Sesquiterpene lactones of Moquiniastrum polymorphum subsp. floccosum have antineoplastic effects in Walker-256 tumor-bearing rats

Chemico-Biological Interactions

Volumn 228, Issue , 2015, Pages 46-56

  Martins, Gracianny Gomes ^a   Lívero, Francislaine Aparecida Dos Reis ^a   Stolf, Aline Maria ^a   Kopruszinski, Caroline Machado ^a   Cardoso, Cibele Campos ^a   Beltrame, Olair Carlos ^a   Queiroz Telles, José Ederaldo ^a   Strapasson, Regiane Lauriano Batista ^a   Stefanello, Maria Élida Alves ^a   Oude Elferink, Ronald ^b   Acco, Alexandra ^a  

^a FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Acute toxicity (LD50); Cambar ; Cancer; Gochnatia polymorpha ssp. floccosa; Moquiniastrum polymorphum subsp. floccosum; Walker 256 tumor

Indexed keywords

ACETYLGLUCOSAMINIDASE; ALKALINE PHOSPHATASE; AMYLASE; GLUCOSE; MYELOPEROXIDASE; NITRIC OXIDE; PROTEIN BAX; PROTEIN P53; SESQUITERPENE LACTONE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; ANTINEOPLASTIC AGENT; LACTONE; SESQUITERPENE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BAX GENE; BIOCHEMISTRY; CARCINOSARCOMA; CONTROLLED STUDY; DRUG MECHANISM; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; HISTOPATHOLOGY; LD 50; MALE; MEDICINAL PLANT; MOQUINIASTRUM POLYMORPHUM FLOCCOSUM; NONHUMAN; OXIDATIVE STRESS; P53 GENE; RAT; TUMOR GROWTH; TUMOR VOLUME; ANIMAL; ASTERACEAE; BARK; CARCINOMA 256, WALKER; CELL PROLIFERATION; CHEMISTRY; CONFORMATION; DOSE RESPONSE; DRUG EFFECTS; DRUG SCREENING; ISOLATION AND PURIFICATION; MOUSE; PATHOLOGY; STRUCTURE ACTIVITY RELATION; WISTAR RAT;

GOCHNATIA POLYMORPHA; MUS; RATTUS; RATTUS NORVEGICUS;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; ASTERACEAE; CARCINOMA 256, WALKER; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; LACTONES; MALE; MICE; MOLECULAR CONFORMATION; PLANT BARK; RATS; RATS, WISTAR; SESQUITERPENES; STRUCTURE-ACTIVITY RELATIONSHIP; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84921987639     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2015.01.018     Document Type: Article

References (51)

