-
2
-
-
84893844183
-
Disentangling the heterogeneity of autism spectrum disorder through genetic findings
-
Jeste SS, Geschwind DH: Disentangling the heterogeneity of autism spectrum disorder through genetic findings. Nat Rev Neurol 2014, 10:74-81.
-
(2014)
Nat Rev Neurol
, vol.10
, pp. 74-81
-
-
Jeste, S.S.1
Geschwind, D.H.2
-
3
-
-
84893708713
-
A de novo convergence of autism genetics and molecular neuroscience
-
Krumm N, O'Roak BJ, Shendure J, Eichler EE: A de novo convergence of autism genetics and molecular neuroscience. Trends Neurosci 2014, 37:95-105.
-
(2014)
Trends Neurosci
, vol.37
, pp. 95-105
-
-
Krumm, N.1
O'Roak, B.J.2
Shendure, J.3
Eichler, E.E.4
-
4
-
-
84869213888
-
Synapse dysfunction in autism: A molecular medicine approach to drug discovery in neurodevelopmental disorders
-
Spooren W, Lindemann L, Ghosh A, Santarelli L: Synapse dysfunction in autism: a molecular medicine approach to drug discovery in neurodevelopmental disorders. Trends Pharmacol Sci 2012, 33:669-684.
-
(2012)
Trends Pharmacol Sci
, vol.33
, pp. 669-684
-
-
Spooren, W.1
Lindemann, L.2
Ghosh, A.3
Santarelli, L.4
-
5
-
-
84862637069
-
The pathophysiology of fragile X (and what it teaches us about synapses)
-
Bhakar AL, Dolen G, Bear MF: The pathophysiology of fragile X (and what it teaches us about synapses). Annu Rev Neurosci 2012, 35:417-443.
-
(2012)
Annu Rev Neurosci
, vol.35
, pp. 417-443
-
-
Bhakar, A.L.1
Dolen, G.2
Bear, M.F.3
-
6
-
-
84862659562
-
Synaptic dysfunction in neurodevelopmental disorders associated with autism and intellectual disabilities
-
Zoghbi HY, Bear MF: Synaptic dysfunction in neurodevelopmental disorders associated with autism and intellectual disabilities. Cold Spring Harb Perspect Biol 2012:4.
-
(2012)
Cold Spring Harb Perspect Biol
, pp. 4
-
-
Zoghbi, H.Y.1
Bear, M.F.2
-
7
-
-
84896722575
-
The role of ionotropic glutamate receptors in childhood neurodevelopmental disorders: Autism spectrum disorders and fragile X syndrome
-
Uzunova G, Hollander E, Shepherd J: The role of ionotropic glutamate receptors in childhood neurodevelopmental disorders: autism spectrum disorders and fragile X syndrome. Curr Neuropharmacol 2014, 12:71-98.
-
(2014)
Curr Neuropharmacol
, vol.12
, pp. 71-98
-
-
Uzunova, G.1
Hollander, E.2
Shepherd, J.3
-
8
-
-
84905042733
-
Excess of rare novel loss-of-function variants in synaptic genes in schizophrenia and autism spectrum disorders
-
Kenny EM, Cormican P, Furlong S, Heron E, Kenny G, Fahey C, Kelleher E, Ennis S, Tropea D, Anney R et al.: Excess of rare novel loss-of-function variants in synaptic genes in schizophrenia and autism spectrum disorders. Mol Psychiatry 2014, 19:872-879.
-
(2014)
Mol Psychiatry
, vol.19
, pp. 872-879
-
-
Kenny, E.M.1
Cormican, P.2
Furlong, S.3
Heron, E.4
Kenny, G.5
Fahey, C.6
Kelleher, E.7
Ennis, S.8
Tropea, D.9
Anney, R.10
-
9
-
-
84871448593
-
Multiplex targeted sequencing identifies recurrently mutated genes in autism spectrum disorders
-
O'Roak BJ, Vives L, Fu W, Egertson JD, Stanaway IB, Phelps IG, Carvill G, Kumar A, Lee C, Ankenman K et al.: Multiplex targeted sequencing identifies recurrently mutated genes in autism spectrum disorders. Science 2012, 338:1619-1622.
