-
1
-
-
34250020201
-
Hepatocellular carcinoma: epidemiology and molecular carcinogenesis
-
El-Serag, H.B. and Rudolph, K.L. (2007) Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology, 132, 2557-2576.
-
(2007)
Gastroenterology
, vol.132
, pp. 2557-2576
-
-
El-Serag, H.B.1
Rudolph, K.L.2
-
2
-
-
84873020277
-
Pathogenic mechanisms in HBV- and HCV-associated hepatocellular carcinoma
-
Arzumanyan, A., Reis, H.M. and Feitelson, M.A. (2013) Pathogenic mechanisms in HBV- and HCV-associated hepatocellular carcinoma. Nat. Rev. Cancer, 13, 123-135.
-
(2013)
Nat. Rev. Cancer
, vol.13
, pp. 123-135
-
-
Arzumanyan, A.1
Reis, H.M.2
Feitelson, M.A.3
-
3
-
-
25844484569
-
Primary liver carcinoma arising in people younger than 30 years
-
Klein, W.M., Molmenti, E.P., Colombani, P.M., Grover, D.S., Schwarz, K.B., Boitnott, J. and Torbenson, M.S. (2005) Primary liver carcinoma arising in people younger than 30 years. Am. J. Clin. Pathol., 124, 512-518.
-
(2005)
Am. J. Clin. Pathol.
, vol.124
, pp. 512-518
-
-
Klein, W.M.1
Molmenti, E.P.2
Colombani, P.M.3
Grover, D.S.4
Schwarz, K.B.5
Boitnott, J.6
Torbenson, M.S.7
-
4
-
-
79951918659
-
Fibrolamellar carcinoma: a review with focus on genetics and comparison to other malignant primary liver tumors
-
Ward, S.C. and Waxman, S. (2011) Fibrolamellar carcinoma: a review with focus on genetics and comparison to other malignant primary liver tumors. Semin. Liver Dis., 31, 61-70.
-
(2011)
Semin. Liver Dis.
, vol.31
, pp. 61-70
-
-
Ward, S.C.1
Waxman, S.2
-
5
-
-
1542724808
-
Is fibrolamellar carcinoma different from hepatocellular carcinoma? A US population-based study
-
El-Serag, H.B. and Davila, J.A. (2004) Is fibrolamellar carcinoma different from hepatocellular carcinoma? A US population-based study. Hepatology, 39, 798-803.
-
(2004)
Hepatology
, vol.39
, pp. 798-803
-
-
El-Serag, H.B.1
Davila, J.A.2
-
6
-
-
27144486411
-
Clinicopathologic features and survival in fibrolamellar carcinoma: comparison with conventional hepatocellular carcinoma with and without cirrhosis
-
Kakar, S., Burgart, L.J., Batts, K.P., Garcia, J., Jain, D. and Ferrell, L.D. (2005) Clinicopathologic features and survival in fibrolamellar carcinoma: comparison with conventional hepatocellular carcinoma with and without cirrhosis. Mod. Pathol., 18, 1417-1423.
-
(2005)
Mod. Pathol.
, vol.18
, pp. 1417-1423
-
-
Kakar, S.1
Burgart, L.J.2
Batts, K.P.3
Garcia, J.4
Jain, D.5
Ferrell, L.D.6
-
7
-
-
0018829934
-
Fibrolamellar carcinoma of the liver: a tumor of adolescents and young adults with distinctive clinico-pathologic features
-
Craig, J.R., Peters, R.L., Edmondson, H.A. and Omata, M. (1980) Fibrolamellar carcinoma of the liver: a tumor of adolescents and young adults with distinctive clinico-pathologic features. Cancer, 46, 372-379.
-
(1980)
Cancer
, vol.46
, pp. 372-379
-
-
Craig, J.R.1
Peters, R.L.2
Edmondson, H.A.3
Omata, M.4
-
8
-
-
70350492933
-
Fibrolamellar hepatocellular carcinoma
-
quiz 2625
-
Liu, S., Chan, K.W., Wang, B. and Qiao, L. (2009) Fibrolamellar hepatocellular carcinoma. Am. J. Gastroenterol., 104, 2617-2624. quiz 2625.
-
(2009)
Am. J. Gastroenterol.
, vol.104
, pp. 2617-2624
-
-
Liu, S.1
Chan, K.W.2
Wang, B.3
Qiao, L.4
-
9
-
-
40449099255
-
EpCAM and alpha-fetoprotein expression defines novel prognostic subtypes of hepatocellular carcinoma
-
Yamashita, T., Forgues, M., Wang,W., Kim, J.W., Ye, Q., Jia, H., Budhu, A., Zanetti, K.A., Chen, Y., Qin, L.X. et al. (2008) EpCAM and alpha-fetoprotein expression defines novel prognostic subtypes of hepatocellular carcinoma. Cancer Res., 68, 1451-1461.
-
(2008)
Cancer Res.
, vol.68
, pp. 1451-1461
-
-
Yamashita, T.1
Forgues, M.2
Wang, W.3
Kim, J.W.4
Ye, Q.5
Jia, H.6
Budhu, A.7
Zanetti, K.A.8
Chen, Y.9
Qin, L.X.10
-
10
-
-
77956295659
-
Fibrolamellar carcinoma of the liver exhibits immunohistochemical evidence of both hepatocyte and bile duct differentiation
-
Ward, S.C., Huang, J., Tickoo, S.K., Thung, S.N., Ladanyi, M. and Klimstra, D.S. (2010) Fibrolamellar carcinoma of the liver exhibits immunohistochemical evidence of both hepatocyte and bile duct differentiation. Mod. Pathol., 23, 1180-1190.
-
(2010)
Mod. Pathol.
