A naturally occurring mouse model of achromatopsia: Characterization of the mutation in cone transducin and subsequent retinal phenotype

Investigative Ophthalmology and Visual Science

Volumn 54, Issue 5, 2013, Pages 3350-3359

  Jobling, Andrew I ^a   Vessey, Kirstan A ^a   Waugh, Michelle ^a   Mills, Samuel A ^a   Fletcher, Erica L ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Achromatopsia; Cone photoreceptors; Degeneration; Gnat2; Transducin

Indexed keywords

OPSIN; TRANSDUCIN;

AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL STRUCTURE; COLOR BLINDNESS; CONTROLLED STUDY; ELECTRORETINOGRAPHY; GENE; GENE EXPRESSION; GENOTYPE; GLIOSIS; GNAT2 GENE; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; MISSENSE MUTATION; MOUSE; MUELLER CELL; NONHUMAN; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINA BIPOLAR GANGLION CELL; RETINA CONE; RETINA DEGENERATION; RETINA HORIZONTAL NERVE CELL; WESTERN BLOTTING;

ACHROMATOPSIA; CONE PHOTORECEPTORS; DEGENERATION; GNAT2; TRANSDUCIN;

ANIMALS; BLOTTING, WESTERN; COLOR VISION DEFECTS; DISEASE MODELS, ANIMAL; ELECTRORETINOGRAPHY; HETEROTRIMERIC GTP-BINDING PROTEINS; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED BALB C; MUTATION, MISSENSE; OPSINS; PHENOTYPE; POLYMERASE CHAIN REACTION; PROTEIN FOLDING; RETINA; RETINAL CONE PHOTORECEPTOR CELLS; TIME FACTORS; TRANSDUCIN;

EID: 84877661915     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.13-11831     Document Type: Article

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