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Volumn 59, Issue 1, 2012, Pages 1-5

Gpnmb/osteoactivin, an attractive target in cancer immunotherapy

Author keywords

Cancer immunotherapy; Glycoprotein non metastatic melanoma protein B; Osteoactivin

Indexed keywords

F6V; GELATINASE B; GLEMBATUMUMAB; GLEMBATUMUMAB VEDOTIN; GLYCOPROTEIN; MELANIN; MITOGEN ACTIVATED PROTEIN KINASE; OSTEOACTIVIN; PE38; STROMELYSIN; UNCLASSIFIED DRUG; ANTIBODY CONJUGATE; ANTINEOPLASTIC AGENT; GPNMB PROTEIN, HUMAN; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY; OLIGOPEPTIDE; TUMOR PROTEIN;

EID: 84863745351     PISSN: 00282685     EISSN: 13384317     Source Type: Journal    
DOI: 10.4149/neo_2012_001     Document Type: Review
Times cited : (51)

References (40)
  • 1
    • 33644747384 scopus 로고    scopus 로고
    • CR011, a fully human monoclonal antibody-auristatin E conjugate, for the treatment of melanoma
    • TSE KF, JEFFERS M, POLLACK VA, MCCABE DA, SHADISH ML et al. CR011, a fully human monoclonal antibody-auristatin E conjugate, for the treatment of melanoma. Clin Cancer Res 2006; 12: 1373-1382. http://dx.doi. org/10.1158/1078-0432.CCR-05-2018
    • (2006) Clin Cancer Res , vol.12 , pp. 1373-1382
    • Tse, K.F.1    Jeffers, M.2    Pollack, V.A.3    McCabe, D.A.4    Shadish, M.L.5
  • 2
    • 34248226374 scopus 로고    scopus 로고
    • Gpnmb is induced in macrophages by IFN-gamma and lipopolysaccharide and acts as a feedback regulator of proinflammatory responses
    • RIPOLL VM, IRVINE KM, RAVASI T, SWEET MJ, HUME DA Gpnmb is induced in macrophages by IFN-gamma and lipopolysaccharide and acts as a feedback regulator of proinflammatory responses. J Immunol 2007; 178: 6557-6566.
    • (2007) J Immunol , vol.178 , pp. 6557-6566
    • Ripoll, V.M.1    Irvine, K.M.2    Ravasi, T.3    Sweet, M.J.4    Hume, D.A.5
  • 3
    • 66949112599 scopus 로고    scopus 로고
    • Gpnmb is a melanosome-associated glycoprotein that contributes to melanocyte/keratinocyte adhesion in a RGD-dependent fashion
    • TOMIHARI M, HWANG SH, CHUNG JS, CRUZ PD JR, ARIIZUMI K Gpnmb is a melanosome-associated glycoprotein that contributes to melanocyte/keratinocyte adhesion in a RGD-dependent fashion. Exp Dermatol 2009; 18: 586-595. http://dx.doi.org/10.1111/j.1600-0625.2008.00830.x
    • (2009) Exp Dermatol , vol.18 , pp. 586-595
    • Tomihari, M.1    Hwang, S.H.2    Chung, J.S.3    Cruz Pd, J.R.4    Ariizumi, K.5
  • 4
    • 0038521296 scopus 로고    scopus 로고
    • Bone-related genes expressed in advanced malignancies induce invasion and metastasis in a genetically defined human cancer model
    • RICH JN, SHI Q, HJELMELAND M, CUMMINGS TJ, KUAN CT et al. Bone-related genes expressed in advanced malignancies induce invasion and metastasis in a genetically defined human cancer model. J Biol Chem 2003; 278: 15951-15957. http://dx.doi.org/10.1074/jbc.M211498200
    • (2003) J Biol Chem , vol.278 , pp. 15951-15957
    • Rich, J.N.1    Shi, Q.2    Hjelmeland, M.3    Cummings, T.J.4    Kuan, C.T.5
  • 5
    • 33646230317 scopus 로고    scopus 로고
    • Glycoprotein nonmetastatic melanoma protein B, a potential molecular therapeutic target in patients with glioblastoma multiforme
    • KUAN CT, WAKIYA K, DOWELL JM, HERNDON JE 2ND, REARDON DA et al. Glycoprotein nonmetastatic melanoma protein B, a potential molecular therapeutic target in patients with glioblastoma multiforme. Clin Cancer Res 2006; 12: 1970-1982. http://dx.doi.org/10.1158/1078-0432.CCR-05-2797
    • (2006) Clin Cancer Res , vol.12 , pp. 1970-1982
