Triptolide inhibits TGF-β1-induced cell proliferation in rat airway smooth muscle cells by suppressing Smad signaling

Experimental Cell Research

Volumn 331, Issue 2, 2015, Pages 362-368

  Chen, Ming ^a   Lv, Zhiqiang ^a   Huang, Linjie ^a   Zhang, Wei ^a,b   Lin, Xiaoling ^a   Shi, Jianting ^a   Liang, Ruiyun ^a   Jiang, Shanping ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b The Second Municipal Hospital of Shenzhen City   (China)

Author keywords

Airway smooth muscle cells; Asthma; Smad; TGF 1; Triptolide

Indexed keywords

SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; TRIPTOLIDE; DITERPENE; EPOXIDE; IMMUNOSUPPRESSIVE AGENT; MADH2 PROTEIN, RAT; MADH3 PROTEIN, RAT; NONSTEROID ANTIINFLAMMATORY AGENT; PHENANTHRENE DERIVATIVE; SMAD7 PROTEIN, RAT;

ADULT; AIRWAY REMODELING; ANIMAL CELL; ANIMAL MODEL; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; BREATHING MUSCLE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CELL PROLIFERATION ASSAY; CELL SYNCHRONIZATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; MALE; MTT ASSAY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; WESTERN BLOTTING; ANIMAL; ASTHMA; BIOSYNTHESIS; CELL CULTURE; DRUG EFFECTS; METABOLISM; PATHOLOGY; PHOSPHORYLATION; S PHASE CELL CYCLE CHECKPOINT; SPRAGUE DAWLEY RAT;

MURINAE; RATTUS;

AIRWAY REMODELING; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; APOPTOSIS; ASTHMA; CELL PROLIFERATION; CELLS, CULTURED; DITERPENES; EPOXY COMPOUNDS; IMMUNOSUPPRESSIVE AGENTS; MALE; MYOCYTES, SMOOTH MUSCLE; PHENANTHRENES; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; S PHASE CELL CYCLE CHECKPOINTS; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84922015819     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2014.10.016     Document Type: Article

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