Hypoxic retinal Müller cells promote vascular permeability by HIF-1-dependent up-regulation of angiopoietin-like 4

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 36, 2013, Pages

  Xin, Xiaoban ^a   Rodrigues, Murilo ^a   Umapathi, Mahaa ^a   Kashiwabuchi, Fabiana ^a   Ma, Tao ^b,c,d   Babapoor Farrokhran, Savalan ^a   Wang, Shuang ^a   Hu, Jiadi ^b,c,d   Bhutto, Imran ^a   Welsbie, Derek S ^a   Duh, Elia J ^a   Handa, James T ^a   Eberhart, Charles G ^a   Lutty, Gerard ^a   Semenza, Gregg L ^e,f   Montaner, Silvia ^b,c,d   Sodhi, Akrit ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b Creighton Universityc   (United States)

^c School of Medicine   (United States)

^d UNIVERSITY OF MARYLAND   (United States)

^e Institute for Cell Engineering   (United States)

^f JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Angiogenesis; Diabetes; Retinal vein occlusion; Transcription factor

Indexed keywords

ANGIOPOIETIN; ANGIOPOIETIN LIKE 4; CYTOKINE; HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; OXYGEN; UNCLASSIFIED DRUG; VASCULOTROPIN; ANGPTL4 PROTEIN, MOUSE; VASCULOTROPIN A;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLOOD VESSEL PERMEABILITY; CELL HYPOXIA; CONTROLLED STUDY; CYTOKINE RELEASE; DIABETIC RETINOPATHY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MOUSE; MUELLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RECEPTOR UPREGULATION; RETINA; RETINA EDEMA; RETINA ISCHEMIA; RETINOPATHY; ANIMAL; C57BL MOUSE; CAPILLARY PERMEABILITY; CELL CULTURE; CYTOLOGY; DNA MICROARRAY; GENE EXPRESSION PROFILING; GENETICS; ISCHEMIA; METABOLISM; RETINA NERVE CELL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING;

ANGIOPOIETINS; ANIMALS; BLOTTING, WESTERN; CAPILLARY PERMEABILITY; CELL HYPOXIA; CELLS, CULTURED; DIABETIC RETINOPATHY; FEMALE; GENE EXPRESSION PROFILING; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNOHISTOCHEMISTRY; ISCHEMIA; MICE; MICE, INBRED C57BL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RETINAL NEURONS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84883319645     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1217091110     Document Type: Article

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