Computer-based Cognitive Training for ADHD. A Review of Current Evidence.

Child and Adolescent Psychiatric Clinics of North America

Volumn 23, Issue 4, 2014, Pages 807-824

  Sonuga Barke, Edmund ^a,b   Brandeis, Daniel ^c,d   Holtmann, Martin ^e   Cortese, Samuele ^f,g  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b GHENT UNIVERSITY   (Belgium)

^c UNIVERSITY OF ZURICH   (Switzerland)

^d CENTRAL INSTITUTE OF MENTAL HEALTH   (Germany)

^e RUHR UNIVERSITY BOCHUM   (Germany)

^f CAMBRIDGE UNIVERSITY HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

^g UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

ADHD; Attentional control; Brain plasticity; Cognitive training; Inhibitory control; Randomized controlled trial; Treatment; Working memory

Indexed keywords

POLYUNSATURATED FATTY ACID;

ATTENTION DEFICIT DISORDER; CLINICAL DECISION MAKING; COGNITIVE THERAPY; COMPUTER ASSISTED THERAPY; DISEASE ASSOCIATION; DRUG EFFICACY; EVIDENCE BASED MEDICINE; EXECUTIVE FUNCTION; HUMAN; MENTAL CAPACITY; META ANALYSIS (TOPIC); NERVE CELL PLASTICITY; NEUROANATOMY; NEUROPSYCHOLOGICAL TEST; PSYCHOSOCIAL CARE; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SOCIAL ADAPTATION; SOCIAL LEARNING; TREATMENT DURATION; TREATMENT OUTCOME; WORKING MEMORY; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; COMPUTER INTERFACE; DEVICES; PHYSIOLOGY; PROCEDURES; SHORT TERM MEMORY;

ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; COGNITIVE THERAPY; EXECUTIVE FUNCTION; HUMANS; MEMORY, SHORT-TERM; USER-COMPUTER INTERFACE;

EID: 84922543609     PISSN: 10564993     EISSN: 15580490     Source Type: Journal    
DOI: 10.1016/j.chc.2014.05.009     Document Type: Review

References (98)

