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Volumn 33, Issue 7, 2013, Pages 1013-1022

Neural stem cells grafts decrease neural apoptosis associated with caspase-7 downregulation and BDNF upregulation in rats following spinal cord hemisection

Author keywords

BDNF; Caspase 7; Hemisected spinal cord injury; Neuroprotection; NSCs transplantation

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; CASPASE 3; CASPASE 7; MESSENGER RNA;

EID: 84885178352     PISSN: 02724340     EISSN: 15736830     Source Type: Journal    
DOI: 10.1007/s10571-013-9969-9     Document Type: Article
Times cited : (8)

References (41)
  • 1
    • 0028919411 scopus 로고
    • A sensitive and reliable locomotor rating scale for open field testing in rats
    • 7783230 10.1089/neu.1995.12.1 1:STN:280:DyaK2Mzgt1GhtQ%3D%3D
    • Basso DM, Beattie MS, Bresnahan JC (1995) A sensitive and reliable locomotor rating scale for open field testing in rats. J Neurotrauma 12:1-21
    • (1995) J Neurotrauma , vol.12 , pp. 1-21
    • Basso, D.M.1    Beattie, M.S.2    Bresnahan, J.C.3
  • 2
    • 0036098072 scopus 로고    scopus 로고
    • Neurotrophic factors, gene therapy, and neural stem cells for spinal cord repair
    • 12031281 10.1016/S0361-9230(01)00774-2 1:CAS:528:DC%2BD38XjvVGitr4%3D
    • Blesch A, Lu P, Tuszynski MH (2002) Neurotrophic factors, gene therapy, and neural stem cells for spinal cord repair. Brain Res Bull 57:833-838
    • (2002) Brain Res Bull , vol.57 , pp. 833-838
    • Blesch, A.1    Lu, P.2    Tuszynski, M.H.3
  • 3
    • 55049102601 scopus 로고    scopus 로고
    • Viability-dependent promoting action of adult neural precursors in spinal cord injury
    • 18654659 10.2119/2008-00077.Bottai 1:CAS:528:DC%2BD1cXht1ems7zN
    • Bottai D, Madaschi L, Di Giulio AM, Gorio A (2008) Viability-dependent promoting action of adult neural precursors in spinal cord injury. Mol Med 14:634-644
    • (2008) Mol Med , vol.14 , pp. 634-644
    • Bottai, D.1    Madaschi, L.2    Di Giulio, A.M.3    Gorio, A.4
  • 4
    • 79951471028 scopus 로고    scopus 로고
    • Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells and Schwann cells
    • 1:CAS:528:DC%2BC3cXht1OlsrnP
    • Chen G, Hu YR, Wan H, Xia L, Li JH, Yang F, Qu X, Wang SG, Wang ZC (2010) Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells and Schwann cells. Chin Med J (Engl) 123:2424-2431
    • (2010) Chin Med J (Engl) , vol.123 , pp. 2424-2431
    • Chen, G.1    Hu, Y.R.2    Wan, H.3    Xia, L.4    Li, J.H.5    Yang, F.6    Qu, X.7    Wang, S.G.8    Wang, Z.C.9
  • 5
    • 0037362044 scopus 로고    scopus 로고
    • Migration and differentiation of neural progenitor cells from two different regions of embryonic central nervous system after transplantation into the intact spinal cord
    • 12670310 10.1046/j.1460-9568.2003.02555.x
    • Enomoto M, Shinomiya K, Okabe S (2003) Migration and differentiation of neural progenitor cells from two different regions of embryonic central nervous system after transplantation into the intact spinal cord. Eur J Neurosci 17:1223-1232
    • (2003) Eur J Neurosci , vol.17 , pp. 1223-1232
    • Enomoto, M.1    Shinomiya, K.2    Okabe, S.3
