Modulating cocaine vaccine potency through hapten fluorination

Journal of the American Chemical Society

Volumn 135, Issue 8, 2013, Pages 2971-2974

  Cai, Xiaoqing ^a   Tsuchikama, Kyoji ^a   Janda, Kim D ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; ANTIGENS; FLUORINATION; HALOGENATION; SCAFFOLDS;

CLINICAL TRIAL; COCAINE ADDICTION; DRUGS OF ABUSE; IMMUNOLOGICAL PROPERTIES; LONG LASTING; NEW APPROACHES; PARENT STRUCTURE;

VACCINES;

CHLORINE; COCAINE; COCAINE DERIVATIVE; COCAINE VACCINE; FLUORINE; HAPTEN; IMMUNOGLOBULIN G; MOLECULAR SCAFFOLD; SUCCINYL NORCOCAINE; UNCLASSIFIED DRUG; VACCINE;

ACTIVE IMMUNIZATION; ANIMAL EXPERIMENT; ANTIBODY BLOOD LEVEL; ANTIBODY RESPONSE; ANTIBODY SPECIFICITY; ANTIGEN BINDING; ANTIGEN RECOGNITION; ARTICLE; COCAINE DEPENDENCE; CONTROLLED STUDY; DRUG DESIGN; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; FLUORINATION; IMMUNOGENICITY; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOSTIMULATION; MOUSE; NONHUMAN; VACCINATION;

EID: 84874589023     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja400356g     Document Type: Article

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