1. Ramos-Quiroga J.A., Montoya A., Kutzelnigg A., et al. Attention deficit hyperactivity disorder in the European adult population: prevalence, disease awareness, and treatment guidelines. Curr Med Res Opin 2013, 29(9):1093-1104.
2. Willcutt E.G., Nigg J.T., Pennington B.F., et al. Validity of DSM-IV attention deficit/hyperactivity disorder symptom dimensions and subtypes. JAbnorm Psychol 2012, 121(4):991-1010.
3. Connor D.F., Doerfler L.A. ADHD with comorbid oppositional defiant disorder or conduct disorder: discrete or nondistinct disruptive behavior disorders?. JAtten Disord 2008, 12(2):126-134.
4. Williams E.D., Reimherr F.W., Marchant B.K., et al. Personality disorder in ADHD Part 1: assessment of personality disorder in adult ADHD using data from a clinical trial of OROS methylphenidate. Ann Clin Psychiatry 2010, 22(2):84-93.
5. Humphreys K.L., Katz S.J., Lee S.S., et al. The association of ADHD and depression: mediation by peer problems and parent-child difficulties in two complementary samples. JAbnorm Psychol 2013, 122(3):854-867.
6. Lee S.S., Falk A.E., Aguirre V.P. Association of comorbid anxiety with social functioning in school-age children with and without attention-deficit/hyperactivity disorder (ADHD). Psychiatry Res 2012, 197(1-2):90-96.
7. Tannock R. Rethinking ADHD and LD in DSM-5: proposed changes in diagnostic criteria. JLearn Disabil 2013, 46(1):5-25.
8. Antshel K.M., Zhang-James Y., Faraone S.V. The comorbidity of ADHD and autism spectrum disorder. Expert Rev Neurother 2013, 13(10):1117-1128.
9. Danckaerts M., Sonuga-Barke E.J., Banaschewski T., et al. The quality of life of children with attention deficit/hyperactivity disorder: a systematic review. Eur Child Adolesc Psychiatry 2010, 19(2):83-105.
10. Garner A.A., O'connor B.C., Narad M.E., et al. The relationship between ADHD symptom dimensions, clinical correlates, and functional impairments. JDev Behav Pediatr 2013, 34(7):469-477.
11. Schlander M., Trott G.E., Schwarz O. The health economics of attention deficit hyperactivity disorder in Germany. Part 1: health care utilization and cost of illness. Nervenarzt 2010, 81(3):289-300. [in German].
12. Willcutt E.G., Sonuga-Barke E.J.S., Nigg J.T., et al. Recent developments in neuropsychological models of childhood psychiatric disorders. Biological child psychiatry. Recent trends and developments. Advances in biological psychiatry 2008, vol. 24:195-226. Karger, Basel (Switzerland).
13. Cortese S., Kelly C., Chabernaud C., et al. Toward systems neuroscience of ADHD: a meta- analysis of 55 fMRI studies. Am J Psychiatry 2012, 169(10):1038-1055.
14. Goos L.M., Crosbie J., Payne S., et al. Validation and extension of the endophenotype model in ADHD patterns of inheritance in a family study of inhibitory control. Am J Psychiatry 2009, 166(6):711-717.
15. Rubia K. "Cool" inferior frontostriatal dysfunction in attention-deficit/hyperactivity disorder versus "hot" ventromedial orbitofrontal-limbic dysfunction in conduct disorder: a review. Biol Psychiatry 2011, 69(12):e69-e87.
16. Kasper L.J., Alderson R.M., Hudec K.L. Moderators of working memory deficits in children with attention-deficit/hyperactivity disorder (ADHD): a meta-analytic review. Clin Psychol Rev 2012, 32(7):605-617.
17. Silk T.J., Vance A., Rinehart N., et al. Dysfunction in the fronto-parietal network in attention deficit hyperactivity disorder (ADHD): an fMRI Study. Brain Imaging Behav 2008, 2:123-131.
18. Noreika V., Falter C.M., Rubia K. Timing deficits in attention-deficit/hyperactivity disorder (ADHD): evidence from neurocognitive and neuroimaging studies. Neuropsychologia 2013, 51(2):235-266.
19. Rhodes S.M., Park J., Seth S., et al. Acomprehensive investigation of memory impairment in attention deficit hyperactivity disorder and oppositional defiant disorder. JChild Psychol Psychiatry 2012, 53(2):128-137.
20. Metin B., Roeyers H., Wiersema J.R., et al. ADHD performance reflects inefficient but not impulsive information processing: a diffusion model analysis. Neuropsychology 2013, 27(2):193-200.