  • 6
    • 49049085216 scopus 로고    scopus 로고
    • Neural stem cell delivery to the spinal cord in an ovine model of fetal surgery for spina bifida
    • 18707035 10.1016/j.surg.2008.05.009
    • Fauza DO, Jennings RW, Teng YD, Snyder EY (2008) Neural stem cell delivery to the spinal cord in an ovine model of fetal surgery for spina bifida. Surgery 144:367-373
    • (2008) Surgery , vol.144 , pp. 367-373
    • Fauza, D.O.1    Jennings, R.W.2    Teng, Y.D.3    Snyder, E.Y.4
  • 7
    • 73949115635 scopus 로고    scopus 로고
    • Stem cells in the adult rat spinal cord: Plasticity after injury and treadmill training exercise
    • 19925583 10.1111/j.1471-4159.2009.06500.x 1:CAS:528:DC%2BC3cXht1erur0%3D
    • Foret A, Quertainmont R, Botman O, Bouhy D, Amabili P, Brook G, Schoenen J, Franzen R (2010) Stem cells in the adult rat spinal cord: plasticity after injury and treadmill training exercise. J Neurochem 112:762-772
    • (2010) J Neurochem , vol.112 , pp. 762-772
    • Foret, A.1    Quertainmont, R.2    Botman, O.3    Bouhy, D.4    Amabili, P.5    Brook, G.6    Schoenen, J.7    Franzen, R.8
  • 8
    • 84867571197 scopus 로고    scopus 로고
    • Neurotrophin expressions in neural stem cells grafted acutely to transected spinal cord of adult rats linked to functional improvement
    • 22573254 10.1007/s10571-012-9832-4 1:CAS:528:DC%2BC38XhsVCjurzK
    • Gu YL, Yin LW, Zhang Z, Liu J, Liu SJ, Zhang LF, Wang TH (2012) Neurotrophin expressions in neural stem cells grafted acutely to transected spinal cord of adult rats linked to functional improvement. Cell Mol Neurobiol 32:1089-1097
    • (2012) Cell Mol Neurobiol , vol.32 , pp. 1089-1097
    • Gu, Y.L.1    Yin, L.W.2    Zhang, Z.3    Liu, J.4    Liu, S.J.5    Zhang, L.F.6    Wang, T.H.7
  • 9
    • 71549158807 scopus 로고    scopus 로고
    • Ferulic acid induces neural progenitor cell proliferation in vitro and in vivo
    • 19837139 10.1016/j.neuroscience.2009.10.023
    • Harada N, Ito N, Nagai T, Sanagi T, Yamada H (2010) Ferulic acid induces neural progenitor cell proliferation in vitro and in vivo. Neuroscience 165:515-524
    • (2010) Neuroscience , vol.165 , pp. 515-524
    • Harada, N.1    Ito, N.2    Nagai, T.3    Sanagi, T.4    Yamada, H.5
  • 10
    • 18144431373 scopus 로고    scopus 로고
    • Embryonic radial glia bridge spinal cord lesions and promote functional recovery following spinal cord injury
    • 15869942 10.1016/j.expneurol.2004.12.024 1:CAS:528:DC%2BD2MXjslKjuro%3D
    • Hasegawa K, Chang YW, Li H, Berlin Y, Ikeda O, Kane-Goldsmith N, Grumet M (2005) Embryonic radial glia bridge spinal cord lesions and promote functional recovery following spinal cord injury. Exp Neurol 193:394-410
    • (2005) Exp Neurol , vol.193 , pp. 394-410
    • Hasegawa, K.1    Chang, Y.W.2    Li, H.3    Berlin, Y.4    Ikeda, O.5    Kane-Goldsmith, N.6    Grumet, M.7
  • 11
    • 84873060126 scopus 로고    scopus 로고
    • BDNF expression with functional improvement in transected spinal cord treated with neural stem cells in adult rats
    • 22959240 10.1016/j.npep.2012.06.001 1:CAS:528:DC%2BC38XhtlSgu7fI
