-
1
-
-
84906077386
-
Rheumatoid arthritis: nuclear medicine state-of-the-art imaging
-
Rosado-de-Castro P.H., Lopes de Souza S.A., Alexandre D., Barbosa da Fonseca L.M., Gutfilen B. Rheumatoid arthritis: nuclear medicine state-of-the-art imaging. World J Orthop 2014, 5(3):312-318.
-
(2014)
World J Orthop
, vol.5
, Issue.3
, pp. 312-318
-
-
Rosado-de-Castro, P.H.1
Lopes de Souza, S.A.2
Alexandre, D.3
Barbosa da Fonseca, L.M.4
Gutfilen, B.5
-
2
-
-
84920278631
-
Interleukin-32 in inflammatory autoimmune diseases
-
Kim S. Interleukin-32 in inflammatory autoimmune diseases. Immune Netw 2014, 14(3):123-127.
-
(2014)
Immune Netw
, vol.14
, Issue.3
, pp. 123-127
-
-
Kim, S.1
-
3
-
-
84906099391
-
Inflammation, lipid metabolism and cardiovascular risk in rheumatoid arthritis: a qualitative relationship?
-
García-Gómez C., Bianchi M., de la Fuente D., Badimon L., Padró T., Corbella E., et al. Inflammation, lipid metabolism and cardiovascular risk in rheumatoid arthritis: a qualitative relationship?. World J Orthop 2014, 5(3):304-311.
-
(2014)
World J Orthop
, vol.5
, Issue.3
, pp. 304-311
-
-
García-Gómez, C.1
Bianchi, M.2
de la Fuente, D.3
Badimon, L.4
Padró, T.5
Corbella, E.6
-
4
-
-
84906075810
-
Advances in the treatment of cervical rheumatoid: less surgery and less morbidity
-
Mallory G.W., Halasz S.R., Clarke M.J. Advances in the treatment of cervical rheumatoid: less surgery and less morbidity. World J Orthop 2014, 5(3):292-303.
-
(2014)
World J Orthop
, vol.5
, Issue.3
, pp. 292-303
-
-
Mallory, G.W.1
Halasz, S.R.2
Clarke, M.J.3
-
5
-
-
84877248532
-
Apoptosis of rheumatoid arthritis fibroblast-like synoviocytes: possible roles of nitric oxide and the thioredoxin 1
-
Li H., Wan A. Apoptosis of rheumatoid arthritis fibroblast-like synoviocytes: possible roles of nitric oxide and the thioredoxin 1. Mediators Inflamm 2013, 2013:953462.
-
(2013)
Mediators Inflamm
, vol.2013
, pp. 953462
-
-
Li, H.1
Wan, A.2
-
6
-
-
84871778727
-
Duality of fibroblast-like synoviocytes in RA: passive responders and imprinted aggressors
-
Bottini N., Firestein G.S. Duality of fibroblast-like synoviocytes in RA: passive responders and imprinted aggressors. Nat Rev Rheumatol 2013, 9(1):24-33.
-
(2013)
Nat Rev Rheumatol
, vol.9
, Issue.1
, pp. 24-33
-
-
Bottini, N.1
Firestein, G.S.2
-
7
-
-
84898627870
-
Review: treat to target in rheumatoid arthritis: fact, fiction, or hypothesis?
-
Solomon D.H., Bitton A., Katz J.N., Radner H., Brown E.M., Fraenkel L. Review: treat to target in rheumatoid arthritis: fact, fiction, or hypothesis?. Arthritis Rheumatol 2014, 66(4):775-782.
-
(2014)
Arthritis Rheumatol
, vol.66
, Issue.4
, pp. 775-782
-
-
Solomon, D.H.1
Bitton, A.2
Katz, J.N.3
Radner, H.4
Brown, E.M.5
Fraenkel, L.6
-
8
-
-
84880169315
-
Wnt signaling pathway in rheumatoid arthritis, with special emphasis on the different roles in synovial inflammation and bone remodeling
-
Miao C.G., Yang Y.Y., He X., Li X.F., Huang C., Huang Y., et al. Wnt signaling pathway in rheumatoid arthritis, with special emphasis on the different roles in synovial inflammation and bone remodeling. Cell Signal 2013, 25(10):2069-2078.
