-
1
-
-
14944385553
-
Global cancer statistics, 2002
-
Parkin DM, Bray F, Ferlay J, Pisani P. Global cancer statistics, 2002. CA Cancer J Clin 2005;55:74-108.
-
(2005)
CA Cancer J Clin
, vol.55
, pp. 74-108
-
-
Parkin, D.M.1
Bray, F.2
Ferlay, J.3
Pisani, P.4
-
3
-
-
0036845442
-
Radiotherapy for cancer of the head and neck: Altered fractionation regimens
-
Nguyen LN, Ang KK. Radiotherapy for cancer of the head and neck: altered fractionation regimens. Lancet Oncol 2002;3:693-701.
-
(2002)
Lancet Oncol
, vol.3
, pp. 693-701
-
-
Nguyen, L.N.1
Ang, K.K.2
-
4
-
-
84864592088
-
Impact of intensity-modulated and image-guided radiotherapy on elderly patients undergoing chemoradiation for locally advanced head and neck cancer
-
Nguyen NP, Vock J, Chi A, Vinh-Hung V, Dutta S, Ewell L, et al. Impact of intensity-modulated and image-guided radiotherapy on elderly patients undergoing chemoradiation for locally advanced head and neck cancer. Strahlentherapie und Onkologie: Organ der Deutschen Rontgengesellschaft [et al.] 2012;188:677-83.
-
(2012)
Strahlentherapie und Onkologie: Organ der Deutschen Rontgengesellschaft [Et Al.]
, vol.188
, pp. 677-683
-
-
Nguyen, N.P.1
Vock, J.2
Chi, A.3
Vinh-Hung, V.4
Dutta, S.5
Ewell, L.6
-
6
-
-
84872139491
-
ABT-737 reverses the acquired radioresistance of breast cancer cells by targeting Bcl-2 and Bcl-xL
-
Li J-Y, Li Y-Y, Jin W, Yang Q, Shao Z-M, Tian X-S. ABT-737 reverses the acquired radioresistance of breast cancer cells by targeting Bcl-2 and Bcl-xL. J Exp Clin Cancer Res 2012;31:102.
-
(2012)
J Exp Clin Cancer Res
, vol.31
, pp. 102
-
-
Li, J.-Y.1
Li, Y.-Y.2
Jin, W.3
Yang, Q.4
Shao, Z.-M.5
Tian, X.-S.6
-
7
-
-
33846807693
-
Overcoming the radioresistance of prostate cancer cells with a novel Bcl-2 inhibitor
-
An J, Chervin AS, Nie A, Ducoff HS, Huang Z. Overcoming the radioresistance of prostate cancer cells with a novel Bcl-2 inhibitor. Oncogene 2007;26:652-61.
-
(2007)
Oncogene
, vol.26
, pp. 652-661
-
-
An, J.1
Chervin, A.S.2
Nie, A.3
Ducoff H.S..4
Huang, Z.5
-
8
-
-
77955711901
-
Down-regulation of survivin by oxaliplatin diminishes radioresistance of head and neck squamous carcinoma cells
-
Khan Z, Khan N, Tiwari RP, Patro IK, Prasad GBKS, Bisen PS. Down-regulation of survivin by oxaliplatin diminishes radioresistance of head and neck squamous carcinoma cells. Radiother Oncol 2010;96:267-73.
-
(2010)
Radiother Oncol
, vol.96
, pp. 267-273
-
-
Khan, Z.1
Khan, N.2
Tiwari, R.P.3
Patro, I.K.4
Prasad, G.B.K.S.5
Bisen, P.S.6
-
9
-
-
84872139491
-
ABT-737 reverses the acquired radioresistance of breast cancer cells by targeting Bcl-2 and Bcl-xL
-
Li JY, Li YY, Jin W, Yang Q, Shao ZM, Tian XS. ABT-737 reverses the acquired radioresistance of breast cancer cells by targeting Bcl-2 and Bcl-xL. J Exp Clin Cancer Res: CR 2012;31:102.