-
(2012)
Science
, vol.338
, pp. 1619-1622
-
-
O'Roak, B.J.1
Vives, L.2
Fu, W.3
Egertson, J.D.4
Stanaway, I.B.5
Phelps, I.G.6
Carvill, G.7
Kumar, A.8
Lee, C.9
Ankenman, K.10
-
10
-
-
84860741138
-
Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations
-
O'Roak BJ, Vives L, Girirajan S, Karakoc E, Krumm N, Coe BP, Levy R, Ko A, Lee C, Smith JD et al.: Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations. Nature 2012, 485:246-250.
-
(2012)
Nature
, vol.485
, pp. 246-250
-
-
O'Roak, B.J.1
Vives, L.2
Girirajan, S.3
Karakoc, E.4
Krumm, N.5
Coe, B.P.6
Levy, R.7
Ko, A.8
Lee, C.9
Smith, J.D.10
-
11
-
-
79957589237
-
Exome sequencing in sporadic autism spectrum disorders identifies severe de novo mutations
-
O'Roak BJ, Deriziotis P, Lee C, Vives L, Schwartz JJ, Girirajan S, Karakoc E, Mackenzie AP, Ng SB, Baker C et al.: Exome sequencing in sporadic autism spectrum disorders identifies severe de novo mutations. Nat Genet 2011, 43:585-589.
-
(2011)
Nat Genet
, vol.43
, pp. 585-589
-
-
O'Roak, B.J.1
Deriziotis, P.2
Lee, C.3
Vives, L.4
Schwartz, J.J.5
Girirajan, S.6
Karakoc, E.7
Mackenzie, A.P.8
Ng, S.B.9
Baker, C.10
-
12
-
-
81555218550
-
Rare mutations in N-methyl-D-aspartate glutamate receptors in autism spectrum disorders and schizophrenia
-
Tarabeux J, Kebir O, Gauthier J, Hamdan FF, Xiong L, Piton A, Spiegelman D, Henrion E, Millet B, team SD et al.: Rare mutations in N-methyl-D-aspartate glutamate receptors in autism spectrum disorders and schizophrenia. Transl Psychiatry 2011, 1:e55.
-
(2011)
Transl Psychiatry
, vol.1
, pp. e55
-
-
Tarabeux, J.1
Kebir, O.2
Gauthier, J.3
Hamdan, F.F.4
Xiong, L.5
Piton, A.6
Spiegelman, D.7
Henrion, E.8
Millet, B.9
-
13
-
-
84862807515
-
Family based association of GRIN2A and GRIN2B with Korean autism spectrum disorders
-
Yoo HJ, Cho IH, Park M, Yang SY, Kim SA: Family based association of GRIN2A and GRIN2B with Korean autism spectrum disorders. Neurosci Lett 2012, 512:89-93.
-
(2012)
Neurosci Lett
, vol.512
, pp. 89-93
-
-
Yoo, H.J.1
Cho, I.H.2
Park, M.3
Yang, S.Y.4
Kim, S.A.5
-
14
-
-
84878254691
-
NMDA receptor subunit diversity: Impact on receptor properties, synaptic plasticity and disease
-
Paoletti P, Bellone C, Zhou Q: NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease. Nat Rev Neurosci 2013, 14:383-400.
-
(2013)
Nat Rev Neurosci
, vol.14
, pp. 383-400
-
-
Paoletti, P.1
Bellone, C.2
Zhou, Q.3
-
15
-
-
7444237570
-
A pilot study of D-cycloserine in subjects with autistic disorder
-
Posey DJ, Kem DL, Swiezy NB, Sweeten TL, Wiegand RE, McDougle CJ: A pilot study of D-cycloserine in subjects with autistic disorder. Am J Psychiatry 2004, 161:2115-2117.
