Valproic acid inhibits neurosphere formation by adult subventricular cells by a lithium-sensitive mechanism

Neuroscience Letters

Volumn 500, Issue 3, 2011, Pages 202-206

  Zhou, Q ^a   Dalgard, C L ^a   Wynder, C ^b   Doughty, M L ^a  

^a UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^b WESTERN UNIVERSITY   (Canada)

Author keywords

Anti epileptic; Early growth factor receptor 1 (Egr1); Extracellular signal regulated kinase (ERK); Histone deacetylase (HDAC) inhibitor; Lithium; Mitogen activated protein kinase (MAPK); Mood stabilizer; Valproate

Indexed keywords

EARLY GROWTH RESPONSE FACTOR 1; LITHIUM; MITOGEN ACTIVATED PROTEIN KINASE 1; NEUROGENIC DIFFERENTIATION FACTOR; PROTEIN TYROSINE KINASE INHIBITOR; VALPROIC ACID;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; ARTICLE; BRAIN CELL; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; DNA SYNTHESIS; DOWN REGULATION; DRUG INHIBITION; FEMALE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SENSITIVITY ANALYSIS; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING;

ADULT STEM CELLS; ANIMALS; ANTICONVULSANTS; ANTIMANIC AGENTS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL PROLIFERATION; CELLS, CULTURED; CEREBRAL VENTRICLES; CREB-BINDING PROTEIN; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DNA; DRUG ANTAGONISM; EARLY GROWTH RESPONSE PROTEIN 1; FEMALE; HISTONE DEACETYLASE INHIBITORS; LITHIUM CHLORIDE; MALE; MICE; MICE, INBRED C57BL; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MULTIPOTENT STEM CELLS; NEUROGENESIS; PHOSPHORYLATION; TRANSCRIPTION, GENETIC; VALPROIC ACID;

EID: 79960622483     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2011.06.037     Document Type: Article

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