-
(2013)
Cell Signal
, vol.25
, Issue.10
, pp. 2069-2078
-
-
Miao, C.G.1
Yang, Y.Y.2
He, X.3
Li, X.F.4
Huang, C.5
Huang, Y.6
-
9
-
-
0036845163
-
Regulation of fibronectin and metalloproteinase expression by Wnt signaling in rheumatoid arthritis synoviocytes
-
Sen M., Reifert J., Lauterbach K., Wolf V., Rubin J.S., Corr M., et al. Regulation of fibronectin and metalloproteinase expression by Wnt signaling in rheumatoid arthritis synoviocytes. Arthritis Rheum 2002, 46(11):2867-2877.
-
(2002)
Arthritis Rheum
, vol.46
, Issue.11
, pp. 2867-2877
-
-
Sen, M.1
Reifert, J.2
Lauterbach, K.3
Wolf, V.4
Rubin, J.S.5
Corr, M.6
-
10
-
-
84904314069
-
Wnt some lose some: transcriptional governance of stem cells by Wnt/β-catenin signaling
-
Lien W.H., Fuchs E. Wnt some lose some: transcriptional governance of stem cells by Wnt/β-catenin signaling. Genes Dev 2014, 28(14):1517-1532.
-
(2014)
Genes Dev
, vol.28
, Issue.14
, pp. 1517-1532
-
-
Lien, W.H.1
Fuchs, E.2
-
11
-
-
84887818214
-
Wnt signaling in liver fibrosis: progress, challenges and potential directions
-
Miao C.G., Yang Y.Y., He X., Huang C., Huang Y., Zhang L., et al. Wnt signaling in liver fibrosis: progress, challenges and potential directions. Biochimie 2013, 95(12):2326-2335.
-
(2013)
Biochimie
, vol.95
, Issue.12
, pp. 2326-2335
-
-
Miao, C.G.1
Yang, Y.Y.2
He, X.3
Huang, C.4
Huang, Y.5
Zhang, L.6
-
12
-
-
0035049281
-
Blockade of Wnt-5A/frizzled 5 signaling inhibits rheumatoid synoviocyte activation
-
Sen M., Chamorro M., Reifert J., Corr M., Carson D.A. Blockade of Wnt-5A/frizzled 5 signaling inhibits rheumatoid synoviocyte activation. Arthritis Rheum 2001, 44(4):772-781.
-
(2001)
Arthritis Rheum
, vol.44
, Issue.4
, pp. 772-781
-
-
Sen, M.1
Chamorro, M.2
Reifert, J.3
Corr, M.4
Carson, D.A.5
-
13
-
-
21244440341
-
Expression profiles and functional analyses of Wnt-related genes in human joint disorders
-
Nakamura Y., Nawata M., Wakitani S. Expression profiles and functional analyses of Wnt-related genes in human joint disorders. Am J Pathol 2005, 167(1):97-105.
-
(2005)
Am J Pathol
, vol.167
, Issue.1
, pp. 97-105
-
-
Nakamura, Y.1
Nawata, M.2
Wakitani, S.3
-
14
-
-
7544231797
-
Wnt1 inducible signaling pathway protein-3 regulation and microsatellite structure in arthritis
-
Cheon H., Boyle D.L., Firestein G.S. Wnt1 inducible signaling pathway protein-3 regulation and microsatellite structure in arthritis. J Rheumatol 2004, 31(11):2106-2114.
-
(2004)
J Rheumatol
, vol.31
, Issue.11
, pp. 2106-2114
-
-
Cheon, H.1
Boyle, D.L.2
Firestein, G.S.3
-
15
-
-
84875001588
-
New advances of microRNAs in the pathogenesis of rheumatoid arthritis, with a focus on the crosstalk between DNA methylation and the microRNA machinery
-
Miao C.G., Yang Y.Y., He X., Xu T., Huang C., Huang Y., et al. New advances of microRNAs in the pathogenesis of rheumatoid arthritis, with a focus on the crosstalk between DNA methylation and the microRNA machinery. Cell Signal 2013, 25(5):1118-1125.