-
(2004)
Am J Psychiatry
, vol.161
, pp. 2115-2117
-
-
Posey, D.J.1
Kem, D.L.2
Swiezy, N.B.3
Sweeten, T.L.4
Wiegand, R.E.5
McDougle, C.J.6
-
16
-
-
84901333522
-
A trial of D-cycloserine to treat stereotypies in older adolescents and young adults with autism spectrum disorder
-
Urbano M, Okwara L, Manser P, Hartmann K, Herndon A, Deutsch SI: A trial of D-cycloserine to treat stereotypies in older adolescents and young adults with autism spectrum disorder. Clin Neuropharmacol 2014, 37:69-72.
-
(2014)
Clin Neuropharmacol
, vol.37
, pp. 69-72
-
-
Urbano, M.1
Okwara, L.2
Manser, P.3
Hartmann, K.4
Herndon, A.5
Deutsch, S.I.6
-
17
-
-
84876933750
-
Memantine: A review of possible uses in child and adolescent psychiatry
-
Hosenbocus S, Chahal R: Memantine: a review of possible uses in child and adolescent psychiatry. J Can Acad Child Adolesc Psychiatry 2013, 22:166-171.
-
(2013)
J Can Acad Child Adolesc Psychiatry
, vol.22
, pp. 166-171
-
-
Hosenbocus, S.1
Chahal, R.2
-
18
-
-
84873644391
-
Amantadine: A review of use in child and adolescent psychiatry
-
Hosenbocus S, Chahal R: Amantadine: a review of use in child and adolescent psychiatry. J Can Acad Child Adolesc Psychiatry 2013, 22:55-60.
-
(2013)
J Can Acad Child Adolesc Psychiatry
, vol.22
, pp. 55-60
-
-
Hosenbocus, S.1
Chahal, R.2
-
19
-
-
82555196668
-
Mutations causing syndromic autism define an axis of synaptic pathophysiology
-
Auerbach BD, Osterweil EK, Bear MF: Mutations causing syndromic autism define an axis of synaptic pathophysiology. Nature 2011, 480:63-68.
-
(2011)
Nature
, vol.480
, pp. 63-68
-
-
Auerbach, B.D.1
Osterweil, E.K.2
Bear, M.F.3
-
20
-
-
76649086962
-
Neuroligin-1 deletion results in impaired spatial memory and increased repetitive behavior
-
Blundell J, Blaiss CA, Etherton MR, Espinosa F, Tabuchi K, Walz C, Bolliger MF, Sudhof TC, Powell CM: Neuroligin-1 deletion results in impaired spatial memory and increased repetitive behavior. J Neurosci 2010, 30:2115-2129.
-
(2010)
J Neurosci
, vol.30
, pp. 2115-2129
-
-
Blundell, J.1
Blaiss, C.A.2
Etherton, M.R.3
Espinosa, F.4
Tabuchi, K.5
Walz, C.6
Bolliger, M.F.7
Sudhof, T.C.8
Powell, C.M.9
-
21
-
-
34250211762
-
Activity-dependent validation of excitatory versus inhibitory synapses by neuroligin-1 versus neuroligin-2
-
Chubykin AA, Atasoy D, Etherton MR, Brose N, Kavalali ET, Gibson JR, Sudhof TC: Activity-dependent validation of excitatory versus inhibitory synapses by neuroligin-1 versus neuroligin-2 . Neuron 2007, 54:919-931.
-
(2007)
Neuron
, vol.54
, pp. 919-931
-
-
Chubykin, A.A.1
Atasoy, D.2
Etherton, M.R.3
Brose, N.4
Kavalali, E.T.5
Gibson, J.R.6
Sudhof, T.C.7
-
22
-
-
84872200318
-
Neuroligin-1 controls synaptic abundance of NMDA-type glutamate receptors through extracellular coupling
-
Budreck EC, Kwon OB, Jung JH, Baudouin S, Thommen A, Kim HS, Fukazawa Y, Harada H, Tabuchi K, Shigemoto R et al.: Neuroligin-1 controls synaptic abundance of NMDA-type glutamate receptors through extracellular coupling . Proc Natl Acad Sci U S A 2013, 110:725-730.
