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Volumn 110, Issue 22, 2013, Pages 9036-9041

Dynamic vaccine blocks relapse to compulsive intake of heroin

Author keywords

Antinociception; Immunotherapy; Progressive ratio

Indexed keywords

DIAMORPHINE; DRUG METABOLITE; HEROIN VACCINE; MORPHINE; UNCLASSIFIED DRUG; VACCINE;

EID: 84878467308     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1219159110     Document Type: Article
Times cited : (88)

References (45)
  • 1
    • 84855475193 scopus 로고    scopus 로고
    • Extent of illicit drug use and dependence, and their contribution to the global burden of disease
    • Degenhardt L, Hall W (2012) Extent of illicit drug use and dependence, and their contribution to the global burden of disease. Lancet 379(9810):55-70.
    • (2012) Lancet , vol.379 , Issue.9810 , pp. 55-70
    • Degenhardt, L.1    Hall, W.2
  • 2
    • 84872580249 scopus 로고    scopus 로고
    • United Nations Office for Drug Control and Crime Prevention (United Nations, Vienna, Austria
    • United Nations Office for Drug Control and Crime Prevention (2012) World Drug Report 2012 (United Nations, Vienna, Austria), p 112.
    • (2012) World Drug Report 2012 , pp. 112
  • 3
    • 78149362118 scopus 로고    scopus 로고
    • Drug harms in the uk: A multicriteria decision analysis
    • Independent Scientific Committee on Drugs
    • Nutt DJ, King LA, Phillips LD; Independent Scientific Committee on Drugs (2010) Drug harms in the UK: A multicriteria decision analysis. Lancet 376(9752):1558-1565.
    • (2010) Lancet , vol.376 , Issue.9752 , pp. 1558-1565
    • Nutt, D.J.1    King, L.A.2    Phillips, L.D.3
  • 5
    • 0028102246 scopus 로고
    • Methadone maintenance treatment in opiate dependence: A review
    • Farrell M, et al. (1994) Methadone maintenance treatment in opiate dependence: A review. BMJ 309(6960):997-1001.
    • (1994) BMJ , vol.309 , Issue.6960 , pp. 997-1001
    • Farrell, M.1
  • 6
    • 0037460743 scopus 로고    scopus 로고
    • 1-year retention and social function after buprenorphine-Assisted relapse prevention treatment for heroin dependence in Sweden: A randomised, placebo-controlled trial
    • Kakko J, Svanborg KD, Kreek MJ, Heilig M (2003) 1-year retention and social function after buprenorphine-Assisted relapse prevention treatment for heroin dependence in Sweden: A randomised, placebo-controlled trial. Lancet 361(9358):662-668.
    • (2003) Lancet , vol.361 , Issue.9358 , pp. 662-668
    • Kakko, J.1    Svanborg, K.D.2    Kreek, M.J.3    Heilig, M.4
  • 7
    • 74249119327 scopus 로고    scopus 로고
    • Outcome of long-term heroin-Assisted treatment offered to chronic, treatment-resistant heroin addicts in the netherlands
    • Blanken P, Hendriks VM, van Ree JM, van den Brink W (2010) Outcome of long-term heroin-Assisted treatment offered to chronic, treatment-resistant heroin addicts in the Netherlands. Addiction 105(2):300-308.
    • (2010) Addiction , vol.105 , Issue.2 , pp. 300-308
    • Blanken, P.1    Hendriks, V.M.2    Van Ree, J.M.3    Van Den Brink, W.4
  • 8
    • 65349090703 scopus 로고    scopus 로고
    • Opiate prescription medication dependence and pain perceptions
    • Miller NS, Gold MS (2007) Opiate prescription medication dependence and pain perceptions. J Addict Dis 26(Suppl 1):65-71.
    • (2007) J Addict Dis , vol.26 , Issue.SUPPL. 1 , pp. 65-71
    • Miller, N.S.1    Gold, M.S.2
  • 9
    • 84865003960 scopus 로고    scopus 로고
    • Vital signs: Risk for overdose from methadone used for pain relief -United states, 1999-2010
    • Centers for Disease Control and Prevention (CDC
    • Centers for Disease Control and Prevention (CDC) (2012) Vital signs: Risk for overdose from methadone used for pain relief -United States, 1999-2010. MMWR Morb Mortal Wkly Rep 61(26):493-497.