-
(2013)
Cell Signal
, vol.25
, Issue.5
, pp. 1118-1125
-
-
Miao, C.G.1
Yang, Y.Y.2
He, X.3
Xu, T.4
Huang, C.5
Huang, Y.6
-
16
-
-
84893758625
-
Epigenetics in rheumatoid arthritis: a primer for rheumatologists
-
Bottini N., Firestein G.S. Epigenetics in rheumatoid arthritis: a primer for rheumatologists. Curr Rheumatol Rep 2013, 15(11):372.
-
(2013)
Curr Rheumatol Rep
, vol.15
, Issue.11
, pp. 372
-
-
Bottini, N.1
Firestein, G.S.2
-
17
-
-
79956154138
-
A mini-review: microRNA in arthritis
-
Nakasa T., Nagata Y., Yamasaki K., Ochi M. A mini-review: microRNA in arthritis. Physiol Genomics 2011, 43(10):566-570.
-
(2011)
Physiol Genomics
, vol.43
, Issue.10
, pp. 566-570
-
-
Nakasa, T.1
Nagata, Y.2
Yamasaki, K.3
Ochi, M.4
-
18
-
-
77956511013
-
MicroRNA-146a expresses in interleukin-17 producing T cells in rheumatoid arthritis patients
-
Niimoto T., Nakasa T., Ishikawa M., Okuhara A., Izumi B., Deie M., et al. MicroRNA-146a expresses in interleukin-17 producing T cells in rheumatoid arthritis patients. BMC Musculoskelet Disord 2010, 11:209.
-
(2010)
BMC Musculoskelet Disord
, vol.11
, pp. 209
-
-
Niimoto, T.1
Nakasa, T.2
Ishikawa, M.3
Okuhara, A.4
Izumi, B.5
Deie, M.6
-
19
-
-
84864742290
-
MiR-146a regulates mechanotransduction and pressure-induced inflammation in small airway epithelium
-
Huang Y., Crawford M., Higuita-Castro N., Nana-Sinkam P., Ghadiali S.N. miR-146a regulates mechanotransduction and pressure-induced inflammation in small airway epithelium. FASEB J 2012, 26(8):3351-3364.
-
(2012)
FASEB J
, vol.26
, Issue.8
, pp. 3351-3364
-
-
Huang, Y.1
Crawford, M.2
Higuita-Castro, N.3
Nana-Sinkam, P.4
Ghadiali, S.N.5
-
20
-
-
67650227725
-
MicroRNA-155 modulates the pathogen binding ability of dendritic cells (DCs) by down-regulation of DC-specific intercellular adhesion molecule-3 grabbing non-integrin (DC-SIGN)
-
Martinez-Nunez R.T., Louafi F., Friedmann P.S., Sanchez-Elsner T. MicroRNA-155 modulates the pathogen binding ability of dendritic cells (DCs) by down-regulation of DC-specific intercellular adhesion molecule-3 grabbing non-integrin (DC-SIGN). J Biol Chem 2009, 284(24):16334-16342.
-
(2009)
J Biol Chem
, vol.284
, Issue.24
, pp. 16334-16342
-
-
Martinez-Nunez, R.T.1
Louafi, F.2
Friedmann, P.S.3
Sanchez-Elsner, T.4
-
21
-
-
84885584261
-
Upregulated microRNA-155 expression in peripheral blood mononuclear cells and fibroblast-like synoviocytes in rheumatoid arthritis
-
Long L., Yu P., Liu Y., Wang S., Li R., Shi J., et al. Upregulated microRNA-155 expression in peripheral blood mononuclear cells and fibroblast-like synoviocytes in rheumatoid arthritis. Clin Dev Immunol 2013, 2013:296139.
-
(2013)
Clin Dev Immunol
, vol.2013
, pp. 296139
-
-
Long, L.1
Yu, P.2
Liu, Y.3
Wang, S.4
Li, R.5
Shi, J.6
-
22
-
-
84880787313
-
Overexpression of microRNA-223 in rheumatoid arthritis synovium controls osteoclast differentiation
-
Shibuya H., Nakasa T., Adachi N., Nagata Y., Ishikawa M., Deie M., et al. Overexpression of microRNA-223 in rheumatoid arthritis synovium controls osteoclast differentiation. Mod Rheumatol 2013, 23(4):674-685.
