Lower Methylation of Glucocorticoid Receptor Gene Promoter 1F in Peripheral Blood of Veterans with Posttraumatic Stress Disorder

Biological Psychiatry

Volumn 77, Issue 4, 2015, Pages 356-364

  Yehuda, Rachel ^a,b   Flory, Janine D ^a,b   Bierer, Linda M ^a,b   Henn Haase, Clare ^a,c   Lehrner, Amy ^a,b   Desarnaud, Frank ^a,b   Makotkine, Iouri ^a,b   Daskalakis, Nikolaos P ^a,b   Marmar, Charles R ^c   Meaney, Michael J ^d,e  

^a Mental Health Care Center   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d MCGILL UNIVERSITY   (Canada)

^e AGENCY FOR SCIENCE   (Singapore)

Author keywords

Biomarkers; Combat; Cortisol; Glucocorticoid receptor; HPA axis; Methylation; NR3C1 gene; NR3C1 1f promoter; PTSD

Indexed keywords

CYTOSINE; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; HYDROCORTISONE; LYSOZYME; BIOLOGICAL MARKER; DEXAMETHASONE; NR3C1 PROTEIN, HUMAN;

ADULT; ARTICLE; CONTROLLED STUDY; DEXAMETHASONE SUPPRESSION TEST; DNA METHYLATION; ENVIRONMENTAL EXPOSURE; ENZYME INHIBITION; EPIGENETICS; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GLUCOCORTICOID RECEPTOR GENE; HORMONE DETERMINATION; HUMAN; HUMAN CELL; HYDROCORTISONE BLOOD LEVEL; HYDROCORTISONE URINE LEVEL; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; MAJOR CLINICAL STUDY; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; POSTTRAUMATIC STRESS DISORDER; PRIORITY JOURNAL; PROMOTER REGION; RECEPTOR GENE; SURVIVOR; VETERAN; CHEMISTRY; COMPLICATION; GENETIC EPIGENESIS; GENETICS; HYPOPHYSIS ADRENAL SYSTEM; HYPOTHALAMUS; MAJOR DEPRESSION; METABOLISM; MONOCYTE; PSYCHOLOGY; URINE;

ADULT; BIOMARKERS; CYTOSINE; DEPRESSIVE DISORDER, MAJOR; DEXAMETHASONE; DNA METHYLATION; EPIGENESIS, GENETIC; HUMANS; HYDROCORTISONE; HYPOTHALAMUS; MALE; MONOCYTES; MURAMIDASE; PITUITARY-ADRENAL SYSTEM; PROMOTER REGIONS, GENETIC; RECEPTORS, GLUCOCORTICOID; STRESS DISORDERS, POST-TRAUMATIC; VETERANS;

EID: 84922543104     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2014.02.006     Document Type: Article

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