Mitochondrial dysfunction in oocytes of obese mothers: Transmission to offspring and reversal by pharmacological endoplasmic reticulum stress inhibitors

Development (Cambridge)

Volumn 142, Issue 4, 2015, Pages 681-691

  Wu, Linda L ^a   Russell, Darryl L ^a   Wong, Siew L ^a   Chen, Miaoxin ^a   Tsai, Te Sha ^b   St John, Justin C ^b   Norman, Robert J ^a   Febbraio, Mark A ^c   Carroll, John ^b   Robker, Rebecca L ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

Author keywords

BGP 15; ER stress; Mitochondria; MtDNA; Obesity; Ovary

Indexed keywords

LIPID; MITOCHONDRIAL DNA; O (2 HYDROXY 3 PIPERIDINOPROPYL)NICOTINIC AMIDOXIME; PENTRAXIN 3; SALUBRINAL; CINNAMIC ACID DERIVATIVE; OXIME; PIPERIDINE DERIVATIVE; THIOUREA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; BLASTOCYST; CELL MATURATION; CELL TRANSFER; CONCEPTION; CONTROLLED STUDY; CUMULUS CELL; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DYSLIPIDEMIA; EMBRYO DEVELOPMENT; ENDOPLASMIC RETICULUM STRESS; EXTRACELLULAR MATRIX; FEMALE; FERTILIZATION IN VITRO; FETUS; FETUS (ANATOMY); HYPERINSULINEMIA; KIDNEY; LEAN BODY WEIGHT; LIVER; MATERNAL OBESITY; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; OOCYTE; OVULATION; PRIORITY JOURNAL; PROGENY; SPINDLE CELL; ANALOGS AND DERIVATIVES; ANIMAL; DRUG EFFECTS; GENETICS; IMMUNOHISTOCHEMISTRY; MALE; METABOLISM; MITOCHONDRION; OBESITY; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PREGNANCY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

MUS;

ANIMALS; CINNAMATES; DNA, MITOCHONDRIAL; ENDOPLASMIC RETICULUM STRESS; FEMALE; IMMUNOHISTOCHEMISTRY; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MITOCHONDRIA; OBESITY; OOCYTES; OXIMES; PIPERIDINES; PREGNANCY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; THIOUREA;

EID: 84922516293     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.114850     Document Type: Article

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