, vol.23
, pp. 1180-1190
-
-
Ward, S.C.1
Huang, J.2
Tickoo, S.K.3
Thung, S.N.4
Ladanyi, M.5
Klimstra, D.S.6
-
11
-
-
79952195361
-
Fibrolamellar carcinomas are positive for CD68
-
Ross, H.M., Daniel, H.D., Vivekanandan, P., Kannangai, R., Yeh, M.M., Wu, T.T., Makhlouf, H.R. and Torbenson, M. (2011) Fibrolamellar carcinomas are positive for CD68. Mod. Pathol., 24, 390-395.
-
(2011)
Mod. Pathol.
, vol.24
, pp. 390-395
-
-
Ross, H.M.1
Daniel, H.D.2
Vivekanandan, P.3
Kannangai, R.4
Yeh, M.M.5
Wu, T.T.6
Makhlouf, H.R.7
Torbenson, M.8
-
12
-
-
84876121571
-
Sal-like protein 4 (SALL4), a stem cell biomarker in liver cancers
-
Oikawa, T., Kamiya, A., Zeniya, M., Chikada, H., Hyuck, A.D., Yamazaki, Y., Wauthier, E., Tajiri, H., Miller, L.D., Wang, X.W. et al. (2013) Sal-like protein 4 (SALL4), a stem cell biomarker in liver cancers. Hepatology, 57, 1469-1483.
-
(2013)
Hepatology
, vol.57
, pp. 1469-1483
-
-
Oikawa, T.1
Kamiya, A.2
Zeniya, M.3
Chikada, H.4
Hyuck, A.D.5
Yamazaki, Y.6
Wauthier, E.7
Tajiri, H.8
Miller, L.D.9
Wang, X.W.10
-
13
-
-
0025163937
-
Abundant expression of cytokeratin 7 in fibrolamellar carcinoma of the liver
-
Van Eyken, P., Sciot, R., Brock, P., Casteels-Van Daele, M., Ramaekers, F.C. and Desmet, V.J. (1990) Abundant expression of cytokeratin 7 in fibrolamellar carcinoma of the liver. Histopathology, 17, 101-107.
-
(1990)
Histopathology
, vol.17
, pp. 101-107
-
-
Van Eyken, P.1
Sciot, R.2
Brock, P.3
Casteels-Van Daele, M.4
Ramaekers, F.C.5
Desmet, V.J.6
-
14
-
-
33947149044
-
Fibrolamellar carcinomas show overexpression of genes in the RAS, MAPK, PIK3, and xenobiotic degradation pathways
-
Kannangai, R., Vivekanandan, P., Martinez-Murillo, F., Choti, M. and Torbenson, M. (2007) Fibrolamellar carcinomas show overexpression of genes in the RAS, MAPK, PIK3, and xenobiotic degradation pathways. Hum. Pathol., 38, 639-644.
-
(2007)
Hum. Pathol.
, vol.38
, pp. 639-644
-
-
Kannangai, R.1
Vivekanandan, P.2
Martinez-Murillo, F.3
Choti, M.4
Torbenson, M.5
-
15
-
-
33645116622
-
Epidermal growth factor receptor expression and gene copy number in fibrolamellar hepatocellular carcinoma
-
Buckley, A.F., Burgart, L.J. and Kakar, S. (2006) Epidermal growth factor receptor expression and gene copy number in fibrolamellar hepatocellular carcinoma. Hum. Pathol., 37, 410-414.
-
(2006)
Hum. Pathol.
, vol.37
, pp. 410-414
-
-
Buckley, A.F.1
Burgart, L.J.2
Kakar, S.3
-
16
-
-
63349098247
-
Unique phenotype of hepatocellular cancers with exon-3 mutations in beta-catenin gene
-
Cieply, B., Zeng, G., Proverbs-Singh, T., Geller, D.A. and Monga, S.P. (2009) Unique phenotype of hepatocellular cancers with exon-3 mutations in beta-catenin gene. Hepatology, 49, 821-831.
-
(2009)
Hepatology
, vol.49
, pp. 821-831
-
-
Cieply, B.1
Zeng, G.2
Proverbs-Singh, T.3
Geller, D.A.4
Monga, S.P.5
-
17
-
-
0030762644
-
Lamellar fibrosis in the fibrolamellar variant of hepatocellular carcinoma: a role for transforming growth factor beta
-
Orsatti, G., Hytiroglou, P., Thung, S.N., Ishak, K.G. and Paronetto, F. (1997) Lamellar fibrosis in the fibrolamellar variant of hepatocellular carcinoma: a role for transforming growth factor beta. Liver, 17, 152-156.
-
(1997)
Liver
, vol.17
, pp. 152-156
-
-
Orsatti, G.1
Hytiroglou, P.2
Thung, S.N.3
Ishak, K.G.4
Paronetto, F.5
-
18
-
-
77953423408
-
Constitutive activation of nuclear factor-kappa B (NF-kB) signaling pathway in fibrolamellar hepatocellular carcinoma
-
Li, W., Tan, D., Zenali, M.J. and Brown, R.E. (2010) Constitutive activation of nuclear factor-kappa B (NF-kB) signaling pathway in fibrolamellar hepatocellular carcinoma. Int. J. Clin. Exp. Pathol., 3, 238-243.
-
(2010)
Int. J. Clin. Exp. Pathol.
, vol.3
, pp. 238-243
-
-
Li, W.1
Tan, D.2
Zenali, M.J.3
Brown, R.E.4
-
19
-
-
84856090070
-
Loss of the orphan nuclear receptor SHP is more pronounced in fibrolamellar carcinoma than in typical hepatocellular carcinoma
-
Wilczek, E., Szparecki, G., Lukasik, D., Koperski, L., Winiarska, M., Wilczynski, G.M., Wasiutynski, A. and Gornicka, B. (2012) Loss of the orphan nuclear receptor SHP is more pronounced in fibrolamellar carcinoma than in typical hepatocellular carcinoma. PLoS ONE, 7, e30944.
