메뉴 건너뛰기




Volumn 35, Issue 12, 2014, Pages 1043-1048

Trans-placental passage and anti-inflammatory effects of solithromycin in the human placenta

Author keywords

Inflammation; Intrauterine infection; Macrolide; Perfusion; Placenta

Indexed keywords

CREATININE; INTERLEUKIN 6; SOLITHROMYCIN; TUMOR NECROSIS FACTOR ALPHA; ANTIINFECTIVE AGENT; MACROLIDE; TRIAZOLE DERIVATIVE;

EID: 84922325634     PISSN: 01434004     EISSN: 15323102     Source Type: Journal    
DOI: 10.1016/j.placenta.2014.09.009     Document Type: Article
Times cited : (12)

References (51)
  • 5
    • 84862562387 scopus 로고    scopus 로고
    • The outcomes of pregnancy in women exposed to the new macrolides in the first trimester: A prospective, multicentre, observational study
    • Bar-Oz B, Weber-Schoendorfer C, Berlin M, Clementi M, Di Gianantonio E, de Vries L, et al. The outcomes of pregnancy in women exposed to the new macrolides in the first trimester: a prospective, multicentre, observational study. Drug Saf 2012;35(7):589-98.
    • (2012) Drug Saf , vol.35 , Issue.7 , pp. 589-598
    • Bar-Oz, B.1    Weber-Schoendorfer, C.2    Berlin, M.3    Clementi, M.4    Di Gianantonio, E.5    De Vries, L.6
  • 6
    • 80053179622 scopus 로고    scopus 로고
    • Distribution characteristics of clarithromycin and azithromycin, macrolide antimicrobial agents used for treatment of respiratory infections, in lung epithelial lining fluid and alveolar macrophages
    • Togami K, Chono S, Morimoto K. Distribution characteristics of clarithromycin and azithromycin, macrolide antimicrobial agents used for treatment of respiratory infections, in lung epithelial lining fluid and alveolar macrophages. Biopharm Drug Dispos 2011;32(7):389-97.
    • (2011) Biopharm Drug Dispos , vol.32 , Issue.7 , pp. 389-397
    • Togami, K.1    Chono, S.2    Morimoto, K.3
  • 7
    • 0030933730 scopus 로고    scopus 로고
    • Requirements for intracellular accumulation and release of clarithromycin and azithromycin by human phagocytes
    • Fietta A, Merlini C, Gialdroni Grassi G. Requirements for intracellular accumulation and release of clarithromycin and azithromycin by human phagocytes. J Chemother 1997;9(1):23-31.
    • (1997) J Chemother , vol.9 , Issue.1 , pp. 23-31
    • Fietta, A.1    Merlini, C.2    Gialdroni Grassi, G.3
  • 8
    • 19544366269 scopus 로고    scopus 로고
    • Cellular uptake and efflux of azithromycin, erythromycin, clarithromycin, telithromycin, and cethromycin
    • Bosnar M, Kelneric Z, Munic V, Erakovic V, Parnham MJ. Cellular uptake and efflux of azithromycin, erythromycin, clarithromycin, telithromycin, and cethromycin. Antimicrob Agents Chemother 2005;49(6):2372-7.
    • (2005) Antimicrob Agents Chemother , vol.49 , Issue.6 , pp. 2372-2377
    • Bosnar, M.1    Kelneric, Z.2    Munic, V.3    Erakovic, V.4    Parnham, M.J.5
  • 11
    • 0034063430 scopus 로고    scopus 로고
    • The transplacental transfer of the macrolide antibiotics erythromycin, roxithromycin and azithromycin
    • Heikkinen T, Laine K, Neuvonen PJ, Ekblad U. The transplacental transfer of the macrolide antibiotics erythromycin, roxithromycin and azithromycin. Br J Obstet Gynaecol 2000;107(6):770-5.
