메뉴 건너뛰기




Volumn 51, Issue 2, 2015, Pages 158-163

AKT and MET signalling mediates antiapoptotic radioresistance in head neck cancer cell lines

Author keywords

AKT; ALDH; Apoptosis; Head neck cancer; Irradiation; MET; Stem cells

Indexed keywords

BCL2 RELATED PROTEIN A1; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; SCATTER FACTOR RECEPTOR; SURVIVIN;

EID: 84922641414     PISSN: 13688375     EISSN: 18790593     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2014.11.005     Document Type: Article
Times cited : (26)

References (46)
  • 3
    • 0036845442 scopus 로고    scopus 로고
    • Radiotherapy for cancer of the head and neck: Altered fractionation regimens
    • Nguyen LN, Ang KK. Radiotherapy for cancer of the head and neck: altered fractionation regimens. Lancet Oncol 2002;3:693-701.
    • (2002) Lancet Oncol , vol.3 , pp. 693-701
    • Nguyen, L.N.1    Ang, K.K.2
  • 6
    • 84872139491 scopus 로고    scopus 로고
    • ABT-737 reverses the acquired radioresistance of breast cancer cells by targeting Bcl-2 and Bcl-xL
    • Li J-Y, Li Y-Y, Jin W, Yang Q, Shao Z-M, Tian X-S. ABT-737 reverses the acquired radioresistance of breast cancer cells by targeting Bcl-2 and Bcl-xL. J Exp Clin Cancer Res 2012;31:102.
    • (2012) J Exp Clin Cancer Res , vol.31 , pp. 102
    • Li, J.-Y.1    Li, Y.-Y.2    Jin, W.3    Yang, Q.4    Shao, Z.-M.5    Tian, X.-S.6
  • 7
    • 33846807693 scopus 로고    scopus 로고
    • Overcoming the radioresistance of prostate cancer cells with a novel Bcl-2 inhibitor
    • An J, Chervin AS, Nie A, Ducoff HS, Huang Z. Overcoming the radioresistance of prostate cancer cells with a novel Bcl-2 inhibitor. Oncogene 2007;26:652-61.
    • (2007) Oncogene , vol.26 , pp. 652-661
    • An, J.1    Chervin, A.S.2    Nie, A.3    Ducoff H.S..4    Huang, Z.5
  • 8
    • 77955711901 scopus 로고    scopus 로고
    • Down-regulation of survivin by oxaliplatin diminishes radioresistance of head and neck squamous carcinoma cells
    • Khan Z, Khan N, Tiwari RP, Patro IK, Prasad GBKS, Bisen PS. Down-regulation of survivin by oxaliplatin diminishes radioresistance of head and neck squamous carcinoma cells. Radiother Oncol 2010;96:267-73.
    • (2010) Radiother Oncol , vol.96 , pp. 267-273
    • Khan, Z.1    Khan, N.2    Tiwari, R.P.3    Patro, I.K.4    Prasad, G.B.K.S.5    Bisen, P.S.6
  • 9
    • 84872139491 scopus 로고    scopus 로고
    • ABT-737 reverses the acquired radioresistance of breast cancer cells by targeting Bcl-2 and Bcl-xL
    • Li JY, Li YY, Jin W, Yang Q, Shao ZM, Tian XS. ABT-737 reverses the acquired radioresistance of breast cancer cells by targeting Bcl-2 and Bcl-xL. J Exp Clin Cancer Res: CR 2012;31:102.
    • (2012) J Exp Clin Cancer Res: CR , vol.31 , pp. 102
    • Li, J.Y.1    Li, Y.Y.2    Jin, W.3    Yang, Q.4    Shao, Z.M.5    Tian, X.S.6
  • 10
  • 11
    • 40749094856 scopus 로고    scopus 로고
    • Activation of the PI3-K/AKT pathway and implications for radioresistance mechanisms in head and neck cancer
    • Bussink J, van der Kogel AJ, Kaanders JH. Activation of the PI3-K/AKT pathway and implications for radioresistance mechanisms in head and neck cancer. Lancet Oncol 2008;9:288-96.