-
(2012)
J Exp Clin Cancer Res: CR
, vol.31
, pp. 102
-
-
Li, J.Y.1
Li, Y.Y.2
Jin, W.3
Yang, Q.4
Shao, Z.M.5
Tian, X.S.6
-
10
-
-
82555205497
-
Cancer stem cells: Targets and potential biomarkers for radiotherapy
-
Krause M, Yaromina A, Eicheler W, Koch U, Baumann M. Cancer stem cells: targets and potential biomarkers for radiotherapy. Clin Cancer Res 2011;17:7224-9.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 7224-7229
-
-
Krause, M.1
Yaromina, A.2
Eicheler, W.3
Koch, U.4
Baumann, M.5
-
11
-
-
40749094856
-
Activation of the PI3-K/AKT pathway and implications for radioresistance mechanisms in head and neck cancer
-
Bussink J, van der Kogel AJ, Kaanders JH. Activation of the PI3-K/AKT pathway and implications for radioresistance mechanisms in head and neck cancer. Lancet Oncol 2008;9:288-96.
-
(2008)
Lancet Oncol
, vol.9
, pp. 288-296
-
-
Bussink, J.1
Van Der Kogel, A.J.2
Kaanders, J.H.3
-
12
-
-
32144433159
-
Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck
-
Bonner JA, Harari PM, Giralt J, Azarnia N, Shin DM, Cohen RB, et al. Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N Engl J Med 2006;354:567-78.
-
(2006)
N Engl J Med
, vol.354
, pp. 567-578
-
-
Bonner, J.A.1
Harari, P.M.2
Giralt, J.3
Azarnia, N.4
Shin, D.M.5
Cohen, R.B.6
-
13
-
-
73249143536
-
Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival
-
Bonner JA, Harari PM, Giralt J, Cohen RB, Jones CU, Sur RK, et al. Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival. Lancet Oncol 2010;11:21-8.
-
(2010)
Lancet Oncol
, vol.11
, pp. 21-28
-
-
Bonner, J.A.1
Harari, P.M.2
Giralt, J.3
Cohen, R.B.4
Jones, C.U.5
Sur, R.K.6
-
14
-
-
84905817727
-
Postoperative chemoradiotherapy and cetuximab for high-risk squamous cell carcinoma of the head and neck: Radiation therapy oncology group RTOG- 0234
-
Harari PM, Harris J, Kies MS, Myers JN, Jordan RC, Gillison ML, et al. Postoperative chemoradiotherapy and cetuximab for high-risk squamous cell carcinoma of the head and neck: radiation therapy oncology group RTOG- 0234. J Clin Oncol: Off J Am Soc Clin Oncol 2014;32:2486-95.
-
(2014)
J Clin Oncol: Off J Am Soc Clin Oncol
, vol.32
, pp. 2486-2495
-
-
Harari, P.M.1
Harris, J.2
Kies, M.S.3
Myers, J.N.4
Jordan, R.C.5
Gillison, M.L.6
-
15
-
-
84908268165
-
Phase II study of cetuximab in combination with cisplatin and radiation in unresectable, locally advanced head and neck squamous cell carcinoma: Eastern cooperative oncology group trial E3303
-
Egloff AM, Lee JW, Langer CJ, Quon H, Vaezi A, Grandis JR, et al. Phase II study of cetuximab in combination with cisplatin and radiation in unresectable, locally advanced head and neck squamous cell carcinoma: eastern cooperative oncology group trial E3303. Clin Cancer Res 2014;20:5041-51.
-
(2014)
Clin Cancer Res
, vol.20
, pp. 5041-5051
-
-
Egloff, A.M.1
Lee, J.W.2
Langer, C.J.3
Quon, H.4
Vaezi, A.5
Grandis, J.R.6
-
16
-
-
84877578990
-
Modulation of c-Met signaling and cellular sensitivity to radiation
-
Bhardwaj V, Cascone T, Cortez MA, Amini A, Evans J, Komaki RU, et al. Modulation of c-Met signaling and cellular sensitivity to radiation. Cancer 2013;119:1768-75.