    • (2000) Br J Obstet Gynaecol , vol.107 , Issue.6 , pp. 770-775
    • Heikkinen, T.1    Laine, K.2    Neuvonen, P.J.3    Ekblad, U.4
  • 12
    • 77954761478 scopus 로고    scopus 로고
    • Differences in assessment of macrolide interaction with human MDR1 (ABCB1, P-gp) using rhodamine-123 efflux, ATPase activity and cellular accumulation assays
    • Munic V, Kelneric Z, Mikac L, Erakovic Haber V. Differences in assessment of macrolide interaction with human MDR1 (ABCB1, P-gp) using rhodamine-123 efflux, ATPase activity and cellular accumulation assays. Eur J Pharm Sci 2010;41(1):86-95.
    • (2010) Eur J Pharm Sci , vol.41 , Issue.1 , pp. 86-95
    • Munic, V.1    Kelneric, Z.2    Mikac, L.3    Erakovic Haber, V.4
  • 13
    • 10744233896 scopus 로고    scopus 로고
    • Possible involvement of the drug transporters P glycoprotein and multidrug resistance-associated protein Mrp2 in disposition of azithromycin
    • Sugie M, Asakura E, Zhao YL, Torita S, Nadai M, Baba K, et al. Possible involvement of the drug transporters P glycoprotein and multidrug resistance-associated protein Mrp2 in disposition of azithromycin. Antimicrob Agents Chemother 2004;48(3):809-14.
    • (2004) Antimicrob Agents Chemother , vol.48 , Issue.3 , pp. 809-814
    • Sugie, M.1    Asakura, E.2    Zhao, Y.L.3    Torita, S.4    Nadai, M.5    Baba, K.6
  • 14
    • 84862321766 scopus 로고    scopus 로고
    • Transport characteristics of clarithromycin, azithromycin and telithromycin, antibiotics applied for treatment of respiratory infections, in Calu-3 cell monolayers as model lung epithelial cells
    • Togami K, Chono S, Morimoto K. Transport characteristics of clarithromycin, azithromycin and telithromycin, antibiotics applied for treatment of respiratory infections, in Calu-3 cell monolayers as model lung epithelial cells. Die Pharm 2012;67(5):389-93.
    • (2012) Die Pharm , vol.67 , Issue.5 , pp. 389-393
    • Togami, K.1    Chono, S.2    Morimoto, K.3
  • 15
    • 33846207538 scopus 로고    scopus 로고
    • Active transport across the human placenta: Impact on drug efficacy and toxicity
    • Evseenko D, Paxton JW, Keelan JA. Active transport across the human placenta: impact on drug efficacy and toxicity. Expert Opin Drug Metab Toxicol 2006;2(1):51-69.
    • (2006) Expert Opin Drug Metab Toxicol , vol.2 , Issue.1 , pp. 51-69
    • Evseenko, D.1    Paxton, J.W.2    Keelan, J.A.3
  • 16
    • 74049123564 scopus 로고    scopus 로고
    • The APPLe study: A randomized, community-based, placebo-controlled trial of azithromycin for the prevention of preterm birth, with meta-analysis
    • van den Broek NR, White SA, Goodall M, Ntonya C, Kayira E, Kafulafula G, et al. The APPLe study: a randomized, community-based, placebo-controlled trial of azithromycin for the prevention of preterm birth, with meta-analysis. PLoS Med 2009;6(12):e1000191.
    • (2009) PLoS Med , vol.6 , Issue.12 , pp. e1000191
    • Van Den-Broek, N.R.1    White, S.A.2    Goodall, M.3    Ntonya, C.4    Kayira, E.5    Kafulafula, G.6
  • 18
    • 84857401064 scopus 로고    scopus 로고
    • Antibiotics in the management of PROM and preterm labor
    • Mercer B. Antibiotics in the management of PROM and preterm labor. Obst Gynecol Clin North Am 2012;39(1):65-76.
    • (2012) Obst Gynecol Clin North Am , vol.39 , Issue.1 , pp. 65-76
    • Mercer, B.1
  • 19
    • 77957304930 scopus 로고    scopus 로고
    • In-vitro activities of tetracyclines, macrolides, fluoroquinolones and clindamycin against Mycoplasma hominis and Ureaplasma ssp. Isolated in Germany over 20 years
    • Krausse R, Schubert S. In-vitro activities of tetracyclines, macrolides, fluoroquinolones and clindamycin against Mycoplasma hominis and Ureaplasma ssp. isolated in Germany over 20 years. Clin Microbiol Infect 2010;16(11): 1649-55.
