메뉴 건너뛰기




Volumn 24, Issue 1, 2015, Pages 50-63

Genomic analysis of fibrolamellar hepatocellular carcinoma

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; HEAT SHOCK PROTEIN; HYBRID PROTEIN; PROTEIN VARIANT; TRANSCRIPTOME; CLPTM1L PROTEIN, HUMAN; DNAJB1 PROTEIN, HUMAN; GLIS3 PROTEIN, HUMAN; HEAT SHOCK PROTEIN 40; MEMBRANE PROTEIN; PRKCA PROTEIN, HUMAN; PROTEIN KINASE C ALPHA; TRANSCRIPTION FACTOR; TUMOR PROTEIN;

EID: 84922279148     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddu418     Document Type: Article
Times cited : (64)

References (69)
  • 1
    • 34250020201 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: epidemiology and molecular carcinogenesis
    • El-Serag, H.B. and Rudolph, K.L. (2007) Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology, 132, 2557-2576.
    • (2007) Gastroenterology , vol.132 , pp. 2557-2576
    • El-Serag, H.B.1    Rudolph, K.L.2
  • 2
    • 84873020277 scopus 로고    scopus 로고
    • Pathogenic mechanisms in HBV- and HCV-associated hepatocellular carcinoma
    • Arzumanyan, A., Reis, H.M. and Feitelson, M.A. (2013) Pathogenic mechanisms in HBV- and HCV-associated hepatocellular carcinoma. Nat. Rev. Cancer, 13, 123-135.
    • (2013) Nat. Rev. Cancer , vol.13 , pp. 123-135
    • Arzumanyan, A.1    Reis, H.M.2    Feitelson, M.A.3
  • 4
    • 79951918659 scopus 로고    scopus 로고
    • Fibrolamellar carcinoma: a review with focus on genetics and comparison to other malignant primary liver tumors
    • Ward, S.C. and Waxman, S. (2011) Fibrolamellar carcinoma: a review with focus on genetics and comparison to other malignant primary liver tumors. Semin. Liver Dis., 31, 61-70.
    • (2011) Semin. Liver Dis. , vol.31 , pp. 61-70
    • Ward, S.C.1    Waxman, S.2
  • 5
    • 1542724808 scopus 로고    scopus 로고
    • Is fibrolamellar carcinoma different from hepatocellular carcinoma? A US population-based study
    • El-Serag, H.B. and Davila, J.A. (2004) Is fibrolamellar carcinoma different from hepatocellular carcinoma? A US population-based study. Hepatology, 39, 798-803.
    • (2004) Hepatology , vol.39 , pp. 798-803
    • El-Serag, H.B.1    Davila, J.A.2
  • 6
    • 27144486411 scopus 로고    scopus 로고
    • Clinicopathologic features and survival in fibrolamellar carcinoma: comparison with conventional hepatocellular carcinoma with and without cirrhosis
    • Kakar, S., Burgart, L.J., Batts, K.P., Garcia, J., Jain, D. and Ferrell, L.D. (2005) Clinicopathologic features and survival in fibrolamellar carcinoma: comparison with conventional hepatocellular carcinoma with and without cirrhosis. Mod. Pathol., 18, 1417-1423.
    • (2005) Mod. Pathol. , vol.18 , pp. 1417-1423
    • Kakar, S.1    Burgart, L.J.2    Batts, K.P.3    Garcia, J.4    Jain, D.5    Ferrell, L.D.6
  • 7
    • 0018829934 scopus 로고
    • Fibrolamellar carcinoma of the liver: a tumor of adolescents and young adults with distinctive clinico-pathologic features
    • Craig, J.R., Peters, R.L., Edmondson, H.A. and Omata, M. (1980) Fibrolamellar carcinoma of the liver: a tumor of adolescents and young adults with distinctive clinico-pathologic features. Cancer, 46, 372-379.
