TNF-α promotes gallbladder cancer cell growth and invasion through autocrine mechanisms

International Journal of Molecular Medicine

Volumn 33, Issue 6, 2014, Pages 1431-1440

  Zhu, Guangwei ^a   Du, Qiang ^a   Wang, Xiaoqian ^a   Tang, Nanhong ^a   She, Feifei ^a   Chen, Yanling ^a  

^a FUJIAN MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Autocrine; Gallbladder cancer cell; Invasion; Proliferation; SiRNA; Tumor necrosis factor

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; PROTEIN BCL 2; PROTEIN KINASE B; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1;

ADULT; APOPTOSIS; ARTICLE; AUTOCRINE EFFECT; CANCER GROWTH; CARCINOGENESIS; DISEASE ASSOCIATION; FEMALE; GALLBLADDER CANCER; GALLBLADDER CANCER CELL LINE; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; MIDDLE AGED; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA INTERFERENCE; TUMOR INVASION; CELL MOTION; CELL PROLIFERATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GALLBLADDER NEOPLASMS; GENETICS; METABOLISM; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL LINE; WESTERN BLOTTING;

APOPTOSIS; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GALLBLADDER NEOPLASMS; HUMANS; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84899564392     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2014.1711     Document Type: Article

References (32)

1. Donohue JH, Stewart AK and Menck HR: The National Cancer Data Base report on carcinoma of the gallbladder, 1989-1995. Cancer 83: 2618-2628, 1998. (Pubitemid 29019584)
2. Cubertafond P, Gainant A and Cucchiaro G: Surgical treatment of 724 carcinomas of the gallbladder. Results of the French Surgical Association Survey. Ann Surg 219: 275-280, 1994.
3. Bartlett DL, Fong Y, Fortner JG, Brennan MF and Blumgart LH: Long-term results after resection for gallbladder cancer. Implications for staging and management. Ann Surg 224: 639-646, 1996. (Pubitemid 26384887)
4. Egberts JH, Cloosters V, Noack A, et al: Anti-tumor necrosis factor therapy inhibits pancreatic tumor growth and metastasis. Cancer Res 68: 1443-1450, 2008. (Pubitemid 351346852)
5. Zins K, Abraham D, Sioud M and Aharinejad S: Colon cancer cell-derived tumor necrosis factor-alpha mediates the tumor growth-promoting response in macrophages by up-regulating the colony-stimulating factor-1 pathway. Cancer Res 67: 1038-1045, 2007.
6. Stathopoulos GT, Kollintza A, Moschos C, et al: Tumor necrosis factor-alpha promotes malignant pleural effusion. Cancer Res 67: 9825-9834, 2007. (Pubitemid 47621230)
7. Scott KA, Moore RJ, Arnott CH, et al: An anti-tumor necrosis factor-alpha antibody inhibits the development of experimental skin tumors. Mol Cancer Ther 2: 445-451, 2003.
8. Michalaki V, Syrigos K, Charles P and Waxman J: Serum levels of IL-6 and TNF-alpha correlate with clinicopathological features and patient survival in patients with prostate cancer. Br J Cancer 90: 2312-2316, 2004. (Pubitemid 38961893)
9. Soria G, Ofri-Shahak M, Haas I, et al: Inflammatory mediators in breast cancer: coordinated expression of TNFα and IL-1β with CCL2 & CCL5 and effects on epithelial-to-mesenchymal transition. BMC Cancer 11: 130, 2011.
10. Radhakrishnan P, Chachadi V, Lin MF, Singh R, Kannagi R and Cheng PW: TNFα enhances the motility and invasiveness of prostatic cancer cells by stimulating the expression of selective glycosyl- and sulfotransferase genes involved in the synthesis of selectin ligands. Biochem Biophys Res Commun 409: 436-441, 2011.
11. Kulbe H, Thompson R, Wilson JL, et al: The inflammatory cytokine tumor necrosis factor-alpha generates an autocrine tumor-promoting network in epithelial ovarian cancer cells. Cancer Res 67: 585-592, 2007. (Pubitemid 46192196)
12. Akiyama M, Hideshima T, Hayashi T, et al: Nuclear factor-kappaB p65 mediates tumor necrosis factor alpha-induced nuclear translocation of telomerase reverse transcriptase protein. Cancer Res 63: 18-21, 2003. (Pubitemid 36070412)