    • He BL, Ba YC, Wang XY, Liu SJ, Liu GD, Ou S, Gu YL, Pan XH, Wang TH (2013) BDNF expression with functional improvement in transected spinal cord treated with neural stem cells in adult rats. Neuropeptides 47(1):1-7
    • (2013) Neuropeptides , vol.47 , Issue.1 , pp. 1-7
    • He, B.L.1    Ba, Y.C.2    Wang, X.Y.3    Liu, S.J.4    Liu, G.D.5    Ou, S.6    Gu, Y.L.7    Pan, X.H.8    Wang, T.H.9
  • 12
    • 33747157935 scopus 로고    scopus 로고
    • Fate of endogenous stem/progenitor cells following spinal cord injury
    • 16874803 10.1002/cne.21065
    • Horky LL, Galimi F, Gage FH, Horner PJ (2006) Fate of endogenous stem/progenitor cells following spinal cord injury. J Comp Neurol 498:525-538
    • (2006) J Comp Neurol , vol.498 , pp. 525-538
    • Horky, L.L.1    Galimi, F.2    Gage, F.H.3    Horner, P.J.4
  • 13
    • 70349785405 scopus 로고    scopus 로고
    • Transplantation of human neural stem cells transduced with Olig2 transcription factor improves locomotor recovery and enhances myelination in the white matter of rat spinal cord following contusive injury
    • 19772605 10.1186/1471-2202-10-117
    • Hwang DH, Kim BG, Kim EJ, Lee SI, Joo IS, Suh-Kim H, Sohn S, Kim SU (2009) Transplantation of human neural stem cells transduced with Olig2 transcription factor improves locomotor recovery and enhances myelination in the white matter of rat spinal cord following contusive injury. BMC Neurosci 10:117
    • (2009) BMC Neurosci , vol.10 , pp. 117
    • Hwang, D.H.1    Kim, B.G.2    Kim, E.J.3    Lee, S.I.4    Joo, I.S.5    Suh-Kim, H.6    Sohn, S.7    Kim, S.U.8
  • 14
    • 0030448423 scopus 로고    scopus 로고
    • Single factors direct the differentiation of stem cells from the fetal and adult central nervous system
    • 8985182 10.1101/gad.10.24.3129 1:CAS:528:DyaK2sXjsV2guw%3D%3D
    • Johe KK, Hazel TG, Muller T, Dugich-Djordjevic MM, McKay RD (1996) Single factors direct the differentiation of stem cells from the fetal and adult central nervous system. Genes Dev 10:3129-3140
    • (1996) Genes Dev , vol.10 , pp. 3129-3140
    • Johe, K.K.1    Hazel, T.G.2    Muller, T.3    Dugich-Djordjevic, M.M.4    McKay, R.D.5
  • 15
    • 84868158857 scopus 로고    scopus 로고
    • Reactive astrogliosis after spinal cord injury-beneficial and detrimental effects
    • 22684804 10.1007/s12035-012-8287-4 1:CAS:528:DC%2BC38XhsVeiurfO
    • Karimi-Abdolrezaee S, Billakanti R (2012) Reactive astrogliosis after spinal cord injury-beneficial and detrimental effects. Mol Neurobiol 46:251-264
    • (2012) Mol Neurobiol , vol.46 , pp. 251-264
    • Karimi-Abdolrezaee, S.1    Billakanti, R.2
  • 16
    • 63449139550 scopus 로고    scopus 로고
    • Ex vivo VEGF delivery by neural stem cells enhances proliferation of glial progenitors, angiogenesis, and tissue sparing after spinal cord injury
    • 19319198 10.1371/journal.pone.0004987
    • Kim HM, Hwang DH, Lee JE, Kim SU, Kim BG (2009) Ex vivo VEGF delivery by neural stem cells enhances proliferation of glial progenitors, angiogenesis, and tissue sparing after spinal cord injury. PLoS One 4:e4987
    • (2009) PLoS One , vol.4 , pp. 4987
    • Kim, H.M.1    Hwang, D.H.2    Lee, J.E.3    Kim, S.U.4    Kim, B.G.5
