메뉴 건너뛰기




Volumn 12, Issue 1, 2012, Pages 67-72

Vaccines targeting drugs of abuse: Is the glass half-empty or half-full?

Author keywords

[No Author keywords available]

Indexed keywords

ALUMINUM SALT; AMPHETAMINE; BENZODIAZEPINE; CARBOHYDRATE; CARRIER PROTEIN; CHOLERA TOXIN B SUBUNIT; COCAINE; CYTOKINE; HEMOCYANIN; LIPOSOME; MONOCLONAL ANTIBODY; MORPHINE; NICOTINE; PHENCYCLIDINE; VACCINE;

EID: 84655167585     PISSN: 14741733     EISSN: 14741741     Source Type: Journal    
DOI: 10.1038/nri3130     Document Type: Review
Times cited : (36)

References (60)
  • 1
    • 79960649757 scopus 로고    scopus 로고
    • A vaccine strategy that induces protective immunity against heroin
    • Stowe, G. N. et al. A vaccine strategy that induces protective immunity against heroin. J. Med. Chem. 54, 5195-5204 (2011).
    • (2011) J. Med. Chem. , vol.54 , pp. 5195-5204
    • Stowe, G.N.1
  • 2
    • 77957361348 scopus 로고    scopus 로고
    • Development trends for human monoclonal antibody therapeutics
    • Nelson, A. L., Dhimolea, E. & Reichert, J. M. Development trends for human monoclonal antibody therapeutics. Nature Rev. Drug Discov. 9, 767-774 (2010).
    • (2010) Nature Rev. Drug Discov. , vol.9 , pp. 767-774
    • Nelson, A.L.1    Dhimolea, E.2    Reichert, J.M.3
  • 3
    • 70349504135 scopus 로고    scopus 로고
    • Vaccines against morphine/heroin and its use as effective medication for preventing relapse to opiate addictive behaviors
    • Anton, B. et al. Vaccines against morphine/heroin and its use as effective medication for preventing relapse to opiate addictive behaviors. Hum. Vaccin. 5, 214-229 (2009).
    • (2009) Hum. Vaccin. , vol.5 , pp. 214-229
    • Anton, B.1
  • 5
    • 70349507294 scopus 로고    scopus 로고
    • Vaccines against nicotine
    • Cerny, E. H. & Cerny, T. Vaccines against nicotine. Hum. Vaccin. 5, 200-205 (2009).
    • (2009) Hum. Vaccin. , vol.5 , pp. 200-205
    • Cerny, E.H.1    Cerny, T.2
  • 6
    • 71349084953 scopus 로고    scopus 로고
    • Cocaine-specific antibodies blunt the subjective effects of smoked cocaine in humans
    • Haney, M., Gunderson, E. W., Jiang, H., Collins, E. D. & Foltin, R. W. Cocaine-specific antibodies blunt the subjective effects of smoked cocaine in humans. Biol. Psychiatry 67, 59-65 (2010).