13. Li J, Sejas DP, Zhang X, et al: TNF-alpha induces leukemic clonal evolution ex vivo in Fanconi anemia group C murine stem cells. J Clin Invest 117: 3283-3295, 2007. (Pubitemid 350096985)
14. Yan B, Wang H, Rabbani ZN, et al: Tumor necrosis factor-alpha is a potent endogenous mutagen that promotes cellular transformation. Cancer Res 66: 11565-11570, 2006. (Pubitemid 46094163)
15. Komori J, Marusawa H, Machimoto T, et al: Activation-induced cytidine deaminase links bile duct inflammation to human cholangiocarcinoma. Hepatology 47: 888-896, 2008. (Pubitemid 351449680)
16. Li B, Vincent A, Cates J, Brantley-Sieders DM, Polk DB and Young PP: Low levels of tumor necrosis factor alpha increase tumor growth by inducing an endothelial phenotype of monocytes recruited to the tumor site. Cancer Res 69: 338-348, 2009.
17. Hagemann T, Wilson J, Kulbe H, et al: Macrophages induce invasiveness of epithelial cancer cells via NF-kappa B and JNK. J Immunol 175: 1197-1205, 2005. (Pubitemid 41095008)
18. Kulbe H, Hagemann T, Szlosarek PW, Balkwill FR and Wilson JL: The inflammatory cytokine tumor necrosis factoralpha regulates chemokine receptor expression on ovarian cancer cells. Cancer Res 65: 10355-10362, 2005. (Pubitemid 41743728)
19. Chua HL, Bhat-Nakshatri P, Clare SE, Morimiya A, Badve S and Nakshatri H: NF-kappaB represses E-cadherin expression and enhances epithelial to mesenchymal transition of mammary epithelial cells: potential involvement of ZEB-1 and ZEB-2. Oncogene 26: 711-724, 2007. (Pubitemid 46204250)
20. Johnston DA, Dong B and Hughes CC: TNF induction of jagged-1 in endothelial cells is NFkappaB-dependent. Gene 435: 36-44, 2009.
21. Cox GW, Melillo G, Chattopadhyay U, Mullet D, Fertel RH and Varesio L: Tumor necrosis factor-alpha-dependent production of reactive nitrogen intermediates mediates IFN-gamma plus IL-2-induced murine macrophage tumoricidal activity. J Immunol 149: 3290-3296, 1992.
22. Balkwill F: Tumor necrosis factor or tumor promoting factor? Cytokine Growth Factor Rev 13: 135-141, 2002.
23. Naylor MS, Stamp GW, Foulkes WD, Eccles D and Balkwill FR: Tumor necrosis factor and its receptors in human ovarian cancer. Potential role in disease progression. J Clin Invest 91: 2194-2206, 1993. (Pubitemid 23141496)
24. Szlosarek PW, Grimshaw MJ, Kulbe H, et al: Expression and regulation of tumor necrosis factor alpha in normal and malignant ovarian epithelium. Mol Cancer Ther 5: 382-390, 2006.
25. Homma S, Hasumura S, Nagamori S and Kameda H: Establishment and characterization of a human gall bladder carcinoma cell line NOZ. Hum Cell 1: 95-97, 1988 (In Japanese).
26. Carswell EA, Old LJ, Kassel RL, Green S, Fiore N and Williamson B: An endotoxin-induced serum factor that causes necrosis of tumors. Proc Natl Acad Sci USA: 72: 3666-3670, 1975.
27. Waters JP, Pober JS and Bradley JR: Tumour necrosis factor in infectious disease. J Pathol 230: 132-147, 2013.
28. Blonska M, Shambharkar PB, Kobayashi M, et al: TAK1 is recruited to the tumor necrosis factor-alpha (TNF-alpha) receptor 1 complex in a receptor-interacting protein (RIP)-dependent manner and cooperates with MEKK3 leading to NF-kappaB activation. J Biol Chem 280: 43056-43063, 2005. (Pubitemid 43049271)
29. Devin A, Lin Y, Yamaoka S, Li Z, Karin M and Liu Z: The alpha and beta subunits of IkappaB kinase (IKK) mediate TRAF2-dependent IKK recruitment to tumor necrosis factor (TNF) receptor 1 in response to TNF. Mol Cell Biol 21: 3986-3994, 2001. (Pubitemid 32476460)
30. Chen Y, Jiang L, She F, et al: Vascular endothelial growth factor-C promotes the growth and invasion of gallbladder cancer via an autocrine mechanism. Mol Cell Biochem 345: 77-89, 2010.
31. Lin W, Jiang L, Chen Y, et al: Vascular endothelial growth factor-D promotes growth, lymphangiogenesis and lymphatic metastasis in gallbladder cancer. Cancer Lett 314: 127-136, 2012.
32. Yao X, Zhou L, Han S and Chen Y: High expression of CXCR4 and CXCR7 predicts poor survival in gallbladder cancer. J Int Med Res 39: 1253-1264, 2011.