-
(2013)
Cancer
, vol.119
, pp. 1768-1775
-
-
Bhardwaj, V.1
Cascone, T.2
Cortez, M.A.3
Amini, A.4
Evans, J.5
Komaki, R.U.6
-
17
-
-
84893845694
-
CMet expression is a marker of poor prognosis in patients with locally advanced head and neck squamous cell carcinoma treated with chemoradiation
-
Baschnagel AM, Williams L, Hanna A, Chen PY, Krauss DJ, Pruetz BL, et al. CMet expression is a marker of poor prognosis in patients with locally advanced head and neck squamous cell carcinoma treated with chemoradiation. Int J Radiat Oncol Biol Phys 2014;88:701-7.
-
(2014)
Int J Radiat Oncol Biol Phys
, vol.88
, pp. 701-707
-
-
Baschnagel, A.M.1
Williams, L.2
Hanna, A.3
Chen, P.Y.4
Krauss, D.J.5
Pruetz, B.L.6
-
19
-
-
84901791119
-
C-Met pathway promotes self-renewal and tumorigenecity of head and neck squamous cell carcinoma stem-like cell
-
Lim YC, Kang HJ, Moon JH. C-Met pathway promotes self-renewal and tumorigenecity of head and neck squamous cell carcinoma stem-like cell. Oral Oncol 2014;50:633-9.
-
(2014)
Oral Oncol
, vol.50
, pp. 633-639
-
-
Lim, Y.C.1
Kang, H.J.2
Moon, J.H.3
-
20
-
-
0024448596
-
Biology, cytogenetics, and sensitivity to immunological effector cells of new head and neck squamous cell carcinoma lines
-
Heo DS, Snyderman C, Gollin SM, Pan S, Walker E, Deka R, et al. Biology, cytogenetics, and sensitivity to immunological effector cells of new head and neck squamous cell carcinoma lines. Cancer Res 1989;49:5167-75.
-
(1989)
Cancer Res
, vol.49
, pp. 5167-5175
-
-
Heo, D.S.1
Snyderman, C.2
Gollin, S.M.3
Pan, S.4
Walker, E.5
Deka, R.6
-
22
-
-
78449284621
-
Prognostic significance of survivin expression in renal cell cancer and its correlation with radioresistance
-
Lei Y, Geng Z, Guo-Jun W, He W, Jian-Lin Y. Prognostic significance of survivin expression in renal cell cancer and its correlation with radioresistance. Mol Cell Biochem 2010;344:23-31.
-
(2010)
Mol Cell Biochem
, vol.344
, pp. 23-31
-
-
Lei, Y.1
Geng, Z.2
Guo-Jun, W.3
He, W.4
Jian-Lin, Y.5
-
23
-
-
36248971578
-
The role of survivin for radiation therapy. Prognostic and predictive factor and therapeutic target
-
Capalbo G, Rodel C, Stauber RH, Knauer SK, Bache M, Kappler M, et al. The role of survivin for radiation therapy. Prognostic and predictive factor and therapeutic target. Strahlentherapie und Onkologie: Organ der Deutschen Rontgengesellschaft [et al.] 2007;183:593-9.
-
(2007)
Strahlentherapie und Onkologie: Organ der Deutschen Rontgengesellschaft [Et Al.]
, vol.183
, pp. 593-599
-
-
Capalbo, G.1
Rodel, C.2
Stauber, R.H.3
Knauer, S.K.4
Bache, M.5
Kappler, M.6
-
24
-
-
58149197153
-
Radiosensitizing effect of YM155, a novel small-molecule survivin suppressant, in non-small cell lung cancer cell lines
-
Iwasa T, Okamoto I, Suzuki M, Nakahara T, Yamanaka K, Hatashita E, et al. Radiosensitizing effect of YM155, a novel small-molecule survivin suppressant, in non-small cell lung cancer cell lines. Clin Cancer Res 2008;14:6496-504.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 6496-6504
-
-
Iwasa, T.1
Okamoto, I.2
Suzuki, M.3
Nakahara, T.4
Yamanaka, K.5
Hatashita, E.6
-
25
-
-
23144464363
-
Transcriptional regulation and transformation by Myc proteins
-
Adhikary S, Eilers M. Transcriptional regulation and transformation by Myc proteins. Nat Rev Mol Cell Biol 2005:635-45.