    • (2008) Lancet Oncol , vol.9 , pp. 288-296
    • Bussink, J.1    Van Der Kogel, A.J.2    Kaanders, J.H.3
  • 13
    • 73249143536 scopus 로고    scopus 로고
    • Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival
    • Bonner JA, Harari PM, Giralt J, Cohen RB, Jones CU, Sur RK, et al. Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival. Lancet Oncol 2010;11:21-8.
    • (2010) Lancet Oncol , vol.11 , pp. 21-28
    • Bonner, J.A.1    Harari, P.M.2    Giralt, J.3    Cohen, R.B.4    Jones, C.U.5    Sur, R.K.6
  • 14
    • 84905817727 scopus 로고    scopus 로고
    • Postoperative chemoradiotherapy and cetuximab for high-risk squamous cell carcinoma of the head and neck: Radiation therapy oncology group RTOG- 0234
    • Harari PM, Harris J, Kies MS, Myers JN, Jordan RC, Gillison ML, et al. Postoperative chemoradiotherapy and cetuximab for high-risk squamous cell carcinoma of the head and neck: radiation therapy oncology group RTOG- 0234. J Clin Oncol: Off J Am Soc Clin Oncol 2014;32:2486-95.
    • (2014) J Clin Oncol: Off J Am Soc Clin Oncol , vol.32 , pp. 2486-2495
    • Harari, P.M.1    Harris, J.2    Kies, M.S.3    Myers, J.N.4    Jordan, R.C.5    Gillison, M.L.6
  • 15
    • 84908268165 scopus 로고    scopus 로고
    • Phase II study of cetuximab in combination with cisplatin and radiation in unresectable, locally advanced head and neck squamous cell carcinoma: Eastern cooperative oncology group trial E3303
    • Egloff AM, Lee JW, Langer CJ, Quon H, Vaezi A, Grandis JR, et al. Phase II study of cetuximab in combination with cisplatin and radiation in unresectable, locally advanced head and neck squamous cell carcinoma: eastern cooperative oncology group trial E3303. Clin Cancer Res 2014;20:5041-51.
    • (2014) Clin Cancer Res , vol.20 , pp. 5041-5051
    • Egloff, A.M.1    Lee, J.W.2    Langer, C.J.3    Quon, H.4    Vaezi, A.5    Grandis, J.R.6
  • 16
  • 17
    • 84893845694 scopus 로고    scopus 로고
    • CMet expression is a marker of poor prognosis in patients with locally advanced head and neck squamous cell carcinoma treated with chemoradiation
    • Baschnagel AM, Williams L, Hanna A, Chen PY, Krauss DJ, Pruetz BL, et al. CMet expression is a marker of poor prognosis in patients with locally advanced head and neck squamous cell carcinoma treated with chemoradiation. Int J Radiat Oncol Biol Phys 2014;88:701-7.
    • (2014) Int J Radiat Oncol Biol Phys , vol.88 , pp. 701-707
    • Baschnagel, A.M.1    Williams, L.2    Hanna, A.3    Chen, P.Y.4    Krauss, D.J.5    Pruetz, B.L.6
  • 19
    • 84901791119 scopus 로고    scopus 로고
    • C-Met pathway promotes self-renewal and tumorigenecity of head and neck squamous cell carcinoma stem-like cell
    • Lim YC, Kang HJ, Moon JH. C-Met pathway promotes self-renewal and tumorigenecity of head and neck squamous cell carcinoma stem-like cell. Oral Oncol 2014;50:633-9.
    • (2014) Oral Oncol , vol.50 , pp. 633-639
    • Lim, Y.C.1    Kang, H.J.2    Moon, J.H.3
  • 20
    • 0024448596 scopus 로고
    • Biology, cytogenetics, and sensitivity to immunological effector cells of new head and neck squamous cell carcinoma lines
    • Heo DS, Snyderman C, Gollin SM, Pan S, Walker E, Deka R, et al. Biology, cytogenetics, and sensitivity to immunological effector cells of new head and neck squamous cell carcinoma lines. Cancer Res 1989;49:5167-75.