-
(2013)
Mod Rheumatol
, vol.23
, Issue.4
, pp. 674-685
-
-
Shibuya, H.1
Nakasa, T.2
Adachi, N.3
Nagata, Y.4
Ishikawa, M.5
Deie, M.6
-
23
-
-
84904756804
-
Increased miR-223 expression in T cells from patients with rheumatoid arthritis leads to decreased insulin-like growth factor-1-mediated interleukin-10 production
-
Lu M.C., Yu C.L., Chen H.C., Yu H.C., Huang H.B., Lai N.S. Increased miR-223 expression in T cells from patients with rheumatoid arthritis leads to decreased insulin-like growth factor-1-mediated interleukin-10 production. Clin Exp Immunol 2014, 177(3):641-651.
-
(2014)
Clin Exp Immunol
, vol.177
, Issue.3
, pp. 641-651
-
-
Lu, M.C.1
Yu, C.L.2
Chen, H.C.3
Yu, H.C.4
Huang, H.B.5
Lai, N.S.6
-
24
-
-
84866111542
-
Identification of microRNA-221/222 and microRNA-323-3p association with rheumatoid arthritis via predictions using the human tumour necrosis factor transgenic mouse model
-
Pandis I., Ospelt C., Karagianni N., Denis M.C., Reczko M., Camps C., et al. Identification of microRNA-221/222 and microRNA-323-3p association with rheumatoid arthritis via predictions using the human tumour necrosis factor transgenic mouse model. Ann Rheum Dis 2012, 71(10):1716-1723.
-
(2012)
Ann Rheum Dis
, vol.71
, Issue.10
, pp. 1716-1723
-
-
Pandis, I.1
Ospelt, C.2
Karagianni, N.3
Denis, M.C.4
Reczko, M.5
Camps, C.6
-
25
-
-
84901484749
-
Do women with premenopausal-onset rheumatoid arthritis have relative insufficiency or imbalance of adrenocortical steroids?
-
Masi A.T., Rehman A.A., Cutolo M., Aldag J.C. Do women with premenopausal-onset rheumatoid arthritis have relative insufficiency or imbalance of adrenocortical steroids?. Ann N Y Acad Sci 2014, 1317:7-16.
-
(2014)
Ann N Y Acad Sci
, vol.1317
, pp. 7-16
-
-
Masi, A.T.1
Rehman, A.A.2
Cutolo, M.3
Aldag, J.C.4
-
26
-
-
84901807842
-
TNF inhibitor therapy for rheumatoid arthritis
-
Ma X., Xu S. TNF inhibitor therapy for rheumatoid arthritis. Biomed Rep 2013, 1(2):177-184.
-
(2013)
Biomed Rep
, vol.1
, Issue.2
, pp. 177-184
-
-
Ma, X.1
Xu, S.2
-
27
-
-
0035500279
-
Chemokines regulate IL-6 and IL-8 production by fibroblast-like synoviocytes from patients with rheumatoid arthritis
-
Nanki T., Nagasaka K., Hayashida K., Saita Y., Miyasaka N. Chemokines regulate IL-6 and IL-8 production by fibroblast-like synoviocytes from patients with rheumatoid arthritis. J Immunol 2001, 167(9):5381-5385.
-
(2001)
J Immunol
, vol.167
, Issue.9
, pp. 5381-5385
-
-
Nanki, T.1
Nagasaka, K.2
Hayashida, K.3
Saita, Y.4
Miyasaka, N.5
-
28
-
-
34247181323
-
Up-regulation of stromal cell-derived factor 1 (CXCL12) production in rheumatoid synovial fibroblasts through interactions with T lymphocytes: role of interleukin-17 and CD40L-CD40 interaction
-
Kim K.W., Cho M.L., Kim H.R., Ju J.H., Park M.K., Oh H.J., et al. Up-regulation of stromal cell-derived factor 1 (CXCL12) production in rheumatoid synovial fibroblasts through interactions with T lymphocytes: role of interleukin-17 and CD40L-CD40 interaction. Arthritis Rheum 2007, 56(4):1076-1086.
-
(2007)
Arthritis Rheum
, vol.56
, Issue.4
, pp. 1076-1086
-
-
Kim, K.W.1
Cho, M.L.2
Kim, H.R.3
Ju, J.H.4
Park, M.K.5
Oh, H.J.6
-
29
-
-
1942532230
-
T cells, fibroblast-like synoviocytes, and granzyme B+ cytotoxic cells are associated with joint damage in patients with recent onset rheumatoid arthritis
-
Kraan M.C., Haringman J.J., Weedon H., Barg E.C., Smith M.D., Ahern M.J., et al. T cells, fibroblast-like synoviocytes, and granzyme B+ cytotoxic cells are associated with joint damage in patients with recent onset rheumatoid arthritis. Ann Rheum Dis 2004, 63(5):483-488.