21. Sonuga-Barke E.J. Editorial: ADHD as a reinforcement disorder - moving from general effects to identifying (six) specific models to test. JChild Psychol Psychiatry 2011, 52(9):917-918.
22. Sonuga-Barke E.J., Fairchild G. Neuroeconomics of attention-deficit/hyperactivity disorder: differential influences of medial, dorsal, and ventral prefrontal brain networks on suboptimal decision making?. Biol Psychiatry 2012, 72(2):126-133.
23. Volkow N.D., Wang G.J., Newcorn J.H., et al. Motivation deficit in ADHD is associated with dysfunction of the dopamine reward pathway. Mol Psychiatry 2011, 16(11):1147-1154.
24. van Meel C.S., Heslenfeld D.J., Oosterlaan J., et al. ERPs associated with monitoring and evaluation of monetary reward and punishment in children with ADHD. JChild Psychol Psychiatry 2011, 52(9):942-953.
25. Lemiere J., Danckaerts M., Van H.W., et al. Brain activation to cues predicting inescapable delay in adolescent attention deficit/hyperactivity disorder: an fMRI pilot study. Brain Res 2012, 1450:57-66.
26. Scheres A., Dijkstra M., Ainslie E., et al. Temporal and probabilistic discounting of rewards in children and adolescents: effects of age and ADHD symptoms. Neuropsychologia 2006, 44(11):2092-2103.
27. Marco R., Miranda A., Schlotz W., et al. Delay and reward choice in ADHD: an experimental test of the role of delay aversion. Neuropsychology 2009, 23(3):367-380.
28. Wilbertz G., Trueg A., Sonuga-Barke E.J., et al. Neural and psychophysiological markers of delay aversion in attention-deficit hyperactivity disorder. JAbnorm Psychol 2013, 122(2):566-572.
29. Sonuga-Barke E.J., Wiersema J.R., van der Meere J.J., et al. Context-dependent dynamic processes in attention deficit/hyperactivity disorder: differentiating common and unique effects of state regulation deficits and delay aversion. Neuropsychol Rev 2010, 20(1):86-102.
30. Fair D.A., Bathula D., Nikolas M.A., et al. Distinct neuropsychological subgroups in typically developing youth inform heterogeneity in children with ADHD. Proc Natl Acad Sci USA 2012, 109(17):6769-6774.
31. Liddle E.B., Hollis C., Batty M.J., et al. Task-related default mode network modulation and inhibitory control in ADHD: effects of motivation and methylphenidate. JChild Psychol Psychiatry 2011, 52(7):761-771.
32. Sonuga-Barke E.J., Castellanos F.X. Spontaneous attentional fluctuations in impaired states and pathological conditions: a neurobiological hypothesis. Neurosci Biobehav Rev 2007, 31(7):977-986.
33. de Z.P., Weusten J., van D.S., et al. Deficits in cognitive control, timing and reward sensitivity appear to be dissociable in ADHD. PLoS One 2012, 7(12):e51416.
34. Lambek R., Tannock R., Dalsgaard S., et al. Validating neuropsychological subtypes of ADHD: how do children with and without an executive function deficit differ?. JChild Psychol Psychiatry 2010, 51(8):895-904.
35. Nigg J.T., Casey B.J. An integrative theory of attention-deficit/hyperactivity disorder based on the cognitive and affective neurosciences. Dev Psychopathol 2005, 17(3):785-806.
36. Solanto M.V., Abikoff H., Sonuga-Barke E., et al. The ecological validity of delay aversion and response inhibition as measures of impulsivity in AD/HD: a supplement to the NIMH multimodal treatment study of AD/HD. JAbnorm Child Psychol 2001, 29(3):215-228.
37. Sonuga-Barke E.J. Psychological heterogeneity in AD/HD-a dual pathway model of behaviour and cognition. Behav Brain Res 2002, 130(1-2):29-36.
38. Sonuga-Barke E., Bitsakou P., Thompson M. Beyond the dual pathway model: evidence for the dissociation of timing, inhibitory, and delay-related impairments in attention- deficit/hyperactivity disorder. JAm Acad Child Adolesc Psychiatry 2010, 49(4):345-355.
39. Coghill D., Nigg J., Rothenberger A., et al. Whither causal models in the neuroscience of ADHD?. Dev Sci 2005, 8(2):105-114.