    • (2010) Biol. Psychiatry , vol.67 , pp. 59-65
    • Haney, M.1    Gunderson, E.W.2    Jiang, H.3    Collins, E.D.4    Foltin, R.W.5
  • 11
    • 36649019572 scopus 로고    scopus 로고
    • Engineering and characterization of a mouse/human chimeric anti-phencyclidine monoclonal antibody
    • DOI 10.1016/j.intimp.2007.09.020, PII S1567576907003086
    • Lacy, H. M., Gunnell, M. G., Laurenzana, E. M. & Owens, S. M. Engineering and characterization of a mouse/human chimeric anti-phencyclidine monoclonal antibody. Int. Immunopharmacol. 8, 1-11 (2008). (Pubitemid 350199094)
    • (2008) International Immunopharmacology , vol.8 , Issue.1 , pp. 1-11
    • Lacy, H.M.1    Gunnell, M.G.2    Laurenzana, E.M.3    Owens, S.M.4
  • 14
    • 0022598189 scopus 로고
    • Phencyclidine-specific Fab fragments alter phencyclidine disposition in dogs
    • Owens, S. M. & Mayersohn, M. Phencyclidine-specific Fab fragments alter phencyclidine disposition in dogs. Drug Metab. Dispos. 14, 52-58 (1986). (Pubitemid 16152314)
    • (1986) Drug Metabolism and Disposition , vol.14 , Issue.1 , pp. 52-58
    • Owens, S.M.1    Mayersohn, M.2
  • 19
    • 0034050543 scopus 로고    scopus 로고
    • Exploring the feasibility of an anti-idiotypic cocaine vaccine: Analysis of the specificity of anticocaine antibodies (Ab1) capable of inducing Ab2β anti-idiotypic antibodies
    • DOI 10.1046/j.1365-2567.2000.00004.x
    • Schabacker, D. S., Kirschbaum, K. S. & Segre, M. Exploring the feasibility of an anti-idiotypic cocaine vaccine: analysis of the specificity of anticocaine antibodies (Ab1) capable of inducing Ab2β anti-idiotypic antibodies. Immunology 100, 48-56 (2000). (Pubitemid 30242881)
    • (2000) Immunology , vol.100 , Issue.1 , pp. 48-56
    • Schabacker, D.S.1    Kirschbaum, K.S.2    Segre, M.3
  • 20
    • 79952612830 scopus 로고    scopus 로고
    • Immunopharmacotherapeutic manifolds and modulation of cocaine overdose
    • Treweek, J. B., Roberts, A. J. & Janda, K. D. Immunopharmacotherapeutic manifolds and modulation of cocaine overdose. Pharmacol. Biochem. Behav. 98, 474-484 (2011).
    • (2011) Pharmacol. Biochem. Behav. , vol.98 , pp. 474-484
    • Treweek, J.B.1    Roberts, A.J.2    Janda, K.D.3
  • 21
    • 33646792942 scopus 로고    scopus 로고
    • Anti-phencyclidine monoclonal antibody binding capacity is not the only determinant of effectiveness, disproving the concept that antibody capacity is easily surmounted
    • DOI 10.1124/dmd.105.005934
    • Pitas, G., Laurenzana, E. M., Williams, D. K., Owens, S. M. & Gentry, W. B. Anti-phencyclidine monoclonal antibody binding capacity is not the only determinant of effectiveness, disproving the concept that antibody capacity is easily surmounted. Drug Metab. Dispos. 34, 906-912 (2006). (Pubitemid 43763745)
    • (2006) Drug Metabolism and Disposition , vol.34 , Issue.6 , pp. 906-912
    • Pitas, G.1    Laurenzana, E.M.2    Williams, D.K.3    Owens, S.M.4    Gentry, W.B.5
  • 22
    • 0035878160 scopus 로고    scopus 로고
    • An immunoassay for small analytes with theoretical detection limits
    • DOI 10.1021/ac001328d
    • Ohmura, N., Lackie, S. J. & Saiki, H. An immunoassay for small analytes with theoretical detection limits. Anal. Chem. 73, 3392-3399 (2001). (Pubitemid 32880624)
    • (2001) Analytical Chemistry , vol.73 , Issue.14 , pp. 3392-3399
    • Ohmura, N.1    Lackie, S.J.2    Saiki, H.3
  • 23
    • 0346731232 scopus 로고    scopus 로고
    • Three-Dimensional Quantitative Structure-Activity Relationship Modeling of Cocaine Binding by a Novel Human Monoclonal Antibody
    • DOI 10.1021/jm030351z