-
Proc Natl Acad Sci U S A 2013
, vol.110
, pp. 725-730
-
-
Budreck, E.C.1
Kwon, O.B.2
Jung, J.H.3
Baudouin, S.4
Thommen, A.5
Kim, H.S.6
Fukazawa, Y.7
Harada, H.8
Tabuchi, K.9
Shigemoto, R.10
-
23
-
-
77952827032
-
Mutations in the SHANK2 synaptic scaffolding gene in autism spectrum disorder and mental retardation
-
Berkel S, Marshall CR, Weiss B, Howe J, Roeth R, Moog U, Endris V, Roberts W, Szatmari P, Pinto D et al.: Mutations in the SHANK2 synaptic scaffolding gene in autism spectrum disorder and mental retardation. Nat Genet 2010, 42:489-491.
-
(2010)
Nat Genet
, vol.42
, pp. 489-491
-
-
Berkel, S.1
Marshall, C.R.2
Weiss, B.3
Howe, J.4
Roeth, R.5
Moog, U.6
Endris, V.7
Roberts, W.8
Szatmari, P.9
Pinto, D.10
-
24
-
-
84862297282
-
Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function
-
Won H, Lee HR, Gee HY, Mah W, Kim JI, Lee J, Ha S, Chung C, Jung ES, Cho YS et al.: Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function. Nature 2012, 486:261-265.
-
(2012)
Nature
, vol.486
, pp. 261-265
-
-
Won, H.1
Lee, H.R.2
Gee, H.Y.3
Mah, W.4
Kim, J.I.5
Lee, J.6
Ha, S.7
Chung, C.8
Jung, E.S.9
Cho, Y.S.10
-
25
-
-
0034332480
-
Activation of metabotropic glutamate receptor 5 has direct excitatory effects and potentiates NMDA receptor currents in neurons of the subthalamic nucleus
-
Awad H, Hubert GW, Smith Y, Levey AI, Conn PJ: Activation of metabotropic glutamate receptor 5 has direct excitatory effects and potentiates NMDA receptor currents in neurons of the subthalamic nucleus. J Neurosci 2000, 20:7871-7879.
-
(2000)
J Neurosci
, vol.20
, pp. 7871-7879
-
-
Awad, H.1
Hubert, G.W.2
Smith, Y.3
Levey, A.I.4
Conn, P.J.5
-
26
-
-
50249155962
-
mGluR5 antagonists: Discovery, characterization and drug development
-
Gasparini F, Bilbe G, Gomez-Mancilla B, Spooren W: mGluR5 antagonists: discovery, characterization and drug development. Curr Opin Drug Discov Dev 2008, 11:655-665.
-
(2008)
Curr Opin Drug Discov Dev
, vol.11
, pp. 655-665
-
-
Gasparini, F.1
Bilbe, G.2
Gomez-Mancilla, B.3
Spooren, W.4
-
27
-
-
84862274500
-
Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2
-
Schmeisser MJ, Ey E, Wegener S, Bockmann J, Stempel AV, Kuebler A, Janssen AL, Udvardi PT, Shiban E, Spilker C et al.: Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2. Nature 2012, 486:256-260.
-
(2012)
Nature
, vol.486
, pp. 256-260
-
-
Schmeisser, M.J.1
Ey, E.2
Wegener, S.3
Bockmann, J.4
Stempel, A.V.5
Kuebler, A.6
Janssen, A.L.7
Udvardi, P.T.8
Shiban, E.9
Spilker, C.10
-
28
-
-
84923819589
-
Social deficits in IRSp53 mutant mice improved by NMDAR and mGluR5 suppression
-
in press
-
Chung W, Choi SY, Lee E, Park H, Kang J, Park H, Choi Y, Lee D, Park SG, Kim R et al.: Social deficits in IRSp53 mutant mice improved by NMDAR and mGluR5 suppression . Nat Neurosci, in press. http://dx.doi.org/10.1038/nn.3927
-
Nat Neurosci
-
-
Chung, W.1
Choi, S.Y.2
Lee, E.3
Park, H.4
Kang, J.5
Park, H.6
Choi, Y.7
Lee, D.8
Park, S.G.9
Kim, R.10
-
29
-
-
84893751460
-
Tbr1 haploinsufficiency impairs amygdalar axonal projections and results in cognitive abnormality
-
Huang TN, Chuang HC, Chou WH, Chen CY, Wang HF, Chou SJ, Hsueh YP: Tbr1 haploinsufficiency impairs amygdalar axonal projections and results in cognitive abnormality. Nat Neurosci 2014, 17:240-247.
