Toxic effects of low doses of Bisphenol-A on human placental cells

Toxicology and Applied Pharmacology

Volumn 241, Issue 3, 2009, Pages 322-328

  Benachour, Nora ^a   Aris, Aziz ^a,b  

^a Laboratory of Research in Reproductive and Gestational Health   (Canada)

^b CENTRE HOSPITALIER UNIVERSITAIRE DE SHERBROOKE   (Canada)

Author keywords

Adenylate kinase; Apoptosis; Bisphenol A; Cytotrophoblasts; Human placenta; M30; Necrosis; TNF protein and mRNA

Indexed keywords

4,4' ISOPROPYLIDENEDIPHENOL; ADENYLATE CYCLASE; TUMOR NECROSIS FACTOR ALPHA;

ABORTION; APOPTOSIS; ARTICLE; CELL DAMAGE; CELL ISOLATION; CELL MEMBRANE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; CYTOTROPHOBLAST; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPOSURE; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN TISSUE; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; INTRAUTERINE GROWTH RETARDATION; NEWBORN; PLACENTA; PREECLAMPSIA; PREGNANT WOMAN; PREMATURITY; PROTEIN ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION;

ADENYLATE KINASE; ADULT; AIR POLLUTANTS, OCCUPATIONAL; APOPTOSIS; CELL MEMBRANE; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; PHENOLS; PLACENTA; PREGNANCY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TROPHOBLASTS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 70350613207     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2009.09.005     Document Type: Article

References (41)