-
(2012)
PLoS ONE
, vol.7
, pp. e30944
-
-
Wilczek, E.1
Szparecki, G.2
Lukasik, D.3
Koperski, L.4
Winiarska, M.5
Wilczynski, G.M.6
Wasiutynski, A.7
Gornicka, B.8
-
20
-
-
84899838345
-
Prognosis of patients with fibrolamellar hepatocellular carcinoma versus conventional hepatocellular carcinoma: a systematic review and meta-analysis
-
Njei, B., Konjeti, V.R. and Ditah, I. (2014) Prognosis of patients with fibrolamellar hepatocellular carcinoma versus conventional hepatocellular carcinoma: a systematic review and meta-analysis. Gastrointest. Cancer Res., 7, 49-54.
-
(2014)
Gastrointest. Cancer Res.
, vol.7
, pp. 49-54
-
-
Njei, B.1
Konjeti, V.R.2
Ditah, I.3
-
21
-
-
0028912086
-
Fibrolamellar hepatocellular carcinoma: stage at presentation and results of aggressive surgical management
-
Stevens, W.R., Johnson, C.D., Stephens, D.H. and Nagorney, D.M. (1995) Fibrolamellar hepatocellular carcinoma: stage at presentation and results of aggressive surgical management. AJR Am. J. Roentgenol., 164, 1153-1158.
-
(1995)
AJR Am. J. Roentgenol.
, vol.164
, pp. 1153-1158
-
-
Stevens, W.R.1
Johnson, C.D.2
Stephens, D.H.3
Nagorney, D.M.4
-
22
-
-
0344407445
-
Fibrolamellar hepatocellular carcinoma in children and adolescents
-
Katzenstein, H.M., Krailo, M.D., Malogolowkin, M.H., Ortega, J.A., Qu, W., Douglass, E.C., Feusner, J.H., Reynolds, M., Quinn, J.J., Newman, K. et al. (2003) Fibrolamellar hepatocellular carcinoma in children and adolescents. Cancer, 97, 2006-2012.
-
(2003)
Cancer
, vol.97
, pp. 2006-2012
-
-
Katzenstein, H.M.1
Krailo, M.D.2
Malogolowkin, M.H.3
Ortega, J.A.4
Qu, W.5
Douglass, E.C.6
Feusner, J.H.7
Reynolds, M.8
Quinn, J.J.9
Newman, K.10
-
23
-
-
84875648121
-
Clinicopathologic characteristics and survival outcomes of patients with fibrolamellar carcinoma: data from the fibrolamellar carcinoma consortium
-
Ang, C.S., Kelley, R.K., Choti, M.A., Cosgrove, D.P., Chou, J.F., Klimstra, D., Torbenson, M.S., Ferrell, L., Pawlik, T.M., Fong, Y. et al. (2013) Clinicopathologic characteristics and survival outcomes of patients with fibrolamellar carcinoma: data from the fibrolamellar carcinoma consortium. Gastrointest. Cancer Res., 6, 3-9.
-
(2013)
Gastrointest. Cancer Res.
, vol.6
, pp. 3-9
-
-
Ang, C.S.1
Kelley, R.K.2
Choti, M.A.3
Cosgrove, D.P.4
Chou, J.F.5
Klimstra, D.6
Torbenson, M.S.7
Ferrell, L.8
Pawlik, T.M.9
Fong, Y.10
-
24
-
-
84868314554
-
Fibrolamellar variant of hepatocellular carcinoma
-
Chun, Y.S. and Zimmitti, G. (2013) Fibrolamellar variant of hepatocellular carcinoma. Recent Results Cancer Res., 190, 101-110.
-
(2013)
Recent Results Cancer Res.
, vol.190
, pp. 101-110
-
-
Chun, Y.S.1
Zimmitti, G.2
-
25
-
-
84896732099
-
Detection of a recurrent DNAJB1-PRKACA chimeric transcript in fibrolamellar hepatocellular carcinoma
-
Honeyman, J.N., Simon, E.P., Robine, N., Chiaroni-Clarke, R., Darcy, D.G., Lim, I.I., Gleason, C.E., Murphy, J.M., Rosenberg, B.R., Teegan, L. et al. (2014) Detection of a recurrent DNAJB1-PRKACA chimeric transcript in fibrolamellar hepatocellular carcinoma. Science, 343, 1010-1014.
-
(2014)
Science
, vol.343
, pp. 1010-1014
-
-
Honeyman, J.N.1
Simon, E.P.2
Robine, N.3
Chiaroni-Clarke, R.4
Darcy, D.G.5
Lim, I.I.6
Gleason, C.E.7
Murphy, J.M.8
Rosenberg, B.R.9
Teegan, L.10
-
26
-
-
59049098400
-
Anterior gradient-2 is overexpressed by fibrolamellar carcinomas
-
Vivekanandan, P., Micchelli, S.T. and Torbenson, M. (2009) Anterior gradient-2 is overexpressed by fibrolamellar carcinomas. Hum. Pathol., 40, 293-299.
-
(2009)
Hum. Pathol.
, vol.40
, pp. 293-299
-
-
Vivekanandan, P.1
Micchelli, S.T.2
Torbenson, M.3
-
27
-
-
0021332874
-
Neurotensin secretion by fibrolamellar carcinoma of the liver
-
Collier, N.A., Weinbren, K., Bloom, S.R., Lee, Y.C., Hodgson, H.J. and Blumgart, L.H. (1984) Neurotensin secretion by fibrolamellar carcinoma of the liver. Lancet, 1, 538-540.
-
(1984)
Lancet
, vol.1
, pp. 538-540
-
-
Collier, N.A.1
Weinbren, K.2
Bloom, S.R.3
Lee, Y.C.4
Hodgson, H.J.5
Blumgart, L.H.6
-
28
-
-
0026030399
-
'Neuroendocrine' differentiation in primary neoplasms of the liver
-
Wang, J.H., Dhillon, A.P., Sankey, E.A., Wightman, A.K., Lewin, J.F. and Scheuer, P.J. (1991) 'Neuroendocrine' differentiation in primary neoplasms of the liver. J. Pathol., 163, 61-67.