    • Paula, S., Tabet, M. R., Farr, C. D., Norman, A. B. & Ball, W. J. J. Three-dimensional quantitative structure-activity relationship modeling of cocaine binding by a novel human monoclonal antibody. J. Med. Chem. 47, 133-142 (2004). (Pubitemid 38040497)
    • (2004) Journal of Medicinal Chemistry , vol.47 , Issue.1 , pp. 133-142
    • Paula, S.1    Tabet, M.R.2    Farr, C.D.3    Norman, A.B.4    Ball Jr., W.J.5
  • 24
    • 0028238389 scopus 로고
    • Anti-phencyclidine monoclonal Fab fragments markedly alter phencyclidine pharmacokinetics in rats
    • Valentine, J. L., Arnold, L. W. & Owens, S. M. Anti-phencyclidine monoclonal Fab fragments markedly alter phencyclidine pharmacokinetics in rats. J. Pharmacol. Exp. Ther. 269, 1079-1085 (1994). (Pubitemid 24204188)
    • (1994) Journal of Pharmacology and Experimental Therapeutics , vol.269 , Issue.3 , pp. 1079-1085
    • Valentine, J.L.1    Arnold, L.W.2    Owens, S.M.3
  • 25
    • 0022481396 scopus 로고
    • 2, and Fab' in mice
    • Covell, D. G. et al. Pharmacokinetics of monoclonal immunoglobulin G1, F(ab')2, and Fab' in mice. Cancer Res. 46, 3969-3978 (1986). (Pubitemid 16075893)
    • (1986) Cancer Research , vol.46 , Issue.8 , pp. 3969-3978
    • Covell, D.G.1    Barbet, J.2    Holton, O.D.3
  • 26
    • 27144432842 scopus 로고    scopus 로고
    • Engineered antibody fragments and the rise of single domains
    • DOI 10.1038/nbt1142, PII N1142
    • Holliger, P. & Hudson, P. J. Engineered antibody fragments and the rise of single domains. Nature Biotech. 23, 1126-1136 (2005). (Pubitemid 41486394)
    • (2005) Nature Biotechnology , vol.23 , Issue.9 , pp. 1126-1136
    • Holliger, P.1    Hudson, P.J.2
  • 27
  • 28
    • 0030426269 scopus 로고    scopus 로고
    • Antiphencyclidine monoclonal antibody therapy significantly changes phencyclidine concentrations in brain and other tissues in rats
    • Valentine, J. L. & Owens, S. M. Antiphencyclidine monoclonal antibody therapy significantly changes phencyclidine concentrations in brain and other tissues in rats. J. Pharmacol. Exp. Ther. 278, 717-724 (1996). (Pubitemid 27167038)
    • (1996) Journal of Pharmacology and Experimental Therapeutics , vol.278 , Issue.2 , pp. 717-724
    • Valentine, J.L.1    Owens, S.M.2
  • 29
    • 0034097138 scopus 로고    scopus 로고
    • Anti-phencyclidine monoclonal antibodies provide long-term reductions in brain phencyclidine concentrations during chronic phencyclidine administration in rats
    • Proksch, J. W., Gentry, W. B. & Owens, S. M. Anti-phencyclidine monoclonal antibodies provide long-term reductions in brain phencyclidine concentrations during chronic phencyclidine administration in rats. J. Pharmacol. Exp. Ther. 292, 831-837 (2000). (Pubitemid 30136572)
    • (2000) Journal of Pharmacology and Experimental Therapeutics , vol.292 , Issue.3 , pp. 831-837
    • Proksch, J.W.1    Gentry, W.B.2    Owens, S.M.3
  • 30
    • 0030030677 scopus 로고    scopus 로고
    • Effects of recombinant drug-specific single chain antibody Fv fragment on [3H]-desipramine distribution in rats
    • Shelver, W. L. et al. Effects of recombinant drug-specific single chain antibody Fv fragment on [3H]-desipramine distribution in rats. Biochem. Pharmacol. 51, 531-537 (1996).
    • (1996) Biochem. Pharmacol. , vol.51 , pp. 531-537
    • Shelver, W.L.1
  • 31
    • 0028951604 scopus 로고
    • Effects of specific antibody Fab fragments on desipramine pharmacokinetics in the rat in vivo and in the isolated perfused liver
    • Keyler, D. E., Le Couteur, D. G., Pond, S. M., St. Peter, J. V. & Pentel, P. R. Effects of specific antibody Fab fragments on desipramine pharmacokinetics in the rat in vivo and in the isolated, perfused liver. J. Pharmacol. Exp. Ther. 272, 1117-1123 (1995).