1. C.M. Croce Oncogenes and cancer New Engl. J. Med. 358 2008 502 511
2. V. Kumar, A.K. Abbas, N. Fausto, R.N. Mitchell, Robbins & Cotran Pathologic Basis of Disease, 8th ed., Philadelphia, 2010.
3. B.A. Chabner, and T.G. Roberts Jr. Timeline: chemotherapy and the war on cancer Nat. Rev. Cancer 5 2005 65 72
4. B.A. Chabner Princípios Gerais da Quimioterapia do Câncer L.L. Brunton, B.A. Chabner, B.C. Knollmann, As Bases Farmacológicas da Terapêutica de Goodman & Gilman 2012 AMGH Porto Alegre 1667 1674
5. E.H. Romond, E.A. Perez, J. Bryant, V.J. Suman, C.E. Geyer Jr., N.E. Davidson, E. Tan-Chiu, S. Martino, S. Paik, P.A. Kaufman, S.M. Swain, T.M. Pisansky, L. Fehrenbacher, L.A. Kutteh, V.G. Vogel, D.W. Visscher, G. Yothers, R.B. Jenkins, A.M. Brown, S.R. Dakhil, E.P. Mamounas, W.L. Lingle, P.M. Klein, J.N. Ingle, and N. Wolmark Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer New Engl. J. Med. 353 2005 1673 1684
6. D.J. Slamon, B. Leyland-Jones, S. Shak, H. Fuchs, V. Paton, A. Bajamonde, T. Fleming, W. Eiermann, J. Wolter, M. Pegram, J. Baselga, and L. Norton Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2 New Engl. J. Med. 344 2001 783 792
7. M.R. Kreuger, S. Grootjans, M.W. Biavatti, P. Vandenabeele, and K. D'Herde Sesquiterpene lactones as drugs with multiple targets in cancer treatment: focus on parthenolide Anticancer Drugs 23 2012 883 896
8. S. Zhang, Y.K. Won, C.N. Ong, and H.M. Shen Anti-cancer potential of sesquiterpene lactones: bioactivity and molecular mechanisms Curr. Med. Chem. Anticancer Agents 5 2005 239 249
9. G. Sancho, V.A. Funk, and N. Roque Moquiniastrum (Gochnatieae, Asteraceae): disentangling the paraphyletic Gochnatia Phytotaxa 147 2013 26 34
10. F. Bohmann, C. Zdero, G. Schmeda-Hirschmann, J. Jakupovic, X.A. Dominguez, R.M. King, and H. Robinson Dimeric guaianolides and other constituents from Gochnatia species Phytochemistry 44 1986 1175 1178
11. C.A.N. Catalan, M.I. Vega, M.E. Lopez, M.d.R. Cuenca, T.E. Gedris, and W. Herz Coumarins and a kaurane from Gochnatia polymorpha ssp. polymorpha from Paraguay Biochem. Syst. Ecol. 31 2003 417 422
12. A.S. Moreira, V. Spitzer, E.E. Schapoval, and E.P. Schenkel Antiinflammatory activity of extracts and fractions from the leaves of Gochnatia polymorpha Phytother. Res. PTR 14 2000 638 640
13. R.R. Piornedo, P. de Souza, M.E. Stefanello, R.L. Strapasson, A.R. Zampronio, and C.A. Kassuya Anti-inflammatory activity of extracts and 11,13-dihydrozaluzanin C from Gochnatia polymorpha ssp. floccosa trunk bark in mice J. Ethnopharmacol. 133 2011 1077 1084
14. L.B. Silva, R.L.B. Strapasson, D. Riva, M.J. Salvador, and M.E.A. Stefanello Triterpenes from the flowers of Gochnatia polymorpha spp. floccosa, Revista Brasileira de Farmacognosia 21 2011
15. R.L.B. Strapasson, A.L. Rüdiger, R.A. Burrow, A. Barison, and M.E.A. Stefanello A new sesquiterpene and other constituents of Moquiniastrum polymorphum subsp. floccosum (Asteraceae) Nat. Prod. Commun. 9 2014 1541 1543
16. V. Schlemper, S.A. Freitas, and S.E.M. Schlemper Antispasmodic effects of hydroalcoholic extract from Gochnatia polymorpha ssp. floccosa in the guinea pig ileum Res. J. Med. Plant 5 2011 288 294
17. R.L. Strapasson, A.C. Cervi, J.E. Carvalho, A.L. Ruiz, M.J. Salvador, and M.E. Stefanello Bioactivity-guided isolation of cytotoxic sesquiterpene lactones of Gochnatia polymorpha ssp. floccosa Phytother. Res. PTR 26 2012 1053 1056
18. C. Vicentino, J. Constantin, A. Bracht, and N.S. Yamamoto Long-chain fatty acid uptake and oxidation in the perfused liver of Walker-256 tumour-bearing rats Liver 22 2002 341 349
19. M. Mizuno, K. Minato, H. Ito, M. Kawade, H. Terai, and H. Tsuchida Anti-tumor polysaccharide from the mycelium of liquid-cultured Agaricus blazei mill Biochem. Mol. Biol. Int. 47 1999 707 714
20. M.M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal. Biochem. 72 1976 248 254
21. H. Aebi Catalase in vitro Methods Enzymol. 105 1984 121 126
22. S.J. Gao, G.C. Zhao, G.M. Luo, T.S. Yang, and J.C. Shen Antioxidant effects of superoxide dismutase and horseradish peroxidase on lipid peroxidation Ann. N.Y. Acad. Sci. 864 1998 284 287
23. W.H. Habig, M.J. Pabst, and W.B. Jakoby Glutathione S-transferases. The first enzymatic step in mercapturic acid formation J. Biol. Chem. 249 1974 7130 7139
24. 2+ in the presence of xylenol orange. Comparison with the TBA assay and an iodometric method Lipids 26 1991 853 856
25. J. Sedlak, and R.H. Lindsay Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent Anal. Biochem. 25 1968 192 205
26. P.P. Bradley, D.A. Priebat, R.D. Christensen, and G. Rothstein Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker J. Invest. Dermatol. 78 1982 206 209
27. S. Lloret, and J.J. Moreno Effects of an anti-inflammatory peptide (antiflammin 2) on cell influx, eicosanoid biosynthesis and oedema formation by arachidonic acid and tetradecanoyl phorbol dermal application Biochem. Pharmacol. 50 1995 347 353
