The effect of peroxynitrite decomposition catalyst MnTBAP on aldehyde dehydrogenase-2 nitration by organic nitrates: Role in nitrate tolerance

Pharmacological Research

Volumn 89, Issue , 2014, Pages 29-35

  Mollace, Vincenzo ^a,b   Muscoli, Carolina ^a,b   Dagostino, Concetta ^a   Giancotti, Luigino Antonio ^a   Gliozzi, Micaela ^a,b   Sacco, Iolanda ^c   Visalli, Valeria ^c   Gratteri, Santo ^a   Palma, Ernesto ^a   Malara, Natalia ^a   Musolino, Vincenzo ^a   Carresi, Cristina ^a   Muscoli, Saverio ^d   Vitale, Cristiana ^b   Salvemini, Daniela ^e   Romeo, Francesco ^d  

^a UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

^b IRCCS SAN RAFFAELE PISANA   (Italy)

^c Dipartimento Provinciale di Crotone Coordinamento attività SIN Servizio Tematico Aerea   (Italy)

^d TOR VERGATA UNIVERSITY HOSPITAL   (Italy)

^e SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Nitrate tolerance Oxidative stress ALDH 2 nitration Peroxynitrite decomposition catalyst

Indexed keywords

ALDEHYDE DEHYDROGENASE ISOENZYME 2; GLYCERYL TRINITRATE; ISOSORBIDE 5 NITRATE; MANGANESE TETRAKIS (4 BENZOIC ACID) PORPHYRIN; NITRIC OXIDE; PEROXYNITRITE; PORPHYRIN DERIVATIVE; UNCLASSIFIED DRUG; 3-NITROTYROSINE; ALDEHYDE DEHYDROGENASE; CYCLIC GMP; ISOSORBIDE DINITRATE; ISOSORBIDE MONONITRATE; MANGANESE(III)-TETRAKIS(4-BENZOIC ACID)PORPHYRIN; METALLOPORPHYRIN; NITRIC ACID DERIVATIVE; NITRITE; THROMBIN; TYROSINE; VASODILATOR AGENT;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOTRANSFORMATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DECOMPOSITION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; NITRATE TOLERANCE; NITRATION; NONHUMAN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PHYSICAL TOLERANCE; RAT; SMOOTH MUSCLE FIBER; THROMBOCYTE AGGREGATION; VASODILATATION; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; AORTA; BIOSYNTHESIS; CHEMICALLY INDUCED; DRUG EFFECTS; DRUG TOLERANCE; HYPOTENSION; METABOLISM; THROMBOCYTE; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE;

ALDEHYDE DEHYDROGENASE; ANIMALS; AORTA; BLOOD PLATELETS; CYCLIC GMP; DRUG TOLERANCE; ENDOTHELIUM, VASCULAR; HUMANS; HYPOTENSION; ISOSORBIDE DINITRATE; MALE; METALLOPORPHYRINS; MUSCLE, SMOOTH, VASCULAR; NITRATES; NITRIC OXIDE; NITRITES; NITROGLYCERIN; PLATELET AGGREGATION; RATS; THROMBIN; TYROSINE; VASODILATOR AGENTS;

EID: 84922235025     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2014.07.007     Document Type: Article

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