-
1
-
-
84855475193
-
Extent of illicit drug use and dependence, and their contribution to the global burden of disease
-
Degenhardt L, Hall W (2012) Extent of illicit drug use and dependence, and their contribution to the global burden of disease. Lancet 379(9810):55-70.
-
(2012)
Lancet
, vol.379
, Issue.9810
, pp. 55-70
-
-
Degenhardt, L.1
Hall, W.2
-
2
-
-
84872580249
-
-
United Nations Office for Drug Control and Crime Prevention (United Nations, Vienna, Austria
-
United Nations Office for Drug Control and Crime Prevention (2012) World Drug Report 2012 (United Nations, Vienna, Austria), p 112.
-
(2012)
World Drug Report 2012
, pp. 112
-
-
-
3
-
-
78149362118
-
Drug harms in the uk: A multicriteria decision analysis
-
Independent Scientific Committee on Drugs
-
Nutt DJ, King LA, Phillips LD; Independent Scientific Committee on Drugs (2010) Drug harms in the UK: A multicriteria decision analysis. Lancet 376(9752):1558-1565.
-
(2010)
Lancet
, vol.376
, Issue.9752
, pp. 1558-1565
-
-
Nutt, D.J.1
King, L.A.2
Phillips, L.D.3
-
4
-
-
18944396068
-
Psychosocial treatment for opiate abuse and dependence
-
Mayet S, Farrell M, Ferri M, Amato L, Davoli M (2005) Psychosocial treatment for opiate abuse and dependence. Cochrane Database Syst Rev (1):CD004330.
-
(2005)
Cochrane Database Syst Rev
, vol.1
-
-
Mayet, S.1
Farrell, M.2
Ferri, M.3
Amato, L.4
Davoli, M.5
-
5
-
-
0028102246
-
Methadone maintenance treatment in opiate dependence: A review
-
Farrell M, et al. (1994) Methadone maintenance treatment in opiate dependence: A review. BMJ 309(6960):997-1001.
-
(1994)
BMJ
, vol.309
, Issue.6960
, pp. 997-1001
-
-
Farrell, M.1
-
6
-
-
0037460743
-
1-year retention and social function after buprenorphine-Assisted relapse prevention treatment for heroin dependence in Sweden: A randomised, placebo-controlled trial
-
Kakko J, Svanborg KD, Kreek MJ, Heilig M (2003) 1-year retention and social function after buprenorphine-Assisted relapse prevention treatment for heroin dependence in Sweden: A randomised, placebo-controlled trial. Lancet 361(9358):662-668.
-
(2003)
Lancet
, vol.361
, Issue.9358
, pp. 662-668
-
-
Kakko, J.1
Svanborg, K.D.2
Kreek, M.J.3
Heilig, M.4
-
7
-
-
74249119327
-
Outcome of long-term heroin-Assisted treatment offered to chronic, treatment-resistant heroin addicts in the netherlands
-
Blanken P, Hendriks VM, van Ree JM, van den Brink W (2010) Outcome of long-term heroin-Assisted treatment offered to chronic, treatment-resistant heroin addicts in the Netherlands. Addiction 105(2):300-308.
-
(2010)
Addiction
, vol.105
, Issue.2
, pp. 300-308
-
-
Blanken, P.1
Hendriks, V.M.2
Van Ree, J.M.3
Van Den Brink, W.4
-
8
-
-
65349090703
-
Opiate prescription medication dependence and pain perceptions
-
Miller NS, Gold MS (2007) Opiate prescription medication dependence and pain perceptions. J Addict Dis 26(Suppl 1):65-71.
-
(2007)
J Addict Dis
, vol.26
, Issue.SUPPL. 1
, pp. 65-71
-
-
Miller, N.S.1
Gold, M.S.2
-
9
-
-
84865003960
-
Vital signs: Risk for overdose from methadone used for pain relief -United states, 1999-2010
-
Centers for Disease Control and Prevention (CDC
-
Centers for Disease Control and Prevention (CDC) (2012) Vital signs: Risk for overdose from methadone used for pain relief -United States, 1999-2010. MMWR Morb Mortal Wkly Rep 61(26):493-497.
-
(2012)
MMWR Morb Mortal Wkly Rep
, vol.61
, Issue.26
, pp. 493-497
-
-
-
10
-
-
67651122922
-
Comparing overdose mortality associated with methadone and buprenorphine treatment
-
Bell JR, Butler B, Lawrance A, Batey R, Salmelainen P (2009) Comparing overdose mortality associated with methadone and buprenorphine treatment. Drug Alcohol Depend 104(1-2):73-77.
