Joint-protective effects of compound K, a major ginsenoside metabolite, in rheumatoid arthritis: In vitro evidence

Rheumatology International

Volumn 33, Issue 8, 2013, Pages 1981-1990

  Choi, Yong Seok ^a   Kang, Eun Ha ^a   Lee, Eun Young ^b,c   Gong, Hyun Sik ^a   Kang, Heun Soo ^c   Shin, Kichul ^c   Lee, Eun Bong ^b,c   Song, Yeong Wook ^b,c   Lee, Yun Jong ^a,c  

^a Seoul National University Bundang Hospital   (South Korea)

^b Seoul National University Hospital   (South Korea)

^c Seoul National University   (South Korea)

Author keywords

Compound K; Ginsenosides; Matrix metalloproteinase; Osteoclast; Osteoclastogenesis; Rheumatoid arthritis

Indexed keywords

COLLAGENASE 3; COMPOUND K; GINSENG SAPONIN; GINSENOSIDE; I KAPPA B ALPHA; INTERSTITIAL COLLAGENASE; MITOGEN ACTIVATED PROTEIN KINASE; STROMELYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TRANSCRIPTION FACTOR NFAT; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL VIABILITY; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBROBLAST; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IN VITRO STUDY; MONOCYTE; NUCLEOTIDE SEQUENCE; OSTEOCLAST; OSTEOCLAST ACTIVITY; OSTEOCLASTOGENESIS; PRIORITY JOURNAL; PROTECTION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHEUMATOID ARTHRITIS; STRUCTURE ACTIVITY RELATION; SYNOVIOCYTE; SYNOVIUM;

ARTHRITIS, RHEUMATOID; FEMALE; GINSENOSIDES; HUMANS; MALE; MATRIX METALLOPROTEINASES; SYNOVIAL MEMBRANE; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84880917448     PISSN: 01728172     EISSN: 1437160X     Source Type: Journal    
DOI: 10.1007/s00296-013-2664-9     Document Type: Article

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