Transplantation of cerebellar neural stem cells improves motor coordination and neuropathology in Machado-Joseph disease mice

Brain

Volumn 138, Issue 2, 2015, Pages 320-335

  Mendonça, Liliana S ^a   Nóbrega, Clévio ^a   Hirai, Hirokazu ^b   Kaspar, Brian K ^c   De Almeida, Lu'̈ Pereira ^a,d  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b GUNMA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^d UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

Cerebellar neural stem cells transplantation; Neuroinflammation; Neuropathology and motor coordination; Neurotrophic factors; Spinocerebellar ataxia type 3

Indexed keywords

ATAXIN 3; NEUROTRANSMITTER RECEPTOR; NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN NERVE CELL; CELL SURVIVAL; CEREBELLUM; CONTROLLED STUDY; LOCOMOTION; MACHADO JOSEPH DISEASE; MEDIATOR RELEASE; MOTOR COORDINATION; MOTOR DYSFUNCTION; MOUSE; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM INFLAMMATION; NEURAL STEM CELL TRANSPLANTATION; NEUROPATHOLOGY; NEUROPROTECTION; NONHUMAN; OLIGODENDROGLIA; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PURKINJE CELL; TRANSGENIC MOUSE; ANIMAL; ATAXIA; C57BL MOUSE; CELL CULTURE; CELL DIFFERENTIATION; CELL SEPARATION; CYTOLOGY; MACHADO-JOSEPH DISEASE; METABOLISM; NEURAL STEM CELL; NEURITIS; PATHOLOGY; PSYCHOMOTOR PERFORMANCE; TRANSPLANTATION;

ANIMALS; ATAXIA; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL DIFFERENTIATION; CELL SEPARATION; CELLS, CULTURED; CEREBELLUM; MACHADO-JOSEPH DISEASE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEURAL STEM CELLS; NEURITIS; PSYCHOMOTOR PERFORMANCE; RECEPTORS, NEUROTRANSMITTER;

EID: 84922366384     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awu352     Document Type: Article

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