Increasing leucine concentration stimulates mechanistic target of rapamycin signaling and cell growth in C2C12 skeletal muscle cells

Nutrition Research

Volumn 34, Issue 11, 2014, Pages 1000-1007

  Areta, José L ^a   Hawley, John A ^a,b   Ye, Ji Ming ^a   Chan, M H Stanley ^a   Coffey, Vernon G ^c  

^a RMIT UNIVERSITY   (Australia)

^b LIVERPOOL JOHN MOORES UNIVERSITY   (United Kingdom)

^c QUEENSLAND UNIVERSITY OF TECHNOLOGY   (Australia)

Author keywords

Amino acids; Anabolic signaling; C2C12; mTOR; Protein synthesis; Skeletal muscle

Indexed keywords

ELONGATION FACTOR 2; INITIATION FACTOR 2ALPHA; INITIATION FACTOR 4E BINDING PROTEIN 1; LEUCINE; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN S6; S6 KINASE; CARRIER PROTEIN; EIF4EBP1 PROTEIN, MOUSE; MTOR PROTEIN, MOUSE; PHOSPHOPROTEIN; PROLINE-RICH AKT SUBSTRATE, 40 KDA PROTEIN, MOUSE; RIBOSOMAL PROTEIN S6, MOUSE; TARGET OF RAPAMYCIN KINASE;

ARTICLE; CELL GROWTH; CELL SIZE; CONCENTRATION RESPONSE; CONTROLLED STUDY; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; TRANSLATION INITIATION; ANIMAL; BLOOD; CELL LINE; CYTOLOGY; DOSE RESPONSE; DRUG EFFECTS; GENETICS; METABOLISM; MOUSE; PHOSPHORYLATION;

ANIMALS; CARRIER PROTEINS; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; LEUCINE; MICE; MUSCLE FIBERS, SKELETAL; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN BIOSYNTHESIS; RIBOSOMAL PROTEIN S6; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84922397301     PISSN: 02715317     EISSN: 18790739     Source Type: Journal    
DOI: 10.1016/j.nutres.2014.09.011     Document Type: Article

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