    • (2012) MMWR Morb Mortal Wkly Rep , vol.61 , Issue.26 , pp. 493-497
  • 10
    • 67651122922 scopus 로고    scopus 로고
    • Comparing overdose mortality associated with methadone and buprenorphine treatment
    • Bell JR, Butler B, Lawrance A, Batey R, Salmelainen P (2009) Comparing overdose mortality associated with methadone and buprenorphine treatment. Drug Alcohol Depend 104(1-2):73-77.
    • (2009) Drug Alcohol Depend , vol.104 , Issue.1-2 , pp. 73-77
    • Bell, J.R.1    Butler, B.2    Lawrance, A.3    Batey, R.4    Salmelainen, P.5
  • 11
    • 77952237638 scopus 로고    scopus 로고
    • Prospective comparative assessment of buprenorphine overdose with heroin and methadone: Clinical characteristics and response to antidotal treatment
    • Mégarbane B, et al. (2010) Prospective comparative assessment of buprenorphine overdose with heroin and methadone: Clinical characteristics and response to antidotal treatment. J Subst Abuse Treat 38(4):403-407.
    • (2010) J Subst Abuse Treat , vol.38 , Issue.4 , pp. 403-407
    • Mégarbane, B.1
  • 12
    • 0023277101 scopus 로고
    • Naltrexone and dysphoria: A double-blind placebo controlled trial
    • Malcolm R, O'Neil PM, Von JM, Dickerson PC (1987) Naltrexone and dysphoria: A double-blind placebo controlled trial. Biol Psychiatry 22(6):710-716.
    • (1987) Biol Psychiatry , vol.22 , Issue.6 , pp. 710-716
    • Malcolm, R.1    O'Neil, P.M.2    Von, J.M.3    Dickerson, P.C.4
  • 13
    • 0022239236 scopus 로고
    • Naltrexone-induced dysphoria in former opioid addicts
    • Crowley TJ, Wagner JE, Zerbe G, Macdonald M (1985) Naltrexone-induced dysphoria in former opioid addicts. Am J Psychiatry 142(9):1081-1084.
    • (1985) Am J Psychiatry , vol.142 , Issue.9 , pp. 1081-1084
    • Crowley, T.J.1    Wagner, J.E.2    Zerbe, G.3    Macdonald, M.4
  • 14
    • 0027464238 scopus 로고
    • Pre-And posttranslational regulation of beta-endorphin biosynthesis in the cns: Effects of chronic naltrexone treatment
    • Bronstein DM, Day NC, Gutstein HB, Trujillo KA, Akil H (1993) Pre-And posttranslational regulation of beta-endorphin biosynthesis in the CNS: Effects of chronic naltrexone treatment. J Neurochem 60(1):40-49.
    • (1993) J Neurochem , vol.60 , Issue.1 , pp. 40-49
    • Bronstein, D.M.1    Day, N.C.2    Gutstein, H.B.3    Trujillo, K.A.4    Akil, H.5
  • 15
    • 0022590807 scopus 로고
    • A preliminary study of beta endorphin during chronic naltrexone maintenance treatment in ex-opiate addicts
    • Kosten TR, Kreek MJ, Ragunath J, Kleber HD (1986) A preliminary study of beta endorphin during chronic naltrexone maintenance treatment in ex-opiate addicts. Life Sci 39(1):55-59.
    • (1986) Life Sci , vol.39 , Issue.1 , pp. 55-59
    • Kosten, T.R.1    Kreek, M.J.2    Ragunath, J.3    Kleber, H.D.4
  • 16
    • 0036308755 scopus 로고    scopus 로고
    • Naltrexone in the treatment of heroin dependence: Relationship with depression and risk of overdose
    • Ritter AJ (2002) Naltrexone in the treatment of heroin dependence: Relationship with depression and risk of overdose. Aust N Z J Psychiatry 36(2):224-228.
    • (2002) Aust N Z J Psychiatry , vol.36 , Issue.2 , pp. 224-228
    • Ritter, A.J.1
  • 17
    • 28144465243 scopus 로고    scopus 로고
    • Safety and immunogenicity of a nicotine conjugate vaccine in current smokers
    • Hatsukami DK, et al. (2005) Safety and immunogenicity of a nicotine conjugate vaccine in current smokers. Clin Pharmacol Ther 78(5):456-467.
    • (2005) Clin Pharmacol Ther , vol.78 , Issue.5 , pp. 456-467
    • Hatsukami, D.K.1
  • 18
    • 0037081517 scopus 로고    scopus 로고
    • Human therapeutic cocaine vaccine: Safety and immunogenicity
    • Kosten TR, et al. (2002) Human therapeutic cocaine vaccine: Safety and immunogenicity. Vaccine 20(7-8):1196-1204.
