Two 6-(propan-2-yl)-4-methyl-morpholine-2,5-diones as new non-purine xanthine oxidase inhibitors and anti-inflammatory agents

Food and Chemical Toxicology

Volumn 55, Issue , 2013, Pages 493-497

  Smelcerovic, Andrija ^a   Rangelov, Miroslav ^b   Smelcerovic, Zaklina ^a   Veljkovic, Andrej ^a   Cherneva, Emiliya ^c   Yancheva, Denitsa ^b   Nikolic, Goran M ^a   Petronijevic, Zivomir ^a   Kocic, Gordana ^a  

^a UNIVERSITY OF NI   (Serbia)

^b INSTITUTE OF ORGANIC CHEMISTRY   (Bulgaria)

^c MEDICAL UNIVERSITY OF SOFIA   (Bulgaria)

Author keywords

Anti inflamatory activity; Cyclodidepsipeptides; Molecular modeling; NF B; Xanthine oxidase inhibition

Indexed keywords

3 (2 METHYLPROPYL) 6 (PROPAN 2 YL) 4 METHYL MORPHOLINE 2,5 DIONE; 3,6 DI(PROPAN 2 YL) 4 METHYL MORPHOLINE 2,5 DIONE; ALLOPURINOL; ANTIINFLAMMATORY AGENT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; UNCLASSIFIED DRUG; XANTHINE OXIDASE INHIBITOR;

ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BINDING AFFINITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG PROTEIN BINDING; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR DOCKING; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; RAT;

ANTI-INFLAMMATORY AGENTS; CELLS, CULTURED; ENZYME INHIBITORS; HUMANS; MOLECULAR DOCKING SIMULATION; MONOCYTES; MORPHOLINES; XANTHINE OXIDASE;

EID: 84874416687     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2013.01.052     Document Type: Article

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