    • Kuan, C.T.1    Wakiya, K.2    Dowell, J.M.3    Herndon Ii, J.E.4    Reardon, D.A.5
  • 6
    • 35948930203 scopus 로고    scopus 로고
    • Osteoactivin promotes breast cancer metastasis to bone
    • ROSE AA, PEPIN F, RUSSO C, ABOU KHALIL JE, HALLETT M et al. Osteoactivin promotes breast cancer metastasis to bone. Mol Cancer Res 2007; 5: 1001-1014. http://dx.doi. org/10.1158/1541-7786.MCR-07-0119
    • (2007) Mol Cancer Res , vol.5 , pp. 1001-1014
    • Rose, A.A.1    Pepin, F.2    Russo, C.3    Abou Khalil, J.E.4    Hallett, M.5
  • 7
    • 0242690379 scopus 로고    scopus 로고
    • Osteoactivin expressed during cirrhosis development in rats fed a choline-deficient, L-amino acid-defined diet, accelerates motility of hepatoma cells
    • ONAGA M, IDO A, HASUIKE S, UTO H, MORIUCHI A et al. Osteoactivin expressed during cirrhosis development in rats fed a choline-deficient, L-amino acid-defined diet, accelerates motility of hepatoma cells. J Hepatol 2003; 39: 779-785. http://dx.doi.org/10.1016/S0168-8278(03)00361-1
    • (2003) J Hepatol , vol.39 , pp. 779-785
    • Onaga, M.1    Ido, A.2    Hasuike, S.3    Uto, H.4    Moriuchi, A.5
  • 8
    • 0035185649 scopus 로고    scopus 로고
    • Cloning and characterization of osteoactivin, a novel cDNA expressed in osteoblasts
    • SAFADI FF, XU J, SMOCK SL, RICO MC, OWEN TA et al. Cloning and characterization of osteoactivin, a novel cDNA expressed in osteoblasts. J Cell Biochem 2001; 84: 12-26.
    • (2001) J Cell Biochem , vol.84 , pp. 12-26
    • Safadi, F.F.1    Xu, J.2    Smock, S.L.3    Rico, M.C.4    Owen, T.A.5
  • 9
    • 0035896629 scopus 로고    scopus 로고
    • Molecular cloning of a dendritic cell-associated transmembrane protein, DC-HIL, that promotes RGD-dependent adhesion of endothelial cells through recognition of heparan sulfate proteoglycans
    • SHIKANO S, BONKOBARA M, ZUKAS PK, ARIIZUMI K Molecular cloning of a dendritic cell-associated transmembrane protein, DC-HIL, that promotes RGD-dependent adhesion of endothelial cells through recognition of heparan sulfate proteoglycans. J Biol Chem 2001; 276: 8125-8134. http://dx.doi.org/10.1074/jbc.M008539200
    • (2001) J Biol Chem , vol.276 , pp. 8125-8134
    • Shikano, S.1    Bonkobara, M.2    Zukas, P.K.3    Ariizumi, K.4
  • 12
    • 47349085102 scopus 로고    scopus 로고
    • Osteoactivin, an anabolic factor that regulates osteoblast differentiation and function
    • ABDELMAGID SM, BARBE MF, RICO MC, SALIHOGLU S, ARANGO-HISIJARA I et al. Osteoactivin, an anabolic factor that regulates osteoblast differentiation and function. Exp Cell Res 2008; 314: 2334-2351. http://dx.doi.org/10.1016/j.yexcr.2008.02.006
    • (2008) Exp Cell Res , vol.314 , pp. 2334-2351
    • Abdelmagid, S.M.1    Barbe, M.F.2    Rico, M.C.3    Salihoglu, S.4    Arango-Hisijara, I.5
  • 13
    • 41249095532 scopus 로고    scopus 로고
    • Microphthalmia transcription factor regulates the expression of the novel osteoclast factor GPNMB
    • RIPOLL VM, MEADOWS NA, RAGGATT LJ, CHANG MK, PETTIT AR et al. Microphthalmia transcription factor regulates the expression of the novel osteoclast factor GPNMB. Gene 2008; 413: 32-41. http://dx.doi.org/10.1016/j.gene.2008.01.014
    • (2008) Gene , vol.413 , pp. 32-41
    • Ripoll, V.M.1    Meadows, N.A.2    Raggatt, L.J.3    Chang, M.K.4    Pettit, A.R.5
  • 14
    • 42049100127 scopus 로고    scopus 로고
    • Osteoactivin is a novel osteoclastic protein and plays a key role in osteoclast differentiation and activity