-
(2005)
Nat Rev Mol Cell Biol
, pp. 635-645
-
-
Adhikary, S.1
Eilers, M.2
-
26
-
-
84862907711
-
C-Myc down-regulation is involved in proteasome inhibitormediated enhancement of radiotherapeutic efficacy in non-small cell lung cancer
-
Jeong S-Y. c-Myc down-regulation is involved in proteasome inhibitormediated enhancement of radiotherapeutic efficacy in non-small cell lung cancer. Int J Oncol 2012;40:385-90.
-
(2012)
Int J Oncol
, vol.40
, pp. 385-390
-
-
Jeong, S.-Y.1
-
27
-
-
0032442096
-
The proto-oncogene c-myc and apoptosis
-
Hoffman B, Liebermann DA. The proto-oncogene c-myc and apoptosis. Oncogene 1998;17:3351-7.
-
(1998)
Oncogene
, vol.17
, pp. 3351-3357
-
-
Hoffman, B.1
Liebermann, D.A.2
-
28
-
-
33645084781
-
PIK3CA mutations in head and neck squamous cell carcinoma
-
Qiu W, Schönleben F, Li X, Ho DJ, Close LG, Manolidis S, et al. PIK3CA mutations in head and neck squamous cell carcinoma. Clin Cancer Res 2006:1441-6.
-
(2006)
Clin Cancer Res
, pp. 1441-1446
-
-
Qiu, W.1
Schönleben, F.2
Li, X.3
Ho, D.J.4
Close, L.G.5
Manolidis, S.6
-
29
-
-
1642471831
-
PI3K/Akt and apoptosis: Size matters
-
Franke TF, Hornik CP, Segev L, Shostak GA, Sugimoto C. PI3K/Akt and apoptosis: size matters. Oncogene 2003;22:8983-98.
-
(2003)
Oncogene
, vol.22
, pp. 8983-8998
-
-
Franke, T.F.1
Hornik, C.P.2
Segev, L.3
Shostak, G.A.4
Sugimoto, C.5
-
30
-
-
33747042839
-
Epidermal growth factor receptor and DNA double strand break repair: The cell's self-defence
-
Szumiel I. Epidermal growth factor receptor and DNA double strand break repair: the cell's self-defence. Cell Signal 2006:1537-48.
-
(2006)
Cell Signal
, pp. 1537-1548
-
-
Szumiel, I.1
-
31
-
-
28444475478
-
Radioresistance of K-Ras mutated human tumor cells is mediated through EGFR-dependent activation of PI3K-AKT pathway
-
Toulany M, Dittmann K, Krüger M, Baumann M, Rodemann HP. Radioresistance of K-Ras mutated human tumor cells is mediated through EGFR-dependent activation of PI3K-AKT pathway. Radiother Oncol 2005:143-50.
-
(2005)
Radiother Oncol
, pp. 143-150
-
-
Toulany, M.1
Dittmann, K.2
Krüger, M.3
Baumann, M.4
Rodemann, H.P.5
-
32
-
-
51649085865
-
Platinum-based chemotherapy plus cetuximab in head and neck cancer
-
Vermorken JB, Mesia R, Rivera F, Remenar E, Kawecki A, Rottey S, et al. Platinum-based chemotherapy plus cetuximab in head and neck cancer. N Engl J Med 2008;359:1116-27.