    • (2010) Clin Microbiol Infect , vol.16 , Issue.11 , pp. 1649-1655
    • Krausse, R.1    Schubert, S.2
  • 21
    • 84867330853 scopus 로고    scopus 로고
    • Improving known classes of antibiotics: An optimistic approach for the future
    • Bush K. Improving known classes of antibiotics: an optimistic approach for the future. Curr Opin Pharmacol 2012;12(5):527-34.
    • (2012) Curr Opin Pharmacol , vol.12 , Issue.5 , pp. 527-534
    • Bush, K.1
  • 22
    • 84901053866 scopus 로고    scopus 로고
    • In vitro activity of the new fluoroketolide solithromycin (CEM-101) against macrolide-resistant and -susceptible Mycoplasma genitalium strains
    • Jensen JS, Fernandes P, Unemo M. In vitro activity of the new fluoroketolide solithromycin (CEM-101) against macrolide-resistant and -susceptible Mycoplasma genitalium strains. Antimicrob Agents Chemother 2014;58(6): 3151-6.
    • (2014) Antimicrob Agents Chemother , vol.58 , Issue.6 , pp. 3151-3156
    • Jensen, J.S.1    Fernandes, P.2    Unemo, M.3
  • 23
    • 84860176932 scopus 로고    scopus 로고
    • In vitro activity of the new fluoroketolide solithromycin (CEM-101) against a large collection of clinical Neisseria gonorrhoeae isolates and international reference strains, including those with high-level antimicrobial resistance: Potential treatment option for gonorrhea?
    • Golparian D, Fernandes P, Ohnishi M, Jensen JS, Unemo M. In vitro activity of the new fluoroketolide solithromycin (CEM-101) against a large collection of clinical Neisseria gonorrhoeae isolates and international reference strains, including those with high-level antimicrobial resistance: potential treatment option for gonorrhea? Antimicrob Agents Chemother 2012;56(5):2739-42.
    • (2012) Antimicrob Agents Chemother , vol.56 , Issue.5 , pp. 2739-2742
    • Golparian, D.1    Fernandes, P.2    Ohnishi, M.3    Jensen, J.S.4    Unemo, M.5
  • 24
    • 78649634087 scopus 로고    scopus 로고
    • The in vitro evaluation of solithromycin (CEM-101) against pathogens isolated in the United States and Europe (2009)
    • Farrell DJ, Castanheira M, Sader HS, Jones RN. The in vitro evaluation of solithromycin (CEM-101) against pathogens isolated in the United States and Europe (2009). J Infect 2010;61(6):476-83.
    • (2010) J Infect , vol.61 , Issue.6 , pp. 476-483
    • Farrell, D.J.1    Castanheira, M.2    Sader, H.S.3    Jones, R.N.4
  • 25
    • 66149134798 scopus 로고    scopus 로고
    • Comparative in vitro susceptibilities of human mycoplasmas and ureaplasmas to a new investigational ketolide, CEM-101
    • Waites KB, Crabb DM, Duffy LB. Comparative in vitro susceptibilities of human mycoplasmas and ureaplasmas to a new investigational ketolide, CEM-101. Antimicrob Agents Chemother 2009;53(5):2139-41.
    • (2009) Antimicrob Agents Chemother , vol.53 , Issue.5 , pp. 2139-2141
    • Waites, K.B.1    Crabb, D.M.2    Duffy, L.B.3
  • 26
    • 84877846455 scopus 로고    scopus 로고
    • Randomized, double-blind, multicenter phase 2 study comparing the efficacy and safety of oral solithromycin (CEM-101) to those of oral levofloxacin in the treatment of patients with community-acquired bacterial pneumonia
    • Oldach D, Clark K, Schranz J, Das A, Craft JC, Scott D, et al. Randomized, double-blind, multicenter phase 2 study comparing the efficacy and safety of oral solithromycin (CEM-101) to those of oral levofloxacin in the treatment of patients with community-acquired bacterial pneumonia. Antimicrob Agents Chemother 2013;57(6):2526-34.
