The human placental perfusion model: A systematic review and development of a model to predict in vivo transfer of therapeutic drugs

Clinical Pharmacology and Therapeutics

Volumn 90, Issue 1, 2011, Pages 67-76

  Hutson, J R ^a,b   Garcia Bournissen, F ^a,b   Davis, A ^a   Koren, G ^a,b  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ACICLOVIR; ALFENTANIL; ATENOLOL; AZITHROMYCIN; BUPIVACAINE; BUPRENORPHINE; CARBAMAZEPINE; CELIPROLOL; CIMETIDINE; CITALOPRAM; CLONIDINE; DICLOFENAC; DIGOXIN; ENALAPRILAT; ENFUVIRTIDE; ERYTHROMYCIN; FLUOXETINE; FONDAPARINUX; GLIBENCLAMIDE; HEPARIN; INDINAVIR; INSULIN LISPRO; LOW MOLECULAR WEIGHT HEPARIN; METFORMIN; OXCARBAZEPINE; PARACETAMOL; ROPIVACAINE; SAQUINAVIR; UNINDEXED DRUG;

ADULT; COMPARATIVE STUDY; DATA ANALYSIS; DELIVERY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG PROTEIN BINDING; EXPERIMENTAL MODEL; FETUS; GESTATIONAL AGE; HUMAN; MATERNAL BLOOD; MEMBRANE VESICLE; NONHUMAN; PLACENTA PERFUSION; PLACENTAL TRANSFER; PREDICTION; PREGNANCY; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; REVIEW; RISK BENEFIT ANALYSIS; SYSTEMATIC REVIEW; TROPHOBLAST; UMBILICAL CORD BLOOD;

ADULT; DATA INTERPRETATION, STATISTICAL; FEMALE; FETAL BLOOD; HUMANS; INFANT, NEWBORN; MATERNAL-FETAL EXCHANGE; MODELS, BIOLOGICAL; MODELS, STATISTICAL; PERFUSION; PHARMACEUTICAL PREPARATIONS; PLACENTA; PREGNANCY; REGIONAL BLOOD FLOW;

EID: 79959377520     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/clpt.2011.66     Document Type: Review

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