40. Kuntsi J., Pinto R., Price T.S., et al. The separation of ADHD inattention and hyperactivity-impulsivity symptoms: pathways from genetic effects to cognitive impairments and symptoms. JAbnorm Child Psychol 2014, 42(1):127-136.
41. Bitsakou P., Psychogiou L., Thompson M., et al. Delay aversion in attention deficit/hyperactivity disorder: an empirical investigation of the broader phenotype. Neuropsychologia 2009, 47(2):446-456.
42. Holmes J., Gathercole S.E., Dunning D.L. Poor working memory: impact and interventions. Advances in child development and behavior: developmental disorders and interventions, vol. 39 2010, 1-43. Academic Press, Burlington. J. Holmes (Ed.).
43. Sonuga-Barke E.J., Sergeant J.A., Nigg J., et al. Executive dysfunction and delay aversion in attention deficit hyperactivity disorder: nosologic and diagnostic implications. Child Adolesc Psychiatr Clin N Am 2008, 17(2):367-384. ix.
44. Taylor E., Dopfner M., Sergeant J., et al. European clinical guidelines for hyperkinetic disorder - first upgrade. Eur Child Adolesc Psychiatry 2004, 13(Suppl 1):I7-I30.
45. Faraone S.V., Buitelaar J. Comparing the efficacy of stimulants for ADHD in children and adolescents using meta-analysis. Eur Child Adolesc Psychiatry 2010, 19(4):353-364.
46. Banaschewski T., Soutullo C., Lecendreux M., et al. Health-related quality of life and functional outcomes from a randomized, controlled study of lisdexamfetamine dimesylate in children and adolescents with attention deficit hyperactivity disorder. CNS Drugs 2013, 27(10):829-840.
47. Ni H.C., Shang C.Y., Gau S.S., et al. Ahead-to-head randomized clinical trial of methylphenidate and atomoxetine treatment for executive function in adults with attention-deficit hyperactivity disorder. Int J Neuropsychopharmacol 2013, 16(9):1959-1973.
48. Coghill D.R., Seth S., Pedroso S., et al. Effects of methylphenidate on cognitive functions in children and adolescents with attention-deficit/hyperactivity disorder: evidence from a systematic review and a meta-analysis. Biol Psychiatry 2013, [Epub ahead of print].
49. Shiels K., Hawk L.W., Reynolds B., et al. Effects of methylphenidate on discounting of delayed rewards in attention deficit/hyperactivity disorder. Exp Clin Psychopharmacol 2009, 17(5):291-301.
50. Sonuga-Barke E.J., Brandeis D., Cortese S., et al. Nonpharmacological interventions for ADHD: systematic review and meta-analyses of randomized controlled trials of dietary and psychological treatments. Am J Psychiatry 2013, 170(3):275-289.
51. Cortese S., Holtmann M., Banaschewski T., et al. Practitioner review: current best practice in the management of adverse events during treatment with ADHD medications in children and adolescents. JChild Psychol Psychiatry 2013, 54(3):227-246.
52. Molina B.S., Hinshaw S.P., Swanson J.M., et al. The MTA at 8 years: prospective follow-up of children treated for combined-type ADHD in a multisite study. JAm Acad Child Adolesc Psychiatry 2009, 48(5):484-500.
53. van de Loo-Neus G.H., Rommelse N., Buitelaar J.K. To stop or not to stop? How long should medication treatment of attention-deficit hyperactivity disorder be extended?. Eur Neuropsychopharmacol 2011, 21(8):584-599.
54. Adler L.D., Nierenberg A.A. Review of medication adherence in children and adults with ADHD. Postgrad Med 2010, 122(1):184-191.
55. Berger I., Dor T., Nevo Y., et al. Attitudes toward attention-deficit hyperactivity disorder (ADHD) treatment: parents' and children's perspectives. JChild Neurol 2008, 23(9):1036-1042.
56. Koerting J., Smith E., Knowles M.M., et al. Barriers to, and facilitators of, parenting programmes for childhood behaviour problems: a qualitative synthesis of studies of parents' and professionals' perceptions. Eur Child Adolesc Psychiatry 2013, 22(11):653-670.
57. Kovshoff H., Williams S., Vrijens M., et al. The decisions regarding ADHD management (DRAMa) study: uncertainties and complexities in assessment, diagnosis and treatment, from the clinician's point of view. Eur Child Adolesc Psychiatry 2012, 21(2):87-99.