    • (2013) Antimicrob Agents Chemother , vol.57 , Issue.6 , pp. 2526-2534
    • Oldach, D.1    Clark, K.2    Schranz, J.3    Das, A.4    Craft, J.C.5    Scott, D.6
  • 27
    • 79955542813 scopus 로고    scopus 로고
    • Pharmacokinetics of solithromycin (CEM-101) after single or multiple oral doses and effects of food on single-dose bioavailability in healthy adult subjects
    • Still JG, Schranz J, Degenhardt TP, Scott D, Fernandes P, Gutierrez MJ, et al. Pharmacokinetics of solithromycin (CEM-101) after single or multiple oral doses and effects of food on single-dose bioavailability in healthy adult subjects. Antimicrob Agents Chemother 2011;55(5):1997-2003.
    • (2011) Antimicrob Agents Chemother , vol.55 , Issue.5 , pp. 1997-2003
    • Still, J.G.1    Schranz, J.2    Degenhardt, T.P.3    Scott, D.4    Fernandes, P.5    Gutierrez, M.J.6
  • 28
    • 84875413952 scopus 로고    scopus 로고
    • A novel macrolide solithromycin exerts superior anti-inflammatory effect via NFkappaB inhibition
    • Kobayashi Y, Wada H, Rossios C, Takagi D, Higaki M, Mikura S, et al. A novel macrolide solithromycin exerts superior anti-inflammatory effect via NFkappaB inhibition. J Pharmacol Exp Ther 2013;345(1):76-84.
    • (2013) J Pharmacol Exp Ther , vol.345 , Issue.1 , pp. 76-84
    • Kobayashi, Y.1    Wada, H.2    Rossios, C.3    Takagi, D.4    Higaki, M.5    Mikura, S.6
  • 29
    • 84891524394 scopus 로고    scopus 로고
    • Maternal administration of solithromycin, a new, potent, broad-spectrum fluoroketolide antibiotic, achieves fetal and intra-amniotic antimicrobial protection in a pregnant sheep model
    • Keelan JA, Kemp MW, Payne MS, Johnson D, Stock SJ, Saito M, et al. Maternal administration of solithromycin, a new, potent, broad-spectrum fluoroketolide antibiotic, achieves fetal and intra-amniotic antimicrobial protection in a pregnant sheep model. Antimicrob Agents Chemother 2014;58(1):447-54.
    • (2014) Antimicrob Agents Chemother , vol.58 , Issue.1 , pp. 447-454
    • Keelan, J.A.1    Kemp, M.W.2    Payne, M.S.3    Johnson, D.4    Stock, S.J.5    Saito, M.6
  • 30
    • 84922289871 scopus 로고    scopus 로고
    • Comparison of CEM-101 metabolism in mice, rats, monkeys and humans
    • Sept 12-15, Boston
    • Pereira DE, Degenhardt TP, Fernandes P. Comparison of CEM-101 metabolism in mice, rats, monkeys and humans. In: ICAAC Conference; 2010. Sept 12-15, Boston.
    • (2010) ICAAC Conference
    • Pereira, D.E.1    Degenhardt, T.P.2    Fernandes, P.3
  • 32
    • 84906095166 scopus 로고    scopus 로고
    • Maternal intravenous treatment with either azithromycin or solithromycin clears Ureaplasma parvum from the amniotic fluid in an ovine model of intrauterine infection
    • Miura Y, Payne MS, Keelan JA, Noe A, Carter S, Watts R, et al. Maternal intravenous treatment with either azithromycin or solithromycin clears Ureaplasma parvum from the amniotic fluid in an ovine model of intrauterine infection. Antimicrob Agents Chemother 2014;58(9):5413-20.
