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Volumn 136, Issue 6, 2015, Pages E488-E495

Multiple mucin depleted foci, high proliferation and low apoptotic response in the onset of colon carcinogenesis of the PIRC rat, mutated in Apc

Author keywords

Apc; Colon carcinogenesis; Mucin depleted foci; PIRC rat

Indexed keywords

APC PROTEIN; BETA CATENIN; CYCLINE; MANGANESE SUPEROXIDE DISMUTASE; MUCIN; PROTEIN P21; REACTIVE OXYGEN METABOLITE; SULINDAC; BIRC5 PROTEIN, RAT; CYCLIN DEPENDENT KINASE INHIBITOR 1A; MICROTUBULE ASSOCIATED PROTEIN;

EID: 84922186890     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.29232     Document Type: Article
Times cited : (23)

References (37)
  • 1
    • 33744973579 scopus 로고    scopus 로고
    • Cancer genetics: Colorectal cancer as a model
    • Bodmer WF. Cancer genetics: colorectal cancer as a model. J Hum Genet 2006;51:391-6.
    • (2006) J Hum Genet , vol.51 , pp. 391-396
    • Bodmer, W.F.1
  • 2
    • 84877109867 scopus 로고    scopus 로고
    • More than two decades of Apc modeling in rodents
    • Zeineldin M, Neufeld KL. More than two decades of Apc modeling in rodents. Biochim Biophys Acta 2013;1836:80-9.
    • (2013) Biochim Biophys Acta , vol.1836 , pp. 80-89
    • Zeineldin, M.1    Neufeld, K.L.2
  • 3
    • 84875244212 scopus 로고    scopus 로고
    • Pathology of rodent models of intestinal cancer: Progress report and recommendations
    • Washington MK, Powell AE, Sullivan R, et al. Pathology of rodent models of intestinal cancer: progress report and recommendations. Gastroenterology 2013;144:705-17.
    • (2013) Gastroenterology , vol.144 , pp. 705-717
    • Washington, M.K.1    Powell, A.E.2    Sullivan, R.3
  • 5
    • 34247231997 scopus 로고    scopus 로고
    • A target-selected Apc-mutant rat kindred enhances the modeling of familial human colon cancer
    • Amos-Landgraf JM, Kwong LN, Kendziorski CM, et al. A target-selected Apc-mutant rat kindred enhances the modeling of familial human colon cancer. Proc Natl Acad Sci USA 2007;104:4036-41.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 4036-4041
    • Amos-Landgraf, J.M.1    Kwong, L.N.2    Kendziorski, C.M.3
  • 6
    • 0038181338 scopus 로고    scopus 로고
    • Identification of mucin-depleted foci in the unsectioned colon of azoxymethane-treated rats: Correlation with carcinogenesis
    • Caderni G, Femia AP, Giannini A, et al. Identification of mucin-depleted foci in the unsectioned colon of azoxymethane-treated rats: correlation with carcinogenesis. Cancer Res 2003;63:2388-92.
    • (2003) Cancer Res , vol.63 , pp. 2388-2392
    • Caderni, G.1    Femia, A.P.2    Giannini, A.3
  • 7
    • 62349118260 scopus 로고    scopus 로고
    • Identification of mucin depleted foci in the human colon
    • Femia AP, Giannini A, Fazi M, et al. Identification of mucin depleted foci in the human colon. Cancer Prev Res (Phila) 2008;1:562-7.
    • (2008) Cancer Prev Res (Phila) , vol.1 , pp. 562-567
    • Femia, A.P.1    Giannini, A.2    Fazi, M.3
  • 8
    • 33846680079 scopus 로고    scopus 로고
    • Frequent mutation of Apc gene in rat colon tumours and mucin-depleted foci, preneoplastic lesions in experimental colon carcinogenesis
    • Femia AP, Dolara P, Giannini A, et al. Frequent mutation of Apc gene in rat colon tumours and mucin-depleted foci, preneoplastic lesions in experimental colon carcinogenesis. Cancer Res 2007;67:445-9.
    • (2007) Cancer Res , vol.67 , pp. 445-449
    • Femia, A.P.1    Dolara, P.2    Giannini, A.3
  • 9
    • 20444447560 scopus 로고    scopus 로고
    • Mucin-depleted foci have beta-catenin gene mutations, altered expression of its protein, and are dose- and time-dependent in the colon of 1,2-dimethylhydrazine-treated rats
    • Femia AP, Bendinelli B, Giannini A, et al. Mucin-depleted foci have beta-catenin gene mutations, altered expression of its protein, and are dose- and time-dependent in the colon of 1,2-dimethylhydrazine-treated rats. Int J Cancer 2005;116:9-15.
