Substrate stiffness influences TGF-β1-induced differentiation of bronchial fibroblasts into myofibroblasts in airway remodeling

Molecular Medicine Reports

Volumn 7, Issue 2, 2013, Pages 419-424

  Shi, Yanling ^a   Dong, Yuhui ^a   Duan, Yiyuan ^a   Jiang, Xuemei ^a   Chen, Cheng ^b   Deng, Linhong ^a,c  

^a CHONGQING UNIVERSITY   (China)

^b THIRD MILITARY MEDICAL UNIVERSITY   (China)

^c CHANGZHOU UNIVERSITY   (China)

Author keywords

Airway wall remodeling; Asthma; Differentiation; Fibroblasts; Substrate stiffness; Transforming growth factor 1

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1; DIMETICONE; MESSENGER RNA; TRANSFORMING GROWTH FACTOR BETA1;

AIRWAY REMODELING; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ASTHMA; CONTROLLED STUDY; DISEASE EXACERBATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBROBLAST CULTURE; HYPERPLASIA; MUSCLE CONTRACTILITY; MYOFIBROBLAST; NONHUMAN; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RIGIDITY; WESTERN BLOTTING; YOUNG MODULUS;

ACTINS; AIRWAY REMODELING; ANIMALS; BRONCHI; CELL DIFFERENTIATION; CELLS, CULTURED; COLLAGEN TYPE I; DIMETHYLPOLYSILOXANES; ELASTIC MODULUS; EXTRACELLULAR MATRIX PROTEINS; FIBROBLASTS; MYOFIBROBLASTS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84873830389     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2012.1213     Document Type: Article

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