  • 18
    • 84885094003 scopus 로고    scopus 로고
    • Electro-acupuncture treatment improves neurological function associated with downregulation of PDGF and inhibition of astrogliosis in rats with spinal cord transaction
    • Pubmed ahead
    • Liu F, Zou Y, Liu SJ, Liu J, Wang TH (2013). Electro-acupuncture treatment improves neurological function associated with downregulation of PDGF and inhibition of astrogliosis in rats with spinal cord transaction. J Mol Neurosci. Pubmed ahead
    • (2013) J Mol Neurosci
    • Liu, F.1    Zou, Y.2    Liu, S.J.3    Liu, J.4    Wang, T.H.5
  • 19
    • 0038054469 scopus 로고    scopus 로고
    • Neural stem cells constitutively secrete neurotrophic factors and promote extensive host axonal growth after spinal cord injury
    • 12781986 10.1016/S0014-4886(03)00037-2 1:CAS:528:DC%2BD3sXktFGiur8%3D
    • Lu P, Jones LL, Snyder EY, Tuszynski MH (2003) Neural stem cells constitutively secrete neurotrophic factors and promote extensive host axonal growth after spinal cord injury. Exp Neurol 181:115-129
    • (2003) Exp Neurol , vol.181 , pp. 115-129
    • Lu, P.1    Jones, L.L.2    Snyder, E.Y.3    Tuszynski, M.H.4
  • 20
    • 33748426473 scopus 로고    scopus 로고
    • Pain with no gain: Allodynia following neural stem cell transplantation in spinal cord injury
    • 16839548 10.1016/j.expneurol.2006.04.035 1:CAS:528:DC%2BD28XpslSmtbY%3D
    • Macias MY, Syring MB, Pizzi MA, Crowe MJ, Alexanian AR, Kurpad SN (2006) Pain with no gain: allodynia following neural stem cell transplantation in spinal cord injury. Exp Neurol 201:335-348
    • (2006) Exp Neurol , vol.201 , pp. 335-348
    • Macias, M.Y.1    Syring, M.B.2    Pizzi, M.A.3    Crowe, M.J.4    Alexanian, A.R.5    Kurpad, S.N.6
  • 21
    • 33846241316 scopus 로고    scopus 로고
    • Transplantation of bioreactor-produced neural stem cells into the rodent brain
    • 17269440 10.3727/000000006783464426 1:STN:280:DC%2BD2s%2Fms1KitA%3D%3D
    • McLeod M, Hong M, Sen A, Sadi D, Ulalia R, Behie LA, Mendez I (2006) Transplantation of bioreactor-produced neural stem cells into the rodent brain. Cell Transplant 15:689-697
    • (2006) Cell Transplant , vol.15 , pp. 689-697
    • McLeod, M.1    Hong, M.2    Sen, A.3    Sadi, D.4    Ulalia, R.5    Behie, L.A.6    Mendez, I.7
  • 22
    • 77954906493 scopus 로고    scopus 로고
    • Distribution, differentiation, and survival of intravenously administered neural stem cells in a rat model of amyotrophic lateral sclerosis
    • 20350352 10.3727/096368910X498269
    • Mitrecić D, Nicaise C, Gajović S, Pochet R (2010) Distribution, differentiation, and survival of intravenously administered neural stem cells in a rat model of amyotrophic lateral sclerosis. Cell Transplant 19:537-548
    • (2010) Cell Transplant , vol.19 , pp. 537-548
    • Mitrecić, D.1    Nicaise, C.2    Gajović, S.3    Pochet, R.4
  • 24
    • 31544440415 scopus 로고    scopus 로고
    • Transplantation of neural stem cells for spinal cord injury
    • 16447750
    • Nakamura M, Toyama Y, Okano H (2005) Transplantation of neural stem cells for spinal cord injury. Rinsho Shinkeigaku 45:874-876