-
(1991)
J. Pathol.
, vol.163
, pp. 61-67
-
-
Wang, J.H.1
Dhillon, A.P.2
Sankey, E.A.3
Wightman, A.K.4
Lewin, J.F.5
Scheuer, P.J.6
-
29
-
-
84901427888
-
Transcriptional profiling of pure fibrolamellar hepatocellular carcinoma reveals an endocrine signature
-
Malouf, G.G., Job, S., Paradis, V., Fabre, M., Brugieres, L., Saintigny, P., Vescovo, L., Belghiti, J., Branchereau, S., Faivre, S. et al. (2014) Transcriptional profiling of pure fibrolamellar hepatocellular carcinoma reveals an endocrine signature. Hepatology, 59, 2228-2237.
-
(2014)
Hepatology
, vol.59
, pp. 2228-2237
-
-
Malouf, G.G.1
Job, S.2
Paradis, V.3
Fabre, M.4
Brugieres, L.5
Saintigny, P.6
Vescovo, L.7
Belghiti, J.8
Branchereau, S.9
Faivre, S.10
-
30
-
-
0027499841
-
Infrequent chromosome allele loss in fibrolamellar carcinoma
-
Ding, S.F., Delhanty, J.D., Bowles, L., Dooley, J.S., Wood, C.B. and Habib, N.A. (1993) Infrequent chromosome allele loss in fibrolamellar carcinoma. Br. J. Cancer, 67, 244-246.
-
(1993)
Br. J. Cancer
, vol.67
, pp. 244-246
-
-
Ding, S.F.1
Delhanty, J.D.2
Bowles, L.3
Dooley, J.S.4
Wood, C.B.5
Habib, N.A.6
-
31
-
-
84861625981
-
Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma
-
Guichard, C., Amaddeo, G., Imbeaud, S., Ladeiro, Y., Pelletier, L., Maad, I.B., Calderaro, J., Bioulac-Sage, P., Letexier, M., Degos, F. et al. (2012) Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma. Nat. Genet., 44, 694-698.
-
(2012)
Nat. Genet.
, vol.44
, pp. 694-698
-
-
Guichard, C.1
Amaddeo, G.2
Imbeaud, S.3
Ladeiro, Y.4
Pelletier, L.5
Maad, I.B.6
Calderaro, J.7
Bioulac-Sage, P.8
Letexier, M.9
Degos, F.10
-
32
-
-
84862976633
-
Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators
-
Fujimoto, A., Totoki, Y., Abe, T., Boroevich, K.A., Hosoda, F., Nguyen, H.H., Aoki, M., Hosono, N., Kubo, M., Miya, F. et al. (2012) Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators. Nat. Genet., 44, 760-764.
-
(2012)
Nat. Genet.
, vol.44
, pp. 760-764
-
-
Fujimoto, A.1
Totoki, Y.2
Abe, T.3
Boroevich, K.A.4
Hosoda, F.5
Nguyen, H.H.6
Aoki, M.7
Hosono, N.8
Kubo, M.9
Miya, F.10
-
33
-
-
84866868120
-
Exome sequencing of hepatitis B virus-associated hepatocellular carcinoma
-
Huang, J., Deng, Q., Wang, Q., Li, K.Y., Dai, J.H., Li, N., Zhu, Z.D., Zhou, B., Liu, X.Y., Liu, R.F. et al. (2012) Exome sequencing of hepatitis B virus-associated hepatocellular carcinoma. Nat. Genet., 44, 1117-1121.
-
(2012)
Nat. Genet.
, vol.44
, pp. 1117-1121
-
-
Huang, J.1
Deng, Q.2
Wang, Q.3
Li, K.Y.4
Dai, J.H.5
Li, N.6
Zhu, Z.D.7
Zhou, B.8
Liu, X.Y.9
Liu, R.F.10
-
34
-
-
84875490185
-
Cancer genome landscapes
-
Vogelstein, B., Papadopoulos, N., Velculescu, V.E., Zhou, S., Diaz, L.A. Jr. and Kinzler, K.W. (2013) Cancer genome landscapes. Science, 339, 1546-1558.
-
(2013)
Science
, vol.339
, pp. 1546-1558
-
-
Vogelstein, B.1
Papadopoulos, N.2
Velculescu, V.E.3
Zhou, S.4
Diaz, L.A.5
Kinzler, K.W.6
-
35
-
-
0034601378
-
Distinct chromosomal abnormality pattern in primary liver cancer of non-B, non-C patients
-
Marchio, A., Pineau, P., Meddeb, M., Terris, B., Tiollais, P., Bernheim, A. and Dejean, A. (2000) Distinct chromosomal abnormality pattern in primary liver cancer of non-B, non-C patients. Oncogene, 19, 3733-3738.
-
(2000)
Oncogene
, vol.19
, pp. 3733-3738
-
-
Marchio, A.1
Pineau, P.2
Meddeb, M.3
Terris, B.4
Tiollais, P.5
Bernheim, A.6
Dejean, A.7
-
36
-
-
0034525791
-
Cytogenetic aberrations in primary and recurrent fibrolamellar hepatocellular carcinoma detected by comparative genomic hybridization
-
Wilkens, L., Bredt, M., Flemming, P., Kubicka, S., Klempnauer, J. and Kreipe, H. (2000) Cytogenetic aberrations in primary and recurrent fibrolamellar hepatocellular carcinoma detected by comparative genomic hybridization. Am. J. Clin. Pathol., 114, 867-874.
-
(2000)
Am. J. Clin. Pathol.
