Effect of a sigma-1 receptor agonist, cutamesine dihydrochloride (SA4503), on photoreceptor cell death against light-induced damage

Experimental Eye Research

Volumn 132, Issue , 2015, Pages 64-72

  Shimazawa, Masamitsu ^a   Sugitani, Sou ^a   Inoue, Yuki ^a   Tsuruma, Kazuhiro ^a   Hara, Hideaki ^a  

^a GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Caspase 3 7 activity; Endoplasmic reticulum stress; Photoreceptor degeneration; Retinal dysfunction; Sigma 1 receptor

Indexed keywords

CASPASE 3; CASPASE 7; CUTAMESINE; N [2 (3,4 DICHLOROPHENYL)ETHYL] 2 DIMETHYLAMINO N METHYLETHYLAMINE; SIGMA 1 OPIATE RECEPTOR; CASPASE; PIPERAZINE DERIVATIVE; SIGMA OPIATE RECEPTOR; SIGMA-1 RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DEATH; CONTROLLED STUDY; DRUG EFFECT; ELECTRORETINOGRAPHY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; LIGHT DAMAGE; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; PHOTORECEPTOR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINA INJURY; ADVERSE EFFECTS; AGONISTS; ANIMAL; CELL CULTURE; DRUG EFFECTS; ENDOPLASMIC RETICULUM; LIGHT; METABOLISM; PHYSIOLOGY; RADIATION RESPONSE; RETINA;

ANIMALS; CASPASES; CELL DEATH; CELLS, CULTURED; ELECTRORETINOGRAPHY; ENDOPLASMIC RETICULUM; LIGHT; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; PHOTORECEPTOR CELLS, VERTEBRATE; PIPERAZINES; RECEPTORS, SIGMA; RETINA;

EID: 84922619543     PISSN: 00144835     EISSN: 10960007     Source Type: Journal    
DOI: 10.1016/j.exer.2015.01.017     Document Type: Article

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