    • (2005) Int J Cancer , vol.116 , pp. 9-15
    • Femia, A.P.1    Bendinelli, B.2    Giannini, A.3
  • 10
    • 0028904461 scopus 로고
    • Chemoprevention of colon carcinogenesis by sulindac, a nonsteroidal anti-inflammatory agent
    • Rao CV, Rivenson A, Simi B, et al. Chemoprevention of colon carcinogenesis by sulindac, a nonsteroidal anti-inflammatory agent. Cancer Res 1995;55:1464-72.
    • (1995) Cancer Res , vol.55 , pp. 1464-1472
    • Rao, C.V.1    Rivenson, A.2    Simi, B.3
  • 11
    • 42549165647 scopus 로고    scopus 로고
    • Guidelines for the clinical management of familial adenomatous polyposis (FAP)
    • Vasen HF, Möslein G, Alonso A, et al. Guidelines for the clinical management of familial adenomatous polyposis (FAP). Gut 2008;57:704-13.
    • (2008) Gut , vol.57 , pp. 704-713
    • Vasen, H.F.1    Möslein, G.2    Alonso, A.3
  • 12
    • 0037212476 scopus 로고    scopus 로고
    • Changes in apoptosis during the development of colorectal cancer: A systematic review of the literature
    • Koornstra JJ, de Jong S, Hollema H, et al. Changes in apoptosis during the development of colorectal cancer: a systematic review of the literature. Crit Rev Oncol Hematol 2003;45:37-53.
    • (2003) Crit Rev Oncol Hematol , vol.45 , pp. 37-53
    • Koornstra, J.J.1    De Jong, S.2    Hollema, H.3
  • 13
    • 54749148733 scopus 로고    scopus 로고
    • One-hit effects in cancer: Altered proteome of morphologically normal colon crypts in familial adenomatous polyposis
    • Yeung AT, Patel BB, Li XM, et al. One-hit effects in cancer: altered proteome of morphologically normal colon crypts in familial adenomatous polyposis. Cancer Res 2008;68:7579-86.
    • (2008) Cancer Res , vol.68 , pp. 7579-7586
    • Yeung, A.T.1    Patel, B.B.2    Li, X.M.3
  • 14
    • 0016614267 scopus 로고
    • Proliferative patterns in colonic mucosa in familial polyposis
    • Deschner EE, Lipkin M. Proliferative patterns in colonic mucosa in familial polyposis. Cancer 1975;35:413-18.
    • (1975) Cancer , vol.35 , pp. 413-418
    • Deschner, E.E.1    Lipkin, M.2
  • 15
    • 0041589514 scopus 로고    scopus 로고
    • Regulation of caspase expression and apoptosis by adenomatous polyposis coli
    • Chen T, Yang I, Irby R, et al. Regulation of caspase expression and apoptosis by adenomatous polyposis coli. Cancer Res 2003;63:4368-74.
    • (2003) Cancer Res , vol.63 , pp. 4368-4374
    • Chen, T.1    Yang, I.2    Irby, R.3
  • 16
    • 33847248949 scopus 로고    scopus 로고
    • Defective acute apoptotic response to genotoxic carcinogen in small intestine of APC(Min/+) mice is restored by sulindac
    • Hu Y, Le Leu RK, Young GP. Defective acute apoptotic response to genotoxic carcinogen in small intestine of APC(Min/+) mice is restored by sulindac. Cancer Lett 2007;248:234-44.
    • (2007) Cancer Lett , vol.248 , pp. 234-244
    • Hu, Y.1    Le Leu, R.K.2    Young, G.P.3
  • 17
    • 84861561353 scopus 로고    scopus 로고
    • Sustained proliferation and resistance to apoptosis after a cytotoxic insult are early alterations in rat colon carcinogenesis
    • Femia AP, Salvianti F, Luceri C, et al. Sustained proliferation and resistance to apoptosis after a cytotoxic insult are early alterations in rat colon carcinogenesis. Int J Cancer 2012;131:529-36.
    • (2012) Int J Cancer , vol.131 , pp. 529-536
    • Femia, A.P.1    Salvianti, F.2    Luceri, C.3
  • 18
    • 77951946768 scopus 로고    scopus 로고
    • Gene expression profile and genomic alterations in colonic tumours induced by 1,2-dimethylhydrazine (DMH) in rats
    • Femia AP, Luceri C, Toti S, et al. Gene expression profile and genomic alterations in colonic tumours induced by 1,2-dimethylhydrazine (DMH) in rats. BMC Cancer 2010;10:194.
    • (2010) BMC Cancer , vol.10 , pp. 194
    • Femia, A.P.1    Luceri, C.2    Toti, S.3
  • 19
    • 55649086170 scopus 로고    scopus 로고
    • Evaluation of a novel colorimetric assay for free oxygen radicals as marker of oxidative stress