, vol.114
, pp. 867-874
-
-
Wilkens, L.1
Bredt, M.2
Flemming, P.3
Kubicka, S.4
Klempnauer, J.5
Kreipe, H.6
-
37
-
-
0026529566
-
Intracellular localization and partial amino acid sequence of a stress-inducible 40-kDa protein in HeLa cells
-
Hattori, H., Liu, Y.C., Tohnai, I., Ueda, M., Kaneda, T., Kobayashi, T., Tanabe, K. and Ohtsuka, K. (1992) Intracellular localization and partial amino acid sequence of a stress-inducible 40-kDa protein in HeLa cells. Cell Struct. Funct., 17, 77-86.
-
(1992)
Cell Struct. Funct.
, vol.17
, pp. 77-86
-
-
Hattori, H.1
Liu, Y.C.2
Tohnai, I.3
Ueda, M.4
Kaneda, T.5
Kobayashi, T.6
Tanabe, K.7
Ohtsuka, K.8
-
38
-
-
31144458770
-
Oscillations of cyclic AMP in hormone-stimulated insulin-secreting beta-cells
-
Dyachok, O., Isakov, Y., Sagetorp, J. and Tengholm, A. (2006) Oscillations of cyclic AMP in hormone-stimulated insulin-secreting beta-cells. Nature, 439, 349-352.
-
(2006)
Nature
, vol.439
, pp. 349-352
-
-
Dyachok, O.1
Isakov, Y.2
Sagetorp, J.3
Tengholm, A.4
-
39
-
-
59149091340
-
Sequence variants at theTERT-CLPTM1Llocus associate withmanycancer types
-
Rafnar, T., Sulem, P., Stacey, S.N., Geller, F., Gudmundsson, J., Sigurdsson, A., Jakobsdottir, M., Helgadottir, H., Thorlacius, S., Aben, K.K. et al. (2009) Sequence variants at theTERT-CLPTM1Llocus associate withmanycancer types. Nat. Genet., 41, 221-227.
-
(2009)
Nat. Genet.
, vol.41
, pp. 221-227
-
-
Rafnar, T.1
Sulem, P.2
Stacey, S.N.3
Geller, F.4
Gudmundsson, J.5
Sigurdsson, A.6
Jakobsdottir, M.7
Helgadottir, H.8
Thorlacius, S.9
Aben, K.K.10
-
40
-
-
33745268851
-
Mutations in GLIS3 are responsible for a rare syndrome with neonatal diabetes mellitus and congenital hypothyroidism
-
Senee, V., Chelala, C., Duchatelet, S., Feng, D., Blanc, H., Cossec, J.C., Charon, C., Nicolino, M., Boileau, P., Cavener, D.R. et al. (2006) Mutations in GLIS3 are responsible for a rare syndrome with neonatal diabetes mellitus and congenital hypothyroidism. Nat. Genet., 38, 682-687.
-
(2006)
Nat. Genet.
, vol.38
, pp. 682-687
-
-
Senee, V.1
Chelala, C.2
Duchatelet, S.3
Feng, D.4
Blanc, H.5
Cossec, J.C.6
Charon, C.7
Nicolino, M.8
Boileau, P.9
Cavener, D.R.10
-
41
-
-
64749094310
-
The cancer genome
-
Stratton, M.R., Campbell, P.J. and Futreal, P.A. (2009) The cancer genome. Nature, 458, 719-724.
-
(2009)
Nature
, vol.458
, pp. 719-724
-
-
Stratton, M.R.1
Campbell, P.J.2
Futreal, P.A.3
-
42
-
-
33947581390
-
The impact of translocations and gene fusions on cancer causation
-
Mitelman, F., Johansson, B. and Mertens, F. (2007) The impact of translocations and gene fusions on cancer causation. Nat. Rev. Cancer, 7, 233-245.
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 233-245
-
-
Mitelman, F.1
Johansson, B.2
Mertens, F.3
-
43
-
-
84897440556
-
The prenatal origins of cancer
-
Marshall, G.M., Carter, D.R., Cheung, B.B., Liu, T., Mateos, M.K., Meyerowitz, J.G. and Weiss, W.A. (2014) The prenatal origins of cancer. Nat. Rev. Cancer, 14, 277-289.
-
(2014)
Nat. Rev. Cancer
, vol.14
, pp. 277-289
-
-
Marshall, G.M.1
Carter, D.R.2
Cheung, B.B.3
Liu, T.4
Mateos, M.K.5
Meyerowitz, J.G.6
Weiss, W.A.7
-
44
-
-
84862777113
-
A novel retinoblastoma therapy from genomic and epigenetic analyses
-
Zhang, J., Benavente, C.A., McEvoy, J., Flores-Otero, J., Ding, L., Chen, X., Ulyanov, A., Wu, G., Wilson, M., Wang, J. et al. (2012) A novel retinoblastoma therapy from genomic and epigenetic analyses. Nature, 481, 329-334.
-
(2012)
Nature
, vol.481
, pp. 329-334
-
-
Zhang, J.1
Benavente, C.A.2
McEvoy, J.3
Flores-Otero, J.4
Ding, L.5
Chen, X.6
Ulyanov, A.7
Wu, G.8
Wilson, M.9
Wang, J.10
-
45
-
-
0027091627
-
Clinical significance of the BCR-ABL fusion gene in adult acute lymphoblastic leukemia: a Cancer and Leukemia Group B Study (8762)
-
Westbrook, C.A., Hooberman, A.L., Spino, C., Dodge, R.K., Larson, R.A., Davey, F., Wurster-Hill, D.H., Sobol, R.E., Schiffer, C. and Bloomfield, C.D. (1992) Clinical significance of the BCR-ABL fusion gene in adult acute lymphoblastic leukemia: a Cancer and Leukemia Group B Study (8762). Blood, 80, 2983-2990.
