Nephrokeli, a Chinese herbal formula, may improve IgA nephropathy through regulation of the sphingosine-1-phosphate pathway

PLoS ONE

Volumn 10, Issue 1, 2015, Pages

  Zhong, Yifei ^a   Wang, Ke ^b   Zhang, Xianwen ^a   Cai, Xiaofan ^a   Chen, Yiping ^a   Deng, Yueyi ^a  

^a LONGHUA HOSPITAL AFFILIATED TO SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b SHUGUANG HOSPITAL AFFILIATED TO SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CHINESE DRUG; COLLAGEN TYPE 3; CONNECTIVE TISSUE GROWTH FACTOR; CYCLINE; LOSARTAN; MONOCYTE CHEMOTACTIC PROTEIN 1; NEPHROKELI; PLANT EXTRACT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; SPHINGOSINE 1 PHOSPHATE RECEPTOR 2; SPHINGOSINE 1 PHOSPHATE RECEPTOR 3; UNCLASSIFIED DRUG; HERBACEOUS AGENT; LYSOPHOSPHOLIPID; S1PR3 PROTEIN, RAT; SPHINGOSINE; SPHINGOSINE 1-PHOSPHATE; SPHINGOSINE-1-PHOSPHATE RECEPTOR-2, RAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG EFFECT; FEMALE; IMMUNOGLOBULIN A NEPHROPATHY; IN VITRO STUDY; KIDNEY INJURY; MESANGIUM CELL; NONHUMAN; PROTEIN DETERMINATION; PROTEIN EXPRESSION; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; ANALOGS AND DERIVATIVES; ANIMAL; DRUG EFFECTS; GLOMERULONEPHRITIS, IGA; KIDNEY; METABOLISM; PATHOLOGY; SPRAGUE DAWLEY RAT;

BOVINAE; RATTUS; STAPHYLOCOCCUS;

ANIMALS; DRUGS, CHINESE HERBAL; FEMALE; GLOMERULONEPHRITIS, IGA; KIDNEY; LYSOPHOSPHOLIPIDS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, LYSOSPHINGOLIPID; SIGNAL TRANSDUCTION; SPHINGOSINE;

EID: 84922152387     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0116873     Document Type: Article

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