    • (1995) J. Pharmacol. Exp. Ther. , vol.272 , pp. 1117-1123
    • Keyler, D.E.1    Le Couteur, D.G.2    Pond, S.M.3    St. Peter, J.V.4    Pentel, P.R.5
  • 32
    • 0017325163 scopus 로고
    • Effects of digoxin-specific antibodies and their Fab fragments on digoxin pharmacokinetics in dogs
    • Butler, V. P. J. et al. Effects of digoxin-specific antibodies and their Fab fragments on digoxin pharmacokinetics in dogs. J. Clin. Invest. 59, 345-359 (1977).
    • (1977) J. Clin. Invest. , vol.59 , pp. 345-359
    • Butler, V.P.J.1
  • 33
    • 0024384356 scopus 로고
    • Immunotoxicotherapy: Present status and future trends
    • Scherrmann, J. M. et al. Immunotoxicotherapy: present status and future trends. J. Toxicol. Clin. Toxicol. 27, 1-35 (1989).
    • (1989) J. Toxicol. Clin. Toxicol. , vol.27 , pp. 1-35
    • Scherrmann, J.M.1
  • 34
    • 0024293979 scopus 로고
    • Single-chain antigen-binding proteins
    • Bird, R. E. et al. Single-chain antigen-binding proteins. Science 242, 423-426 (1988).
    • (1988) Science , vol.242 , pp. 423-426
    • Bird, R.E.1
  • 35
    • 0023639244 scopus 로고
    • Biodistribution of monoclonal IgG1, F(ab') 2, and Fab' in mice after intravenous injection. Comparison between anti-B cell (anti-Lyb8.2) and irrelevant (MOPC-21) antibodies
    • Holton, O. D. et al. Biodistribution of monoclonal IgG1, F(ab')2, and Fab' in mice after intravenous injection. Comparison between anti-B cell (anti-Lyb8.2) and irrelevant (MOPC-21) antibodies. J. Immunol. 139, 3041-3049 (1987).
    • (1987) J. Immunol. , vol.139 , pp. 3041-3049
    • Holton, O.D.1
  • 36
    • 49649104752 scopus 로고    scopus 로고
    • A vaccine against nicotine for smoking cessation: A randomized controlled trial
    • Cornuz, J. et al. A vaccine against nicotine for smoking cessation: a randomized controlled trial. PLoS ONE 3, e2547 (2008).
    • (2008) PLoS ONE , vol.3
    • Cornuz, J.1
  • 37
    • 70349690285 scopus 로고    scopus 로고
    • Cocaine vaccine for the treament of cocaine dependence: A randomized double-blind placebo-controlled efficacy trial
    • Martell, B. A. et al. Cocaine vaccine for the treament of cocaine dependence: a randomized double-blind placebo-controlled efficacy trial. Arch. Gen. Psychiatry 66, 1116-1123 (2009).
    • (2009) Arch. Gen. Psychiatry , vol.66 , pp. 1116-1123
    • Martell, B.A.1
  • 38
    • 0001815978 scopus 로고
    • Immunological notes. XXIII. The antigenic value of toxoid precipitated by potassium alum
    • Glenny, A. T., Pope, C. G., Waddington, H. & Wallace, U. Immunological notes. XXIII. The antigenic value of toxoid precipitated by potassium alum. J. Pathol. Bacteriol. 29, 38-39 (1926).
    • (1926) J. Pathol. Bacteriol. , vol.29 , pp. 38-39
    • Glenny, A.T.1    Pope, C.G.2    Waddington, H.3    Wallace, U.4
  • 39
    • 0024328379 scopus 로고
    • Different T helper cell subsets elicited in mice utilizing two different adjuvant vehicles: The role of endogenous interleukin 1 in proliferative responses
    • DOI 10.1016/0008-8749(89)90011-7
    • Grun, J. L. & Maurer, P. H. Different T helper cell subsets elicited in mice utilising two different adjuvant vehicles: the role of endogenous IL-1 in proliferative responses. Cell. Immunol. 121, 134-145 (1989). (Pubitemid 19160191)
    • (1989) Cellular Immunology , vol.121 , Issue.1 , pp. 134-145
    • Grun, J.L.1    Maurer, P.H.2
  • 40
    • 77955597687 scopus 로고    scopus 로고
    • Unmet needs in modern vaccinology: Adjuvants to improve the immune response
    • Leroux-Roels, G. Unmet needs in modern vaccinology: adjuvants to improve the immune response. Vaccine 28, C25-C36 (2010).