    • (2014) Antimicrob Agents Chemother , vol.58 , Issue.9 , pp. 5413-5420
    • Miura, Y.1    Payne, M.S.2    Keelan, J.A.3    Noe, A.4    Carter, S.5    Watts, R.6
  • 33
    • 34047190806 scopus 로고    scopus 로고
    • Animal models of human placentationea review
    • Carter AM. Animal models of human placentationea review. Placenta 2007;28(Suppl. A):S41-7.
    • (2007) Placenta , vol.28 , pp. S41-S47
    • Carter, A.M.1
  • 34
    • 35648954071 scopus 로고    scopus 로고
    • The human placentaean alternative for studying foetal exposure
    • Myren M, Mose T, Mathiesen L, Knudsen LE. The human placentaean alternative for studying foetal exposure. Toxicol In Vitro 2007;21(7):1332-40.
    • (2007) Toxicol in Vitro , vol.21 , Issue.7 , pp. 1332-1340
    • Myren, M.1    Mose, T.2    Mathiesen, L.3    Knudsen, L.E.4
  • 36
    • 79959377520 scopus 로고    scopus 로고
    • The human placental perfusion model: A systematic review and development of a model to predict in vivo transfer of therapeutic drugs
    • Hutson JR, Garcia-Bournissen F, Davis A, Koren G. The human placental perfusion model: a systematic review and development of a model to predict in vivo transfer of therapeutic drugs. Clin Pharmacol Ther 2011;90(1):67-76.
    • (2011) Clin Pharmacol Ther , vol.90 , Issue.1 , pp. 67-76
    • Hutson, J.R.1    Garcia-Bournissen, F.2    Davis, A.3    Koren, G.4
  • 38
    • 0021797203 scopus 로고
    • Maternal to fetal movement of creatinine as a measure of perfusion efficiency and diffusional transfer in the isolated human placental lobule
    • Eaton BM, Browne MJ, Contractor SF. Maternal to fetal movement of creatinine as a measure of perfusion efficiency and diffusional transfer in the isolated human placental lobule. Placenta 1985;6(4):341-6.
    • (1985) Placenta , vol.6 , Issue.4 , pp. 341-346
    • Eaton, B.M.1    Browne, M.J.2    Contractor, S.F.3
  • 39
    • 0015065550 scopus 로고
    • Creatinine assay in the presence of protein
    • Cook JG. Creatinine assay in the presence of protein. Clin Chim Acta 1971;32(3):485-6.
    • (1971) Clin Chim Acta , vol.32 , Issue.3 , pp. 485-486
    • Cook, J.G.1
  • 40
    • 84863753420 scopus 로고    scopus 로고
    • Oxysterols exert proinflammatory effects in placental trophoblasts via TLR4-dependent, cholesterol-sensitive activation of NF-kappaB
    • Aye IL, Waddell BJ, Mark PJ, Keelan JA. Oxysterols exert proinflammatory effects in placental trophoblasts via TLR4-dependent, cholesterol-sensitive activation of NF-kappaB. Mol Hum Reprod 2012;18(7):341-53.
    • (2012) Mol Hum Reprod , vol.18 , Issue.7 , pp. 341-353
    • Aye, I.L.1    Waddell, B.J.2    Mark, P.J.3    Keelan, J.A.4
  • 41
    • 77951776860 scopus 로고    scopus 로고
    • Innate inflammatory responses of human decidual cells to periodontopathic bacteria
    • e1-11
    • Keelan JA, Wong PM, Bird PS, Mitchell MD. Innate inflammatory responses of human decidual cells to periodontopathic bacteria. Am J Obstet Gynecol 2010;202(5). 471 e1-11.
    • (2010) Am J Obstet Gynecol , vol.202 , Issue.5 , pp. 471
    • Keelan, J.A.1    Wong, P.M.2    Bird, P.S.3    Mitchell, M.D.4
  • 42
    • 0022499383 scopus 로고
    • Adaption of the bicinchoninic acid protein assay for use with microtiter plates and sucrose gradient fractions
    • Redinbaugh MG, Turley RB. Adaption of the bicinchoninic acid protein assay for use with microtiter plates and sucrose gradient fractions. Anal Biochem 1986;153:267-71.