    • SHENG MH, WERGEDAL JE, MOHAN S, LAU KH Osteoactivin is a novel osteoclastic protein and plays a key role in osteoclast differentiation and activity. FEBS Lett 2008; 582: 1451-1458. http://dx.doi.org/10.1016/j.febslet.2008.03.030
    • (2008) FEBS Lett , vol.582 , pp. 1451-1458
    • Sheng, M.H.1    Wergedal, J.E.2    Mohan, S.3    Lau, K.H.4
  • 15
    • 0036720825 scopus 로고    scopus 로고
    • Identification of the genes differentially expressed in human dendritic cell subsets by cDNA subtraction and microarray analysis
    • AHN JH, LEE Y, JEON C, LEE SJ, LEE BH et al. Identification of the genes differentially expressed in human dendritic cell subsets by cDNA subtraction and microarray analysis. Blood 2002; 100: 1742-1754.
    • (2002) Blood , vol.100 , pp. 1742-1754
    • Ahn, J.H.1    Lee, Y.2    Jeon, C.3    Lee, S.J.4    Lee, B.H.5
  • 16
    • 77952293797 scopus 로고    scopus 로고
    • Glycoprotein nonmetastatic melanoma protein b, a melanocytic cell marker, is a melanosome-specific and proteolytically released protein
    • HOASHI T, SATO S, YAMAGUCHI Y, PASSERON T, TAMAKI K et al. Glycoprotein nonmetastatic melanoma protein b, a melanocytic cell marker, is a melanosome-specific and proteolytically released protein. Faseb J 2010; 24: 1616-1629. http://dx.doi.org/10.1096/fj.09-151019
    • (2010) Faseb J , vol.24 , pp. 1616-1629
    • Hoashi, T.1    Sato, S.2    Yamaguchi, Y.3    Passeron, T.4    Tamaki, K.5
  • 17
    • 0346993732 scopus 로고    scopus 로고
    • Identification and characterization of the genes encoding human and mouse osteoactivin
    • OWEN TA, SMOCK SL, PRAKASH S, PINDER L, BREES D et al. Identification and characterization of the genes encoding human and mouse osteoactivin. Crit Rev Eukaryot Gene Expr 2003; 13: 205-220.
    • (2003) Crit Rev Eukaryot Gene Expr , vol.13 , pp. 205-220
    • Owen, T.A.1    Smock, S.L.2    Prakash, S.3    Pinder, L.4    Brees, D.5
  • 18
    • 0036334266 scopus 로고    scopus 로고
    • Mutations in genes encoding melanosomal proteins cause pigmentary glaucoma in DBA/2J mice
    • ANDERSON MG, SMITH RS, HAWES NL, ZABALETA A, CHANG B et al. Mutations in genes encoding melanosomal proteins cause pigmentary glaucoma in DBA/2J mice. Nat Genet 2002; 30: 81-85. http://dx.doi.org/10.1038/ng794
    • (2002) Nat Genet , vol.30 , pp. 81-85
    • Anderson, M.G.1    Smith, R.S.2    Hawes, N.L.3    Zabaleta, A.4    Chang, B.5
  • 19
    • 78649747024 scopus 로고    scopus 로고
    • The melanoma-associated transmembrane glycoprotein Gpnmb controls trafficking of cellular debris for degradation and is essential for tissue repair
    • LI B, CASTANO AP, HUDSON TE, NOWLIN BT, LIN SL et al. The melanoma-associated transmembrane glycoprotein Gpnmb controls trafficking of cellular debris for degradation and is essential for tissue repair. Faseb J 2010; 24: 4767-4781. http://dx.doi.org/10.1096/fj.10-154757
    • (2010) Faseb J , vol.24 , pp. 4767-4781
    • Li, B.1    Castano, A.P.2    Hudson, T.E.3    Nowlin, B.T.4    Lin, S.L.5
  • 20
    • 75749148813 scopus 로고    scopus 로고
    • Upregulation of monocyte/macrophage HGFIN (Gpnmb/Osteoactivin) expression in end-stage renal disease
    • PAHL MV, VAZIRI ND, YUAN J, ADLER SG Upregulation of monocyte/macrophage HGFIN (Gpnmb/Osteoactivin) expression in end-stage renal disease. Clin J Am Soc Nephrol 2010; 5: 56-61. http://dx.doi.org/10.2215/CJN.03390509
    • (2010) Clin J Am Soc Nephrol , vol.5 , pp. 56-61
    • Pahl, M.V.1    Vaziri, N.D.2    Yuan, J.3    Adler, S.G.4
  • 21
    • 34547794622 scopus 로고    scopus 로고
