Oligodendrocyte ablation triggers central pain independently of innate or adaptive immune responses in mice

Nature Communications

Volumn 5, Issue , 2014, Pages

  Gritsch, Simon ^a   Lu, Jianning ^a   Thilemann, Sebastian ^a   Wörtge, Simone ^b   Möbius, Wiebke ^c,d   Bruttger, Julia ^b   Karram, Khalad ^b   Ruhwedel, Torben ^c   Blanfeld, Michaela ^b   Vardeh, Daniel ^a   Waisman, Ari ^b   Nave, Klaus Armin ^c   Kuner, Rohini ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b JOHANNES GUTENBERG UNIVERSITY   (Germany)

^c MAX PLANCK INSTITUTE OF EXPERIMENTAL MEDICINE   (Germany)

^d Center for Nanoscale Microscopy and Molecular Physiology of the Brain (CNMPB)   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN;

GERM CELL; IMMUNE RESPONSE; NEUROLOGY; PATHOLOGY; RODENT; SENSORY SYSTEM;

ADAPTIVE IMMUNITY; ADULT; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CELL PROLIFERATION; CONTROLLED STUDY; GLIOSIS; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INNATE IMMUNITY; LYMPHOCYTIC INFILTRATION; MICROGLIA; MOTOR COORDINATION; MOTOR PERFORMANCE; MOUSE; NERVE FIBER DEGENERATION; NERVE FIBER TRANSPORT; NEUROPATHIC PAIN; NOCICEPTION; NONHUMAN; OLIGODENDROGLIA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCHWANN CELL; SPINAL CORD DORSAL HORN; SPINOTHALAMIC TRACT; T LYMPHOCYTE; ANIMAL; ASTROCYTE; ELECTRON MICROSCOPY; IMMUNOLOGY; METABOLISM; NERVE FIBER; NEURALGIA; PATHOLOGY; PHYSIOLOGY; SPINAL CORD; ULTRASTRUCTURE;

MUS;

ADAPTIVE IMMUNITY; ANIMALS; ASTROCYTES; AXONS; B-LYMPHOCYTES; IMMUNITY, INNATE; MICE; MICROGLIA; MICROSCOPY, ELECTRON; NEURALGIA; NOCICEPTION; OLIGODENDROGLIA; SPINAL CORD; SPINAL CORD DORSAL HORN; SPINOTHALAMIC TRACTS; T-LYMPHOCYTES;

EID: 84922600207     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms6472     Document Type: Article

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