-
(1992)
Blood
, vol.80
, pp. 2983-2990
-
-
Westbrook, C.A.1
Hooberman, A.L.2
Spino, C.3
Dodge, R.K.4
Larson, R.A.5
Davey, F.6
Wurster-Hill, D.H.7
Sobol, R.E.8
Schiffer, C.9
Bloomfield, C.D.10
-
46
-
-
0027279628
-
Rearrangement of the MLL gene in acute lymphoblastic and acute myeloid leukemias with 11q23 chromosomal translocations
-
Thirman, M.J., Gill, H.J., Burnett, R.C., Mbangkollo, D., McCabe, N.R., Kobayashi, H., Ziemin-van der Poel, S., Kaneko, Y., Morgan, R., Sandberg, A.A. et al. (1993) Rearrangement of the MLL gene in acute lymphoblastic and acute myeloid leukemias with 11q23 chromosomal translocations. N. Engl. J. Med., 329, 909-914.
-
(1993)
N. Engl. J. Med.
, vol.329
, pp. 909-914
-
-
Thirman, M.J.1
Gill, H.J.2
Burnett, R.C.3
Mbangkollo, D.4
McCabe, N.R.5
Kobayashi, H.6
Ziemin-van der Poel, S.7
Kaneko, Y.8
Morgan, R.9
Sandberg, A.A.10
-
47
-
-
0028364374
-
Fusion of PAX7 to FKHR by the variant t(1;13)(p36;q14) translocation in alveolar rhabdomyosarcoma
-
Davis, R.J., D'Cruz, C.M., Lovell, M.A., Biegel, J.A. and Barr, F.G. (1994) Fusion of PAX7 to FKHR by the variant t(1;13)(p36;q14) translocation in alveolar rhabdomyosarcoma. Cancer Res., 54, 2869-2872.
-
(1994)
Cancer Res.
, vol.54
, pp. 2869-2872
-
-
Davis, R.J.1
D'Cruz, C.M.2
Lovell, M.A.3
Biegel, J.A.4
Barr, F.G.5
-
48
-
-
0028307384
-
A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETS-family transcription factor, ERG
-
Sorensen, P.H., Lessnick, S.L., Lopez-Terrada, D., Liu, X.F., Triche, T.J. and Denny, C.T. (1994) A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETS-family transcription factor, ERG. Nat. Genet., 6, 146-151.
-
(1994)
Nat. Genet.
, vol.6
, pp. 146-151
-
-
Sorensen, P.H.1
Lessnick, S.L.2
Lopez-Terrada, D.3
Liu, X.F.4
Triche, T.J.5
Denny, C.T.6
-
49
-
-
0029004541
-
Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia
-
Golub, T.R., Barker, G.F., Bohlander, S.K., Hiebert, S.W., Ward, D.C., Bray-Ward, P., Morgan, E., Raimondi, S.C., Rowley, J.D. and Gilliland, D.G. (1995) Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia. Proc. Natl. Acad. Sci. USA, 92, 4917-4921.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 4917-4921
-
-
Golub, T.R.1
Barker, G.F.2
Bohlander, S.K.3
Hiebert, S.W.4
Ward, D.C.5
Bray-Ward, P.6
Morgan, E.7
Raimondi, S.C.8
Rowley, J.D.9
Gilliland, D.G.10
-
50
-
-
0030059906
-
In vivo amplification of the PAX3-FKHR and PAX7-FKHR fusion genes in alveolar rhabdomyosarcoma
-
Barr, F.G., Nauta, L.E., Davis, R.J., Schafer, B.W., Nycum, L.M. and Biegel, J.A. (1996) In vivo amplification of the PAX3-FKHR and PAX7-FKHR fusion genes in alveolar rhabdomyosarcoma. Hum. Mol. Genet., 5, 15-21.
-
(1996)
Hum. Mol. Genet.
, vol.5
, pp. 15-21
-
-
Barr, F.G.1
Nauta, L.E.2
Davis, R.J.3
Schafer, B.W.4
Nycum, L.M.5
Biegel, J.A.6
-
51
-
-
0032533497
-
ETV6-NTRK3 gene fusions and trisomy 11 establish a histogenetic link between mesoblastic nephroma and congenital fibrosarcoma
-
Knezevich, S.R., Garnett, M.J., Pysher, T.J., Beckwith, J.B., Grundy, P.E. and Sorensen, P.H. (1998) ETV6-NTRK3 gene fusions and trisomy 11 establish a histogenetic link between mesoblastic nephroma and congenital fibrosarcoma. Cancer Res., 58, 5046-5048.
-
(1998)
Cancer Res.
, vol.58
, pp. 5046-5048
-
-
Knezevich, S.R.1
Garnett, M.J.2
Pysher, T.J.3
Beckwith, J.B.4
Grundy, P.E.5
Sorensen, P.H.6
-
52
-
-
0032190079
-
NUP98-HOXD13 gene fusion in therapy-related acute myelogenous leukemia
-
Raza-Egilmez, S.Z., Jani-Sait, S.N., Grossi, M., Higgins, M.J., Shows, T.B. and Aplan, P.D. (1998) NUP98-HOXD13 gene fusion in therapy-related acute myelogenous leukemia. Cancer Res., 58, 4269-4273.
-
(1998)
Cancer Res.
, vol.58
, pp. 4269-4273
-
-
Raza-Egilmez, S.Z.1
Jani-Sait, S.N.2
Grossi, M.3
Higgins, M.J.4
Shows, T.B.5
Aplan, P.D.6
-
53
-
-
0032898523
-
The role of TEL fusion genes in pediatric leukemias
-
Rubnitz, J.E., Pui, C.H. and Downing, J.R. (1999) The role of TEL fusion genes in pediatric leukemias. Leukemia, 13, 6-13.