    • Early induction of osteoactivin expression in rat renal tubular epithelial cells after unilateral ureteral obstruction
    • NAKAMURA A, ISHII A, OHATA C, KOMURASAKI T Early induction of osteoactivin expression in rat renal tubular epithelial cells after unilateral ureteral obstruction. Exp Toxicol Pathol 2007; 59: 53-59. http://dx.doi.org/10.1016/j.etp.2007.03.005
    • (2007) Exp Toxicol Pathol , vol.59 , pp. 53-59
    • Nakamura, A.1    Ishii, A.2    Ohata, C.3    Komurasaki, T.4
  • 22
    • 77950021301 scopus 로고    scopus 로고
    • Genome-wide expression profiling reveals new candidate genes associated with osteoarthritis
    • KARLSSON C, DEHNE T, LINDAHL A, BRITTBERG M, PRUSS A et al. Genome-wide expression profiling reveals new candidate genes associated with osteoarthritis. Osteoarthritis Cartilage 2010; 18: 581-592. http://dx.doi. org/10.1016/j.joca.2009.12.002
    • (2010) Osteoarthritis Cartilage , vol.18 , pp. 581-592
    • Karlsson, C.1    Dehne, T.2    Lindahl, A.3    Brittberg, M.4    Pruss, A.5
  • 24
    • 77950670628 scopus 로고    scopus 로고
    • Glycoprotein nonmetastatic B is an independent prognostic indicator of recurrence and a novel therapeutic target in breast cancer
    • ROSE AA, GROSSET AA, DONG Z, RUSSO C, MACDONALD PA et al. Glycoprotein nonmetastatic B is an independent prognostic indicator of recurrence and a novel therapeutic target in breast cancer. Clin Cancer Res 2010; 16: 2147-2156. http://dx.doi.org/10.1158/1078-0432.CCR-09-1611
    • (2010) Clin Cancer Res , vol.16 , pp. 2147-2156
    • Rose, A.A.1    Grosset, A.A.2    Dong, Z.3    Russo, C.4    Macdonald, P.A.5
  • 25
    • 0028927442 scopus 로고
    • nmb, a novel gene, is expressed in low-metastatic human melanoma cell lines and xenografts
    • WETERMAN MA, AJUBI N, VAN DINTER IM, DEGEN WG, VAN MUIJEN GN et al. nmb, a novel gene, is expressed in low-metastatic human melanoma cell lines and xenografts. Int J Cancer 1995; 60: 73-81. http://dx.doi.org/10.1002/ijc.2910600111
    • (1995) Int J Cancer , vol.60 , pp. 73-81
    • Weterman, M.A.1    Ajubi, N.2    Van Dinter, I.M.3    Degen, W.G.4    Van Muijen, G.N.5
  • 26
    • 44649110229 scopus 로고    scopus 로고
    • Identification of novel vascular markers through gene expression profiling of tumor-derived endothelium
    • GHILARDI C, CHIORINO G, DOSSI R, NAGY Z, GIAVAZZI R et al. Identification of novel vascular markers through gene expression profiling of tumor-derived endothelium. BMC Genomics 2008; 9: 201. http://dx.doi.org/10.1186/1471-2164-9-201
    • (2008) BMC Genomics , vol.9 , pp. 201
    • Ghilardi, C.1    Chiorino, G.2    Dossi, R.3    Nagy, Z.4    Giavazzi, R.5
  • 27
    • 23944480317 scopus 로고    scopus 로고
    • Osteoactivin upregulates expression of MMP-3 and MMP-9 in fibroblasts infiltrated into denervated skeletal muscle in mice
    • OGAWA T, NIKAWA T, FUROCHI H, KOSYOJI M, HIRASAKA K et al. Osteoactivin upregulates expression of MMP-3 and MMP-9 in fibroblasts infiltrated into denervated skeletal muscle in mice. Am J Physiol Cell Physiol 2005; 289: C697-707. http://dx.doi.org/10.1152/ajpcell.00565.2004
    • (2005) Am J Physiol Cell Physiol , vol.289
    • Ogawa, T.1    Nikawa, T.2    Furochi, H.3    Kosyoji, M.4    Hirasaka, K.5
  • 28
    • 38449094315 scopus 로고    scopus 로고
    • Syndecan-4 mediates the coinhibitory function of DC-HIL on T cell activation
    • CHUNG JS, DOUGHERTY I, CRUZ PD JR, ARIIZUMI K Syndecan-4 mediates the coinhibitory function of DC-HIL on T cell activation. J Immunol 2007; 179: 5778-5784.