    • (1980) Cancer , vol.46 , pp. 372-379
    • Craig, J.R.1    Peters, R.L.2    Edmondson, H.A.3    Omata, M.4
  • 8
    • 70350492933 scopus 로고    scopus 로고
    • Fibrolamellar hepatocellular carcinoma
    • quiz 2625
    • Liu, S., Chan, K.W., Wang, B. and Qiao, L. (2009) Fibrolamellar hepatocellular carcinoma. Am. J. Gastroenterol., 104, 2617-2624. quiz 2625.
    • (2009) Am. J. Gastroenterol. , vol.104 , pp. 2617-2624
    • Liu, S.1    Chan, K.W.2    Wang, B.3    Qiao, L.4
  • 10
    • 77956295659 scopus 로고    scopus 로고
    • Fibrolamellar carcinoma of the liver exhibits immunohistochemical evidence of both hepatocyte and bile duct differentiation
    • Ward, S.C., Huang, J., Tickoo, S.K., Thung, S.N., Ladanyi, M. and Klimstra, D.S. (2010) Fibrolamellar carcinoma of the liver exhibits immunohistochemical evidence of both hepatocyte and bile duct differentiation. Mod. Pathol., 23, 1180-1190.
    • (2010) Mod. Pathol. , vol.23 , pp. 1180-1190
    • Ward, S.C.1    Huang, J.2    Tickoo, S.K.3    Thung, S.N.4    Ladanyi, M.5    Klimstra, D.S.6
  • 14
    • 33947149044 scopus 로고    scopus 로고
    • Fibrolamellar carcinomas show overexpression of genes in the RAS, MAPK, PIK3, and xenobiotic degradation pathways
    • Kannangai, R., Vivekanandan, P., Martinez-Murillo, F., Choti, M. and Torbenson, M. (2007) Fibrolamellar carcinomas show overexpression of genes in the RAS, MAPK, PIK3, and xenobiotic degradation pathways. Hum. Pathol., 38, 639-644.
    • (2007) Hum. Pathol. , vol.38 , pp. 639-644
    • Kannangai, R.1    Vivekanandan, P.2    Martinez-Murillo, F.3    Choti, M.4    Torbenson, M.5
  • 15
    • 33645116622 scopus 로고    scopus 로고
    • Epidermal growth factor receptor expression and gene copy number in fibrolamellar hepatocellular carcinoma
    • Buckley, A.F., Burgart, L.J. and Kakar, S. (2006) Epidermal growth factor receptor expression and gene copy number in fibrolamellar hepatocellular carcinoma. Hum. Pathol., 37, 410-414.
    • (2006) Hum. Pathol. , vol.37 , pp. 410-414
    • Buckley, A.F.1    Burgart, L.J.2    Kakar, S.3
  • 16
    • 63349098247 scopus 로고    scopus 로고
    • Unique phenotype of hepatocellular cancers with exon-3 mutations in beta-catenin gene
    • Cieply, B., Zeng, G., Proverbs-Singh, T., Geller, D.A. and Monga, S.P. (2009) Unique phenotype of hepatocellular cancers with exon-3 mutations in beta-catenin gene. Hepatology, 49, 821-831.
    • (2009) Hepatology , vol.49 , pp. 821-831
    • Cieply, B.1    Zeng, G.2    Proverbs-Singh, T.3    Geller, D.A.4    Monga, S.P.5
  • 17
    • 0030762644 scopus 로고    scopus 로고
    • Lamellar fibrosis in the fibrolamellar variant of hepatocellular carcinoma: a role for transforming growth factor beta
    • Orsatti, G., Hytiroglou, P., Thung, S.N., Ishak, K.G. and Paronetto, F. (1997) Lamellar fibrosis in the fibrolamellar variant of hepatocellular carcinoma: a role for transforming growth factor beta. Liver, 17, 152-156.