58. Stevenson J., Buitelaar J., Cortese S., et al. Research review: the role of diet in thetreatment of attention-deficit/hyperactivity disorder - an appraisal of the evidence on efficacy and recommendations on the design of future studies. JChild Psychol Psychiatry 2014, 55:416-427.
59. Fabiano G.A., Pelham W.E., Coles E.K., et al. Ameta-analysis of behavioral treatments for attention-deficit/hyperactivity disorder. Clin Psychol Rev 2009, 29(2):129-140.
60. Daley D., Oord S.V., Ferrin M., et al. The impact of behavioral interventions for children and adolescents with attention-deficit hyperactivity disorder: a meta-analysis of randomised controlled trials across multiple outcome domains. JAm Acad Child Adolesc Psychiatry 2014, in press.
61. Jolles D.D., Crone E.A. Training the developing brain: a neurocognitive perspective. Front Hum Neurosci 2012, 6:76.
62. Willis S.L., Schaie K.W. Cognitive training and plasticity: theoretical perspective and methodological consequences. Restor Neurol Neurosci 2009, 27(5):375-389.
63. Bahar-Fuchs A., Clare L., Woods B. Cognitive training and cognitive rehabilitation for mild to moderate Alzheimer's disease and vascular dementia. Cochrane Database Syst Rev 2013, (6). CD003260.
64. Vinogradov S., Fisher M., de Villers-Sidani E. Cognitive training for impaired neural systems in neuropsychiatric illness. Neuropsychopharmacology 2012, 37(1):43-76.
65. Witte O.W. Lesion-induced plasticity as a potential mechanism for recovery and rehabilitative training. Curr Opin Neurol 1998, 11(6):655-662.
66. Baltes P. Theoretical propositions of life-span developmental psychology: on the dynamics between growth and decline. Dev Psychol 1987, 23:611-626.
67. Buschkuehl M., Jaeggi S.M., Jonides J. Neuronal effects following working memory training. Dev Cogn Neurosci 2012, 2(Suppl 1):S167-S179.
68. Haier R.J., Siegel B.V., MacLachlan A., et al. Regional glucose metabolic changes after learning a complex visuospatial/motor task: a positron emission tomographic study. Brain Res 1992, 570(1-2):134-143.
69. Olesen P.J., Westerberg H., Klingberg T. Increased prefrontal and parietal activity after training of working memory. Nat Neurosci 2004, 7(1):75-79.
70. Hempel A., Giesel F.L., Garcia Caraballo N.M., et al. Plasticity of cortical activation related to working memory during training. Am J Psychiatry 2004, 161(4):745-747.
71. Poldrack R.A., Gabrieli J.D. Characterizing the neural mechanisms of skill learning and repetition priming: evidence from mirror reading. Brain 2001, 124(Pt 1):67-82.
72. Lewis C.M., Baldassarre A., Committeri G., et al. Learning sculpts the spontaneous activity of the resting human brain. Proc Natl Acad Sci USA 2009, 106(41):17558-17563.
73. Dahlin E., Neely A.S., Larsson A., et al. Transfer of learning after updating training mediated by the striatum. Science 2008, 320(5882):1510-1512.
74. Klingberg T., Fernell E., Olesen P.J., et al. Computerized training of working memory in children with ADHD-a randomized, controlled trial. JAm Acad Child Adolesc Psychiatry 2005, 44(2):177-186.
75. Melby-Lervag M., Hulme C. Is working memory training effective? A meta-analytic review. Dev Psychol 2013, 49(2):270-291.
76. Rapport M.D., Orban S.A., Kofler M.J., et al. Do programs designed to train working memory, other executive functions, and attention benefit children with ADHD? A meta- analytic review of cognitive, academic, and behavioral outcomes. Clin Psychol Rev 2013, 33(8):1237-1252.
77. Karch D., Albers L., Renner G., et al. The efficacy of cognitive training programs in children and adolescents: a meta-analysis. Dtsch Arztebl Int 2013, 110(39):643-652.
78. Hovik K.T., Saunes B.K., Aarlien A.K., et al. RCT of working memory training in ADHD: long-term near-transfer effects. PLoS One 2013, 8(12):e80561.
79. Egeland J., Aarlien A.K., Saunes B.K. Few effects of far transfer of working memory training in ADHD: a randomized controlled trial. PLoS One 2013, 8(10):e75660.