    • (2007) J Immunol , vol.179 , pp. 5778-5784
    • Chung, J.S.1    Dougherty, I.2    Cruz Pd, J.R.3    Ariizumi, K.4
  • 29
    • 34248368552 scopus 로고    scopus 로고
    • DC-HIL is a negative regulator of T lymphocyte activation
    • CHUNG JS, SATO K, DOUGHERTY II, CRUZ PD JR, ARIIZUMI K DC-HIL is a negative regulator of T lymphocyte activation. Blood 2007; 109: 4320-4327. http://dx.doi. org/10.1182/blood-2006-11-053769
    • (2007) Blood , vol.109 , pp. 4320-4327
    • Chung, J.S.1    Sato, K.2    Dougherty, I.I.3    Cruz Pd, J.R.4    Ariizumi, K.5
  • 30
    • 77954098750 scopus 로고    scopus 로고
    • Binding of DC-HIL to dermatophytic fungi induces tyrosine phosphorylation and potentiates antigen presenting cell function
    • CHUNG JS, YUDATE T, TOMIHARI M, AKIYOSHI H, CRUZ PD JR et al. Binding of DC-HIL to dermatophytic fungi induces tyrosine phosphorylation and potentiates antigen presenting cell function. J Immunol 2009; 183: 5190-5198. http://dx.doi.org/10.4049/jimmunol.0901319
    • (2009) J Immunol , vol.183 , pp. 5190-5198
    • Chung, J.S.1    Yudate, T.2    Tomihari, M.3    Akiyoshi, H.4    Cruz Pd, J.R.5
  • 31
    • 77955021117 scopus 로고    scopus 로고
    • DC-HIL/glycoprotein Nmb promotes growth of melanoma in mice by inhibiting the activation of tumorreactive T cells
    • TOMIHARI M, CHUNG JS, AKIYOSHI H, CRUZ PD JR, ARIIZUMI K DC-HIL/glycoprotein Nmb promotes growth of melanoma in mice by inhibiting the activation of tumorreactive T cells. Cancer Res 2010; 70: 5778-5787. http://dx.doi. org/10.1158/0008-5472.CAN-09-2538
    • (2010) Cancer Res , vol.70 , pp. 5778-5787
    • Tomihari, M.1    Chung, J.S.2    Akiyoshi, H.3    Cruz Pd, J.R.4    Ariizumi, K.5
  • 32
    • 65449138030 scopus 로고    scopus 로고
    • The DC-HIL/syndecan-4 pathway inhibits human allogeneic T-cell responses
    • CHUNG JS, BONKOBARA M, TOMIHARI M, CRUZ PD JR, ARIIZUMI K The DC-HIL/syndecan-4 pathway inhibits human allogeneic T-cell responses. Eur J Immunol 2009; 39: 965-974. http://dx.doi.org/10.1002/eji.200838990
    • (2009) Eur J Immunol , vol.39 , pp. 965-974
    • Chung, J.S.1    Bonkobara, M.2    Tomihari, M.3    Cruz Pd, J.R.4    Ariizumi, K.5
  • 33
    • 77957809884 scopus 로고    scopus 로고
    • ADAM10 releases a soluble form of the GPNMB/Osteoactivin extracellular domain with angiogenic properties
    • ROSE AA, ANNIS MG, DONG Z, PEPIN F, HALLETT M et al. ADAM10 releases a soluble form of the GPNMB/Osteoactivin extracellular domain with angiogenic properties. PLoS One 2010; 5: e12093. http://dx.doi.org/10.1371/journal. pone.0012093
    • (2010) PLoS One , vol.5
    • Rose, A.A.1    Annis, M.G.2    Dong, Z.3    Pepin, F.4    Hallett, M.5
  • 34
    • 14844324979 scopus 로고    scopus 로고
    • Expression of osteoactivin in rat and human liver and isolated rat liver cells