    • (1997) Liver , vol.17 , pp. 152-156
    • Orsatti, G.1    Hytiroglou, P.2    Thung, S.N.3    Ishak, K.G.4    Paronetto, F.5
  • 18
    • 77953423408 scopus 로고    scopus 로고
    • Constitutive activation of nuclear factor-kappa B (NF-kB) signaling pathway in fibrolamellar hepatocellular carcinoma
    • Li, W., Tan, D., Zenali, M.J. and Brown, R.E. (2010) Constitutive activation of nuclear factor-kappa B (NF-kB) signaling pathway in fibrolamellar hepatocellular carcinoma. Int. J. Clin. Exp. Pathol., 3, 238-243.
    • (2010) Int. J. Clin. Exp. Pathol. , vol.3 , pp. 238-243
    • Li, W.1    Tan, D.2    Zenali, M.J.3    Brown, R.E.4
  • 19
    • 84856090070 scopus 로고    scopus 로고
    • Loss of the orphan nuclear receptor SHP is more pronounced in fibrolamellar carcinoma than in typical hepatocellular carcinoma
    • Wilczek, E., Szparecki, G., Lukasik, D., Koperski, L., Winiarska, M., Wilczynski, G.M., Wasiutynski, A. and Gornicka, B. (2012) Loss of the orphan nuclear receptor SHP is more pronounced in fibrolamellar carcinoma than in typical hepatocellular carcinoma. PLoS ONE, 7, e30944.
    • (2012) PLoS ONE , vol.7 , pp. e30944
    • Wilczek, E.1    Szparecki, G.2    Lukasik, D.3    Koperski, L.4    Winiarska, M.5    Wilczynski, G.M.6    Wasiutynski, A.7    Gornicka, B.8
  • 20
    • 84899838345 scopus 로고    scopus 로고
    • Prognosis of patients with fibrolamellar hepatocellular carcinoma versus conventional hepatocellular carcinoma: a systematic review and meta-analysis
    • Njei, B., Konjeti, V.R. and Ditah, I. (2014) Prognosis of patients with fibrolamellar hepatocellular carcinoma versus conventional hepatocellular carcinoma: a systematic review and meta-analysis. Gastrointest. Cancer Res., 7, 49-54.
    • (2014) Gastrointest. Cancer Res. , vol.7 , pp. 49-54
    • Njei, B.1    Konjeti, V.R.2    Ditah, I.3
  • 21
    • 0028912086 scopus 로고
    • Fibrolamellar hepatocellular carcinoma: stage at presentation and results of aggressive surgical management
    • Stevens, W.R., Johnson, C.D., Stephens, D.H. and Nagorney, D.M. (1995) Fibrolamellar hepatocellular carcinoma: stage at presentation and results of aggressive surgical management. AJR Am. J. Roentgenol., 164, 1153-1158.
    • (1995) AJR Am. J. Roentgenol. , vol.164 , pp. 1153-1158
    • Stevens, W.R.1    Johnson, C.D.2    Stephens, D.H.3    Nagorney, D.M.4
  • 24
    • 84868314554 scopus 로고    scopus 로고
    • Fibrolamellar variant of hepatocellular carcinoma
    • Chun, Y.S. and Zimmitti, G. (2013) Fibrolamellar variant of hepatocellular carcinoma. Recent Results Cancer Res., 190, 101-110.
    • (2013) Recent Results Cancer Res. , vol.190 , pp. 101-110
    • Chun, Y.S.1    Zimmitti, G.2
  • 26
    • 59049098400 scopus 로고    scopus 로고
    • Anterior gradient-2 is overexpressed by fibrolamellar carcinomas
    • Vivekanandan, P., Micchelli, S.T. and Torbenson, M. (2009) Anterior gradient-2 is overexpressed by fibrolamellar carcinomas. Hum. Pathol., 40, 293-299.
