Enhanced amphiphilic profile of a short β-stranded peptide improves its antimicrobial activity

PLoS ONE

Volumn 10, Issue 1, 2015, Pages

  Manzo, Giorgia ^a   Scorciapino, Mariano A ^a   Wadhwani, Parvesh ^b   Bürck, Jochen ^b   Montaldo, Nicola Pietro ^a   Pintus, Manuela ^a   Sanna, Roberta ^a   Casu, Mariano ^a   Giuliani, Andrea ^c   Pirri, Giovanna ^c   Luca, Vincenzo ^d   Ulrich, Anne S ^b   Rinaldi, Andrea C ^a  

^a UNIVERSITY OF CAGLIARI   (Italy)

^b KARLSRUHE INSTITUTE OF TECHNOLOGY   (Germany)

^c SpiderBiotech Srl   (Italy)

^d SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; BETA SB 056; COLISTIN; POLYMYXIN B; POLYPEPTIDE ANTIBIOTIC AGENT; SB 056; UNCLASSIFIED DRUG; HEMOLYTIC AGENT; PEPTIDE; SURFACTANT;

AMPHIPATHICITY; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL GROWTH; BETA SHEET; BINDING AFFINITY; CHEMICAL REACTION; CONTROLLED STUDY; DRUG CONFORMATION; DRUG IDENTIFICATION; DRUG PROTEIN BINDING; DRUG SYNTHESIS; ENTEROCOCCUS FAECALIS; ESCHERICHIA COLI; FLUORESCENCE ANALYSIS; FLUORINE NUCLEAR MAGNETIC RESONANCE; GROWTH INHIBITION; HUMAN; HUMAN CELL; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; STATIC ELECTRICITY; CHEMISTRY; CIRCULAR DICHROISM; DRUG EFFECTS; ERYTHROCYTE; MICROBIAL SENSITIVITY TEST; NUCLEAR MAGNETIC RESONANCE; PROTEIN SECONDARY STRUCTURE; SEQUENCE ANALYSIS;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; POSIBACTERIA;

ANTI-INFECTIVE AGENTS; CIRCULAR DICHROISM; ERYTHROCYTES; ESCHERICHIA COLI; HEMOLYTIC AGENTS; HUMANS; MICROBIAL SENSITIVITY TESTS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PEPTIDES; PROTEIN STRUCTURE, SECONDARY; PSEUDOMONAS AERUGINOSA; SEQUENCE ANALYSIS, PROTEIN; STAPHYLOCOCCUS AUREUS; SURFACE-ACTIVE AGENTS;

EID: 84921940501     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0116379     Document Type: Article

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