Epac1 and PDZ-GEF cooperate in Rap1 mediated endothelial junction control

Cellular Signalling

Volumn 23, Issue 12, 2011, Pages 2056-2064

  Pannekoek, Willem Jan ^a   van Dijk, Jantine J G ^a   Chan, On Ying A ^a   Huveneers, Stephan ^a   Linnemann, Jelena R ^a   Spanjaard, Emma ^a   Brouwer, Patricia M ^a   van der Meer, Anne Jan ^a   Zwartkruis, Fried J T ^a   Rehmann, Holger ^a   de Rooij, Johan ^a   Bos, Johannes L ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Adherens Junction; Endothelial barrier function; Epac1; PDZ GEF; Rap1

Indexed keywords

ACTIN; CYCLIC AMP; GREEN FLUORESCENT PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; PDZ GUANINE NUCLEOTIDE EXCHANGE FACTOR PROTEIN; PROTEIN EPAC1; RAP1 PROTEIN; UNCLASSIFIED DRUG; VASCULAR ENDOTHELIAL CADHERIN;

ARTICLE; CELL CONTACT; CELL JUNCTION; CELL STIMULATION; CELL STRAIN HEK293; CONTROLLED STUDY; ENDOTHELIUM; GENETIC PROCEDURES; HUMAN; HUMAN CELL; MONOLAYER CULTURE; PERMEABILITY BARRIER; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PROTEIN INTERACTION; REAL TIME ELECTRIC CELL SUBSTRATE IMPEDANCE SENSING; SIGNAL TRANSDUCTION; UMBILICAL VEIN ENDOTHELIAL CELL;

ACTINS; ADHERENS JUNCTIONS; ADP RIBOSE TRANSFERASES; ANTIGENS, CD; BOTULINUM TOXINS; CADHERINS; CYCLIC AMP; ELECTRIC IMPEDANCE; ENDOTHELIUM, VASCULAR; GENE KNOCKDOWN TECHNIQUES; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HEK293 CELLS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MICROSCOPY, FLUORESCENCE; NERVE TISSUE PROTEINS; RHO GTP-BINDING PROTEINS; RNA INTERFERENCE; TELOMERE-BINDING PROTEINS; TIME-LAPSE IMAGING;

EID: 80053262749     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2011.07.022     Document Type: Article

References (31)

1. Dejana E., Orsenigo F., Lampugnani M.G. J. Cell Sci. 2008, 121:2115-2122.
2. Dejana E. Nat. Rev. Mol. Cell Biol. 2004, 5:261-270.
3. Fukuhara S., Sakurai A., Sano H., Yamagishi A., Somekawa S., Takakura N., Saito Y., Kangawa K., Mochizuki N. Mol. Cell. Biol. 2005, 25:136-146.
4. Moy A.B., Bodmer J.E., Blackwell K., Shasby S., Shasby D.M. Am. J. Physiol. 1998, 274:L1024-L1029.
5. Stelzner T.J., Weil J.V., O'Brien R.F. J. Cell. Physiol. 1989, 139:157-166.
6. Yuan S.Y. Vascul. Pharmacol. 2002, 39:213-223.
7. Birukova A.A., Zagranichnaya T., Fu P., Alekseeva E., Chen W., Jacobson J.R., Birukov K.G. Exp. Cell Res. 2007, 313:2504-2520.
8. Lorenowicz M.J., Fernandez-Borja M., Kooistra M.R., Bos J.L., Hordijk P.L. Eur. J. Cell Biol. 2008, 87:779-792.
9. Gloerich M., Bos J.L. Annu. Rev. Pharmacol. Toxicol. 2010, 50:355-375.
10. Enserink J.M., Christensen A.E., de Rooij J., van Triest M., Schwede F., Genieser H.G., Doskeland S.O., Blank J.L., Bos J.L. Nat. Cell Biol. 2002, 4:901-906.
11. Cullere X., Shaw S.K., Andersson L., Hirahashi J., Luscinskas F.W., Mayadas T.N. Blood 2005, 105:1950-1955.
12. Kooistra M.R., Corada M., Dejana E., Bos J.L. FEBS Lett. 2005, 579:4966-4972.
13. Wittchen E.S., Worthylake R.A., Kelly P., Casey P.J., Quilliam L.A., Burridge K. J. Biol. Chem. 2005, 280:11675-11682.
14. Birukova A.A., Burdette D., Moldobaeva N., Xing J., Fu P., Birukov K.G. Microvasc. Res. 2010, 79:128-138.
15. Sehrawat S., Cullere X., Patel S., Italiano J., Mayadas T.N. Mol. Biol. Cell 2008, 19:1261-1270.
16. Noda K., Zhang J., Fukuhara S., Kunimoto S., Yoshimura M., Mochizuki N. Mol. Biol. Cell 2010, 21:584-596.
17. Glading A., Han J., Stockton R.A., Ginsberg M.H. J. Cell Biol. 2007, 179:247-254.
18. Glading A.J., Ginsberg M.H. Dis. Model. Mech. 2010, 3:73-83.
19. Stockton R.A., Shenkar R., Awad I.A., Ginsberg M.H. J. Exp. Med. 2010, 207:881-896.
20. Pannekoek W.J., Kooistra M.R., Zwartkruis F.J., Bos J.L. Biochim. Biophys. Acta 2009, 1788:790-796.
21. Wei P., Satoh T., Edamatsu H., Aiba A., Setsu T., Terashima T., Kitazawa S., Nakao K., Yoshikawa Y., Tamada M., Kataoka T. Biochem. Biophys. Res. Commun. 2007, 363:106-112.
22. Kanemura H., Satoh T., Bilasy S.E., Ueda S., Hirashima M., Kataoka T. Biochem. Biophys. Res. Commun. 2009, 387:754-759.
23. Dobrosotskaya I.Y., James G.L. Biochem. Biophys. Res. Commun. 2000, 270:903-909.
24. Mino A., Ohtsuka T., Inoue E., Takai Y. Genes Cells 2000, 5:1009-1016.
25. Sakurai A., Fukuhara S., Yamagishi A., Sako K., Kamioka Y., Masuda M., Nakaoka Y., Mochizuki N. Mol. Biol. Cell 2006, 17:966-976.
26. Dube N., Kooistra M.R., Pannekoek W.J., Vliem M.J., Oorschot V., Klumperman J., Rehmann H., Bos J.L. Cell. Signal. 2008, 20:1608-1615.
27. Baumer Y., Drenckhahn D., Waschke J. Histochem. Cell Biol. 2008, 129:765-778.
28. Vliem M.J., Ponsioen B., Schwede F., Pannekoek W.J., Riedl J., Kooistra M.R., Jalink K., Genieser H.G., Bos J.L., Rehmann H. Chembiochem 2008, 9:2052-2054.
29. van Triest M., Bos J.L. Methods Mol. Biol. 2004, 250:97-102.
30. Allingham M.J., van Buul J.D., Burridge K. J. Immunol. 2007, 179:4053-4064.
31. Asuri S., Yan J., Paranavitana N.C., Quilliam L.A. J. Cell. Biochem. 2008, 105:1027-1037.