    • (1989) Cancer Res , vol.49 , pp. 5167-5175
    • Heo, D.S.1    Snyderman, C.2    Gollin, S.M.3    Pan, S.4    Walker, E.5    Deka, R.6
  • 22
    • 78449284621 scopus 로고    scopus 로고
    • Prognostic significance of survivin expression in renal cell cancer and its correlation with radioresistance
    • Lei Y, Geng Z, Guo-Jun W, He W, Jian-Lin Y. Prognostic significance of survivin expression in renal cell cancer and its correlation with radioresistance. Mol Cell Biochem 2010;344:23-31.
    • (2010) Mol Cell Biochem , vol.344 , pp. 23-31
    • Lei, Y.1    Geng, Z.2    Guo-Jun, W.3    He, W.4    Jian-Lin, Y.5
  • 24
    • 58149197153 scopus 로고    scopus 로고
    • Radiosensitizing effect of YM155, a novel small-molecule survivin suppressant, in non-small cell lung cancer cell lines
    • Iwasa T, Okamoto I, Suzuki M, Nakahara T, Yamanaka K, Hatashita E, et al. Radiosensitizing effect of YM155, a novel small-molecule survivin suppressant, in non-small cell lung cancer cell lines. Clin Cancer Res 2008;14:6496-504.
    • (2008) Clin Cancer Res , vol.14 , pp. 6496-6504
    • Iwasa, T.1    Okamoto, I.2    Suzuki, M.3    Nakahara, T.4    Yamanaka, K.5    Hatashita, E.6
  • 25
    • 23144464363 scopus 로고    scopus 로고
    • Transcriptional regulation and transformation by Myc proteins
    • Adhikary S, Eilers M. Transcriptional regulation and transformation by Myc proteins. Nat Rev Mol Cell Biol 2005:635-45.
    • (2005) Nat Rev Mol Cell Biol , pp. 635-645
    • Adhikary, S.1    Eilers, M.2
  • 26
    • 84862907711 scopus 로고    scopus 로고
    • C-Myc down-regulation is involved in proteasome inhibitormediated enhancement of radiotherapeutic efficacy in non-small cell lung cancer
    • Jeong S-Y. c-Myc down-regulation is involved in proteasome inhibitormediated enhancement of radiotherapeutic efficacy in non-small cell lung cancer. Int J Oncol 2012;40:385-90.
    • (2012) Int J Oncol , vol.40 , pp. 385-390
    • Jeong, S.-Y.1
  • 27
    • 0032442096 scopus 로고    scopus 로고
    • The proto-oncogene c-myc and apoptosis
    • Hoffman B, Liebermann DA. The proto-oncogene c-myc and apoptosis. Oncogene 1998;17:3351-7.
    • (1998) Oncogene , vol.17 , pp. 3351-3357
    • Hoffman, B.1    Liebermann, D.A.2
  • 30
    • 33747042839 scopus 로고    scopus 로고
    • Epidermal growth factor receptor and DNA double strand break repair: The cell's self-defence
    • Szumiel I. Epidermal growth factor receptor and DNA double strand break repair: the cell's self-defence. Cell Signal 2006:1537-48.
    • (2006) Cell Signal , pp. 1537-1548
    • Szumiel, I.1
  • 31
    • 28444475478 scopus 로고    scopus 로고
    • Radioresistance of K-Ras mutated human tumor cells is mediated through EGFR-dependent activation of PI3K-AKT pathway
    • Toulany M, Dittmann K, Krüger M, Baumann M, Rodemann HP. Radioresistance of K-Ras mutated human tumor cells is mediated through EGFR-dependent activation of PI3K-AKT pathway. Radiother Oncol 2005:143-50.