1. Allaire A.D., Ballenger K.A., Wells S.R., McMahon M.J., and Lessey B.A. Placental apoptosis in preeclampsia. Obstet. Gynecol. 96 (2000) 271-276
2. Aris A., Leblanc S., Ouellet A., and Moutquin J.M. Detrimental effects of high levels of antioxidant vitamins C and E on placental function: considerations for the Vitamins in Preeclampsia (VIP) trial. J. Obstet. Gynaecol. Res. 34 (2008) 504-511
3. Benachour N., and Séralini G.E. Glyphosate formulations induce apoptosis and necrosis in human umbilical, embryonic, and placental cells. Chem. Res. Toxicol. 22 (2009) 97-105
4. Biles J.E., McNeal T.P., Begley T.H., and Hollifield H.C. Determination of bisphenol-A in reusable polycarbonate food-contact plastics and migration to food simulating liquids. J. Agric. Food Chem. 45 (1997) 3541-3544
5. Brock J.W., Yoshimura Y., Barr J.R., Maggio V.L., Graiser S.R., Nakazawa H., and Needham L.L. Measurement of bisphenol A levels in human urine. J. Expo. Anal. Environ. Epidemiol. 11 (2001) 323-328
6. Brotons J.A., Olea-Serrano M.F., Villalobos M., and Olea N. Xenoestrogens released from lacquer coating in food cans. Environ. Health Perspect. 103 (1994) 608-612
7. Chen H.L., Yang Y.P., Hu X.L., Yelavarthi K.K., Fishback J.L., and Hunt J.S. Tumor necrosis factor alpha mRNA and protein are present in human placental and uterine cells at early and late stages of gestation. Am. J. Pathol. 139 (1991) 327-335
8. Environment Canada, 2008. Proposed risk management approach for phenol, 4, 4′-(1-methylethylidene) bis (Bisphenol A). Chemical Abstract Service Registry Number (CAS RN 80-05-7). http://www.ec.gc.ca/substances/ese/eng/challenge/batch2/batch2_80-05-7.cfm. 2008.
9. Feron V.J., Cassee F.R., Groten J.P., van Vliet P.W., and van Zorge J.A. International issues on human health effects of exposure to chemical mixtures. Environ. Health Perspect. 110 (2002) 893-899
10. Guilbert L.J., and Winkler-Lowen B. Placental alkaline phosphatase (PLAP) staining and human chorionic gonadotropin (hCG) production in cultures of fresh and cryopreserved cytotrophoblasts isolated by CD9/MHC class I/MHC class II immunoelimination. Placenta 28 (2007) 348-349
11. Ikezuki Y., Tsutsumi O., Takai Y., Kamei Y., and Taketani Y. Determination of bisphenol A concentrations in human biological fluids reveals significant early prenatal exposure. Hum. Reprod. 17 (2002) 2839-2841
12. Kharfi A., Giguère Y., Sapin V., Massé J., Dastugue B., and Forest J.C. Trophoblastic remodeling in normal and preeclamptic pregnancies: implication of cytokines. Clin. Biochem. 36 (2003) 323-331
13. Kharfi A., Bureau M., Giguere Y., Moutquin J.M., and Forest J.C. Dissociation between increased apoptosis and expression of the tumor necrosis factor-alpha system in term placental villi with preeclampsia. Clin. Biochem. 39 (2006) 646-651
14. 2 on placental hCG secretion: implications for oxidative stress in preeclampsia. Clin. Biochem. 40 (2007) 94-97
15. Köhler C., Gahm A., Noma T., Nakazawa A., Orrenius S., and Zhivotovsky B. Release of adenylate kinase 2 from the mitochondrial intermembrane space during apoptosis. FEBS Lett. 447 (1999) 10-12
16. Kuo H.W., and Ding W.H. Trace determination of bisphenol A and phytoestrogens in infant formula powders by gas chromatography-mass spectrometry. J. Chromatogr. 1027 (2004) 67-74
17. Lee Y.J., Ryu H.Y., Kim H.K., Min C.S., Lee J.H., Kim E., Nam B.H., Park J.H., Jung J.Y., Jang D.D., Park E.Y., Lee K.H., Ma J.Y., Won H.S., Im M.W., Leem J.H., Hong Y.C., and Yoon H.S. Maternal and fetal exposure to bisphenol A in Korea. Reprod. Toxicol. 25 (2008) 413-419
18. Levy R., and Nelson D.M. To be, or not to be, that is the question. Apoptosis in human trophoblast. Placenta 21 (2000) 1-13
19. Li Y.J., Song T.B., Cai Y.Y., Zhou J.S., Song X., Zhao X., and Wu X.L. Bisphenol A exposure induces apoptosis and upregulation of Fas/FasL and caspase-3 expression in the testes of mice. Toxicol. Sci. 108 (2009) 427-436
20. Mayhew T.M., and Burton G.J. Methodological problems in placental morphometry: apologia for the use of stereology based on sound sampling practice. Placenta 9 (1988) 565-581
21. Myers J.P., vom Saal F.S., Akingbemi B.T., Arizono K., Belcher S., Colborn T., Chahoud I., Crain D.A., Farabollini F., Guillette Jr. L.J., Hassold T., Ho S.M., Hunt P.A., Iguchi T., Jobling S., Kanno J., Laufer H., Marcus M., McLachlan J.A., Nadal A., Oehlmann J., Olea N., Palanza P., Parmigiani S., Rubin B.S., Schoenfelder G., Sonnenschein C., Soto A.M., Talsness C.E., Taylor J.A., Vandenberg L.N., Vandenbergh J.G., Vogel S., Watson C.S., Welshons W.V., and Zoeller R.T. Why public health agencies cannot depend on good laboratory practices as a criterion for selecting data: the case of bisphenol A. Environ Health Perspect 117 (2009) 309-315