-
(1999)
Leukemia
, vol.13
, pp. 6-13
-
-
Rubnitz, J.E.1
Pui, C.H.2
Downing, J.R.3
-
54
-
-
0041353435
-
A novel CLTC-TFE3 gene fusion in pediatric renal adenocarcinoma with t(X;17)(p11.2;q23)
-
Argani, P., Lui, M.Y., Couturier, J., Bouvier, R., Fournet, J.C. and Ladanyi, M. (2003) A novel CLTC-TFE3 gene fusion in pediatric renal adenocarcinoma with t(X;17)(p11.2;q23). Oncogene, 22, 5374-5378.
-
(2003)
Oncogene
, vol.22
, pp. 5374-5378
-
-
Argani, P.1
Lui, M.Y.2
Couturier, J.3
Bouvier, R.4
Fournet, J.C.5
Ladanyi, M.6
-
55
-
-
84891369303
-
Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor ETMR
-
Kleinman, C.L., Gerges, N., Papillon-Cavanagh, S., Sin-Chan, P., Pramatarova, A., Quang, D.A., Adoue, V., Busche, S., Caron, M., Djambazian, H. et al. (2014) Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor ETMR. Nat. Genet., 46, 39-44.
-
(2014)
Nat. Genet.
, vol.46
, pp. 39-44
-
-
Kleinman, C.L.1
Gerges, N.2
Papillon-Cavanagh, S.3
Sin-Chan, P.4
Pramatarova, A.5
Quang, D.A.6
Adoue, V.7
Busche, S.8
Caron, M.9
Djambazian, H.10
-
56
-
-
0021544920
-
Chromosome rearrangements in oncogenesis
-
Nowell, P.C., Emanuel, B.S., Finan, J.B., Erikson, J. and Croce, C.M. (1984) Chromosome rearrangements in oncogenesis. Microbiol. Sci., 1, 223-228.
-
(1984)
Microbiol. Sci.
, vol.1
, pp. 223-228
-
-
Nowell, P.C.1
Emanuel, B.S.2
Finan, J.B.3
Erikson, J.4
Croce, C.M.5
-
57
-
-
78549253454
-
Genotype-phenotype relationship in three cases with overlapping 19p13.12 microdeletions
-
Bonaglia, M.C., Marelli, S., Novara, F., Commodaro, S., Borgatti, R., Minardo, G., Memo, L., Mangold, E., Beri, S., Zucca, C. et al. (2010) Genotype-phenotype relationship in three cases with overlapping 19p13.12 microdeletions. Eur. J. Hum. Genet., 18, 1302-1309.
-
(2010)
Eur. J. Hum. Genet.
, vol.18
, pp. 1302-1309
-
-
Bonaglia, M.C.1
Marelli, S.2
Novara, F.3
Commodaro, S.4
Borgatti, R.5
Minardo, G.6
Memo, L.7
Mangold, E.8
Beri, S.9
Zucca, C.10
-
58
-
-
84890027846
-
A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors
-
Jahchan, N.S., Dudley, J.T., Mazur, P.K., Flores, N., Yang, D., Palmerton, A., Zmoos, A.F., Vaka, D., Tran, K.Q., Zhou, M. et al. (2013) A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors. Cancer Discov., 3, 1364-1377.
-
(2013)
Cancer Discov.
, vol.3
, pp. 1364-1377
-
-
Jahchan, N.S.1
Dudley, J.T.2
Mazur, P.K.3
Flores, N.4
Yang, D.5
Palmerton, A.6
Zmoos, A.F.7
Vaka, D.8
Tran, K.Q.9
Zhou, M.10
-
59
-
-
34248512597
-
Androgen-independent growth and tumorigenesis of prostate cancer cells are enhanced by the presence of PKA-differentiated neuroendocrine cells
-
Deeble, P.D., Cox, M.E., Frierson, H.F. Jr., Sikes, R.A., Palmer, J.B., Davidson, R.J., Casarez, E.V., Amorino, G.P. and Parsons, S.J. (2007) Androgen-independent growth and tumorigenesis of prostate cancer cells are enhanced by the presence of PKA-differentiated neuroendocrine cells. Cancer Res., 67, 3663-3672.
-
(2007)
Cancer Res.
, vol.67
, pp. 3663-3672
-
-
Deeble, P.D.1
Cox, M.E.2
Frierson, H.F.3
Sikes, R.A.4
Palmer, J.B.5
Davidson, R.J.6
Casarez, E.V.7
Amorino, G.P.8
Parsons, S.J.9
-
60
-
-
84877633978
-
p21-Activated kinase 4 promotes prostate cancer progression through CREB
-
Park, M.H., Lee, H.S., Lee, C.S., You, S.T., Kim, D.J., Park, B.H., Kang, M.J., Heo, W.D., Shin, E.Y., Schwartz, M.A. et al. (2013) p21-Activated kinase 4 promotes prostate cancer progression through CREB. Oncogene, 32, 2475-2482.
-
(2013)
Oncogene
, vol.32
, pp. 2475-2482
-
-
Park, M.H.1
Lee, H.S.2
Lee, C.S.3
You, S.T.4
Kim, D.J.5
Park, B.H.6
Kang, M.J.7
Heo, W.D.8
Shin, E.Y.9
Schwartz, M.A.10
-
61
-
-
84901670628
-
Recurrent activating mutation in PRKACA in cortisol-producing adrenal tumors
-
Goh, G., Scholl, U.I., Healy, J.M., Choi, M., Prasad, M.L., Nelson-Williams, C., Kuntsman, J.W., Korah, R., Suttorp, A.C., Dietrich, D. et al. (2014) Recurrent activating mutation in PRKACA in cortisol-producing adrenal tumors. Nat. Genet., 46, 613-617.
-
(2014)
Nat. Genet.