-
(2014)
Nat Neurosci
, vol.17
, pp. 240-247
-
-
Huang, T.N.1
Chuang, H.C.2
Chou, W.H.3
Chen, C.Y.4
Wang, H.F.5
Chou, S.J.6
Hsueh, Y.P.7
-
30
-
-
84875721042
-
Deletion of glutamate delta-1 receptor in mouse leads to enhanced working memory and deficit in fear conditioning
-
Yadav R, Hillman BG, Gupta SC, Suryavanshi P, Bhatt JM, Pavuluri R, Stairs DJ, Dravid SM: Deletion of glutamate delta-1 receptor in mouse leads to enhanced working memory and deficit in fear conditioning. PLoS ONE 2013, 8:e60785.
-
(2013)
PLoS ONE
, vol.8
, pp. e60785
-
-
Yadav, R.1
Hillman, B.G.2
Gupta, S.C.3
Suryavanshi, P.4
Bhatt, J.M.5
Pavuluri, R.6
Stairs, D.J.7
Dravid, S.M.8
-
31
-
-
77953800799
-
Behavioural phenotyping assays for mouse models of autism
-
Silverman JL, Yang M, Lord C, Crawley JN: Behavioural phenotyping assays for mouse models of autism. Nat Rev Neurosci 2010, 11:490-502.
-
(2010)
Nat Rev Neurosci
, vol.11
, pp. 490-502
-
-
Silverman, J.L.1
Yang, M.2
Lord, C.3
Crawley, J.N.4
-
32
-
-
84878804982
-
D-Cycloserine improves sociability in the BTBR T+ Itpr3tf/J mouse model of autism spectrum disorders with altered Ras/Raf/ERK1/2 signaling
-
Burket JA, Benson AD, Tang AH, Deutsch SI: D-Cycloserine improves sociability in the BTBR T+ Itpr3tf/J mouse model of autism spectrum disorders with altered Ras/Raf/ERK1/2 signaling. Brain Res Bull 2013, 96:62-70.
-
(2013)
Brain Res Bull
, vol.96
, pp. 62-70
-
-
Burket, J.A.1
Benson, A.D.2
Tang, A.H.3
Deutsch, S.I.4
-
33
-
-
76749128438
-
Repetitive self-grooming behavior in the BTBR mouse model of autism is blocked by the mGluR5 antagonist MPEP
-
Silverman JL, Tolu SS, Barkan CL, Crawley JN: Repetitive self-grooming behavior in the BTBR mouse model of autism is blocked by the mGluR5 antagonist MPEP. Neuropsychopharmacology 2010, 35:976-989.
-
(2010)
Neuropsychopharmacology
, vol.35
, pp. 976-989
-
-
Silverman, J.L.1
Tolu, S.S.2
Barkan, C.L.3
Crawley, J.N.4
-
34
-
-
84860358233
-
Negative allosteric modulation of the mGluR5 receptor reduces repetitive behaviors and rescues social deficits in mouse models of autism
-
Silverman JL, Smith DG, Rizzo SJ, Karras MN, Turner SM, Tolu SS, Bryce DK, Smith DL, Fonseca K, Ring RH et al.: Negative allosteric modulation of the mGluR5 receptor reduces repetitive behaviors and rescues social deficits in mouse models of autism. Sci Transl Med 2012, 4:131ra151.