28. R. Korhonen, A. Lahti, H. Kankaanranta, and E. Moilanen Nitric oxide production and signaling in inflammation Curr. Drug Targets Inflamm. Allergy 4 2005 471 479
29. L.C. Green, D.A. Wagner, J. Glogowski, P.L. Skipper, J.S. Wishnok, and S.R. Tannenbaum Analysis of nitrate, nitrite, and [15N] nitrate in biological fluids Anal. Biochem. 126 1982 131 138
30. R.N. Almeida, A.C.G.M. Falcão, R.S.T. Diniz, L.J. Quintans-Júnior, R.M. Polari, J.M. Barbosa-Filho, M.F. Agra, J.C. Duarte, A.R. Antoniolli, and C.C. Araújo Metodologia para avaliação de plantas com atividade no sistema nervoso central e alguns dados experimentais Rev. Bras. Farmacogn. 80 1999 72 76
31. J.R.J.P. Litchfield, and F.A. Wilcoxon Simplified method for evaluating dose-effect experiments J. Pharmacol. Exp. Ther. 96 1949 99 113
32. C. Li, L. Dian, W. Zhang, and X. Lei Biomimetic syntheses of (-)-gochnatiolides A-C and (-)-ainsliadimer B J. Am. Chem. Soc. 134 2012 12414 12417
33. F. Balkwill, and A. Mantovani Inflammation and cancer: back to Virchow? Lancet 357 2001 539 545
34. F.R. Balkwill Cytokine therapy of cancer. The importance of knowing the context Eur. Cytokine Netw. 5 1994 379 385
35. G. Zhu, Q. Du, X. Wang, N. Tang, F. She, and Y. Chen TNF-alpha promotes gallbladder cancer cell growth and invasion through autocrine mechanisms Int. J. Mol. Med. 33 2014 1431 1440
36. M. Akiyama, T. Hideshima, T. Hayashi, Y.T. Tai, C.S. Mitsiades, N. Mitsiades, D. Chauhan, P. Richardson, N.C. Munshi, and K.C. Anderson Nuclear factor-kappaB p65 mediates tumor necrosis factor alpha-induced nuclear translocation of telomerase reverse transcriptase protein Cancer Res. 63 2003 18 21
37. S. Kim, H. Takahashi, W.W. Lin, P. Descargues, S. Grivennikov, Y. Kim, J.L. Luo, and M. Karin Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis Nature 457 2009 102 106
38. K.T.T. Trang, S.L. Kim, S.B. Park, S.Y. Seo, C.H. Choi, J.K. Park, J.C. Moon, S.T. Lee, and S.W. Kim Parthenolide sensitizes human colorectal cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through mitochondrial and caspase dependent pathway Intest. Res. 12 2014 34 41
39. Lu Li, Wenli Shi, Rahul R. Deshmukh, Jie Long, Xiaoli Cheng, Guohua Zeng, Xianliang Chen, Q. Yajie Zhang, Ping Dou, and Weidong Ji Tumor necrosis factor-sensitizes breast cancer cells to natural products with proteasome-inhibitory activity leading to apoptosis PloS One 9 2014 e113783
40. H. Nakshatri, S.E. Rice, and P. Bhat-Nakshatri Antitumor agent parthenolide reverses resistance of breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through sustained activation of c-Jun N-terminal kinase Oncogene 23 2004 7330 7344
41. V.V. Costantino, S.F. Mansilla, J. Speroni, C. Amaya, D. Cuello-Carrion, D.R. Ciocca, H.A. Priestap, M.A. Barbieri, V. Gottifredi, and L.A. Lopez The sesquiterpene lactone dehydroleucodine triggers senescence and apoptosis in association with accumulation of DNA damage markers PLoS One 8 2013 e53168
42. M.L. Guzman, R.M. Rossi, L. Karnischky, X. Li, D.R. Peterson, D.S. Howard, and C.T. Jordan The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells Blood 105 2005 4163 4169
43. M. Chadwick, H. Trewin, F. Gawthrop, and C. Wagstaff Sesquiterpenoids lactones: benefits to plants and people Int. J. Mol. Sci. 14 2013 12780 12805
44. A. Acco, A.L. Bastos-Pereira, and A.A. Dreifuss Characteristics and applications of the Walker-256 rat tumour D. Pouliquen, The Rat in Cancer Research: A Crucial Tool for All Aspects of Translational Studies 2012 Research Signpost/Transworld Research Network Trivandrum, Kerala, India 131 156
45. F.M. Jumes, D. Lugarini, A.L. Pereira, A. de Oliveira, O. Christoff Ade, G.A. Linde, J.S. do Valle, N.B. Colauto, and A. Acco Effects of Agaricus brasiliensis mushroom in Walker-256 tumor-bearing rats Can. J. Physiol. Pharmacol. 88 2010 21 27
46. P. Cassolla, C.C. Moreira, T.F. Liboni, C.T. Zaia, G.R. Borba-Murad, R.B. Bazotte, and H.M. de Souza Changes in blood metabolic parameters during the development of Walker-256 tumour-induced cachexia in rats are not caused by decreased food intake Cell Biochem. Funct. 30 2012 265 270
47. G. Jagadeesan, and A.V. Kavitha Recovery of phosphatase and transaminase activity of mercury intoxicated Mus musculus (Linn.) liver tissue by Tribulus terrestris (Linn.) (Zygophyllaceae) extract Trop. Biomed. 23 2006 45 51
48. L. Gate, J. Paul, G.N. Ba, K.D. Tew, and H. Tapiero Oxidative stress induced in pathologies: the role of antioxidants Biomed. Pharmacother. 53 1999 169 180
49. T.L. DeWeese, A.M. Hruszkewycz, and L.J. Marnett Oxidative stress in chemoprevention trials Urology 57 2001 137 140
50. P. Viveros, R. Monroy, and J. Alva Splenomegaly Rev. Fac. Med. UNAM 56 2013
51. F.C. Lu Basic Toxicology: Fundamentals, Target Organs, and Risk Assessment second ed. 1991 Taylor & Francis USA