    • (2010) Vaccine , vol.28
    • Leroux-Roels, G.1
  • 41
    • 2942701975 scopus 로고    scopus 로고
    • Promotion of B cell immune responses via an alum-induced myeloid cell population
    • DOI 10.1126/science.1089926
    • Jordan, M. B., Mills, D. M., Kappler, J., Marrack, P. & Cambier, J. C. Promotion of B cell immune responses via an alum-induced myeloid cell population. Science 304, 1808-1810 (2004). (Pubitemid 38787898)
    • (2004) Science , vol.304 , Issue.5678 , pp. 1808-1810
    • Jordan, M.B.1    Mills, D.M.2    Kappler, J.3    Marrack, P.4    Cambier, J.C.5
  • 42
    • 27744440480 scopus 로고    scopus 로고
    • (How) do aluminium adjuvants work?
    • DOI 10.1016/j.imlet.2005.08.002, PII S0165247805001872
    • Brewer, J. M. (How) do aluminium adjuvants work? Immunol. Lett. 102, 10-15 (2006). (Pubitemid 41606034)
    • (2006) Immunology Letters , vol.102 , Issue.1 , pp. 10-15
    • Brewer, J.M.1
  • 45
    • 4644318756 scopus 로고    scopus 로고
    • Adenoviruses as vaccine vectors
    • DOI 10.1016/j.ymthe.2004.07.013, PII S1525001604013425
    • Tatsis, N. & Ertl, H. C. Adenoviruses as vaccine vectors. Mol. Ther. 10, 616-629 (2004). (Pubitemid 39272851)
    • (2004) Molecular Therapy , vol.10 , Issue.4 , pp. 616-629
    • Tatsis, N.1    Ertl, H.C.2
  • 47
    • 79952195569 scopus 로고    scopus 로고
    • Cocaine analog coupled to disrupted adenovirus: A vaccine strategy to evoke high-titer immunity against addictive drugs
    • Hicks, M. J. et al. Cocaine analog coupled to disrupted adenovirus: a vaccine strategy to evoke high-titer immunity against addictive drugs. Mol. Ther. 19, 612-619 (2011).
    • (2011) Mol. Ther. , vol.19 , pp. 612-619
    • Hicks, M.J.1
  • 48
    • 0034047840 scopus 로고    scopus 로고
    • Ten commandments: Lessons from the enzymology of DNA replication
    • DOI 10.1128/JB.182.13.3613-3618.2000
    • Kornberg, A. Ten commandments: lessons from the enzymology of DNA replication J. Bacteriol. 182, 3613-3618 (2000). (Pubitemid 30413008)
    • (2000) Journal of Bacteriology , vol.182 , Issue.13 , pp. 3613-3618
    • Kornberg, A.1
  • 50
    • 77950589619 scopus 로고    scopus 로고
    • A critical evaluation of a nicotine vaccine within a self-administration behavioral model
    • Moreno, A. Y. et al. A critical evaluation of a nicotine vaccine within a self-administration behavioral model. Mol. Pharm. 7, 431-441 (2010).
    • (2010) Mol. Pharm. , vol.7 , pp. 431-441
    • Moreno, A.Y.1
  • 51
    • 79951813724 scopus 로고    scopus 로고
    • Immunogenicity and smoking-cessation outcomes for a novel nicotine immunotherapeutic
    • Hatsukami, D. K. et al. Immunogenicity and smoking-cessation outcomes for a novel nicotine immunotherapeutic. Clin. Pharmacol. Ther. 89, 392-399 (2011).