, vol.46
, pp. 613-617
-
-
Goh, G.1
Scholl, U.I.2
Healy, J.M.3
Choi, M.4
Prasad, M.L.5
Nelson-Williams, C.6
Kuntsman, J.W.7
Korah, R.8
Suttorp, A.C.9
Dietrich, D.10
-
62
-
-
84901283149
-
Activating hotspot L205R mutation in PRKACA and adrenal Cushing's syndrome
-
Cao, Y., He, M., Gao, Z., Peng, Y., Li, Y., Li, L., Zhou, W., Li, X., Zhong, X., Lei, Y. et al. (2014) Activating hotspot L205R mutation in PRKACA and adrenal Cushing's syndrome. Science, 344, 913-917.
-
(2014)
Science
, vol.344
, pp. 913-917
-
-
Cao, Y.1
He, M.2
Gao, Z.3
Peng, Y.4
Li, Y.5
Li, L.6
Zhou, W.7
Li, X.8
Zhong, X.9
Lei, Y.10
-
63
-
-
84901217805
-
Recurrent somatic mutations underlie corticotropin-independent Cushing's syndrome
-
Sato, Y., Maekawa, S., Ishii, R., Sanada, M., Morikawa, T., Shiraishi, Y., Yoshida, K., Nagata, Y., Sato-Otsubo, A., Yoshizato, T. et al. (2014) Recurrent somatic mutations underlie corticotropin-independent Cushing's syndrome. Science, 344, 917-920.
-
(2014)
Science
, vol.344
, pp. 917-920
-
-
Sato, Y.1
Maekawa, S.2
Ishii, R.3
Sanada, M.4
Morikawa, T.5
Shiraishi, Y.6
Yoshida, K.7
Nagata, Y.8
Sato-Otsubo, A.9
Yoshizato, T.10
-
64
-
-
58149163292
-
Chromosomal changes in fibrolamellar hepatocellular carcinoma detected by array comparative genomic hybridization
-
Kakar, S., Chen, X., Ho, C., Burgart, L.J., Sahai, V., Dachrut, S., Yabes, A., Jain, D. and Ferrell, L.D. (2009) Chromosomal changes in fibrolamellar hepatocellular carcinoma detected by array comparative genomic hybridization. Mod. Pathol., 22, 134-141.
-
(2009)
Mod. Pathol.
, vol.22
, pp. 134-141
-
-
Kakar, S.1
Chen, X.2
Ho, C.3
Burgart, L.J.4
Sahai, V.5
Dachrut, S.6
Yabes, A.7
Jain, D.8
Ferrell, L.D.9
-
65
-
-
78149440667
-
Frequent and distinct aberrations of DNA methylation patterns in fibrolamellar carcinoma of the liver
-
Trankenschuh, W., Puls, F., Christgen, M., Albat, C., Heim, A., Poczkaj, J., Fleming, P., Kreipe, H. and Lehmann, U. (2010) Frequent and distinct aberrations of DNA methylation patterns in fibrolamellar carcinoma of the liver. PLoS ONE, 5, e13688.
-
(2010)
PLoS ONE
, vol.5
, pp. e13688
-
-
Trankenschuh, W.1
Puls, F.2
Christgen, M.3
Albat, C.4
Heim, A.5
Poczkaj, J.6
Fleming, P.7
Kreipe, H.8
Lehmann, U.9
-
66
-
-
77953128695
-
Mitochondrial mutations in hepatocellular carcinomas and fibrolamellar carcinomas
-
Vivekanandan, P., Daniel, H., Yeh, M.M. and Torbenson, M. (2010) Mitochondrial mutations in hepatocellular carcinomas and fibrolamellar carcinomas. Mod. Pathol., 23, 790-798.
-
(2010)
Mod. Pathol.
, vol.23
, pp. 790-798
-
-
Vivekanandan, P.1
Daniel, H.2
Yeh, M.M.3
Torbenson, M.4
-
67
-
-
82255183150
-
A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer
-
Haiman, C.A., Chen, G.K., Vachon, C.M., Canzian, F., Dunning, A., Millikan, R.C., Wang, X., Ademuyiwa, F., Ahmed, S., Ambrosone, C.B. et al. (2011) A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer. Nat. Genet., 43, 1210-1214.
-
(2011)
Nat. Genet.
, vol.43
, pp. 1210-1214
-
-
Haiman, C.A.1
Chen, G.K.2
Vachon, C.M.3
Canzian, F.4
Dunning, A.5
Millikan, R.C.6
Wang, X.7
Ademuyiwa, F.8
Ahmed, S.9
Ambrosone, C.B.10
-
68
-
-
74949138753
-
Human genome sequencing using unchained base reads on self-assembling DNA nanoarrays
-
Drmanac, R., Sparks, A.B., Callow, M.J., Halpern, A.L., Burns, N.L., Kermani, B.G., Carnevali, P., Nazarenko, I., Nilsen, G.B., Yeung, G. et al. (2010) Human genome sequencing using unchained base reads on self-assembling DNA nanoarrays. Science, 327, 78-81.
-
(2010)
Science
, vol.327
, pp. 78-81
-
-
Drmanac, R.1
Sparks, A.B.2
Callow, M.J.3
Halpern, A.L.4
Burns, N.L.5
Kermani, B.G.6
Carnevali, P.7
Nazarenko, I.8
Nilsen, G.B.9
Yeung, G.10
-
69
-
-
52949114971
-
Hematopoietic stem cell quiescence is maintained by compound contributions of the retinoblastoma gene family
-
Viatour, P., Somervaille, T.C., Venkatasubrahmanyam, S., Kogan, S., McLaughlin, M.E., Weissman, I.L., Butte, A.J., Passegue, E. and Sage, J. (2008) Hematopoietic stem cell quiescence is maintained by compound contributions of the retinoblastoma gene family. Cell Stem Cell, 3, 416-428.
-
(2008)
Cell Stem Cell
, vol.3
, pp. 416-428
-
-
Viatour, P.1
Somervaille, T.C.2
Venkatasubrahmanyam, S.3
Kogan, S.4
McLaughlin, M.E.5
Weissman, I.L.6
Butte, A.J.7
Passegue, E.8
Sage, J.9
|