    • Garelnabi MO, Brown WV, Le NA. Evaluation of a novel colorimetric assay for free oxygen radicals as marker of oxidative stress. Clin Biochem 2008;41:1250-4.
    • (2008) Clin Biochem , vol.41 , pp. 1250-1254
    • Garelnabi, M.O.1    Brown, W.V.2    Le, N.A.3
  • 20
    • 0030586361 scopus 로고    scopus 로고
    • The ferric reducing ability of plasma (FRAP) as a measure of "antioxidant power": The FRAP assay
    • Benzie IF, Strain JJ. The ferric reducing ability of plasma (FRAP) as a measure of "antioxidant power": the FRAP assay. Anal Biochem 1996;239:70-6.
    • (1996) Anal Biochem , vol.239 , pp. 70-76
    • Benzie, I.F.1    Strain, J.J.2
  • 21
    • 58949099525 scopus 로고    scopus 로고
    • Reactive oxidant species and oxidation of protein and haemoglobin as biomarkers of susceptibility to stress caused by chloramphenicol
    • Correa-Salde V, Albesa I. Reactive oxidant species and oxidation of protein and haemoglobin as biomarkers of susceptibility to stress caused by chloramphenicol. Biomed Pharmacother 2009;63:100-104.
    • (2009) Biomed Pharmacother , vol.63 , pp. 100-104
    • Correa-Salde, V.1    Albesa, I.2
  • 22
    • 10044221016 scopus 로고    scopus 로고
    • Colorectal cancers in a new mouse model of familial adenomatous polyposis: Influence of genetic and environmental modifiers
    • Colnot S, Niwa-Kawakita M, Hamard G, et al. Colorectal cancers in a new mouse model of familial adenomatous polyposis: influence of genetic and environmental modifiers. Lab Invest 2004;84:1619-30.
    • (2004) Lab Invest , vol.84 , pp. 1619-1630
    • Colnot, S.1    Niwa-Kawakita, M.2    Hamard, G.3
  • 23
    • 24044487605 scopus 로고    scopus 로고
    • Generation of a unique strain of multiple intestinal neoplasia (Apc(+/Min-FCCC)) mice with significantly increased numbers of colorectal adenomas
    • Cooper HS, Chang WC, Coudry R, et al. Generation of a unique strain of multiple intestinal neoplasia (Apc(+/Min-FCCC)) mice with significantly increased numbers of colorectal adenomas. Mol Carcinog 2005;44:31-41.
    • (2005) Mol Carcinog , vol.44 , pp. 31-41
    • Cooper, H.S.1    Chang, W.C.2    Coudry, R.3
  • 24
    • 84983146403 scopus 로고    scopus 로고
    • Polyposis in rat colon (PIRC): A robust preclinical model for chemoprevention of colorectal cancer
    • American Gastroenterology Meeting 2012
    • De La Cruz M, Wali RS, Patel AC, et al. Polyposis in rat colon (PIRC): a robust preclinical model for chemoprevention of colorectal cancer. American Gastroenterology Meeting 2012. Gastroenterology 2012;142 (Suppl 1):Abstract #886.
    • (2012) Gastroenterology , vol.142
    • De La Cruz, M.1    Wali, R.S.2    Patel, A.C.3
  • 25
    • 0032483439 scopus 로고    scopus 로고
    • Identification of c-MYC as a target of the APC pathway
    • He TC, Sparks AB, Rago C, et al. Identification of c-MYC as a target of the APC pathway. Science 1998;281:1509-12.
    • (1998) Science , vol.281 , pp. 1509-1512
    • He, T.C.1    Sparks, A.B.2    Rago, C.3
  • 26
    • 18644373146 scopus 로고    scopus 로고
    • The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells
    • van de Wetering M, Sancho E, Verweij C, et al. The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells. Cell 2002;111:241-50.
    • (2002) Cell , vol.111 , pp. 241-250
    • Van De Wetering, M.1    Sancho, E.2    Verweij, C.3
  • 27
    • 0038498213 scopus 로고    scopus 로고
    • Survivin and molecular pathogenesis of colorectal cancer
    • Kim PJ, Plescia J, Clevers H, et al. Survivin and molecular pathogenesis of colorectal cancer. Lancet 2003;362:205-9.
    • (2003) Lancet , vol.362 , pp. 205-209
    • Kim, P.J.1    Plescia, J.2    Clevers, H.3
  • 28
    • 0035893568 scopus 로고    scopus 로고
    • Evidence that APC regulates survivin expression: A possible mechanism contributing to the stem cell origin of colon cancer