    • (2009) Hum. Pathol. , vol.40 , pp. 293-299
    • Vivekanandan, P.1    Micchelli, S.T.2    Torbenson, M.3
  • 32
    • 84862976633 scopus 로고    scopus 로고
    • Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators
    • Fujimoto, A., Totoki, Y., Abe, T., Boroevich, K.A., Hosoda, F., Nguyen, H.H., Aoki, M., Hosono, N., Kubo, M., Miya, F. et al. (2012) Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators. Nat. Genet., 44, 760-764.
    • (2012) Nat. Genet. , vol.44 , pp. 760-764
    • Fujimoto, A.1    Totoki, Y.2    Abe, T.3    Boroevich, K.A.4    Hosoda, F.5    Nguyen, H.H.6    Aoki, M.7    Hosono, N.8    Kubo, M.9    Miya, F.10
  • 35
    • 0034601378 scopus 로고    scopus 로고
    • Distinct chromosomal abnormality pattern in primary liver cancer of non-B, non-C patients
    • Marchio, A., Pineau, P., Meddeb, M., Terris, B., Tiollais, P., Bernheim, A. and Dejean, A. (2000) Distinct chromosomal abnormality pattern in primary liver cancer of non-B, non-C patients. Oncogene, 19, 3733-3738.
    • (2000) Oncogene , vol.19 , pp. 3733-3738
    • Marchio, A.1    Pineau, P.2    Meddeb, M.3    Terris, B.4    Tiollais, P.5    Bernheim, A.6    Dejean, A.7
  • 36
    • 0034525791 scopus 로고    scopus 로고
    • Cytogenetic aberrations in primary and recurrent fibrolamellar hepatocellular carcinoma detected by comparative genomic hybridization
    • Wilkens, L., Bredt, M., Flemming, P., Kubicka, S., Klempnauer, J. and Kreipe, H. (2000) Cytogenetic aberrations in primary and recurrent fibrolamellar hepatocellular carcinoma detected by comparative genomic hybridization. Am. J. Clin. Pathol., 114, 867-874.
    • (2000) Am. J. Clin. Pathol. , vol.114 , pp. 867-874
    • Wilkens, L.1    Bredt, M.2    Flemming, P.3    Kubicka, S.4    Klempnauer, J.5    Kreipe, H.6
  • 37
    • 0026529566 scopus 로고
    • Intracellular localization and partial amino acid sequence of a stress-inducible 40-kDa protein in HeLa cells
    • Hattori, H., Liu, Y.C., Tohnai, I., Ueda, M., Kaneda, T., Kobayashi, T., Tanabe, K. and Ohtsuka, K. (1992) Intracellular localization and partial amino acid sequence of a stress-inducible 40-kDa protein in HeLa cells. Cell Struct. Funct., 17, 77-86.
    • (1992) Cell Struct. Funct. , vol.17 , pp. 77-86
    • Hattori, H.1    Liu, Y.C.2    Tohnai, I.3    Ueda, M.4    Kaneda, T.5    Kobayashi, T.6    Tanabe, K.7    Ohtsuka, K.8
  • 38
    • 31144458770 scopus 로고    scopus 로고
    • Oscillations of cyclic AMP in hormone-stimulated insulin-secreting beta-cells
    • Dyachok, O., Isakov, Y., Sagetorp, J. and Tengholm, A. (2006) Oscillations of cyclic AMP in hormone-stimulated insulin-secreting beta-cells. Nature, 439, 349-352.
    • (2006) Nature , vol.439 , pp. 349-352
    • Dyachok, O.1    Isakov, Y.2    Sagetorp, J.3    Tengholm, A.4
  • 42
    • 33947581390 scopus 로고    scopus 로고
    • The impact of translocations and gene fusions on cancer causation
    • Mitelman, F., Johansson, B. and Mertens, F. (2007) The impact of translocations and gene fusions on cancer causation. Nat. Rev. Cancer, 7, 233-245.