    • (1986) Anal Biochem , vol.153 , pp. 267-271
    • Redinbaugh, M.G.1    Turley, R.B.2
  • 43
    • 84865306307 scopus 로고    scopus 로고
    • Ceramide biosynthesis and metabolism in trophoblast syncytialization
    • Singh AT, Dharmarajan A, Aye IL, Keelan JA. Ceramide biosynthesis and metabolism in trophoblast syncytialization. Mol Cell Endocrinol 2012;362(1-2):48-59.
    • (2012) Mol Cell Endocrinol , vol.362 , Issue.1-2 , pp. 48-59
    • Singh, A.T.1    Dharmarajan, A.2    Aye, I.L.3    Keelan, J.A.4
  • 45
    • 84879524095 scopus 로고    scopus 로고
    • Long-term macrolide treatment for chronic respiratory disease
    • Spagnolo P, Fabbri LM, Bush A. Long-term macrolide treatment for chronic respiratory disease. Eur Resp J 2012;42(1):239-51.
    • (2012) Eur Resp J , vol.42 , Issue.1 , pp. 239-251
    • Spagnolo, P.1    Fabbri, L.M.2    Bush, A.3
  • 46
    • 85030400833 scopus 로고    scopus 로고
    • Solithromycin reduces inflammation in mice caused by bleomycin-induced lung injury
    • Abstract 42
    • Fernandes P, Hashiguchi T, Fujii M, Yoneyama H. Solithromycin reduces inflammation in mice caused by bleomycin-induced lung injury. Am J Crit Care Med 2014;189(Abstract 42):A6586.
    • (2014) Am J Crit Care Med , vol.189 , pp. A6586
    • Fernandes, P.1    Hashiguchi, T.2    Fujii, M.3    Yoneyama, H.4
  • 47
    • 84879019868 scopus 로고    scopus 로고
    • A novel macrolide/fluoroketolide, solithromycin (CEM-101), reverses corticosteroid insensitivity via phosphoinositide 3-kinase pathway inhibition
    • Kobayashi Y, Wada H, Rossios C, Takagi D, Charron C, Barnes PJ, et al. A novel macrolide/fluoroketolide, solithromycin (CEM-101), reverses corticosteroid insensitivity via phosphoinositide 3-kinase pathway inhibition. Br J Pharmacol 2013;169(5):1024-34.
    • (2013) Br J Pharmacol , vol.169 , Issue.5 , pp. 1024-1034
    • Kobayashi, Y.1    Wada, H.2    Rossios, C.3    Takagi, D.4    Charron, C.5    Barnes, P.J.6
  • 48
    • 70350613207 scopus 로고    scopus 로고
    • Toxic effects of low doses of bisphenol-A on human placental cells
    • Benachour N, Aris A. Toxic effects of low doses of bisphenol-A on human placental cells. Toxicol Appl Pharmacol 2009;241(3):322-8.
    • (2009) Toxicol Appl Pharmacol , vol.241 , Issue.3 , pp. 322-328
    • Benachour, N.1    Aris, A.2
  • 49
    • 33748144206 scopus 로고    scopus 로고
    • Experimental methods to study human transplacental exposure to genotoxic agents
    • Vahakangas K, Myllynen P. Experimental methods to study human transplacental exposure to genotoxic agents. Mutat Res 2006;608(2):129-35.
    • (2006) Mutat Res , vol.608 , Issue.2 , pp. 129-135
    • Vahakangas, K.1    Myllynen, P.2
  • 51
    • 77952334038 scopus 로고    scopus 로고
    • Prevention of inflammatory activation of human gestational membranes in an ex vivo model using a pharmacological NF-kappaB inhibitor
    • Keelan JA, Khan S, Yosaatmadja F, Mitchell MD. Prevention of inflammatory activation of human gestational membranes in an ex vivo model using a pharmacological NF-kappaB inhibitor. J Immunol 2009;183(8):5270-8.
    • (2009) J Immunol , vol.183 , Issue.8 , pp. 5270-5278
    • Keelan, J.A.1    Khan, S.2    Yosaatmadja, F.3    Mitchell, M.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.