTEIN; DRUG DERIVATIVE; FATTY ACID; PANTETHEINE; PANTETHEINE PHOSPHATE;

AMINO ACID SEQUENCE; ARTICLE; BIOSYNTHESIS; CHEMICAL STRUCTURE; CHEMISTRY; HYDROPHOBICITY; METABOLISM; MOLECULAR GENETICS; PROTEIN CONFORMATION; STREPTOMYCES COELICOLOR; ANALOGS AND DERIVATIVES; CHEMICAL PHENOMENA;

ACYL CARRIER PROTEIN; AMINO ACID SEQUENCE; BACTERIAL PROTEINS; FATTY ACIDS; HYDROPHOBICITY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PANTETHEINE; PROTEIN CONFORMATION; STREPTOMYCES COELICOLOR; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS;

BACTERIA (MICROORGANISMS); STREPTOMYCES COELICOLOR;

EID: 77955463150     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2010.05.024     Document Type: Article

References (38)

1. C.J. Arthur , A.E. Szafranska , J. Long , J. Mills , R.J. Cox , S.C. Findlow , T.J. Simpson , M.P. Crump , and J. Crosby The malonyl transferase activity of type II polyketide synthase acyl carrier proteins Chem. Biol. 13 2006 587 596
2. C.J. Arthur , C. Williams , K. Pottage , E. Ploskon , S.C. Findlow , S.G. Burston , T.J. Simpson , M.P. Crump , and J. Crosby Structure and malonyl CoA-ACP transacylase binding of Streptomyces coelicolor fatty acid synthase acyl carrier protein ACS Chem. Biol. 4 2009 625 636
3. A. Breeze Isotope-filtered NMR methods for the study of biomolecular structure and interactions Prog. Nucl. Magn. Reson. Spectrosc. 36 2000 323 372
4. E.J. Brignole , S. Smith , and F.J. Asturias Conformational flexibility of metazoan fatty acid synthase enables catalysis Nat. Struct. Mol. Biol. 16 2009 190 197
5. D.M. Byers , and H. Gong Acyl carrier protein: structure-function relationships in a conserved multifunctional protein family Biochem. Cell Biol. 85 2007 649 662
6. D.I. Chan , T. Stockner , D.P. Tieleman , and H.J. Vogel Molecular dynamics simulations of the Apo-, Holo-, and acyl-forms of Escherichia coli acyl carrier protein J. Biol. Chem. 283 2008 33620 33629
7. F. Colizzi , M. Recanatini , and A. Cavalli Mechanical features of Plasmodium falciparum acyl carrier protein in the delivery of substrates J. Chem. Inf. Model. 48 2008 2289 2293
8. G. Cornilescu , F. Delaglio , and A. Bax Protein backbone angle restraints from searching a database for chemical shift and sequence homology J. Biomol. NMR 13 1999 289 302
9. R.J. Cox , T.S. Hitchman , K.J. Byrom , I.S. Findlow , J.A. Tanner , J. Crosby , and T.J. Simpson Post-translational modification of heterologously expressed Streptomyces type II polyketide synthase acyl carrier proteins FEBS Lett. 405 1997 267 272
10. F. Delaglio , S. Grzesiek , G.W. Vuister , G. Zhu , J. Pfeifer , and A. Bax NMRPipe: a multidimensional spectral processing system based on UNIX pipes J. Biomol. NMR 6 1995 277 293
11. S.E. Evans , C. Williams , C.J. Arthur , S.G. Burston , T.J. Simpson , J. Crosby , and M.P. Crump An ACP structural switch. Conformational differences between the apo and holo forms of the actinorhodin polyketide synthase acyl carrier protein ChemBioChem 9 2008 2424 2432
12. S.E. Evans , C. Williams , C.J. Arthur , E. Ploskon , P. Wattana-Amorn , R.J. Cox , J. Crosby , C.L. Willis , T.J. Simpson , and M.P. Crump Probing the interactions of early polyketide intermediates with the actinorhodin ACP from S. coelicolor A3(2) J. Mol. Biol. 389 2009 511 528
13. A.S. Flaman , J.M. Chen , S.C. Van Iderstine , and D.M. Byers Site-directed mutagenesis of acyl carrier protein (ACP) reveals amino acid residues involved in ACP structure and acyl-ACP synthetase activity J. Biol. Chem. 276 2001 35934 35939
14. A. Jerga , and C.O. Rock Acyl-acyl carrier protein regulates transcription of fatty acid biosynthetic genes via the FabT repressor in Streptococcus pneumoniae J. Biol. Chem. 284 2009 15364 15368
15. Y. Jia , W. Yuan , J. Wodzinska , C. Park , A.J. Sinskey , and J. Stubbe Mechanistic studies on class I polyhydroxybutyrate (PHB) synthase from Ralstonia eutropha: class I and III synthases share a similar catalytic mechanism Biochemistry 40 2001 1011 1019
16. Y. Kim , E.L. Kovrigin , and Z. Eletr NMR studies of Escherichia coli acyl carrier protein: dynamic and structural differences of the apo- and holo-forms Biochem. Biophys. Res. Commun. 341 2006 776 783
