Xanthine oxidase inhibitory properties and anti-inflammatory activity of 2-amino-5-alkylidene-thiazol-4-ones

Chemico-Biological Interactions

Volumn 229, Issue , 2015, Pages 73-81

  Smelcerovic, Zaklina ^a   Veljkovic, Andrej ^a   Kocic, Gordana ^a   Yancheva, Denitsa ^b   Petronijevic, Zivomir ^a   Anderluh, Marko ^c   Smelcerovic, Andrija ^a  

^a UNIVERSITY OF NI   (Serbia)

^b BULGARIAN ACADEMY OF SCIENCES   (Bulgaria)

^c UNIVERSITY OF LJUBLJANA   (Slovenia)

Author keywords

2 Amino 5 alkylidene thiazol 4 ones; Anti inflammatory activity; Molecular docking; NF B inhibition; Xanthine oxidase inhibition

Indexed keywords

(INDOL 3 YL)METHYLENE; 2 (BENZYLAMINO) 5 [(THIOPHEN 2 YL)METHYLENE]THIAZOL 4(5H) ONE; 2 AMINO 5 ALKYLIDENE THIAZOL 4 ONE DERIVATIVE; 4 CYANOBENZYLIDENE; 4 [(2 BENZYLAMINO 4 OXOTHIAZOL 5(4H) YLIDENE) METHYL]BENZONITRILE; BENZYLIDENE DERIVATIVE; CARBENE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NITRILE; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG; XANTHINE OXIDASE; ANTIINFLAMMATORY AGENT; ENZYME INHIBITOR;

ADULT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; COMPUTER PROGRAM; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME INHIBITION; ENZYME STRUCTURE; HUMAN; HUMAN CELL; IC50; IN VITRO STUDY; MALE; MOLECULAR DOCKING; NONHUMAN; NORMAL HUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PERMEABILITY; RAT; SOLUBILITY; YOUNG ADULT; AMINATION; ANIMAL; ANTAGONISTS AND INHIBITORS; BOVINAE; CHEMISTRY; DRUG EFFECTS; IMMUNOLOGY; MONONUCLEAR CELL;

RATTUS;

AMINATION; ANIMALS; ANTI-INFLAMMATORY AGENTS; CATTLE; ENZYME INHIBITORS; HUMANS; LEUKOCYTES, MONONUCLEAR; MOLECULAR DOCKING SIMULATION; NF-KAPPA B; RATS; THIAZOLES; XANTHINE OXIDASE;

EID: 84922554357     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2015.01.022     Document Type: Article

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