Targeted therapy for allergic diseases: At the intersection of cutting-edge science and clinical practice

Journal of Allergy and Clinical Immunology

Volumn 135, Issue 2, 2015, Pages 354-356

  Boguniewicz, Mark ^a   Leung, Donald Y M ^a  

^a University of Colorado Denver and Children s Hospital Colorado   (United States)

Author keywords

allergic diseases; asthma; atopic dermatitis; biologic therapy; dupilumab; food allergy; mAb therapy; omalizumab; psoriasis

Indexed keywords

CYCLOSPORIN; DUPILUMAB; IMMUNOGLOBULIN E; MEPOLIZUMAB; OMALIZUMAB; PLACEBO; THYMIC STROMAL LYMPHOPOIETIN;

AIRWAY RESISTANCE; ALLERGIC ASTHMA; ALLERGIC DISEASE; ATOPIC DERMATITIS; BIOLOGICAL THERAPY; CAREGIVER; CHRONIC RHINOSINUSITIS; CHRONIC URTICARIA; CLINICAL PRACTICE; CLINICAL RESEARCH; COHORT ANALYSIS; DRUG EFFICACY; DRUG SAFETY; EOSINOPHIL COUNT; EOSINOPHILIC ESOPHAGITIS; FOLLOW UP; FOOD ALLERGY; FOOD AND DRUG ADMINISTRATION; GENE EXPRESSION PROFILING; HIGH RISK PATIENT; HUMAN; HYPEREOSINOPHILIC SYNDROME; IMMUNE DYSREGULATION; LUNG LAVAGE; MACACA FASCICULARIS; NATIONAL HEALTH ORGANIZATION; NONHUMAN; NOSE POLYP; OBSERVATIONAL STUDY; PALLIATIVE THERAPY; PEANUT ALLERGY; PHASE 3 CLINICAL TRIAL (TOPIC); PRACTICE GUIDELINE; PRIORITY JOURNAL; PSORIASIS; REVIEW; SELF EVALUATION; SYSTEMIC THERAPY; ANIMAL; HYPERSENSITIVITY; IMMUNOLOGY; MOLECULARLY TARGETED THERAPY;

ANIMALS; HUMANS; HYPERSENSITIVITY; MOLECULAR TARGETED THERAPY;

EID: 84922387096     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2014.12.1907     Document Type: Editorial

References (23)