17. A. Koglin , M.R. Mofid , F. Löhr , B. Schäfer , V.V. Rogov , M.M. Blum , T. Mittag , M.A. Marahiel , F. Bernhard , and V. Dötsch Conformational switches modulate protein interactions in peptide antibiotic synthetases Science 312 2006 273 276
18. R.A. Laskowski , D.S. Moss , and J.M. Thornton Main-chain bond lengths and bond angles in protein structures J. Mol. Biol. 231 1993 1049 1067
19. J.P. Linge , S.I. O'Donoghue , and M. Nilges Automated assignment of ambiguous nuclear overhauser effects with ARIA Methods Enzymol. 339 2001 71 90
20. R.P. Massengo-Tiassé , and J.E. Cronan Diversity in enoyl-acyl carrier protein reductases Cell. Mol. Life Sci. 66 2009 1507 1517
21. A.D. McLachlan Rapid comparison of protein structures Acta Crystallogr. A 38 1982 871 873
22. A.J. Nederveen , J.F. Doreleijers , W. Vranken , Z. Miller , C.A. Spronk , S.B. Nabuurs , P. Güntert , M. Livny , J.L. Markley , and M. Nilges RECOORD: a recalculated coordinate database of 500+ proteins from the PDB using restraints from the BioMagResBank Proteins 59 2005 662 672
23. M. Nilges , M.J. Macias , S.I. O'Donoghue , and H. Oschkinat Automated NOESY interpretation with ambiguous distance restraints: the refined NMR solution structure of the pleckstrin homology domain from beta-spectrin J. Mol. Biol. 269 1997 408 422
24. M. Pellecchia , P. Sebbel , U. Hermanns , K. Wüthrich , and R. Glockshuber Pilus chaperone FimC-adhesin FimH interactions mapped by TROSY-NMR Nat. Struct. Biol. 6 1999 336 339
25. R.D. Peterson , C.A. Theimer , H. Wu , and J. Feigon New applications of 2D filtered/edited NOESY for assignment and structure elucidation of RNA and RNA-protein complexes J. Biomol. NMR 28 2004 59 67
26. E. Płoskoń , C.J. Arthur , S.E. Evans , C. Williams , J. Crosby , T.J. Simpson , and M.P. Crump A mammalian type I fatty acid synthase acyl carrier protein domain does not sequester acyl chains J. Biol. Chem. 283 2008 518 528
27. J.T. Rasmussen , T. Borchers , and J. Knudsen Comparison of the binding affinities of acyl-CoA-binding protein and fatty-acid-binding protein for long-chain acyl-CoA esters Biochem. J. 265 1990 849 855 (Pubitemid 20053891)
28. A. Roujeinikova , W.J. Simon , J. Gilroy , D.W. Rice , J.B. Rafferty , and A.R. Slabas Structural studies of fatty acyl-(acyl carrier protein) thioesters reveal a hydrophobic binding cavity that can expand to fit longer substrates J. Mol. Biol. 365 2007 135 145
29. S.K. Upadhyay , A. Misra , R. Srivastava , N. Surolia , A. Surolia , and M. Sundd Structural insights into the acyl intermediates of the Plasmodium falciparum fatty acid synthesis pathway: the mechanism of expansion of the acyl carrier protein core J. Biol. Chem. 284 2009 22390 22400
30. W.F. Vranken , W. Boucher , T.J. Stevens , R.H. Fogh , A. Pajon , M. Llinas , E.L. Ulrich , J.L. Markley , J. Ionides , and E.D. Laue The CCPN data model for NMR spectroscopy: development of a software pipeline Proteins 59 2005 687 696
31. G. Vriend WHAT IF: a molecular modeling and drug design program J. Mol. Graph. 8 1990 52 56 29
32. S.W. White , J. Zheng , Y.M. Zhang , and C.O. Rock The structural biology of type II fatty acid biosynthesis Annu. Rev. Biochem. 74 2005 791 831
33. R.L. Winston , and M.C. Fitzgerald Concentration and desalting of protein samples for mass spectrometry analysis Anal. Biochem. 262 1998 83 85
34. B.N. Wu , Y.M. Zhang , C.O. Rock , and J.J. Zheng Structural modification of acyl carrier protein by butyryl group Protein Sci. 18 2009 240 246
35. Y.M. Zhang , H. Marrakchi , S.W. White , and C.O. Rock The application of computational methods to explore the diversity and structure of bacterial fatty acid synthase J. Lipid Res. 44 2003 1 10
36. Y.M. Zhang , B. Wu , J. Zheng , and C.O. Rock Key residues responsible for acyl carrier protein and beta-ketoacyl-acyl carrier protein reductase (FabG) interaction J. Biol. Chem. 278 2003 52935 52943
37. G.A. Zornetzer , B.G. Fox , and J.L. Markley Solution structures of spinach acyl carrier protein with decanoate and stearate Biochemistry 45 2006 5217 5227
38. C. Zwahlen , P. Legault , S.J.F. Vincent , J. Greenblatt , R. Konrat , and L.E. Kay Methods for measurement of intermolecular NOEs by multinuclear NMR spectroscopy: Application to a bacteriophage lambda N-peptide/boxB RNA complex J. Am. Chem. Soc. 119 1997 6711 6721