-
(2012)
Sci Transl Med
, vol.4
, pp. 131ra151
-
-
Silverman, J.L.1
Smith, D.G.2
Rizzo, S.J.3
Karras, M.N.4
Turner, S.M.5
Tolu, S.S.6
Bryce, D.K.7
Smith, D.L.8
Fonseca, K.9
Ring, R.H.10
-
35
-
-
84887176861
-
Balb/c mice treated with Dcycloserine arouse increased social interest in conspecifics
-
Benson AD, Burket JA, Deutsch SI: Balb/c mice treated with Dcycloserine arouse increased social interest in conspecifics. Brain Res Bull 2013, 99:95-99.
-
(2013)
Brain Res Bull
, vol.99
, pp. 95-99
-
-
Benson, A.D.1
Burket, J.A.2
Deutsch, S.I.3
-
36
-
-
84856615330
-
D-Cycloserine improves sociability and spontaneous stereotypic behaviors in 4-week old mice
-
Deutsch SI, Pepe GJ, Burket JA, Winebarger EE, Herndon AL, Benson AD: D-Cycloserine improves sociability and spontaneous stereotypic behaviors in 4-week old mice. Brain Res 2012, 1439:96-107.
-
(2012)
Brain Res
, vol.1439
, pp. 96-107
-
-
Deutsch, S.I.1
Pepe, G.J.2
Burket, J.A.3
Winebarger, E.E.4
Herndon, A.L.5
Benson, A.D.6
-
37
-
-
52949113398
-
Expression of NR1, NR2A and NR2B NMDA receptor subunits is not altered in the genetically-inbred Balb/c mouse strain with heightened behavioral sensitivity to MK-801, a noncompetitive NMDA receptor antagonist
-
Perera PY, Lichy JH, Mastropaolo J, Rosse RB, Deutsch SI: Expression of NR1, NR2A and NR2B NMDA receptor subunits is not altered in the genetically-inbred Balb/c mouse strain with heightened behavioral sensitivity to MK-801, a noncompetitive NMDA receptor antagonist. Eur Neuropsychopharmacol 2008, 18:814-819.
-
(2008)
Eur Neuropsychopharmacol
, vol.18
, pp. 814-819
-
-
Perera, P.Y.1
Lichy, J.H.2
Mastropaolo, J.3
Rosse, R.B.4
Deutsch, S.I.5
-
38
-
-
84880331581
-
Rats selectively bred for low levels of play-induced 50 kHz vocalizations as a model for autism spectrum disorders: A role for NMDA receptors
-
Burgdorf J, Moskal JR, Brudzynski SM, Panksepp J: Rats selectively bred for low levels of play-induced 50 kHz vocalizations as a model for autism spectrum disorders: a role for NMDA receptors. Behav Brain Res 2013, 251:18-24.
-
(2013)
Behav Brain Res
, vol.251
, pp. 18-24
-
-
Burgdorf, J.1
Moskal, J.R.2
Brudzynski, S.M.3
Panksepp, J.4
-
39
-
-
0033946468
-
Proteomic analysis of NMDA receptor-adhesion protein signaling complexes
-
Husi H, Ward MA, Choudhary JS, Blackstock WP, Grant SG: Proteomic analysis of NMDA receptor-adhesion protein signaling complexes. Nat Neurosci 2000, 3:661-669.
-
(2000)
Nat Neurosci
, vol.3
, pp. 661-669
-
-
Husi, H.1
Ward, M.A.2
Choudhary, J.S.3
Blackstock, W.P.4
Grant, S.G.5
-
40
-
-
80052563319
-
Neocortical excitation/inhibition balance in information processing and social dysfunction
-
Yizhar O, Fenno LE, Prigge M, Schneider F, Davidson TJ, O'Shea DJ, Sohal VS, Goshen I, Finkelstein J, Paz JT et al.: Neocortical excitation/inhibition balance in information processing and social dysfunction. Nature 2011, 477:171-178.