    • (2002) Vaccine , vol.20 , Issue.7-8 , pp. 1196-1204
    • Kosten, T.R.1
  • 20
    • 0035882744 scopus 로고    scopus 로고
    • Mu opioid receptor-mediated g-protein activation by heroin metabolites: Evidence for greater efficacy of 6-monoacetylmorphine compared with morphine
    • Selley DE, et al. (2001) mu Opioid receptor-mediated G-protein activation by heroin metabolites: Evidence for greater efficacy of 6-monoacetylmorphine compared with morphine. Biochem Pharmacol 62(4):447-455.
    • (2001) Biochem Pharmacol , vol.62 , Issue.4 , pp. 447-455
    • Selley, D.E.1
  • 21
    • 84857729350 scopus 로고    scopus 로고
    • Developing a vaccine against multiple psychoactive targets: A case study of heroin
    • Stowe GN, et al. (2011) Developing a vaccine against multiple psychoactive targets: A case study of heroin. CNS Neurol Disord Drug Targets 10(8):865-875.
    • (2011) CNS Neurol Disord Drug Targets , vol.10 , Issue.8 , pp. 865-875
    • Stowe, G.N.1
  • 22
    • 33645064261 scopus 로고    scopus 로고
    • A novel bivalent morphine/heroin vaccine that prevents relapse to heroin addiction in rodents
    • Anton B, Leff P (2006) A novel bivalent morphine/heroin vaccine that prevents relapse to heroin addiction in rodents. Vaccine 24(16):3232-3240.
    • (2006) Vaccine , vol.24 , Issue.16 , pp. 3232-3240
    • Anton, B.1    Leff, P.2
  • 23
    • 82955247970 scopus 로고    scopus 로고
    • A morphine/heroin vaccine with new hapten design attenuates behavioral effects in rats
    • Li QQ, et al. (2011) A morphine/heroin vaccine with new hapten design attenuates behavioral effects in rats. J Neurochem 119(6):1271-1281.
    • (2011) J Neurochem , vol.119 , Issue.6 , pp. 1271-1281
    • Li, Q.Q.1
  • 24
    • 0016338395 scopus 로고
    • Changes in heroin self-Administration by a rhesus monkey after morphine immunisation
    • Bonese KF, Wainer BH, Fitch FW, Rothberg RM, Schuster CR (1974) Changes in heroin self-Administration by a rhesus monkey after morphine immunisation. Nature 252(5485):708-710.
    • (1974) Nature , vol.252 , Issue.5485 , pp. 708-710
    • Bonese, K.F.1    Wainer, B.H.2    Fitch, F.W.3    Rothberg, R.M.4    Schuster, C.R.5
  • 25
    • 79960649757 scopus 로고    scopus 로고
    • A vaccine strategy that induces protective immunity against heroin
    • Stowe GN, et al. (2011) A vaccine strategy that induces protective immunity against heroin. J Med Chem 54(14):5195-5204.
    • (2011) J Med Chem , vol.54 , Issue.14 , pp. 5195-5204
    • Stowe, G.N.1
  • 26
    • 84872728429 scopus 로고    scopus 로고
    • Selective effects of a morphine conjugate vaccine on heroin and metabolite distribution and heroininduced behaviors in rats
    • Raleigh MD, Pravetoni M, Harris AC, Birnbaum AK, Pentel PR (2013) Selective effects of a morphine conjugate vaccine on heroin and metabolite distribution and heroininduced behaviors in rats. J Pharmacol Exp Ther 344(2):397-406.
    • (2013) J Pharmacol Exp Ther , vol.344 , Issue.2 , pp. 397-406
    • Raleigh, M.D.1    Pravetoni, M.2    Harris, A.C.3    Birnbaum, A.K.4    Pentel, P.R.5
  • 27
    • 33645509739 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacokinetic variability of heroin and its metabolites: Review of the literature
    • Rook EJ, Huitema AD, van den Brink W, van Ree JM, Beijnen JH (2006) Pharmacokinetics and pharmacokinetic variability of heroin and its metabolites: Review of the literature. Curr Clin Pharmacol 1(1):109-118.
    • (2006) Curr Clin Pharmacol , vol.1 , Issue.1 , pp. 109-118
    • Rook, E.J.1    Huitema, A.D.2    Van Den Brink, W.3    Van Ree, J.M.4    Beijnen, J.H.5
  • 28
    • 33645107718 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of high doses of pharmaceutically prepared heroin, by intravenous or by inhalation route in opioiddependent patients
    • Rook EJ, et al. (2006) Pharmacokinetics and pharmacodynamics of high doses of pharmaceutically prepared heroin, by intravenous or by inhalation route in opioiddependent patients. Basic Clin Pharmacol Toxicol 98(1):86-96.