    • (2005) Radiother Oncol , pp. 143-150
    • Toulany, M.1    Dittmann, K.2    Krüger, M.3    Baumann, M.4    Rodemann, H.P.5
  • 34
    • 84862803141 scopus 로고    scopus 로고
    • Simultaneous inhibition of EGFR and PI3K enhances radiosensitivity in human breast cancer
    • Li P, Zhang Q, Torossian A, Li ZB, Xu WC, Lu B, et al. Simultaneous inhibition of EGFR and PI3K enhances radiosensitivity in human breast cancer. Int J Radiat Oncol Biol Phys 2012;83:e391-7.
    • (2012) Int J Radiat Oncol Biol Phys , vol.83 , pp. e391-e397
    • Li, P.1    Zhang, Q.2    Torossian, A.3    Li, Z.B.4    Xu, W.C.5    Lu, B.6
  • 35
    • 0033551070 scopus 로고    scopus 로고
    • New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway
    • Cantley LC, Neel BG. New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway. Proc Natl Acad Sci USA 1999;96:4240-5.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 4240-4245
    • Cantley, L.C.1    Neel, B.G.2
  • 36
    • 0033946740 scopus 로고    scopus 로고
    • Phosphorylation of the PTEN tail regulates protein stability and function
    • Vazquez F, Ramaswamy S, Nakamura N, Sellers WR. Phosphorylation of the PTEN tail regulates protein stability and function. Mol Cell Biol 2000;20:5010-8.
    • (2000) Mol Cell Biol , vol.20 , pp. 5010-5018
    • Vazquez, F.1    Ramaswamy, S.2    Nakamura, N.3    Sellers, W.R.4
  • 37
    • 84873123369 scopus 로고    scopus 로고
    • Reduced expression of PTEN and increased PTEN phosphorylation at residue Ser380 in gastric cancer tissues: A novel mechanism of PTEN inactivation
    • Yang Z, Yuan X-G, Chen J, Luo S-W, Luo Z-J, Lu N-H. Reduced expression of PTEN and increased PTEN phosphorylation at residue Ser380 in gastric cancer tissues: a novel mechanism of PTEN inactivation. Clin Res Hepatol Gastroenterol 2013;37:72-9.
    • (2013) Clin Res Hepatol Gastroenterol , vol.37 , pp. 72-79
    • Yang, Z.1    Yuan, X.-G.2    Chen, J.3    Luo, S.-W.4    Luo, Z.-J.5    Lu, N.-H.6
  • 38
    • 84861733799 scopus 로고    scopus 로고
    • MET: A promising anticancer therapeutic target
    • Peters S, Adjei AA. MET: a promising anticancer therapeutic target. Nat Rev Clin Oncol 2012;9:314-26.
    • (2012) Nat Rev Clin Oncol , vol.9 , pp. 314-326
    • Peters, S.1    Adjei, A.A.2
  • 39
    • 79955420135 scopus 로고    scopus 로고
    • Induction of MET by ionizing radiation and its role in radioresistance and invasive growth of cancer
    • Bacco Fd, Luraghi P, Medico E, Reato G, Girolami F, Perera T, et al. Induction of MET by ionizing radiation and its role in radioresistance and invasive growth of cancer. JNCI J Natl Cancer Inst 2011;103:645-61.
    • (2011) JNCI J Natl Cancer Inst , vol.103 , pp. 645-661
    • Fd, B.1    Luraghi, P.2    Medico, E.3    Reato, G.4    Girolami, F.5    Perera, T.6
  • 40
    • 0032537813 scopus 로고    scopus 로고
    • Scatter factor protects epithelial and carcinoma cells against apoptosis induced by DNA-damaging agents
    • Fan S, Wang JA, Yuan RQ, Rockwell S, Andres J, Zlatapolskiy A, et al. Scatter factor protects epithelial and carcinoma cells against apoptosis induced by DNA-damaging agents. Oncogene 1998;17:131-41.