-
(2009)
Drug Alcohol Depend
, vol.104
, Issue.1-2
, pp. 73-77
-
-
Bell, J.R.1
Butler, B.2
Lawrance, A.3
Batey, R.4
Salmelainen, P.5
-
11
-
-
77952237638
-
Prospective comparative assessment of buprenorphine overdose with heroin and methadone: Clinical characteristics and response to antidotal treatment
-
Mégarbane B, et al. (2010) Prospective comparative assessment of buprenorphine overdose with heroin and methadone: Clinical characteristics and response to antidotal treatment. J Subst Abuse Treat 38(4):403-407.
-
(2010)
J Subst Abuse Treat
, vol.38
, Issue.4
, pp. 403-407
-
-
Mégarbane, B.1
-
12
-
-
0023277101
-
Naltrexone and dysphoria: A double-blind placebo controlled trial
-
Malcolm R, O'Neil PM, Von JM, Dickerson PC (1987) Naltrexone and dysphoria: A double-blind placebo controlled trial. Biol Psychiatry 22(6):710-716.
-
(1987)
Biol Psychiatry
, vol.22
, Issue.6
, pp. 710-716
-
-
Malcolm, R.1
O'Neil, P.M.2
Von, J.M.3
Dickerson, P.C.4
-
13
-
-
0022239236
-
Naltrexone-induced dysphoria in former opioid addicts
-
Crowley TJ, Wagner JE, Zerbe G, Macdonald M (1985) Naltrexone-induced dysphoria in former opioid addicts. Am J Psychiatry 142(9):1081-1084.
-
(1985)
Am J Psychiatry
, vol.142
, Issue.9
, pp. 1081-1084
-
-
Crowley, T.J.1
Wagner, J.E.2
Zerbe, G.3
Macdonald, M.4
-
14
-
-
0027464238
-
Pre-And posttranslational regulation of beta-endorphin biosynthesis in the cns: Effects of chronic naltrexone treatment
-
Bronstein DM, Day NC, Gutstein HB, Trujillo KA, Akil H (1993) Pre-And posttranslational regulation of beta-endorphin biosynthesis in the CNS: Effects of chronic naltrexone treatment. J Neurochem 60(1):40-49.
-
(1993)
J Neurochem
, vol.60
, Issue.1
, pp. 40-49
-
-
Bronstein, D.M.1
Day, N.C.2
Gutstein, H.B.3
Trujillo, K.A.4
Akil, H.5
-
15
-
-
0022590807
-
A preliminary study of beta endorphin during chronic naltrexone maintenance treatment in ex-opiate addicts
-
Kosten TR, Kreek MJ, Ragunath J, Kleber HD (1986) A preliminary study of beta endorphin during chronic naltrexone maintenance treatment in ex-opiate addicts. Life Sci 39(1):55-59.
-
(1986)
Life Sci
, vol.39
, Issue.1
, pp. 55-59
-
-
Kosten, T.R.1
Kreek, M.J.2
Ragunath, J.3
Kleber, H.D.4
-
16
-
-
0036308755
-
Naltrexone in the treatment of heroin dependence: Relationship with depression and risk of overdose
-
Ritter AJ (2002) Naltrexone in the treatment of heroin dependence: Relationship with depression and risk of overdose. Aust N Z J Psychiatry 36(2):224-228.
-
(2002)
Aust N Z J Psychiatry
, vol.36
, Issue.2
, pp. 224-228
-
-
Ritter, A.J.1
-
17
-
-
28144465243
-
Safety and immunogenicity of a nicotine conjugate vaccine in current smokers
-
Hatsukami DK, et al. (2005) Safety and immunogenicity of a nicotine conjugate vaccine in current smokers. Clin Pharmacol Ther 78(5):456-467.
-
(2005)
Clin Pharmacol Ther
, vol.78
, Issue.5
, pp. 456-467
-
-
Hatsukami, D.K.1
-
18
-
-
0037081517
-
Human therapeutic cocaine vaccine: Safety and immunogenicity
-
Kosten TR, et al. (2002) Human therapeutic cocaine vaccine: Safety and immunogenicity. Vaccine 20(7-8):1196-1204.
-
(2002)
Vaccine
, vol.20
, Issue.7-8
, pp. 1196-1204
-
-
Kosten, T.R.1
-
19
-
-
22444437907
-
Vaccine pharmacotherapy for the treatment of cocaine dependence
-
Martell BA, Mitchell E, Poling J, Gonsai K, Kosten TR (2005) Vaccine pharmacotherapy for the treatment of cocaine dependence. Biol Psychiatry 58(2):158-164.