    • (2005) Rinsho Shinkeigaku , vol.45 , pp. 874-876
    • Nakamura, M.1    Toyama, Y.2    Okano, H.3
  • 25
    • 78651081165 scopus 로고    scopus 로고
    • Brain and spinal cord affected by amyotrophic lateral sclerosis induce differential growth factors expression in rat mesenchymal and neural stem cells
    • 20846186 10.1111/j.1365-2990.2010.01124.x 1:CAS:528:DC%2BC3MXhvVGmurk%3D
    • Nicaise C, Mitrecic D, Pochet R (2011) Brain and spinal cord affected by amyotrophic lateral sclerosis induce differential growth factors expression in rat mesenchymal and neural stem cells. Neuropathol Appl Neurobiol 37:179-188
    • (2011) Neuropathol Appl Neurobiol , vol.37 , pp. 179-188
    • Nicaise, C.1    Mitrecic, D.2    Pochet, R.3
  • 26
    • 79959509244 scopus 로고    scopus 로고
    • Neuroprotective signaling mechanisms of telomerase are regulated by brain-derived neurotrophic factor in rat spinal cord motor neurons
    • 21666495 10.1097/NEN.0b013e318222b97b 1:CAS:528:DC%2BC3MXnslensLs%3D
    • Niu C, Yip HK (2011) Neuroprotective signaling mechanisms of telomerase are regulated by brain-derived neurotrophic factor in rat spinal cord motor neurons. J Neuropathol Exp Neurol 70:634-652
    • (2011) J Neuropathol Exp Neurol , vol.70 , pp. 634-652
    • Niu, C.1    Yip, H.K.2
  • 27
    • 67650682083 scopus 로고    scopus 로고
    • Neural stem cell and Schwann cell-loaded biodegradable polymer scaffolds support axonal regeneration in the transected spinal cord
    • 19191513 10.1089/ten.tea.2008.0364 1:CAS:528:DC%2BD1MXos1Wjsro%3D
    • Olson HE, Rooney GE, Gross L, Nesbitt JJ, Galvin KE, Knight A, Chen B, Yaszemski MJ, Windebank AJ (2009) Neural stem cell and Schwann cell-loaded biodegradable polymer scaffolds support axonal regeneration in the transected spinal cord. Tissue Eng Part A 15:1797-1805
    • (2009) Tissue Eng Part A , vol.15 , pp. 1797-1805
    • Olson, H.E.1    Rooney, G.E.2    Gross, L.3    Nesbitt, J.J.4    Galvin, K.E.5    Knight, A.6    Chen, B.7    Yaszemski, M.J.8    Windebank, A.J.9
  • 28
    • 84871408179 scopus 로고    scopus 로고
    • Neurotrophin regulation of neural circuit development and function
    • 10.1038/nrn3379
    • Park H, Poo MM (2012) Neurotrophin regulation of neural circuit development and function. Nat Rev Neurosci 14:7-23
    • (2012) Nat Rev Neurosci , vol.14 , pp. 7-23
    • Park, H.1    Poo, M.M.2
  • 29
    • 12244297111 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and death in motor neurons exposed to the glutathione-depleting agent ethacrynic acid
    • 12614931 10.1016/S0022-510X(02)00357-X 1:CAS:528:DC%2BD3sXhsVClur0%3D
    • Rizzardini M, Lupi M, Bernasconi S, Mangolini A, Cantoni L (2003) Mitochondrial dysfunction and death in motor neurons exposed to the glutathione-depleting agent ethacrynic acid. J Neurol Sci 207:51-58
    • (2003) J Neurol Sci , vol.207 , pp. 51-58
    • Rizzardini, M.1    Lupi, M.2    Bernasconi, S.3    Mangolini, A.4    Cantoni, L.5
  • 30
    • 84866174647 scopus 로고    scopus 로고
    • Stress-resistant neural stem cells positively influence regional energy metabolism after spinal cord injury in mice