22. Munguia-Lopez E.M., Gerardo-Lugo S., Peralta E., Bolumen S., and Soto-Valdez H. Migration of bisphenol A (BPA) from can coatings into a fatty-food stimulant and tuna fish. Food Addit. Contam. 22 (2005) 892-898
23. Munoz de Toro M.M., Markey C.M., Wadia P.R., Luque E.H., Rubin B.S., Sonnenschein C., and Soto A.M. Perinatal exposure to Bisphenol A alters peripubertal mammary gland development in mice. Endocrinology 146 (2005) 4138-4147
24. Noma T. Dynamics of nucleotide metabolism as a supporter of life phenomena. J. Med. Invest. 52 (2005) 127-136
25. Padmanabhan V., Siefert K., Ransom S., Johnson T., Pinkerton J., Anderson L., Tao L., and Kannan K. Maternal bisphenol-A levels at delivery: a looming problem?. J. Perinatol. 28 (2008) 258-263
26. Pfaffl M.W. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 29 (2001) 2002-2007
27. Schonfelder G., Wittfoht W., Hopp H., Talsness C.E., Paul M., and Chahoud I. Parent bisphenol A accumulation in the human maternal-fetal-placental unit. Environ. Health Perspect. 110 (2002) A703-A707
28. Sharpe R.M., and Skakkebaek N.E. Are oestrogens involved in falling sperm count and disorders of the male reproductive tract?. Lancet 341 (1993) 1392-1395
29. Skakkebaek N.E., Meyts E.R., Jorgensen N., Carlsen E., Petersen P.M., Giwercman A., Andersen A.G., Jensen T.K., Andersson A.M., and Müller J. Germ cell cancer and disorders of spermatogenesis: an environmental connection?. APMIS 106 (1998) 3-11
30. Smith S.C., Baker P.N., and Symonds E.M. Increased placental apoptosis in intrauterine growth restriction. Am. J. Obstet. Gynecol. 177 (1997) 1395-1401
31. Squirrell D., and Murphy J. Rapid detection of very low numbers of micro-organisms using adenylate kinase as a cell marker. A practical guide to industrial uses of ATP luminescence in rapid microbiology (1997) 107-113
32. Taatjes D.J., Sobel B.E., and Budd R.C. Morphological and cytochemical determination of cell death by apoptosis. Histochem. Cell Biol. 129 (2008) 33-43
33. Takahashi O., and Oishi S. Disposition of orally administered 2,2-bis(4-hydroxyphenyl) propane (bisphenol A) in pregnant rats and placental transfer to fetuses. Environ. Health. Perspect. 108 (2000) 931-935
34. Thomson B.M., and Grounds P.R. Bisphenol A in canned foods in New Zealand: an exposure assessment. Food Addit. Contam. 22 (2005) 65-72
35. Uchida K., Suzuki A., Kobayashi Y., Watanabe H., Katsu Y., and Suzuki J. Bisphenol A administration during pregnancy results in fetal exposure in mice and monkeys. J. Health Sci. 48 (2002) 579-582
36. US National Toxicology Program, 2008. Draft NTP brief on bisphenol A (CAS NO 80-05-7). http://cerhr.niehs.nih.gov/chemicals/bisphenol/BPADraftBriefVF_04_14_08.pdf, pp. 1-68.
37. Vandenberg L.N., Hauser R., Marcus M., Olea N., and Welshons W.V. Human exposure to bisphenol A (BPA). Reprod. Toxicol. 24 (2007) 139-177
38. Vandenberg L.N., Maffini M.V., Schaeberle C.M., Ucci A.A., Sonnenschein C., Rubin B.S., and Soto A.M. Perinatal exposure to the xenoestrogen bisphenol-A induces mammary intraductal hyperplasias in adult CD-1 mice. Reprod. Toxicol. 26 (2008) 210-219
39. vom Saal F.S., Akingbemi B.T., Belcher S.M., Birnbaum L.S., Crain D.A., Eriksen M., Farabollini F., Guillette L.J., Hauser R., Heindel J.J., Ho S.M., Hunt P.A., Iguchi T., Jobling S., Kanno J., Keri R.A., Knudsen K.E., Laufer H., LeBlanc G.A., Marcus M., McLachlan J.A., Myers J.P., Nadal A., Newbold R.R., Olea N., Prins G.S., Richter C.A., Rubin B.S., Sonnenschein C., Soto A.M., Talsness C.E., Vandenbergh J.G., Vandenberg L.N., Walser-Kuntz D.R., Watson C.S., Welshons W.V., Wetherill Y., and Zoeller R.T. Chapel Hill bisphenol A expert panel consensus statement: integration of mechanisms, effects in animals and potential to impact human health at current levels of exposure. Reprod. Toxicol. 24 (2007) 131-138
40. Wolfgang D., and Wolfgang V. Human exposure to bisphenol A by biomonitoring: methods, results and assessment of environmental exposures. Toxicol. Appl. Pharmacol. 228 (2008) 114-134
41. Yamada H., Furuta I., Kato E.H., Kataoka S., Usuki Y., Kobashi G., Sata F., Kishi R., and Fujimoto S. Maternal serum and amniotic fluid bisphenol A concentrations in the early second trimester. Reprod. Toxicol. 16 (2002) 735-739