-
(2005)
Biol Psychiatry
, vol.58
, Issue.2
, pp. 158-164
-
-
Martell, B.A.1
Mitchell, E.2
Poling, J.3
Gonsai, K.4
Kosten, T.R.5
-
20
-
-
0035882744
-
Mu opioid receptor-mediated g-protein activation by heroin metabolites: Evidence for greater efficacy of 6-monoacetylmorphine compared with morphine
-
Selley DE, et al. (2001) mu Opioid receptor-mediated G-protein activation by heroin metabolites: Evidence for greater efficacy of 6-monoacetylmorphine compared with morphine. Biochem Pharmacol 62(4):447-455.
-
(2001)
Biochem Pharmacol
, vol.62
, Issue.4
, pp. 447-455
-
-
Selley, D.E.1
-
21
-
-
84857729350
-
Developing a vaccine against multiple psychoactive targets: A case study of heroin
-
Stowe GN, et al. (2011) Developing a vaccine against multiple psychoactive targets: A case study of heroin. CNS Neurol Disord Drug Targets 10(8):865-875.
-
(2011)
CNS Neurol Disord Drug Targets
, vol.10
, Issue.8
, pp. 865-875
-
-
Stowe, G.N.1
-
22
-
-
33645064261
-
A novel bivalent morphine/heroin vaccine that prevents relapse to heroin addiction in rodents
-
Anton B, Leff P (2006) A novel bivalent morphine/heroin vaccine that prevents relapse to heroin addiction in rodents. Vaccine 24(16):3232-3240.
-
(2006)
Vaccine
, vol.24
, Issue.16
, pp. 3232-3240
-
-
Anton, B.1
Leff, P.2
-
23
-
-
82955247970
-
A morphine/heroin vaccine with new hapten design attenuates behavioral effects in rats
-
Li QQ, et al. (2011) A morphine/heroin vaccine with new hapten design attenuates behavioral effects in rats. J Neurochem 119(6):1271-1281.
-
(2011)
J Neurochem
, vol.119
, Issue.6
, pp. 1271-1281
-
-
Li, Q.Q.1
-
24
-
-
0016338395
-
Changes in heroin self-Administration by a rhesus monkey after morphine immunisation
-
Bonese KF, Wainer BH, Fitch FW, Rothberg RM, Schuster CR (1974) Changes in heroin self-Administration by a rhesus monkey after morphine immunisation. Nature 252(5485):708-710.
-
(1974)
Nature
, vol.252
, Issue.5485
, pp. 708-710
-
-
Bonese, K.F.1
Wainer, B.H.2
Fitch, F.W.3
Rothberg, R.M.4
Schuster, C.R.5
-
25
-
-
79960649757
-
A vaccine strategy that induces protective immunity against heroin
-
Stowe GN, et al. (2011) A vaccine strategy that induces protective immunity against heroin. J Med Chem 54(14):5195-5204.
-
(2011)
J Med Chem
, vol.54
, Issue.14
, pp. 5195-5204
-
-
Stowe, G.N.1
-
26
-
-
84872728429
-
Selective effects of a morphine conjugate vaccine on heroin and metabolite distribution and heroininduced behaviors in rats
-
Raleigh MD, Pravetoni M, Harris AC, Birnbaum AK, Pentel PR (2013) Selective effects of a morphine conjugate vaccine on heroin and metabolite distribution and heroininduced behaviors in rats. J Pharmacol Exp Ther 344(2):397-406.
-
(2013)
J Pharmacol Exp Ther
, vol.344
, Issue.2
, pp. 397-406
-
-
Raleigh, M.D.1
Pravetoni, M.2
Harris, A.C.3
Birnbaum, A.K.4
Pentel, P.R.5
-
27
-
-
33645509739
-
Pharmacokinetics and pharmacokinetic variability of heroin and its metabolites: Review of the literature
-
Rook EJ, Huitema AD, van den Brink W, van Ree JM, Beijnen JH (2006) Pharmacokinetics and pharmacokinetic variability of heroin and its metabolites: Review of the literature. Curr Clin Pharmacol 1(1):109-118.
-
(2006)
Curr Clin Pharmacol
, vol.1
, Issue.1
, pp. 109-118
-
-
Rook, E.J.1
Huitema, A.D.2
Van Den Brink, W.3
Van Ree, J.M.4
Beijnen, J.H.5
-
28
-
-
33645107718
-
Pharmacokinetics and pharmacodynamics of high doses of pharmaceutically prepared heroin, by intravenous or by inhalation route in opioiddependent patients
-
Rook EJ, et al. (2006) Pharmacokinetics and pharmacodynamics of high doses of pharmaceutically prepared heroin, by intravenous or by inhalation route in opioiddependent patients. Basic Clin Pharmacol Toxicol 98(1):86-96.