    • 21833653 10.1007/s12031-011-9600-9 1:CAS:528:DC%2BC38Xhsl2nsbo%3D
    • Schwerdtfeger K, Mautes AE, Bernreuther C, Cui Y, Manville J, Dihné M, Blank S, Schachner M (2012) Stress-resistant neural stem cells positively influence regional energy metabolism after spinal cord injury in mice. J Mol Neurosci 46:401-409
    • (2012) J Mol Neurosci , vol.46 , pp. 401-409
    • Schwerdtfeger, K.1    Mautes, A.E.2    Bernreuther, C.3    Cui, Y.4    Manville, J.5    Dihné, M.6    Blank, S.7    Schachner, M.8
  • 31
    • 4644244652 scopus 로고    scopus 로고
    • Nuclear export of OLIG2 in neural stem cells is essential for ciliary neurotrophic factor-induced astrocyte differentiation
    • 15452140 10.1083/jcb.200404104 1:CAS:528:DC%2BD2cXotVeht7c%3D
    • Setoguchi T, Kondo T (2004) Nuclear export of OLIG2 in neural stem cells is essential for ciliary neurotrophic factor-induced astrocyte differentiation. J Cell Biol 166:963-968
    • (2004) J Cell Biol , vol.166 , pp. 963-968
    • Setoguchi, T.1    Kondo, T.2
  • 32
    • 66849122038 scopus 로고    scopus 로고
    • Experimental study on neural stem cell transplantation delaying denervated muscle atrophy
    • 18822726
    • Shen Y, Xu J, Xu W, Xu L, Lu J, Gu Y (2008) Experimental study on neural stem cell transplantation delaying denervated muscle atrophy. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 22(9):1051-1055
    • (2008) Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi , vol.22 , Issue.9 , pp. 1051-1055
    • Shen, Y.1    Xu, J.2    Xu, W.3    Xu, L.4    Lu, J.5    Gu, Y.6
  • 33
    • 34648823374 scopus 로고    scopus 로고
    • Intravenously transplanted human neural stem cells migrate to the injured spinal cord in adult mice in an SDF-1- and HGF-dependent manner
    • 17884290 10.1016/j.neulet.2007.08.048 1:CAS:528:DC%2BD2sXhtFWiurjN
    • Takeuchi H, Natsume A, Wakabayashi T, Aoshima C, Shimato S, Ito M, Ishii J, Maeda Y, Hara M, Kim SU, Yoshida J (2007) Intravenously transplanted human neural stem cells migrate to the injured spinal cord in adult mice in an SDF-1- and HGF-dependent manner. Neurosci Lett 426(2):69-74
    • (2007) Neurosci Lett , vol.426 , Issue.2 , pp. 69-74
    • Takeuchi, H.1    Natsume, A.2    Wakabayashi, T.3    Aoshima, C.4    Shimato, S.5    Ito, M.6    Ishii, J.7    Maeda, Y.8    Hara, M.9    Kim, S.U.10    Yoshida, J.11
  • 35
    • 77954189278 scopus 로고    scopus 로고
    • Direct intrathecal implantation of mesenchymal stromal cells leads to enhanced neuroprotection via an NF kappaB-mediated increase in interleukin-6 production
    • 19775197 10.1089/scd.2009.0188 1:CAS:528:DC%2BC3cXnvFSjsLo%3D
    • Walker PA, Harting MT, Jimenez F, Shah SK, Pati S, Dash PK, Cox CS Jr (2010) Direct intrathecal implantation of mesenchymal stromal cells leads to enhanced neuroprotection via an NF kappaB-mediated increase in interleukin-6 production. Stem Cells Dev 19:867-876
    • (2010) Stem Cells Dev , vol.19 , pp. 867-876
    • Walker, P.A.1    Harting, M.T.2    Jimenez, F.3    Shah, S.K.4    Pati, S.5    Dash, P.K.6    Cox, Jr.C.S.7
  • 36
    • 78650512417 scopus 로고    scopus 로고