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 233-245
    • Mitelman, F.1    Johansson, B.2    Mertens, F.3
  • 47
    • 0028364374 scopus 로고
    • Fusion of PAX7 to FKHR by the variant t(1;13)(p36;q14) translocation in alveolar rhabdomyosarcoma
    • Davis, R.J., D'Cruz, C.M., Lovell, M.A., Biegel, J.A. and Barr, F.G. (1994) Fusion of PAX7 to FKHR by the variant t(1;13)(p36;q14) translocation in alveolar rhabdomyosarcoma. Cancer Res., 54, 2869-2872.
    • (1994) Cancer Res. , vol.54 , pp. 2869-2872
    • Davis, R.J.1    D'Cruz, C.M.2    Lovell, M.A.3    Biegel, J.A.4    Barr, F.G.5
  • 48
    • 0028307384 scopus 로고
    • A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETS-family transcription factor, ERG
    • Sorensen, P.H., Lessnick, S.L., Lopez-Terrada, D., Liu, X.F., Triche, T.J. and Denny, C.T. (1994) A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETS-family transcription factor, ERG. Nat. Genet., 6, 146-151.
    • (1994) Nat. Genet. , vol.6 , pp. 146-151
    • Sorensen, P.H.1    Lessnick, S.L.2    Lopez-Terrada, D.3    Liu, X.F.4    Triche, T.J.5    Denny, C.T.6
  • 50
    • 0030059906 scopus 로고    scopus 로고
    • In vivo amplification of the PAX3-FKHR and PAX7-FKHR fusion genes in alveolar rhabdomyosarcoma
    • Barr, F.G., Nauta, L.E., Davis, R.J., Schafer, B.W., Nycum, L.M. and Biegel, J.A. (1996) In vivo amplification of the PAX3-FKHR and PAX7-FKHR fusion genes in alveolar rhabdomyosarcoma. Hum. Mol. Genet., 5, 15-21.
    • (1996) Hum. Mol. Genet. , vol.5 , pp. 15-21
    • Barr, F.G.1    Nauta, L.E.2    Davis, R.J.3    Schafer, B.W.4    Nycum, L.M.5    Biegel, J.A.6
  • 51
    • 0032533497 scopus 로고    scopus 로고
    • ETV6-NTRK3 gene fusions and trisomy 11 establish a histogenetic link between mesoblastic nephroma and congenital fibrosarcoma
    • Knezevich, S.R., Garnett, M.J., Pysher, T.J., Beckwith, J.B., Grundy, P.E. and Sorensen, P.H. (1998) ETV6-NTRK3 gene fusions and trisomy 11 establish a histogenetic link between mesoblastic nephroma and congenital fibrosarcoma. Cancer Res., 58, 5046-5048.
    • (1998) Cancer Res. , vol.58 , pp. 5046-5048
    • Knezevich, S.R.1    Garnett, M.J.2    Pysher, T.J.3    Beckwith, J.B.4    Grundy, P.E.5    Sorensen, P.H.6
  • 53
    • 0032898523 scopus 로고    scopus 로고
    • The role of TEL fusion genes in pediatric leukemias
    • Rubnitz, J.E., Pui, C.H. and Downing, J.R. (1999) The role of TEL fusion genes in pediatric leukemias. Leukemia, 13, 6-13.
    • (1999) Leukemia , vol.13 , pp. 6-13
    • Rubnitz, J.E.1    Pui, C.H.2    Downing, J.R.3
  • 54
    • 0041353435 scopus 로고    scopus 로고
    • A novel CLTC-TFE3 gene fusion in pediatric renal adenocarcinoma with t(X;17)(p11.2;q23)
    • Argani, P., Lui, M.Y., Couturier, J., Bouvier, R., Fournet, J.C. and Ladanyi, M. (2003) A novel CLTC-TFE3 gene fusion in pediatric renal adenocarcinoma with t(X;17)(p11.2;q23). Oncogene, 22, 5374-5378.