-
(2006)
Basic Clin Pharmacol Toxicol
, vol.98
, Issue.1
, pp. 86-96
-
-
Rook, E.J.1
-
29
-
-
0025032241
-
Species differences in metabolism of codeine: Urinary excretion of codeine glucuronide, morphine-3-glucuronide and morphine-6-glucuronide in mice, rats, guinea pigs and rabbits
-
Oguri K, Hanioka N, Yoshimura H (1990) Species differences in metabolism of codeine: Urinary excretion of codeine glucuronide, morphine-3-glucuronide and morphine-6-glucuronide in mice, rats, guinea pigs and rabbits. Xenobiotica 20(7): 683-688.
-
(1990)
Xenobiotica
, vol.20
, Issue.7
, pp. 683-688
-
-
Oguri, K.1
Hanioka, N.2
Yoshimura, H.3
-
30
-
-
77951884731
-
Yohimbine stress potentiates conditioned cue-induced reinstatement of heroin-seeking in rats
-
Banna KM, Back SE, Do P, See RE (2010) Yohimbine stress potentiates conditioned cue-induced reinstatement of heroin-seeking in rats. Behav Brain Res 208(1):144-148.
-
(2010)
Behav Brain Res
, vol.208
, Issue.1
, pp. 144-148
-
-
Banna, K.M.1
Back, S.E.2
Do, P.3
See, R.E.4
-
31
-
-
36249016353
-
Differential effects of blockade of dopamine d1-family receptors in nucleus accumbens core or shell on reinstatement of heroin seeking induced by contextual and discrete cues
-
Bossert JM, Poles GC, Wihbey KA, Koya E, Shaham Y (2007) Differential effects of blockade of dopamine D1-family receptors in nucleus accumbens core or shell on reinstatement of heroin seeking induced by contextual and discrete cues. J Neurosci 27(46):12655-12663.
-
(2007)
J Neurosci
, vol.27
, Issue.46
, pp. 12655-12663
-
-
Bossert, J.M.1
Poles, G.C.2
Wihbey, K.A.3
Koya, E.4
Shaham, Y.5
-
32
-
-
33847011780
-
Heroin-induced reinstatement is specific to compulsive heroin use and dissociable from heroin reward and sensitization
-
Lenoir M, Ahmed SH (2007) Heroin-induced reinstatement is specific to compulsive heroin use and dissociable from heroin reward and sensitization. Neuropsychopharmacology 32(3):616-624.
-
(2007)
Neuropsychopharmacology
, vol.32
, Issue.3
, pp. 616-624
-
-
Lenoir, M.1
Ahmed, S.H.2
-
33
-
-
33748272362
-
Unlimited access to heroin self-Administration: Independent motivational markers of opiate dependence
-
Chen SA, et al. (2006) Unlimited access to heroin self-Administration: Independent motivational markers of opiate dependence. Neuropsychopharmacology 31(12): 2692-2707.
-
(2006)
Neuropsychopharmacology
, vol.31
, Issue.12
, pp. 2692-2707
-
-
Chen, S.A.1
-
34
-
-
79953250110
-
Escalation patterns of varying periods of heroin access
-
Vendruscolo LF, et al. (2011) Escalation patterns of varying periods of heroin access. Pharmacol Biochem Behav 98(4):570-574.
-
(2011)
Pharmacol Biochem Behav
, vol.98
, Issue.4
, pp. 570-574
-
-
Vendruscolo, L.F.1
-
35
-
-
0021322009
-
Effects of opiate antagonists and their quaternary derivatives on heroin self-Administration in the rat
-
Koob GF, Pettit HO, Ettenberg A, Bloom FE (1984) Effects of opiate antagonists and their quaternary derivatives on heroin self-Administration in the rat. J Pharmacol Exp Ther 229(2):481-486.
-
(1984)
J Pharmacol Exp Ther
, vol.229
, Issue.2
, pp. 481-486
-
-
Koob, G.F.1
Pettit, H.O.2
Ettenberg, A.3
Bloom, F.E.4
-
36
-
-
84864742914
-
Craving correlates with mesolimbic responses to heroin-related cues in short-term abstinence from heroin: An event-related fmri study
-
Li Q, et al. (2012) Craving correlates with mesolimbic responses to heroin-related cues in short-term abstinence from heroin: An event-related fMRI study. Brain Res 1469: 63-72.