    • Administration of BDNF/ginsenosides combination enhanced synaptic development in human neural stem cells
    • 21094185 10.1016/j.jneumeth.2010.10.025 1:CAS:528:DC%2BC3cXhs1Wkur3F
    • Wang L, Kisaalita WS (2011) Administration of BDNF/ginsenosides combination enhanced synaptic development in human neural stem cells. J Neurosci Methods 194:274-282
    • (2011) J Neurosci Methods , vol.194 , pp. 274-282
    • Wang, L.1    Kisaalita, W.S.2
  • 37
    • 84886637078 scopus 로고    scopus 로고
    • Expression of PDGF, EGF and GDNF in cultured NSCs of mice in vitro
    • Wang B, Dan QQ, Li Y (2010). Expression of PDGF, EGF and GDNF in cultured NSCs of mice in vitro. J Kunming Medical University 11:13-16
    • (2010) J Kunming Medical University , vol.11 , pp. 13-16
    • Wang, B.1    Dan, Q.Q.2    Li, Y.3
  • 38
    • 80051544206 scopus 로고    scopus 로고
    • Cograft of neural stem cells and schwann cells overexpressing TrkC and neurotrophin-3 respectively after rat spinal cord transection
    • 21783247 10.1016/j.biomaterials.2011.06.036 1:CAS:528:DC%2BC3MXhtVSqtrbO
    • Wang JM, Zeng YS, Wu JL, Li Y, Teng YD (2011) Cograft of neural stem cells and schwann cells overexpressing TrkC and neurotrophin-3 respectively after rat spinal cord transection. Biomaterials 32:7454-7468
    • (2011) Biomaterials , vol.32 , pp. 7454-7468
    • Wang, J.M.1    Zeng, Y.S.2    Wu, J.L.3    Li, Y.4    Teng, Y.D.5
  • 39
    • 65649090629 scopus 로고    scopus 로고
    • Human neural stem cell grafts in the spinal cord of SOD1 transgenic rats: Differentiation and structural integration into the segmental motor circuitry
    • 19326469 10.1002/cne.22022 1:CAS:528:DC%2BD1MXlsFOntbY%3D
    • Xu L, Ryugo DK, Pongstaporn T, Johe K, Koliatsos VE (2009) Human neural stem cell grafts in the spinal cord of SOD1 transgenic rats: differentiation and structural integration into the segmental motor circuitry. J Comp Neurol 514:297-309
    • (2009) J Comp Neurol , vol.514 , pp. 297-309
    • Xu, L.1    Ryugo, D.K.2    Pongstaporn, T.3    Johe, K.4    Koliatsos, V.E.5
  • 40
    • 7544234209 scopus 로고    scopus 로고
    • Differentiation and tropic/trophic effects of exogenous neural precursors in the adult spinal cord
    • 15514921 10.1002/cne.20344
    • Yan J, Welsh AM, Bora SH, Snyder EY, Koliatsos VE (2004) Differentiation and tropic/trophic effects of exogenous neural precursors in the adult spinal cord. J Comp Neurol 480:101-114
    • (2004) J Comp Neurol , vol.480 , pp. 101-114
    • Yan, J.1    Welsh, A.M.2    Bora, S.H.3    Snyder, E.Y.4    Koliatsos, V.E.5
  • 41
    • 78049482415 scopus 로고    scopus 로고
    • Functional and histological improvement of the injured spinal cord following transplantation of Schwann cells transfected with NRG1 gene
    • 10.1002/ar.21223
    • Zhang J, Zhao F, Wu G, Li Y, Jin X (2010) Functional and histological improvement of the injured spinal cord following transplantation of Schwann cells transfected with NRG1 gene. Anat Rec (Hoboken) 293:1933-1946
    • (2010) Anat Rec (Hoboken) , vol.293 , pp. 1933-1946
    • Zhang, J.1    Zhao, F.2    Wu, G.3    Li, Y.4    Jin, X.5


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