-
(2011)
Nature
, vol.477
, pp. 171-178
-
-
Yizhar, O.1
Fenno, L.E.2
Prigge, M.3
Schneider, F.4
Davidson, T.J.5
O'Shea, D.J.6
Sohal, V.S.7
Goshen, I.8
Finkelstein, J.9
Paz, J.T.10
-
41
-
-
84887841772
-
Loss of predominant Shank3 isoforms results in hippocampusdependent impairments in behavior and synaptic transmission
-
Kouser M, Speed HE, Dewey CM, Reimers JM, Widman AJ, Gupta N, Liu S, Jaramillo TC, Bangash M, Xiao B et al.: Loss of predominant Shank3 isoforms results in hippocampusdependent impairments in behavior and synaptic transmission . J Neurosci 2013, 33:18448-18468.
-
(2013)
J Neurosci
, vol.33
, pp. 18448-18468
-
-
Kouser, M.1
Speed, H.E.2
Dewey, C.M.3
Reimers, J.M.4
Widman, A.J.5
Gupta, N.6
Liu, S.7
Jaramillo, T.C.8
Bangash, M.9
Xiao, B.10
-
42
-
-
35148858044
-
A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice
-
Tabuchi K, Blundell J, Etherton MR, Hammer RE, Liu X, Powell CM, Sudhof TC: A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice . Science 2007, 318:71-76.
-
(2007)
Science
, vol.318
, pp. 71-76
-
-
Tabuchi, K.1
Blundell, J.2
Etherton, M.R.3
Hammer, R.E.4
Liu, X.5
Powell, C.M.6
Sudhof, T.C.7
-
43
-
-
84898917488
-
Autism-related neuroligin-3 mutation alters social behavior and spatial learning
-
Jaramillo TC, Liu S, Pettersen A, Birnbaum SG, Powell CM: Autism-related neuroligin-3 mutation alters social behavior and spatial learning. Autism Res 2014, 7:264-272.
-
(2014)
Autism Res
, vol.7
, pp. 264-272
-
-
Jaramillo, T.C.1
Liu, S.2
Pettersen, A.3
Birnbaum, S.G.4
Powell, C.M.5
-
44
-
-
80051998693
-
Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function
-
Etherton M, Foldy C, Sharma M, Tabuchi K, Liu X, Shamloo M, Malenka RC, Sudhof TC: Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function. Proc Natl Acad Sci U S A 2011, 108:13764-13769.
-
Proc Natl Acad Sci U S A 2011
, vol.108
, pp. 13764-13769
-
-
Etherton, M.1
Foldy, C.2
Sharma, M.3
Tabuchi, K.4
Liu, X.5
Shamloo, M.6
Malenka, R.C.7
Sudhof, T.C.8
-
45
-
-
84877336575
-
Autism-associated neuroligin-3 mutations commonly disrupt tonic endocannabinoid signaling
-
Foldy C, Malenka RC, Sudhof TC: Autism-associated neuroligin-3 mutations commonly disrupt tonic endocannabinoid signaling. Neuron 2013, 78:498-509.
-
(2013)
Neuron
, vol.78
, pp. 498-509
-
-
Foldy, C.1
Malenka, R.C.2
Sudhof, T.C.3
-
46
-
-
84904004407
-
Autism-associated neuroligin-3 mutations commonly impair striatal circuits to boost repetitive behaviors
-
Rothwell PE, Fuccillo MV, Maxeiner S, Hayton SJ, Gokce O, Lim BK, Fowler SC, Malenka RC, Sudhof TC: Autism-associated neuroligin-3 mutations commonly impair striatal circuits to boost repetitive behaviors. Cell 2014, 158:198-212.
-
(2014)
Cell
, vol.158
, pp. 198-212
-
-
Rothwell, P.E.1
Fuccillo, M.V.2
Maxeiner, S.3
Hayton, S.J.4
Gokce, O.5
Lim, B.K.6
Fowler, S.C.7
Malenka, R.C.8
Sudhof, T.C.9
-
47
-
-
60349108540
-
Synaptic ionotropic glutamate receptors and plasticity are developmentally altered in the CA1 field of Fmr1 knockout mice
-
Pilpel Y, Kolleker A, Berberich S, Ginger M, Frick A, Mientjes E, Oostra BA, Seeburg PH: Synaptic ionotropic glutamate receptors and plasticity are developmentally altered in the CA1 field of Fmr1 knockout mice. J Physiol 2009, 587:787-804.