    • HARALANOVA-ILIEVA B, RAMADORI G, ARMBRUST T Expression of osteoactivin in rat and human liver and isolated rat liver cells. J Hepatol 2005; 42: 565-572. http://dx.doi. org/10.1016/j.jhep.2004.12.021
    • (2005) J Hepatol , vol.42 , pp. 565-572
    • Haralanova-Ilieva, B.1    Ramadori, G.2    Armbrust, T.3
  • 35
    • 49449119098 scopus 로고    scopus 로고
    • Antibody-drug conjugates for cancer therapy
    • CARTER PJ, SENTER PD Antibody-drug conjugates for cancer therapy. Cancer J 2008; 14: 154-169. http://dx.doi. org/10.1097/PPO.0b013e318172d704
    • (2008) Cancer J , vol.14 , pp. 154-169
    • Carter, P.J.1    Senter, P.D.2
  • 36
    • 34250613133 scopus 로고    scopus 로고
    • Treatment parameters modulating regression of human melanoma xenografts by an antibody-drug conjugate (CR011-vcMMAE) targeting GPNMB
    • POLLACK VA, ALVAREZ E, TSE KF, TORGOV MY, XIE S et al. Treatment parameters modulating regression of human melanoma xenografts by an antibody-drug conjugate (CR011-vcMMAE) targeting GPNMB. Cancer Chemother Pharmacol 2007; 60: 423-435. http://dx.doi.org/10.1007/s00280-007-0490-z
    • (2007) Cancer Chemother Pharmacol , vol.60 , pp. 423-435
    • Pollack, V.A.1    Alvarez, E.2    Tse, K.F.3    Torgov, M.Y.4    Xie, S.5
  • 37
    • 43649099521 scopus 로고    scopus 로고
    • Pharmacologically enhanced expression of GPNMB increases the sensitivity of melanoma cells to the CR011-vc-MMAE antibody-drug conjugate
    • QIAN X, MILLS E, TORGOV M, LAROCHELLE WJ, JEFFERS M Pharmacologically enhanced expression of GPNMB increases the sensitivity of melanoma cells to the CR011-vc-MMAE antibody-drug conjugate. Mol Oncol 2008; 2: 81-93. http://dx.doi.org/10.1016/j.molonc.2008.02.002
    • (2008) Mol Oncol , vol.2 , pp. 81-93
    • Qian, X.1    Mills, E.2    Torgov, M.3    Larochelle, W.J.4    Jeffers, M.5
  • 38
    • 79955406259 scopus 로고    scopus 로고
    • Affinity-matured anti-glycoprotein NMB recombinant immunotoxins targeting malignant gliomas and melanomas
    • KUAN CT, WAKIYA K, KEIR ST, LI J, HERNDON JE 2ND et al. Affinity-matured anti-glycoprotein NMB recombinant immunotoxins targeting malignant gliomas and melanomas. Int J Cancer 2011; 129: 111-121. http://dx.doi.org/10.1002/ijc.25645
    • (2011) Int J Cancer , vol.129 , pp. 111-121
    • Kuan, C.T.1    Wakiya, K.2    Keir, S.T.3    Li, J.4    Herndon Ii, J.E.5
  • 39
    • 33845417908 scopus 로고    scopus 로고
    • Osteoactivin acts as downstream mediator of BMP-2 effects on osteoblast function
    • ABDELMAGID SM, BARBE MF, ARANGO-HISIJARA I, OWEN TA, POPOFF SN et al. Osteoactivin acts as downstream mediator of BMP-2 effects on osteoblast function. J Cell Physiol 2007; 210: 26-37. http://dx.doi.org/10.1002/jcp.20841
    • (2007) J Cell Physiol , vol.210 , pp. 26-37
    • Abdelmagid, S.M.1    Barbe, M.F.2    Arango-Hisijara, I.3    Owen, T.A.4    Popoff, S.N.5


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