Natural lignans from Arctium lappa modulate P-glycoprotein efflux function in multidrug resistant cancer cells

Phytomedicine

Volumn 22, Issue 2, 2015, Pages 301-307

  Su, Shan ^a   Cheng, Xinlai ^a   Wink, Michael ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Arctium lappa; Cancer cells; Lignans; Multidrug resistance; P glycoprotein

Indexed keywords

ABC TRANSPORTER; ANTINEOPLASTIC AGENT; ARCTIGENIN; ARCTIIN; DIGITONIN; DOXORUBICIN; LAPPAOL A; LAPPAOL C; LAPPAOL F; LIGNAN DERIVATIVE; MATAIRESINOL; MULTIDRUG RESISTANCE PROTEIN; RHODAMINE 123; UNCLASSIFIED DRUG; BENZOFURAN DERIVATIVE; FURAN DERIVATIVE; GAMMA BUTYROLACTONE; GLUCOSIDE; LIGNAN;

ARCTIUM LAPPA; ARTICLE; CACO 2 CELL LINE; CANCER CELL; CANCER RESISTANCE; CELL MEMBRANE PERMEABILITY; CYTOTOXICITY; CYTOTOXICITY ASSAY; DRUG MECHANISM; DRUG POTENCY; DRUG POTENTIATION; HUMAN; HUMAN CELL; IC50; MULTIDRUG RESISTANCE; PLANT SEED; PRIORITY JOURNAL; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; ARCTIUM; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; DRUG RESISTANCE; TUMOR CELL LINE;

ARCTIUM LAPPA;

4-BUTYROLACTONE; ANTINEOPLASTIC AGENTS; ARCTIUM; BENZOFURANS; CACO-2 CELLS; CELL LINE, TUMOR; DOXORUBICIN; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; DRUG SYNERGISM; FURANS; GLUCOSIDES; HUMANS; LIGNANS; MOLECULAR STRUCTURE; P-GLYCOPROTEINS; RHODAMINE 123; SEEDS;

EID: 84922260782     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2014.12.009     Document Type: Article

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