Structural insights into mis-regulation of protein kinase a in human tumors

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 5, 2015, Pages 1374-1379

  Cheung, Jonah ^a   Ginter, Christopher ^a   Cassidy, Michael ^a   Franklin, Matthew C ^a   Rudolph, Michael J ^a   Robine, Nicolas ^b   Darnell, Robert B ^b,c,d   Hendrickson, Wayne A ^a  

^a NEW YORK STRUCTURAL BIOLOGY CENTER   (United States)

^b NEW YORK GENOME CENTER   (United States)

^c ROCKEFELLER UNIVERSITY   (United States)

^d Howard Hughes Medical Institute   (United States)

Author keywords

Cancer mutations; Chimeric protein; Cushing's syndrome; Fibrolamelllar hepatocellular carcinoma

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE;

ARTICLE; CARCINOGENESIS; CELL PROLIFERATION; CHIMERA; CONTROLLED STUDY; CUSHING SYNDROME; HUMAN; HUMAN CELL; METABOLISM; MUTATION; NEOPLASM; PRIORITY JOURNAL; PROMOTER REGION; CHEMICAL STRUCTURE; CHEMISTRY; CRYSTALLIZATION; DIMERIZATION; ENZYME ACTIVE SITE; ENZYMOLOGY; GENETICS; PROTEIN CONFORMATION; SIZE EXCLUSION CHROMATOGRAPHY; SURFACE PLASMON RESONANCE;

CATALYTIC DOMAIN; CHROMATOGRAPHY, GEL; CRYSTALLIZATION; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DIMERIZATION; HUMANS; MODELS, MOLECULAR; MUTATION; NEOPLASMS; PROTEIN CONFORMATION; SURFACE PLASMON RESONANCE;

EID: 84922294268     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1424206112     Document Type: Article

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