80. Steiner N.J., Frenette E.C., Rene K.M., et al. In-school neurofeedback training for ADHD: sustained improvements from a randomized control trial. Pediatrics 2014, 133(3):483-492.
81. Steiner N.J., Frenette E.C., Rene K.M., et al. Neurofeedback and cognitive attention training for children with attention-deficit hyperactivity disorder in schools. JDev Behav Pediatr 2014, 35(1):18-27.
82. Oord S.V., Ponsioen A.J., Geurts H.M., et al. APilot Study of the efficacy of a computerized executive functioning remediation training with game elements for children with ADHD in an outpatient setting: outcome on parent- and teacher-rated executive functioning and ADHD behavior. JAtten Disord 2012, [Epub ahead of print].
83. Tamm L., Epstein J.N., Peugh J.L., et al. Preliminary data suggesting the efficacy of attention training for school-aged children with ADHD. Dev Cogn Neurosci 2013, 4:16-28.
84. van Dongen-Boomsma M., Vollebregt M.A., Buitelaar J.K., et al. Working memory training in young children with ADHD: a randomized placebo-controlled trial. JChild Psychol Psychiatry 2014, 55(5):460-472.
85. Chacko A., Bedard A.C., Marks D.J., et al. Arandomized clinical trial of Cogmed working memory training in school-age children with ADHD: a replication in a diverse sample using a control condition. JChild Psychol Psychiatry 2014, 55(3):247-255.
86. Gray S.A., Chaban P., Martinussen R., et al. Effects of a computerized working memory training program on working memory, attention, and academics in adolescents with severe LD and comorbid ADHD: a randomized controlled trial. JChild Psychol Psychiatry 2012, 53(12):1277-1284.
87. Green C.T., Long D.L., Green D., et al. Will working memory training generalize to improve off-task behavior in children with attention-deficit/hyperactivity disorder?. Neurotherapeutics 2012, 9(3):639-648.
88. Steiner N.J., Sheldrick R.C., Gotthelf D., et al. Computer-based attention training in the schools for children with attention deficit/hyperactivity disorder: a preliminary trial. Clin Pediatr (Phila) 2011, 50(7):615-622.
89. Klingberg T., Forssberg H., Westerberg H. Training of working memory in children with ADHD. JClin Exp Neuropsychol 2002, 24(6):781-791.
90. Johnstone S.J., Roodenrys S., Phillips E., et al. Apilot study of combined working memory and inhibition training for children with AD/HD. Atten Defic Hyperact Disord 2010, 2(1):31-42.
91. Johnstone S.J., Roodenrys S., Blackman R., et al. Neurocognitive training for children with and without AD/HD. Atten Defic Hyperact Disord 2012, 4(1):11-23.
92. Shalev L., Tsal Y., Mevorach C. Computerized progressive Attentional (CPAT) Program: effective direct intervention for children with ADHD. Child Neuropsychol 2007, 13:382-388.
93. Rabiner D.L., Murray D.W., Skinner A.T., et al. Arandomized trial of two promising computer-based interventions for students with attention difficulties. JAbnorm Child Psychol 2010, 38(1):131-142.
94. Hoekzema E., Carmona S., Ramos-Quiroga J., et al. Training-induced neuroanatomical plasticity in ADHD: a tensor-based morphometric study. Hum Brain Mapp 2011, 32(10):1741-1749.
95. Hoekzema E., Carmona S., Tremols V. Enhanced neural activity in frontal and cerebellar circuits after cognitive training in children with attention-deficit/hyperactivity disorder. Hum Brain Mapp 2010, 31(12):1942-1950.
96. Sonuga-Barke E.J. On the reorganization of incentive structure to promote delay tolerance: a therapeutic possibility for AD/HD?. Neural Plast 2004, 11(1-2):23-28.
97. Sonuga-Barke E.J., Halperin J.M. Developmental phenotypes and causal pathways in attention deficit/hyperactivity disorder: potential targets for early intervention?. JChild Psychol Psychiatry 2010, 51(4):368-389.
98. Halperin J.M., Marks D.J., Bedard A.C., et al. Training executive, attention, and motor skills: a proof-of-concept study in preschool children with ADHD. JAtten Disord 2013, 17(8):711-721.