    • (2006) Basic Clin Pharmacol Toxicol , vol.98 , Issue.1 , pp. 86-96
    • Rook, E.J.1
  • 29
    • 0025032241 scopus 로고
    • Species differences in metabolism of codeine: Urinary excretion of codeine glucuronide, morphine-3-glucuronide and morphine-6-glucuronide in mice, rats, guinea pigs and rabbits
    • Oguri K, Hanioka N, Yoshimura H (1990) Species differences in metabolism of codeine: Urinary excretion of codeine glucuronide, morphine-3-glucuronide and morphine-6-glucuronide in mice, rats, guinea pigs and rabbits. Xenobiotica 20(7): 683-688.
    • (1990) Xenobiotica , vol.20 , Issue.7 , pp. 683-688
    • Oguri, K.1    Hanioka, N.2    Yoshimura, H.3
  • 30
    • 77951884731 scopus 로고    scopus 로고
    • Yohimbine stress potentiates conditioned cue-induced reinstatement of heroin-seeking in rats
    • Banna KM, Back SE, Do P, See RE (2010) Yohimbine stress potentiates conditioned cue-induced reinstatement of heroin-seeking in rats. Behav Brain Res 208(1):144-148.
    • (2010) Behav Brain Res , vol.208 , Issue.1 , pp. 144-148
    • Banna, K.M.1    Back, S.E.2    Do, P.3    See, R.E.4
  • 31
    • 36249016353 scopus 로고    scopus 로고
    • Differential effects of blockade of dopamine d1-family receptors in nucleus accumbens core or shell on reinstatement of heroin seeking induced by contextual and discrete cues
    • Bossert JM, Poles GC, Wihbey KA, Koya E, Shaham Y (2007) Differential effects of blockade of dopamine D1-family receptors in nucleus accumbens core or shell on reinstatement of heroin seeking induced by contextual and discrete cues. J Neurosci 27(46):12655-12663.
    • (2007) J Neurosci , vol.27 , Issue.46 , pp. 12655-12663
    • Bossert, J.M.1    Poles, G.C.2    Wihbey, K.A.3    Koya, E.4    Shaham, Y.5
  • 32
    • 33847011780 scopus 로고    scopus 로고
    • Heroin-induced reinstatement is specific to compulsive heroin use and dissociable from heroin reward and sensitization
    • Lenoir M, Ahmed SH (2007) Heroin-induced reinstatement is specific to compulsive heroin use and dissociable from heroin reward and sensitization. Neuropsychopharmacology 32(3):616-624.
    • (2007) Neuropsychopharmacology , vol.32 , Issue.3 , pp. 616-624
    • Lenoir, M.1    Ahmed, S.H.2
  • 33
    • 33748272362 scopus 로고    scopus 로고
    • Unlimited access to heroin self-Administration: Independent motivational markers of opiate dependence
    • Chen SA, et al. (2006) Unlimited access to heroin self-Administration: Independent motivational markers of opiate dependence. Neuropsychopharmacology 31(12): 2692-2707.
    • (2006) Neuropsychopharmacology , vol.31 , Issue.12 , pp. 2692-2707
    • Chen, S.A.1
  • 34
    • 79953250110 scopus 로고    scopus 로고
    • Escalation patterns of varying periods of heroin access
    • Vendruscolo LF, et al. (2011) Escalation patterns of varying periods of heroin access. Pharmacol Biochem Behav 98(4):570-574.
    • (2011) Pharmacol Biochem Behav , vol.98 , Issue.4 , pp. 570-574
    • Vendruscolo, L.F.1
  • 35
    • 0021322009 scopus 로고
    • Effects of opiate antagonists and their quaternary derivatives on heroin self-Administration in the rat
    • Koob GF, Pettit HO, Ettenberg A, Bloom FE (1984) Effects of opiate antagonists and their quaternary derivatives on heroin self-Administration in the rat. J Pharmacol Exp Ther 229(2):481-486.
    • (1984) J Pharmacol Exp Ther , vol.229 , Issue.2 , pp. 481-486
    • Koob, G.F.1    Pettit, H.O.2    Ettenberg, A.3    Bloom, F.E.4
  • 36
    • 84864742914 scopus 로고    scopus 로고
    • Craving correlates with mesolimbic responses to heroin-related cues in short-term abstinence from heroin: An event-related fmri study
    • Li Q, et al. (2012) Craving correlates with mesolimbic responses to heroin-related cues in short-term abstinence from heroin: An event-related fMRI study. Brain Res 1469: 63-72.
