Chemokines regulate IL-6 and IL-8 production by fibroblast-like synoviocytes from patients with rheumatoid arthritis

Journal of Immunology

Volumn 167, Issue 9, 2001, Pages 5381-5385

  Nanki, T ^a   Nagasaka, K ^a   Hayashida, K ^a   Saita, Y ^a   Miyasaka, N ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; INTERLEUKIN 1; INTERLEUKIN 6; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; PERTUSSIS TOXIN; PROTEIN KINASE P60; RANTES; RECEPTOR BLOCKING AGENT; RS 504393; STROMAL CELL DERIVED FACTOR 1; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; HUMAN TISSUE; INFLAMMATORY CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; REGULATORY MECHANISM; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; SKIN FIBROBLAST; SYNOVIOCYTE;

EID: 0035500279     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.167.9.5381     Document Type: Article

References (29)

1. Chemokines: A new classification system and their role in immunity
2. The biology of chemokines and their receptors
3. Chemokines and the arrest of lymphocytes rolling under flow conditions
4. + T cell activation
5. Chemokines and T lymphocyte activation. I. β chemokines costimulate human T lymphocyte activation in vitro
6. Activation of dual T cell signaling pathways by the chemokine RANTES
7. Macrophage inflammatory protein-3β enhances IL-10 production by activated human peripheral blood monocytes and T cells
8. Chemokines in rheumatoid arthritis
9. Fibroblast biology: Effector signals released by the synovial fibroblast in arthritis
10. Enhanced production of monocyte chemoattractant protein-1 in rheumatoid arthritis
11. Production of monocyte chemoattractant protein-1 by inflamed synovial tissue and cultured synoviocytes
12. Expression of the cytokine RANTES in human rheumatoid synovial fibroblasts: Differential regulation of RANTES and interleukin-8 genes by inflammatory cytokines
13. Chemokine expression in rheumatoid arthritis (RA): Evidence of RANTES and macrophage inflammatory protein (MIP)-1 β production by synovial T cells
14. Stromal cell- derived factor-1 -CXC chemokine receptor 4 interactions play a central role in CD4 T cell accumulation in rheumatoid arthritis synovium
15. Persistent induction of the chemokine receptor CXCR4 by TGFβ1 on synovial T cells contributes to their accumulation within the rheumatoid synovium
16. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis
17. Identification of the binding site for a novel class of CCR2b chemokine receptor antagonists: Binding to a common chemokine receptor motif within the helical bundle
18. T-cell adhesion induced by proteoglycan-immobilized cytokine MIP-1 beta
19. Induction of the p161NK4a senescence gene as a new therapeutic strategy for the treatment of rheumatoid arthritis
20. Stromal cell-derived factor-1α and stem cell factor/kit ligand share signaling pathways in hemopoietic progenitors: A potential mechanism for cooperative induction of chemotaxis
21. Fibroblast biology: Signals targeting the synovial fibroblast in arthritis
22. Fibroblast biology: Role of synovial fibroblasts in the pathogenesis of rheumatoid arthritis
23. Therapy of rheumatoid arthritis by blocking IL-6 signal transduction with a humanized anti-IL-6 receptor antibody
24. Cloning of complementary DNA encoding a functional human interleukin-8 receptor
25. Dendritic cells express multiple chemokine receptors used as coreceptors for HIV entry
26. Costimulation of fibroblast collagen and transforming growth factor β1 gene expression by monocyte chemoattractant protein-1 via specific receptors
27. Monocyte chemoattractant protein-1 enhances gene expression and synthesis of matrix metalloproteinase-1 in human fibroblasts by an autocrine IL-1α loop
28. Role of stem cell factor and monocyte chemoattractant protein-1 in the interaction between fibroblasts and mast cells in fibrosis
29. Macrophages in rheumatoid arthritis