1. G. Köhler, and C. Milstein Continuous cultures of fused cells secreting antibody of predefined specificity Nature 256 1975 495 497
2. M.F. Fajt, and S.E. Wenzel Asthma phenotypes and the use of biologic medications in asthma and allergic disease: the next steps toward personalized care J Allergy Clin Immunol 135 2015 299 310
3. R.N. Bauer, M. Manohar, A.M. Singh, D.C. Jay, and K.C. Nadeau The future of biologics: applications for food allergy J Allergy Clin Immunol 135 2015 312 323
4. J.A. Boyce, A. Assa'ad, A.W. Burks, S.M. Jones, H.A. Sampson, and R.A. Wood Guidelines for the diagnosis and management of food allergy in the United States: report of the NIAID-sponsored expert panel J Allergy Clin Immunol 126 suppl 2010 S1 S58
5. H.A. Sampson, S. Aceves, S.A. Bock, J. James, S. Jones, and D. Lang Food allergy: a practice parameter update - 2014 J Allergy Clin Immunol 134 2014 1016 1025
6. H.A. Sampson Peanut oral immunotherapy: is it ready for clinical practice? J Allergy Clin Immunol Pract 1 2013 15 21
7. R.A. Wood, and H.A. Sampson Oral immunotherapy for the treatment of peanut allergy: is it ready for prime time? J Allergy Clin Immunol Pract 2 2014 97 98
8. B.P. Vickery, A.M. Scurlock, M. Kulis, P.H. Steele, J. Kamilaris, and J.P. Berglund Sustained unresponsiveness to peanut in subjects who have completed peanut oral immunotherapy J Allergy Clin Immunol 133 2014 468 475
9. S. Noda, J.G. Krueger, and E. Guttman-Yassky The translational revolution and use of biologics in patients with inflammatory skin diseases J Allergy Clin Immunol 135 2015 324 336
10. L.A. Beck, D. Thaçi, J.D. Hamilton, N.M. Graham, T. Bieber, and R. Rocklin Dupilumab treatment in adults with moderate-to-severe atopic dermatitis N Engl J Med 371 2014 130 139
11. J.D. Hamilton, M. Suárez-Fariñas, N. Dhingra, I. Cardinale, X. Li, and A. Kostic Dupilumab improves the molecular signature in skin of patients with moderate-to-severe atopic dermatitis J Allergy Clin Immunol 134 2014 1293 1300
12. M. Suárez-Fariñas, J.K. Gittler, A. Shemer, I. Cardinale, J.G. Krueger, and E. Guttman-Yassky Residual genomic signature of atopic dermatitis despite clinical resolution with narrow-band UVB J Allergy Clin Immunol 131 2013 577 579
13. M. Laviolette, D.L. Gossage, G. Gauvreau, R. Leigh, R. Olivenstein, and R. Katial Effects of benralizumab on airway eosinophils in asthmatic patients with sputum eosinophilia J Allergy Clin Immunol 133 2014 1232
14. E.H. De Boever, C. Ashman, A.P. Cahn, N.W. Locantore, P. Overend, and I.J. Pouliquen Efficacy and safety of an anti-IL-13 mAb in patients with severe asthma: a randomized trial J Allergy Clin Immunol 133 2014 989 996
15. P. Haldar, C.E. Brightling, A. Singapuri, B. Hargadon, S. Gupta, and W. Monteiro Outcomes after cessation of mepolizumab therapy in severe eisinophilic asthma: a 12-month follow-up analysis J Allergy Clin Immunol 133 2014 921 923
16. D.T. Cheng, C. Ma, J. Niewoehner, M. Dahl, A. Tsai, and J. Zhang Thymic stromal lymphopoietin receptor blockade reduces allergic inflammation in a cynomolgus monkey model of asthma J Allergy Clin Immunol 132 2013 455 462
17. W. Busse, S. Spector, K. Rosén, Y. Wang, and O. Alpan High eosinophil count: a potential biomarker for assessing successful omalizumab treatment effects J Allergy Clin Immunol 132 2013 485 486
18. A. Long, A. Rahmaoui, K.J. Rothman, E. Guinan, M. Eisner, and M.S. Bradley Incidence of malignancy in patients with moderate-to-severe asthma treat with or without omalizumab J Allergy Clin Immunol 134 2014 560 567
19. P. Gevaert, L. Calus, T. Van Zele, K. Blomme, N. De Ruyck, and W. Bauters Omalizumab is effective in allergic and nonallergic patients with nasal polyps and asthma J Allergy Clin Immunol 131 2013 110 116
20. A. Kaplan, D. Ledford, M. Ashby, J. Canvin, J.L. Zazzali, and E. Conner Omalizumab in patients with symptomatic chronic idiopathic/spontaneous urticaria despite standard combination therapy J Allergy Clin Immunol 132 2013 101 109
21. L.C. Schneider, R. Rachid, J. LeBovidge, E. Blood, M. Mittal, and D.T. Umetsu A pilot study of omalizumab to facilitate rapid oral desensitization in high-risk peanut-allergic patients J Allergy Clin Immunol 132 2013 1368 1374
22. F.E. Roufosse, J.E. Kahn, G.J. Gleich, L.B. Schwartz, A.D. Singh, and L.J. Rosenwasser Long-term safety of mepolizumab for the treatment of hypereosinophilic syndromes J Allergy Clin Immunol 131 2013 461 467
23. I.M. Otani, A.A. Anilkumar, R.O. Newbury, M. Bhagat, L.Y. Beppu, and R. Dohil Anti-Il-5 therapy reduces mast cell and IL-9 cell numbers in pediatric patients with eosinophilic esophagitis J Allergy Clin Immunol 131 2013 1576 1582