    • (2012) Brain Res , vol.1469 , pp. 63-72
    • Li, Q.1
  • 37
    • 39149106754 scopus 로고    scopus 로고
    • Striatal dopamine d2 receptor binding and dopamine release during cue-elicited craving in recently abstinent opiate-dependent males
    • Zijlstra F, Booij J, van den Brink W, Franken IH (2008) Striatal dopamine D2 receptor binding and dopamine release during cue-elicited craving in recently abstinent opiate-dependent males. Eur Neuropsychopharmacol 18(4):262-270.
    • (2008) Eur Neuropsychopharmacol , vol.18 , Issue.4 , pp. 262-270
    • Zijlstra, F.1    Booij, J.2    Van Den Brink, W.3    Franken, I.H.4
  • 38
  • 39
    • 84858661736 scopus 로고    scopus 로고
    • An oxycodone conjugate vaccine elicits drug-specific antibodies that reduce oxycodone distribution to brain and hot-plate analgesia
    • Pravetoni M, et al. (2012) An oxycodone conjugate vaccine elicits drug-specific antibodies that reduce oxycodone distribution to brain and hot-plate analgesia. J Pharmacol Exp Ther 341(1):225-232.
    • (2012) J Pharmacol Exp Ther , vol.341 , Issue.1 , pp. 225-232
    • Pravetoni, M.1
  • 40
    • 84873905113 scopus 로고    scopus 로고
    • Reduced antinociception of opioids in rats and mice by vaccination with immunogens containing oxycodone and hydrocodone haptens
    • Pravetoni M, et al. (2013) Reduced antinociception of opioids in rats and mice by vaccination with immunogens containing oxycodone and hydrocodone haptens. J Med Chem 56(3):915-923.
    • (2013) J Med Chem , vol.56 , Issue.3 , pp. 915-923
    • Pravetoni, M.1
  • 41
    • 84861982138 scopus 로고    scopus 로고
    • Co-Administration of morphine and oxycodone vaccines reduces the distribution of 6-monoacetylmorphine and oxycodone to brain in rats
    • Pravetoni M, et al. (2012) Co-Administration of morphine and oxycodone vaccines reduces the distribution of 6-monoacetylmorphine and oxycodone to brain in rats. Vaccine 30(31):4617-4624.
    • (2012) Vaccine , vol.30 , Issue.31 , pp. 4617-4624
    • Pravetoni, M.1
  • 42
    • 0018867072 scopus 로고
    • Efficient analysis of experimental observations
    • Dixon WJ (1980) Efficient analysis of experimental observations. Annu Rev Pharmacol Toxicol 20:441-462.
    • (1980) Annu Rev Pharmacol Toxicol , vol.20 , pp. 441-462
    • Dixon, W.J.1
  • 43
    • 70349301428 scopus 로고    scopus 로고
    • Determination of heroin and its main metabolites in small sample volumes of whole blood and brain tissue by reversed-phase liquid chromatography-tandem mass spectrometry
    • Karinen R, et al. (2009) Determination of heroin and its main metabolites in small sample volumes of whole blood and brain tissue by reversed-phase liquid chromatography-tandem mass spectrometry. J Anal Toxicol 33(7):345-350.
    • (2009) J Anal Toxicol , vol.33 , Issue.7 , pp. 345-350
    • Karinen, R.1
  • 44
    • 11144275200 scopus 로고    scopus 로고
    • Buprenorphine and a crf1 antagonist block the acquisition of opiate withdrawal-induced conditioned place aversion in rats
    • Stinus L, Cador M, Zorrilla EP, Koob GF (2005) Buprenorphine and a CRF1 antagonist block the acquisition of opiate withdrawal-induced conditioned place aversion in rats. Neuropsychopharmacology 30(1):90-98.
    • (2005) Neuropsychopharmacology , vol.30 , Issue.1 , pp. 90-98
    • Stinus, L.1    Cador, M.2    Zorrilla, E.P.3    Koob, G.F.4
  • 45
    • 0027194404 scopus 로고
    • Modulation of cocaine self-Administration in the rat through d-3 dopamine receptors
    • Caine SB, Koob GF (1993) Modulation of cocaine self-Administration in the rat through D-3 dopamine receptors. Science 260(5115):1814-1816.
    • (1993) Science , vol.260 , Issue.5115 , pp. 1814-1816
    • Caine, S.B.1    Koob, G.F.2


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