An evaluation of a human stem cell line to identify risk of developmental neurotoxicity with antiepileptic drugs

Toxicology in Vitro

Volumn 29, Issue 3, 2015, Pages 592-599

  Cao, William S ^a   Livesey, John C ^a   Halliwell, Robert F ^a  

^a UNIVERSITY OF THE PACIFIC   (United States)

Author keywords

Anticonvulsant; Human neurons; Neurogenesis; Neurotoxicity; Stem cells; Teratogen

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE; DNA; LAMOTRIGINE; PHENOBARBITAL; VALPROIC ACID;

ARTICLE; CELL CYCLE PHASE; CELL CYCLE PROGRESSION; CELL FUNCTION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DNA FRAGMENTATION; DRUG EFFICACY; DRUG RESPONSE; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR DYNAMICS; MOLECULAR MODEL; NERVE CELL DIFFERENTIATION; NEUROTOXICITY; OUTCOME ASSESSMENT; RISK ASSESSMENT; RISK FACTOR; STEM CELL LINE; CELL CYCLE; CELL DIFFERENTIATION; CELL LINE; CELL SURVIVAL; CHEMICALLY INDUCED; DRUG EFFECTS; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NEUROLOGIC DISEASE; PATHOLOGY; RISK; TOXICITY AND INTOXICATION;

ANIMALIA;

ANTICONVULSANTS; CELL CYCLE; CELL DIFFERENTIATION; CELL LINE; CELL SURVIVAL; DNA FRAGMENTATION; HUMANS; NERVOUS SYSTEM DISEASES; NEURAL STEM CELLS; NEUROGENESIS; NEURONS; NEUROTOXICITY SYNDROMES; RISK;

EID: 84922600329     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2015.01.010     Document Type: Article

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