-
(2012)
Brain Res
, vol.1469
, pp. 63-72
-
-
Li, Q.1
-
37
-
-
39149106754
-
Striatal dopamine d2 receptor binding and dopamine release during cue-elicited craving in recently abstinent opiate-dependent males
-
Zijlstra F, Booij J, van den Brink W, Franken IH (2008) Striatal dopamine D2 receptor binding and dopamine release during cue-elicited craving in recently abstinent opiate-dependent males. Eur Neuropsychopharmacol 18(4):262-270.
-
(2008)
Eur Neuropsychopharmacol
, vol.18
, Issue.4
, pp. 262-270
-
-
Zijlstra, F.1
Booij, J.2
Van Den Brink, W.3
Franken, I.H.4
-
38
-
-
10344222928
-
A role for dopamine in the processing of drug cues in heroin dependent patients
-
Franken IH, Hendriks VM, Stam CJ, Van den BrinkW(2004) A role for dopamine in the processing of drug cues in heroin dependent patients. Eur Neuropsychopharmacol 14(6):503-508.
-
(2004)
Eur Neuropsychopharmacol
, vol.14
, Issue.6
, pp. 503-508
-
-
Franken, I.H.1
Hendriks, V.M.2
Stam, C.J.3
Van Den Brink, W.4
-
39
-
-
84858661736
-
An oxycodone conjugate vaccine elicits drug-specific antibodies that reduce oxycodone distribution to brain and hot-plate analgesia
-
Pravetoni M, et al. (2012) An oxycodone conjugate vaccine elicits drug-specific antibodies that reduce oxycodone distribution to brain and hot-plate analgesia. J Pharmacol Exp Ther 341(1):225-232.
-
(2012)
J Pharmacol Exp Ther
, vol.341
, Issue.1
, pp. 225-232
-
-
Pravetoni, M.1
-
40
-
-
84873905113
-
Reduced antinociception of opioids in rats and mice by vaccination with immunogens containing oxycodone and hydrocodone haptens
-
Pravetoni M, et al. (2013) Reduced antinociception of opioids in rats and mice by vaccination with immunogens containing oxycodone and hydrocodone haptens. J Med Chem 56(3):915-923.
-
(2013)
J Med Chem
, vol.56
, Issue.3
, pp. 915-923
-
-
Pravetoni, M.1
-
41
-
-
84861982138
-
Co-Administration of morphine and oxycodone vaccines reduces the distribution of 6-monoacetylmorphine and oxycodone to brain in rats
-
Pravetoni M, et al. (2012) Co-Administration of morphine and oxycodone vaccines reduces the distribution of 6-monoacetylmorphine and oxycodone to brain in rats. Vaccine 30(31):4617-4624.
-
(2012)
Vaccine
, vol.30
, Issue.31
, pp. 4617-4624
-
-
Pravetoni, M.1
-
42
-
-
0018867072
-
Efficient analysis of experimental observations
-
Dixon WJ (1980) Efficient analysis of experimental observations. Annu Rev Pharmacol Toxicol 20:441-462.
-
(1980)
Annu Rev Pharmacol Toxicol
, vol.20
, pp. 441-462
-
-
Dixon, W.J.1
-
43
-
-
70349301428
-
Determination of heroin and its main metabolites in small sample volumes of whole blood and brain tissue by reversed-phase liquid chromatography-tandem mass spectrometry
-
Karinen R, et al. (2009) Determination of heroin and its main metabolites in small sample volumes of whole blood and brain tissue by reversed-phase liquid chromatography-tandem mass spectrometry. J Anal Toxicol 33(7):345-350.
-
(2009)
J Anal Toxicol
, vol.33
, Issue.7
, pp. 345-350
-
-
Karinen, R.1
-
44
-
-
11144275200
-
Buprenorphine and a crf1 antagonist block the acquisition of opiate withdrawal-induced conditioned place aversion in rats
-
Stinus L, Cador M, Zorrilla EP, Koob GF (2005) Buprenorphine and a CRF1 antagonist block the acquisition of opiate withdrawal-induced conditioned place aversion in rats. Neuropsychopharmacology 30(1):90-98.
-
(2005)
Neuropsychopharmacology
, vol.30
, Issue.1
, pp. 90-98
-
-
Stinus, L.1
Cador, M.2
Zorrilla, E.P.3
Koob, G.F.4
-
45
-
-
0027194404
-
Modulation of cocaine self-Administration in the rat through d-3 dopamine receptors
-
Caine SB, Koob GF (1993) Modulation of cocaine self-Administration in the rat through D-3 dopamine receptors. Science 260(5115):1814-1816.
-
(1993)
Science
, vol.260
, Issue.5115
, pp. 1814-1816
-
-
Caine, S.B.1
Koob, G.F.2
|