    • Zhang T, Otevrel T, Gao Z, et al. Evidence that APC regulates survivin expression: a possible mechanism contributing to the stem cell origin of colon cancer. Cancer Res 2001;61:8664-7.
    • (2001) Cancer Res , vol.61 , pp. 8664-8667
    • Zhang, T.1    Otevrel, T.2    Gao, Z.3
  • 29
    • 0028849274 scopus 로고
    • p21 is necessary for the p53-mediated G1 arrest in human cancer cells
    • Waldman T, Kinzler KW, Vogelstein B. p21 is necessary for the p53-mediated G1 arrest in human cancer cells. Cancer Res 1995;55:5187-90.
    • (1995) Cancer Res , vol.55 , pp. 5187-5190
    • Waldman, T.1    Kinzler, K.W.2    Vogelstein, B.3
  • 30
    • 84864926277 scopus 로고    scopus 로고
    • New insights into p53 signaling and cancer cell response to DNA damage: Implications for cancer therapy
    • Mirzayans R, Andrais B, Scott A, et al. New insights into p53 signaling and cancer cell response to DNA damage: implications for cancer therapy. J Biomed Biotechnol 2012;2012:170325.
    • (2012) J Biomed Biotechnol , vol.2012 , pp. 170325
    • Mirzayans, R.1    Andrais, B.2    Scott, A.3
  • 31
    • 84864572894 scopus 로고    scopus 로고
    • Cyclin-dependent kinase inhibitor p21(Waf1): Contemporary view on its role in senescence and oncogenesis
    • Romanov VS, Pospelov VA, Pospelova TV. Cyclin-dependent kinase inhibitor p21(Waf1): contemporary view on its role in senescence and oncogenesis. Biochemistry (Mosc) 2012;77:575-84.
    • (2012) Biochemistry (Mosc) , vol.77 , pp. 575-584
    • Romanov, V.S.1    Pospelov, V.A.2    Pospelova, T.V.3
  • 32
    • 79952187692 scopus 로고    scopus 로고
    • WNT signaling controls expression of pro-apoptotic BOK and BAX in intestinal cancer
    • Zeilstra J, Joosten SP, Wensveen FM, et al. WNT signaling controls expression of pro-apoptotic BOK and BAX in intestinal cancer. Biochem Biophys Res Commun 2011;406:1-6.
    • (2011) Biochem Biophys Res Commun , vol.406 , pp. 1-6
    • Zeilstra, J.1    Joosten, S.P.2    Wensveen, F.M.3
  • 33
    • 0028875431 scopus 로고
    • In situ detection of enterocytic apoptosis in normal colonic mucosa and in familial adenomatous polyposis
    • Sträter J, Koretz K, Günthert AR, et al. In situ detection of enterocytic apoptosis in normal colonic mucosa and in familial adenomatous polyposis. Gut 1995;37:819-25.
    • (1995) Gut , vol.37 , pp. 819-825
    • Sträter, J.1    Koretz, K.2    Günthert, A.R.3
  • 34
    • 84883185736 scopus 로고    scopus 로고
    • Role of the oxidative DNA damage repair gene OGG1 in colorectal tumourigenesis
    • Smith CG, West H, Harris R, et al. Role of the oxidative DNA damage repair gene OGG1 in colorectal tumourigenesis. J Natl Cancer Inst 2013;105:1249-53.
    • (2013) J Natl Cancer Inst , vol.105 , pp. 1249-1253
    • Smith, C.G.1    West, H.2    Harris, R.3
  • 35
    • 4644335014 scopus 로고    scopus 로고
    • Colorectal cancer and inherited mutations in base-excision repair
    • Chow E, Thirlwell C, Macrae F, et al. Colorectal cancer and inherited mutations in base-excision repair. Lancet Oncol 2004;5:600-6.
    • (2004) Lancet Oncol , vol.5 , pp. 600-606
    • Chow, E.1    Thirlwell, C.2    Macrae, F.3
  • 36
    • 84881243404 scopus 로고    scopus 로고
    • Colon cancer progression is driven by APEX1-mediated upregulation of Jagged
    • Kim MH, Kim HB, Yoon SP, et al. Colon cancer progression is driven by APEX1-mediated upregulation of Jagged. J Clin Invest 2013;123:3211-3230.
    • (2013) J Clin Invest , vol.123 , pp. 3211-3230
    • Kim, M.H.1    Kim, H.B.2    Yoon, S.P.3
  • 37
    • 77956260388 scopus 로고    scopus 로고
    • Oxidative stress and 8-oxoguanine repair are enhanced in colon adenoma and carcinoma patients
    • Obtulowicz T, Swoboda M, Speina E, et al. Oxidative stress and 8-oxoguanine repair are enhanced in colon adenoma and carcinoma patients. Mutagenesis 2010;25:463-71.
    • (2010) Mutagenesis , vol.25 , pp. 463-471
    • Obtulowicz, T.1    Swoboda, M.2    Speina, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.