Tandem heterocyclization activity of the multidomain 230 kDa HMWP2 subunit of Yersinia pestis yersiniabactin synthetase: Interaction of the 1- 1382 and 1383-2035 fragments

Biochemistry

Volumn 38, Issue 42, 1999, Pages 14023-14035

  Sou, Zucai ^a   Walsh, Christopher T ^a   Miller, Deborah Ann ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BACTERIA; CHEMICAL ACTIVATION; CHEMICAL OPERATIONS; CONDENSATION REACTIONS; ENZYME KINETICS; ESCHERICHIA COLI; MOLECULAR WEIGHT; PROTEINS; SOLUTIONS;

ADENYLATION; CYSKINYLATION; CYSTEINES; HETEROCYCLIZATION; HYDROXYPHENYLTHIAZOLINY; PHOSPHOPANTETHEINYLATED; SALICYLATE; YERSINIA PESTIS; YERSINIABACTIN SYNTHETASE;

ENZYMES;

BACTERIAL ENZYME; SIDEROPHORE; SYNTHETASE;

AMINO ACID SEQUENCE; ARTICLE; CYCLIZATION; ENZYME ACTIVITY; ENZYME MECHANISM; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; STRUCTURE ACTIVITY RELATION; YERSINIA PESTIS;

ACYL CARRIER PROTEIN; AMINO ACID SEQUENCE; BACTERIAL PROTEINS; CARRIER PROTEINS; CATALYSIS; CLONING, MOLECULAR; CYSTEINE; DITHIOTHREITOL; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PEPTIDE FRAGMENTS; PHENOLS; PROTEIN STRUCTURE, TERTIARY; SIDEROPHORES; SUBSTRATE SPECIFICITY; SULFHYDRYL COMPOUNDS; THIAZOLES; YERSINIA PESTIS;

EID: 0344761973     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi991574n     Document Type: Article

References (28)

1. Drechsel, H., Stephan, H., Lotz, R., Haag, H., Zähner, H., Hantke, K., and Jung, G. (1995) Liebigs Ann. Chem. 1995, 1727-1733.
2. Chambers, C. E., McIntyre, D. D., Mouck, M., and Sokol, P. A. (1996) BioMetals 9, 157-167.
3. Jackson, S., and Burrows, T. W. (1956) Br. J. Exp. Pathol. 37, 577-583.
4. Perry, R. D., and Fetherston, J. D. (1997) Clin. Microbiol. Rev. 10, 35-66.
5. Bearden, S. W., Fetherston, J. D., and Perry, R. D. (1997) Infect. Immun. 65, 1659-1668.
6. Fetherston, J. D., Lillard, J. W., Jr., and Perry, R. D. (1995) J. Bacteriol. 177, 1824-1833.
7. Haag, H., Hantke, K., Drechsel, H., Stojiljkovic, I., Jung, G., and Zähner, H. (1993) J. Gen. Microbiol. 139, 2159-2165.
8. Chambers, C. E., and Sokol, P. A. (1994) J. Clin. Microbiol. 32, 32-39.
9. Guilvout, I., Mercereau-Puijalon, O., Bonnefoy, S., Pugsley, A. P., and Carniel, E. (1993) J. Bacteriol. 175, 5488-5504.
10. Pelludat, C., Rakin, A., Jacobi, C. A., Schubert, S., and Heesemann, J. (1998) J. Bacteriol. 180, 538-546.
11. Gehring, A. M., DeMoll, E., Fetherston, J. D., Mon, I., Mayhew, G. F., Blattner, F. R., Walsh, C. T., and Perry, R. D. (1998) Chem. Biol. 5, 573-586.
12. Donadio, S., Staver, M. J., McAlpine, J. B., Swanson, S. J., and Katz, L. (1991) Science 252, 675-679.
13. Marahiel, M. A., Stachelhaus, T., and Mootz, H. D. (1997) Chem. Rev. 97, 2651-2673.
14. Walsh, C. T., Liu, J., Rusnak, F., and Sakaitani, M. (1990) Chem. Rev. 90, 1105-1129.
15. von Döhren, H., Keller, U., Vater, J., and Zocher, R. (1997) Chem. Rev. 97, 2675-2705.
16. Cox, C. D., Rinehart, K. L., Jr., Moore, M. L., and Cook, J. C., Jr. (1981) Proc. Natl. Acad. Sci. U.S.A. 78, 4256-4260.
17. Stubbe, J., and Kozarich, J. W. (1987) Chem. Rev. 87, 1107-1136.
18. Vanderwall, D. E., Lui, S. M., Wu, W., Turner, C. J., Kozarich, J. W., and Stubbe, J. (1997) Chem. Biol. 4, 373-387.
19. Gehring, A. M., Mori, I., Perry, R. D., and Walsh, C. T. (1998) Biochemistry 37, 11637-11650.
20. Konz, D., Kiens, A., Schörgendorfer, K., and Marahiel, M. A. (1997) Chem. Biol. 4, 927-937.
21. Quadi, L. E. N., Weinreb, P. H., Lei, M., Nakano, M. M.., Zuber, P., and Walsh, C. T. (1998) Biochemistry 37, 1585-1595.
22. Lambalot, R. H., Gehring, A. M., Flugel, R. S., Zuber, P., LaCelle, M., Marahiel, M. A., Reid, R., Khosla, C., and Walsh, C. T. (1996) Chem. Biol. 3, 923-936.
23. Gehring, A. M. (1998) Ph.D. Dissertation, Harvard Medical School, Boston, MA.
24. Ho, S. N., Hunt, H. D., Horton, R. M., Pullen, J. K., and Pease, L. R. (1989) Gene 77, 51-59.
25. Gehring, A. M., Bradley, K. A., and Walsh, C. T. (1997) Biochemistry 36, 8495-8503.
26. Gehring, A. M., Mori, I., and Walsh, C. T. (1998) Biochemistry 37, 2648-2659.
27. Kirley, T. L. (1989) Anal. Biochem. 180, 231-235.
28. Cane, D. E., Walsh, C. T., and Khosla, C. (1998) Science 282, 63-68.