Pregnenolone sulfate decreases intraocular pressure and changes expression of sigma receptor in a model of chronic ocular hypertension

Molecular Biology Reports

Volumn 39, Issue 6, 2012, Pages 6607-6614

  Sun, Xian ^a   Cheng, Fang ^a   Meng, Bo ^a   Yang, Binbin ^a   Song, Wulian ^a   Yuan, Huiping ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Glaucoma; Intraocular pressure; Neuroprotection; Retinal ganglion cell; Sigma receptor 1

Indexed keywords

MESSENGER RNA; PREGNENOLONE SULFATE; SIGMA OPIATE RECEPTOR; SIGMA OPIATE RECEPTOR 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CHRONIC DISEASE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; GENE; HISTOPATHOLOGY; IMMUNOFLUORESCENCE TEST; INTRAOCULAR HYPERTENSION; INTRAOCULAR PRESSURE; NEUROPROTECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; OCULAR BLOOD VESSEL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; RETINA GANGLION CELL; RETINA INNER PLEXIFORM LAYER; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGMA RECEPTOR 1 GENE; WESTERN BLOTTING;

ANIMALS; CELL COUNT; DISEASE MODELS, ANIMAL; GENE EXPRESSION; GLAUCOMA; INTRAOCULAR PRESSURE; NEUROPROTECTIVE AGENTS; PREGNENOLONE; RATS; RATS, WISTAR; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, SIGMA; RETINA; RETINAL GANGLION CELLS;

RATTUS;

EID: 84864289249     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-012-1491-5     Document Type: Article

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