-
(2008)
N Engl J Med
, vol.359
, pp. 1116-1127
-
-
Vermorken, J.B.1
Mesia, R.2
Rivera, F.3
Remenar, E.4
Kawecki, A.5
Rottey, S.6
-
33
-
-
84929453705
-
MTOR co-targeting in cetuximab resistance in head and neck cancers harboring PIK3CA and RAS mutations
-
Wang Z, Martin D, Molinolo AA, Patel V, Iglesias-Bartolome R, Sol Degese M, et al. mTOR co-targeting in cetuximab resistance in head and neck cancers harboring PIK3CA and RAS mutations. J Natl Cancer Inst 2014;106.
-
(2014)
J Natl Cancer Inst
, vol.106
-
-
Wang, Z.1
Martin, D.2
Molinolo, A.A.3
Patel, V.4
Iglesias-Bartolome, R.5
Sol Degese, M.6
-
34
-
-
84862803141
-
Simultaneous inhibition of EGFR and PI3K enhances radiosensitivity in human breast cancer
-
Li P, Zhang Q, Torossian A, Li ZB, Xu WC, Lu B, et al. Simultaneous inhibition of EGFR and PI3K enhances radiosensitivity in human breast cancer. Int J Radiat Oncol Biol Phys 2012;83:e391-7.
-
(2012)
Int J Radiat Oncol Biol Phys
, vol.83
, pp. e391-e397
-
-
Li, P.1
Zhang, Q.2
Torossian, A.3
Li, Z.B.4
Xu, W.C.5
Lu, B.6
-
35
-
-
0033551070
-
New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway
-
Cantley LC, Neel BG. New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway. Proc Natl Acad Sci USA 1999;96:4240-5.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 4240-4245
-
-
Cantley, L.C.1
Neel, B.G.2
-
36
-
-
0033946740
-
Phosphorylation of the PTEN tail regulates protein stability and function
-
Vazquez F, Ramaswamy S, Nakamura N, Sellers WR. Phosphorylation of the PTEN tail regulates protein stability and function. Mol Cell Biol 2000;20:5010-8.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 5010-5018
-
-
Vazquez, F.1
Ramaswamy, S.2
Nakamura, N.3
Sellers, W.R.4
-
37
-
-
84873123369
-
Reduced expression of PTEN and increased PTEN phosphorylation at residue Ser380 in gastric cancer tissues: A novel mechanism of PTEN inactivation
-
Yang Z, Yuan X-G, Chen J, Luo S-W, Luo Z-J, Lu N-H. Reduced expression of PTEN and increased PTEN phosphorylation at residue Ser380 in gastric cancer tissues: a novel mechanism of PTEN inactivation. Clin Res Hepatol Gastroenterol 2013;37:72-9.
-
(2013)
Clin Res Hepatol Gastroenterol
, vol.37
, pp. 72-79
-
-
Yang, Z.1
Yuan, X.-G.2
Chen, J.3
Luo, S.-W.4
Luo, Z.-J.5
Lu, N.-H.6
-
38
-
-
84861733799
-
MET: A promising anticancer therapeutic target
-
Peters S, Adjei AA. MET: a promising anticancer therapeutic target. Nat Rev Clin Oncol 2012;9:314-26.
-
(2012)
Nat Rev Clin Oncol
, vol.9
, pp. 314-326
-
-
Peters, S.1
Adjei, A.A.2
-
39
-
-
79955420135
-
Induction of MET by ionizing radiation and its role in radioresistance and invasive growth of cancer
-
Bacco Fd, Luraghi P, Medico E, Reato G, Girolami F, Perera T, et al. Induction of MET by ionizing radiation and its role in radioresistance and invasive growth of cancer. JNCI J Natl Cancer Inst 2011;103:645-61.
-
(2011)
JNCI J Natl Cancer Inst
, vol.103
, pp. 645-661
-
-
Fd, B.1
Luraghi, P.2
Medico, E.3
Reato, G.4
Girolami, F.5
Perera, T.6
-
40
-
-
0032537813
-
Scatter factor protects epithelial and carcinoma cells against apoptosis induced by DNA-damaging agents
-
Fan S, Wang JA, Yuan RQ, Rockwell S, Andres J, Zlatapolskiy A, et al. Scatter factor protects epithelial and carcinoma cells against apoptosis induced by DNA-damaging agents. Oncogene 1998;17:131-41.
