In Vivo anti-LAP mAb enhances IL-17/IFN-γ responses and abrogates anti-CD3-induced oral tolerance

International Immunology

Volumn 27, Issue 2, 2015, Pages 73-82

  Da cunha, Andre P ^a,b   Wu, Henry Y ^b   Rezende, Rafael M ^a   Vandeventer, Tyler ^a   Weiner, Howard L ^a,c  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^c Partners Multiple Sclerosis Center   (United States)

Author keywords

Experimental autoimmune encephalomyelitis; Inflammation; Latency associated peptide; Regulatory T cells; TGF beta

Indexed keywords

CD3 ANTIBODY; CD3 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 2; LATENCY ASSOCIATED PEPTIDE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY LAP; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; PERTUSSIS TOXIN; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG; PEPTIDE;

ACTIVE IMMUNIZATION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CD4+ T LYMPHOCYTE; CELL PROLIFERATION; CONTROLLED STUDY; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; FLOW CYTOMETRY; IMMUNOLOGICAL TOLERANCE; IMMUNOREGULATION; IN VIVO STUDY; LYMPH NODE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; SPLEEN CELL; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMICALLY INDUCED; DRUG EFFECTS; IMMUNOLOGY; KNOCKOUT MOUSE; PATHOLOGY;

ANIMALS; ANTIBODIES, MONOCLONAL, MURINE-DERIVED; ANTIGENS, CD3; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; IMMUNE TOLERANCE; INTERFERON-GAMMA; INTERLEUKIN-17; MICE; MICE, KNOCKOUT; PEPTIDES; T-LYMPHOCYTES, REGULATORY;

EID: 84922442486     PISSN: 09538178     EISSN: 14602377     Source Type: Journal    
DOI: 10.1093/intimm/dxu083     Document Type: Article

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