-
(2004)
Ann Rheum Dis
, vol.63
, Issue.5
, pp. 483-488
-
-
Kraan, M.C.1
Haringman, J.J.2
Weedon, H.3
Barg, E.C.4
Smith, M.D.5
Ahern, M.J.6
-
30
-
-
84879690525
-
Resveratrol inhibits TNF-α-induced IL-1β, MMP-3 production in human rheumatoid arthritis fibroblast-like synoviocytes via modulation of PI3kinase/Akt pathway
-
Tian J., Chen J.W., Gao J.S., Li L., Xie X. Resveratrol inhibits TNF-α-induced IL-1β, MMP-3 production in human rheumatoid arthritis fibroblast-like synoviocytes via modulation of PI3kinase/Akt pathway. Rheumatol Int 2013, 33(7):1829-1835.
-
(2013)
Rheumatol Int
, vol.33
, Issue.7
, pp. 1829-1835
-
-
Tian, J.1
Chen, J.W.2
Gao, J.S.3
Li, L.4
Xie, X.5
-
31
-
-
0141788392
-
Rheumatoid fibroblast-like synoviocytes overexpress the chemokine stromal cell-derived factor 1 (CXCL12), which supports distinct patterns and rates of CD4+ and CD8+ T cell migration within synovial tissue
-
Bradfield P.F., Amft N., Vernon-Wilson E., Exley A.E., Parsonage G., Rainger G.E., et al. Rheumatoid fibroblast-like synoviocytes overexpress the chemokine stromal cell-derived factor 1 (CXCL12), which supports distinct patterns and rates of CD4+ and CD8+ T cell migration within synovial tissue. Arthritis Rheum 2003, 48(9):2472-2482.
-
(2003)
Arthritis Rheum
, vol.48
, Issue.9
, pp. 2472-2482
-
-
Bradfield, P.F.1
Amft, N.2
Vernon-Wilson, E.3
Exley, A.E.4
Parsonage, G.5
Rainger, G.E.6
-
32
-
-
84901267780
-
Swertiamarin ameliorates inflammation and osteoclastogenesis intermediates in IL-1β induced rat fibroblast-like synoviocytes
-
Saravanan S., Islam V.I., Thirugnanasambantham K., Pazhanivel N., Raghuraman N., Paulraj M.G., et al. Swertiamarin ameliorates inflammation and osteoclastogenesis intermediates in IL-1β induced rat fibroblast-like synoviocytes. Inflamm Res 2014, 63(6):451-462.
-
(2014)
Inflamm Res
, vol.63
, Issue.6
, pp. 451-462
-
-
Saravanan, S.1
Islam, V.I.2
Thirugnanasambantham, K.3
Pazhanivel, N.4
Raghuraman, N.5
Paulraj, M.G.6
-
33
-
-
84880917448
-
Joint-protective effects of compound K, a major ginsenoside metabolite, in rheumatoid arthritis: in vitro evidence
-
Choi Y.S., Kang E.H., Lee E.Y., Gong H.S., Kang H.S., Shin K., et al. Joint-protective effects of compound K, a major ginsenoside metabolite, in rheumatoid arthritis: in vitro evidence. Rheumatol Int 2013, 33(8):1981-1990.
-
(2013)
Rheumatol Int
, vol.33
, Issue.8
, pp. 1981-1990
-
-
Choi, Y.S.1
Kang, E.H.2
Lee, E.Y.3
Gong, H.S.4
Kang, H.S.5
Shin, K.6
-
34
-
-
73649146567
-
The Wnt signaling pathway and rheumatoid arthritis
-
Rabelo Fde S., da Mota L.M., Lima R.A., Lima F.A., Barra G.B., de Carvalho J.F., et al. The Wnt signaling pathway and rheumatoid arthritis. Autoimmun Rev 2010, 9(4):207-210.