-
(1998)
Oncogene
, vol.17
, pp. 131-141
-
-
Fan, S.1
Wang, J.A.2
Yuan, R.Q.3
Rockwell, S.4
Andres, J.5
Zlatapolskiy, A.6
-
41
-
-
80052971224
-
Head neck squamous cell carcinoma c-Met+ cells display cancer stem cell properties and are responsible for cisplatin-resistance and metastasis
-
Sun S, Wang Z. Head neck squamous cell carcinoma c-Met+ cells display cancer stem cell properties and are responsible for cisplatin-resistance and metastasis. Int J Cancer 2011;129:2337-48.
-
(2011)
Int J Cancer
, vol.129
, pp. 2337-2348
-
-
Sun, S.1
Wang, Z.2
-
42
-
-
79957846955
-
The PTEN/PI3K/Akt pathway regulates stem-like cells in primary esophageal carcinoma cells
-
Li H, Gao Q, Guo L, Lu SH. The PTEN/PI3K/Akt pathway regulates stem-like cells in primary esophageal carcinoma cells. Cancer Biol Ther 2011;11:950-8.
-
(2011)
Cancer Biol Ther
, vol.11
, pp. 950-958
-
-
Li, H.1
Gao, Q.2
Guo, L.3
Lu, S.H.4
-
43
-
-
36048963331
-
Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance
-
Zhou J, Wulfkuhle J, Zhang H, Gu P, Yang Y, Deng J, et al. Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance. Proc Natl Acad Sci USA 2007;104:16158-63.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 16158-16163
-
-
Zhou, J.1
Wulfkuhle, J.2
Zhang, H.3
Gu, P.4
Yang, Y.5
Deng, J.6
-
44
-
-
77954901231
-
Singlemarker identification of head and neck squamous cell carcinoma cancer stem cells with aldehyde dehydrogenase
-
Clay MR, Tabor M, Owen JH, Carey TE, Bradford CR, Wolf GT, et al. Singlemarker identification of head and neck squamous cell carcinoma cancer stem cells with aldehyde dehydrogenase. Head Neck 2010;32:1195-201.
-
(2010)
Head Neck
, vol.32
, pp. 1195-1201
-
-
Clay, M.R.1
Tabor, M.2
Owen, J.H.3
Carey, T.E.4
Bradford, C.R.5
Wolf, G.T.6
-
45
-
-
84927001056
-
Cancer stem-like cells from head and neck cancers are chemosensitized by the Wnt antagonist, sFRP4, by inducing apoptosis, decreasing stemness, drug resistance and epithelial to mesenchymal transition
-
Warrier S, Bhuvanalakshmi G, Arfuso F, Rajan G, Millward M, Dharmarajan A. Cancer stem-like cells from head and neck cancers are chemosensitized by the Wnt antagonist, sFRP4, by inducing apoptosis, decreasing stemness, drug resistance and epithelial to mesenchymal transition. Cancer Gene Ther 2014;21:381-8.
-
(2014)
Cancer Gene Ther
, vol.21
, pp. 381-388
-
-
Warrier, S.1
Bhuvanalakshmi, G.2
Arfuso, F.3
Rajan, G.4
Millward, M.5
Dharmarajan, A.6
-
46
-
-
84893797666
-
Targeting head and neck cancer stem cells to overcome resistance to photon and carbon ion radiation
-
Bertrand G, Maalouf M, Boivin A, Battiston-Montagne P, Beuve M, Levy A, et al. Targeting head and neck cancer stem cells to overcome resistance to photon and carbon ion radiation. Stem Cell Rev 2014;10:114-26.
-
(2014)
Stem Cell Rev
, vol.10
, pp. 114-126
-
-
Bertrand, G.1
Maalouf, M.2
Boivin, A.3
Battiston-Montagne, P.4
Beuve, M.5
Levy, A.6
|