    • (2011) Clin. Pharmacol. Ther. , vol.89 , pp. 392-399
    • Hatsukami, D.K.1
  • 52
    • 0027998798 scopus 로고
    • Enhanced immunogenicity of protein-dextran conjugates: I. Rapid stimulation of enhanced antibody responses to poorly immunogenic molecules
    • DOI 10.1016/0264-410X(94)90237-2
    • Lees, A. et al. Enhanced immunogenicity of protein-dextran conjugates: I. Rapid stimulation of enhanced antibody responses to poorly immunogenic molecules. Vaccine 12, 1160-1166 (1994). (Pubitemid 24293234)
    • (1994) Vaccine , vol.12 , Issue.13 , pp. 1160-1166
    • Lees, A.1    Finkelman, F.2    Inman, J.K.3    Witherspoon, K.4    Johnson, P.5    Kennedy, J.6    Mond, J.J.7
  • 53
    • 7044247194 scopus 로고    scopus 로고
    • Ethical quagmire awaits vaccine for cocaine addiction
    • Katsnelson, A. Ethical quagmire awaits vaccine for cocaine addiction. Nature Med. 10, 1007 (2004). (Pubitemid 39424848)
    • (2004) Nature Medicine , vol.10 , Issue.10 , pp. 1007
    • Katsnelson, A.1
  • 54
    • 0030834855 scopus 로고    scopus 로고
    • Immunization for prevention and treatment of cocaine abuse: Legal and ethical implications
    • DOI 10.1016/S0376-8716(97)00075-6, PII S0376871697000756
    • Cohen, P. J. Immunization for prevention and treatment of cocaine abuse: legal and ethical implications. Drug Alcohol Depend. 48, 167-174 (1997). (Pubitemid 27526023)
    • (1997) Drug and Alcohol Dependence , vol.48 , Issue.3 , pp. 167-174
    • Cohen, P.J.1
  • 57
    • 77957904093 scopus 로고    scopus 로고
    • Substance Abuse and Mental Health Services Administration Summary of National Findings [online]
    • Substance Abuse and Mental Health Services Administration. Results from the 2009 National Survey on Drug Use and Health: Volume I. Summary of National Findings [online], http://www.oas.samhsa. gov/NSDUH/2k9NSDUH/2k9Results.htm (2010).
    • (2010) Results from the 2009 National Survey on Drug Use and Health: Volume I.
  • 58
    • 9444239833 scopus 로고    scopus 로고
    • Inulin-derived adjuvants efficiently promote both Th1 and Th2 immune responses
    • DOI 10.1111/j.1440-1711.2004.01290.x
    • Silva, D. G., Cooper, P. D. & Petrovsky, N. Inulin-derived adjuvants efficiently promote both Th1 and Th2 immune responses. Immunol. Cell Biol. 82, 611-616 (2004). (Pubitemid 39563962)
    • (2004) Immunology and Cell Biology , vol.82 , Issue.6 , pp. 611-616
    • Silva, D.G.1    Cooper, P.D.2    Petrovsky, N.3
  • 59
    • 0031020339 scopus 로고    scopus 로고
    • Adjuvant modulation of immune responses to tuberculosis subunit vaccines
    • Lindblad, E. B., Elhay, M. J., Silva, R., Appelberg, R. & Andersen, P. Adjuvant modulation of immune responses to tuberculosis subunit vaccines. Infect. Immun. 65, 623-629 (1997). (Pubitemid 27053234)
    • (1997) Infection and Immunity , vol.65 , Issue.2 , pp. 623-629
    • Lindblad, E.B.1    Elhay, M.J.2    Silva, R.3    Appelberg, R.4    Andersen, P.5
  • 60
    • 4243187214 scopus 로고    scopus 로고
    • Aluminium adjuvants-in retrospect and prospect
    • Lindblad, E. B. Aluminium adjuvants-in retrospect and prospect. Vaccine 22, 3658-3668 (2004).
    • (2004) Vaccine , vol.22 , pp. 3658-3668
    • Lindblad, E.B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.