-
(2010)
Autoimmun Rev
, vol.9
, Issue.4
, pp. 207-210
-
-
Rabelo Fde, S.1
da Mota, L.M.2
Lima, R.A.3
Lima, F.A.4
Barra, G.B.5
de Carvalho, J.F.6
-
35
-
-
0034646408
-
Expression and function of wingless and frizzled homologs in rheumatoid arthritis
-
Sen M., Lauterbach K., El-Gabalawy H., Firestein G.S., Corr M., Carson D.A. Expression and function of wingless and frizzled homologs in rheumatoid arthritis. Proc Natl Acad Sci USA 2000, 97(6):2791-2796.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.6
, pp. 2791-2796
-
-
Sen, M.1
Lauterbach, K.2
El-Gabalawy, H.3
Firestein, G.S.4
Corr, M.5
Carson, D.A.6
-
36
-
-
84907005214
-
Functions of miR126 and innate immune response
-
Bai Y., Lu W., Han N., Bian H., Zhu M. Functions of miR126 and innate immune response. Yi Chuan 2014, 36(7):631-636.
-
(2014)
Yi Chuan
, vol.36
, Issue.7
, pp. 631-636
-
-
Bai, Y.1
Lu, W.2
Han, N.3
Bian, H.4
Zhu, M.5
-
37
-
-
84904961201
-
MiRNA-181a regulates Toll-like receptor agonist-induced inflammatory response in human fibroblasts
-
Galicia J.C., Naqvi A.R., Ko C.C., Nares S., Khan A.A. MiRNA-181a regulates Toll-like receptor agonist-induced inflammatory response in human fibroblasts. Genes Immunol 2014, 15(5):333-337.
-
(2014)
Genes Immunol
, vol.15
, Issue.5
, pp. 333-337
-
-
Galicia, J.C.1
Naqvi, A.R.2
Ko, C.C.3
Nares, S.4
Khan, A.A.5
-
38
-
-
84922461464
-
MicroRNA regulation in systemic Lupus Erythematosus pathogenesis
-
Yan S., Yim L.Y., Lu L., Lau C.S., Chan V.S. MicroRNA regulation in systemic Lupus Erythematosus pathogenesis. Immune Netw 2014, 14(3):138-148.
-
(2014)
Immune Netw
, vol.14
, Issue.3
, pp. 138-148
-
-
Yan, S.1
Yim, L.Y.2
Lu, L.3
Lau, C.S.4
Chan, V.S.5
-
39
-
-
84892374785
-
MicroRNA-26a negatively regulates toll-like receptor 3 expression of rat macrophages and ameliorates pristane induced arthritis in rats
-
Jiang C., Zhu W., Xu J., Wang B., Hou W., Zhang R., et al. MicroRNA-26a negatively regulates toll-like receptor 3 expression of rat macrophages and ameliorates pristane induced arthritis in rats. Arthritis Res Ther 2014, 16(1):R9.
-
(2014)
Arthritis Res Ther
, vol.16
, Issue.1
, pp. R9
-
-
Jiang, C.1
Zhu, W.2
Xu, J.3
Wang, B.4
Hou, W.5
Zhang, R.6
-
40
-
-
84897019409
-
A novel p53/microRNA-22/Cyr61 axis in synovial cells regulates inflammation in rheumatoid arthritis
-
Lin J., Huo R., Xiao L., Zhu X., Xie J., Sun S., et al. A novel p53/microRNA-22/Cyr61 axis in synovial cells regulates inflammation in rheumatoid arthritis. Arthritis Rheumatol 2014, 66(1):49-59.
-
(2014)
Arthritis Rheumatol
, vol.66
, Issue.1
, pp. 49-59
-
-
Lin, J.1
Huo, R.2
Xiao, L.3
Zhu, X.4
Xie, J.5
Sun, S.6
-
41
-
-
84890139671
-
Rheumatoid arthritis-associated microRNA-155 targets SOCS1 and upregulates TNF-α and IL-1β in PBMCs
-
Li X., Tian F., Wang F. Rheumatoid arthritis-associated microRNA-155 targets SOCS1 and upregulates TNF-α and IL-1β in PBMCs. Int J Mol Sci 2013, 14(12):23910-23921.
-
(2013)
Int J Mol Sci
, vol.14
, Issue.12
, pp. 23910-23921
-
-
Li, X.1
Tian, F.2
Wang, F.3
|