-
(2009)
J Physiol
, vol.587
, pp. 787-804
-
-
Pilpel, Y.1
Kolleker, A.2
Berberich, S.3
Ginger, M.4
Frick, A.5
Mientjes, E.6
Oostra, B.A.7
Seeburg, P.H.8
-
48
-
-
34548085412
-
Elevated NMDA receptor levels and enhanced postsynaptic long-term potentiation induced by prenatal exposure to valproic acid
-
Rinaldi T, Kulangara K, Antoniello K, Markram H: Elevated NMDA receptor levels and enhanced postsynaptic long-term potentiation induced by prenatal exposure to valproic acid. Proc Natl Acad Sci U S A 2007, 104:13501-13506.
-
Proc Natl Acad Sci U S A 2007
, vol.104
, pp. 13501-13506
-
-
Rinaldi, T.1
Kulangara, K.2
Antoniello, K.3
Markram, H.4
-
49
-
-
80053929841
-
mGluR5-antagonist mediated reversal of elevated stereotyped, repetitive behaviors in the VPA model of autism
-
Mehta MV, Gandal MJ, Siegel SJ: mGluR5-antagonist mediated reversal of elevated stereotyped, repetitive behaviors in the VPA model of autism. PLoS ONE 2011, 6:e26077.
-
(2011)
PLoS ONE
, vol.6
, pp. e26077
-
-
Mehta, M.V.1
Gandal, M.J.2
Siegel, S.J.3
-
50
-
-
84867229875
-
Shared synaptic pathophysiology in syndromic and nonsyndromic rodent models of autism
-
Baudouin SJ, Gaudias J, Gerharz S, Hatstatt L, Zhou K, Punnakkal P, Tanaka KF, Spooren W, Hen R, De Zeeuw CI et al.: Shared synaptic pathophysiology in syndromic and nonsyndromic rodent models of autism. Science 2012, 338:128-132.
-
(2012)
Science
, vol.338
, pp. 128-132
-
-
Baudouin, S.J.1
Gaudias, J.2
Gerharz, S.3
Hatstatt, L.4
Zhou, K.5
Punnakkal, P.6
Tanaka, K.F.7
Spooren, W.8
Hen, R.9
De Zeeuw, C.I.10
-
51
-
-
84869038551
-
Pathogenic SYNGAP1 mutations impair cognitive development by disrupting maturation of dendritic spine synapses
-
Clement JP, Aceti M, Creson TK, Ozkan ED, Shi Y, Reish NJ, Almonte AG, Miller BH, Wiltgen BJ, Miller CA et al.: Pathogenic SYNGAP1 mutations impair cognitive development by disrupting maturation of dendritic spine synapses. Cell 2012, 151:709-723.
-
(2012)
Cell
, vol.151
, pp. 709-723
-
-
Clement, J.P.1
Aceti, M.2
Creson, T.K.3
Ozkan, E.D.4
Shi, Y.5
Reish, N.J.6
Almonte, A.G.7
Miller, B.H.8
Wiltgen, B.J.9
Miller, C.A.10
-
52
-
-
84863279487
-
Deletion of glutamate delta-1 receptor in mouse leads to aberrant emotional and social behaviors
-
Yadav R, Gupta SC, Hillman BG, Bhatt JM, Stairs DJ, Dravid SM: Deletion of glutamate delta-1 receptor in mouse leads to aberrant emotional and social behaviors. PLoS ONE 2012, 7:e32969.
-
(2012)
PLoS ONE
, vol.7
, pp. e32969
-
-
Yadav, R.1
Gupta, S.C.2
Hillman, B.G.3
Bhatt, J.M.4
Stairs, D.J.5
Dravid, S.M.6
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