    • (1998) Oncogene , vol.17 , pp. 131-141
    • Fan, S.1    Wang, J.A.2    Yuan, R.Q.3    Rockwell, S.4    Andres, J.5    Zlatapolskiy, A.6
  • 41
    • 80052971224 scopus 로고    scopus 로고
    • Head neck squamous cell carcinoma c-Met+ cells display cancer stem cell properties and are responsible for cisplatin-resistance and metastasis
    • Sun S, Wang Z. Head neck squamous cell carcinoma c-Met+ cells display cancer stem cell properties and are responsible for cisplatin-resistance and metastasis. Int J Cancer 2011;129:2337-48.
    • (2011) Int J Cancer , vol.129 , pp. 2337-2348
    • Sun, S.1    Wang, Z.2
  • 42
    • 79957846955 scopus 로고    scopus 로고
    • The PTEN/PI3K/Akt pathway regulates stem-like cells in primary esophageal carcinoma cells
    • Li H, Gao Q, Guo L, Lu SH. The PTEN/PI3K/Akt pathway regulates stem-like cells in primary esophageal carcinoma cells. Cancer Biol Ther 2011;11:950-8.
    • (2011) Cancer Biol Ther , vol.11 , pp. 950-958
    • Li, H.1    Gao, Q.2    Guo, L.3    Lu, S.H.4
  • 43
    • 36048963331 scopus 로고    scopus 로고
    • Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance
    • Zhou J, Wulfkuhle J, Zhang H, Gu P, Yang Y, Deng J, et al. Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance. Proc Natl Acad Sci USA 2007;104:16158-63.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 16158-16163
    • Zhou, J.1    Wulfkuhle, J.2    Zhang, H.3    Gu, P.4    Yang, Y.5    Deng, J.6
  • 44
    • 77954901231 scopus 로고    scopus 로고
    • Singlemarker identification of head and neck squamous cell carcinoma cancer stem cells with aldehyde dehydrogenase
    • Clay MR, Tabor M, Owen JH, Carey TE, Bradford CR, Wolf GT, et al. Singlemarker identification of head and neck squamous cell carcinoma cancer stem cells with aldehyde dehydrogenase. Head Neck 2010;32:1195-201.
    • (2010) Head Neck , vol.32 , pp. 1195-1201
    • Clay, M.R.1    Tabor, M.2    Owen, J.H.3    Carey, T.E.4    Bradford, C.R.5    Wolf, G.T.6
  • 45
    • 84927001056 scopus 로고    scopus 로고
    • Cancer stem-like cells from head and neck cancers are chemosensitized by the Wnt antagonist, sFRP4, by inducing apoptosis, decreasing stemness, drug resistance and epithelial to mesenchymal transition
    • Warrier S, Bhuvanalakshmi G, Arfuso F, Rajan G, Millward M, Dharmarajan A. Cancer stem-like cells from head and neck cancers are chemosensitized by the Wnt antagonist, sFRP4, by inducing apoptosis, decreasing stemness, drug resistance and epithelial to mesenchymal transition. Cancer Gene Ther 2014;21:381-8.
    • (2014) Cancer Gene Ther , vol.21 , pp. 381-388
    • Warrier, S.1    Bhuvanalakshmi, G.2    Arfuso, F.3    Rajan, G.4    Millward, M.5    Dharmarajan, A.6
  • 46
    • 84893797666 scopus 로고    scopus 로고
    • Targeting head and neck cancer stem cells to overcome resistance to photon and carbon ion radiation
    • Bertrand G, Maalouf M, Boivin A, Battiston-Montagne P, Beuve M, Levy A, et al. Targeting head and neck cancer stem cells to overcome resistance to photon and carbon ion radiation. Stem Cell Rev 2014;10:114-26.
    • (2014) Stem Cell Rev , vol.10 , pp. 114-126
    • Bertrand, G.1    Maalouf, M.2    Boivin, A.3    Battiston-Montagne, P.4    Beuve, M.5    Levy, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.