    • (2003) Oncogene , vol.22 , pp. 5374-5378
    • Argani, P.1    Lui, M.Y.2    Couturier, J.3    Bouvier, R.4    Fournet, J.C.5    Ladanyi, M.6
  • 58
    • 84890027846 scopus 로고    scopus 로고
    • A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors
    • Jahchan, N.S., Dudley, J.T., Mazur, P.K., Flores, N., Yang, D., Palmerton, A., Zmoos, A.F., Vaka, D., Tran, K.Q., Zhou, M. et al. (2013) A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors. Cancer Discov., 3, 1364-1377.
    • (2013) Cancer Discov. , vol.3 , pp. 1364-1377
    • Jahchan, N.S.1    Dudley, J.T.2    Mazur, P.K.3    Flores, N.4    Yang, D.5    Palmerton, A.6    Zmoos, A.F.7    Vaka, D.8    Tran, K.Q.9    Zhou, M.10
  • 59
    • 34248512597 scopus 로고    scopus 로고
    • Androgen-independent growth and tumorigenesis of prostate cancer cells are enhanced by the presence of PKA-differentiated neuroendocrine cells
    • Deeble, P.D., Cox, M.E., Frierson, H.F. Jr., Sikes, R.A., Palmer, J.B., Davidson, R.J., Casarez, E.V., Amorino, G.P. and Parsons, S.J. (2007) Androgen-independent growth and tumorigenesis of prostate cancer cells are enhanced by the presence of PKA-differentiated neuroendocrine cells. Cancer Res., 67, 3663-3672.
    • (2007) Cancer Res. , vol.67 , pp. 3663-3672
    • Deeble, P.D.1    Cox, M.E.2    Frierson, H.F.3    Sikes, R.A.4    Palmer, J.B.5    Davidson, R.J.6    Casarez, E.V.7    Amorino, G.P.8    Parsons, S.J.9
  • 62
    • 84901283149 scopus 로고    scopus 로고
    • Activating hotspot L205R mutation in PRKACA and adrenal Cushing's syndrome
    • Cao, Y., He, M., Gao, Z., Peng, Y., Li, Y., Li, L., Zhou, W., Li, X., Zhong, X., Lei, Y. et al. (2014) Activating hotspot L205R mutation in PRKACA and adrenal Cushing's syndrome. Science, 344, 913-917.
    • (2014) Science , vol.344 , pp. 913-917
    • Cao, Y.1    He, M.2    Gao, Z.3    Peng, Y.4    Li, Y.5    Li, L.6    Zhou, W.7    Li, X.8    Zhong, X.9    Lei, Y.10
  • 64
    • 58149163292 scopus 로고    scopus 로고
    • Chromosomal changes in fibrolamellar hepatocellular carcinoma detected by array comparative genomic hybridization
    • Kakar, S., Chen, X., Ho, C., Burgart, L.J., Sahai, V., Dachrut, S., Yabes, A., Jain, D. and Ferrell, L.D. (2009) Chromosomal changes in fibrolamellar hepatocellular carcinoma detected by array comparative genomic hybridization. Mod. Pathol., 22, 134-141.
    • (2009) Mod. Pathol. , vol.22 , pp. 134-141
    • Kakar, S.1    Chen, X.2    Ho, C.3    Burgart, L.J.4    Sahai, V.5    Dachrut, S.6    Yabes, A.7    Jain, D.8    Ferrell, L.D.9
  • 66
    • 77953128695 scopus 로고    scopus 로고
    • Mitochondrial mutations in hepatocellular carcinomas and fibrolamellar carcinomas
    • Vivekanandan, P., Daniel, H., Yeh, M.M. and Torbenson, M. (2010) Mitochondrial mutations in hepatocellular carcinomas and fibrolamellar carcinomas. Mod. Pathol., 23, 790-798.
    • (2010) Mod. Pathol. , vol.23 , pp. 790-798
    • Vivekanandan, P.1    Daniel, H.2    Yeh, M.M.3    Torbenson, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.