Orientation of the antimicrobial peptide PGLa in lipid membranes determined from 19F-NMR dipolar couplings of 4-CF3-phenylglycine labels

Journal of Magnetic Resonance

Volumn 168, Issue 1, 2004, Pages 153-163

  Glaser, Ralf W ^a   Sachse, Carsten ^a   Dürr, Ulrich H N ^b   Wadhwani, Parvesh ^c   Ulrich, Anne S ^b,c  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^b UNIVERSITY OF KARLSRUHE   (Germany)

^c KARLSRUHE INSTITUTE OF TECHNOLOGY   (Germany)

Author keywords

4 Trifluoromethyl phenylglycine; Antimicrobial peptide PGLa; Lipid bilayer membrane; Orientational constraints; Solid state 19F NMR

Indexed keywords

AMINO ACIDS; AROMATIC COMPOUNDS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROPHILICITY; HYDROPHOBICITY; NUCLEAR MAGNETIC RESONANCE; POLYMERIC MEMBRANES; PURIFICATION; SYNTHESIS (CHEMICAL);

4-TRIFLUOROMETHYL-PHENYLGYCINE; ANTIMICROBIAL PEPTIDE PGLA; LIPID BILAYER MEMBRANES; ORIENTATIONAL CONSTRAINTS; SOLID-STATE 19F-NMR;

LIPIDS;

4 TRIFLUOROMETHYLPHENYLGLYCINE; 4-TRIFLUOROMETHYLPHENYLGLYCINE; ANTIINFECTIVE AGENT; ANTIMICROBIAL CATIONIC PEPTIDE; DIMYRISTOYLPHOSPHATIDYLCHOLINE; DRUG DERIVATIVE; FLUORINE; GLYCINE; MEMBRANE LIPID; PEPTIDE GLY LEU AMIDE; PEPTIDE-GLY-LEU-AMIDE;

ARTICLE; ARTIFICIAL MEMBRANE; CHEMISTRY; COMPARATIVE STUDY; EVALUATION; ISOTOPE LABELING; MACROMOLECULE; MEMBRANE FLUIDITY; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN CONFORMATION; SPIN LABELING;

ANTI-INFECTIVE AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; DIMYRISTOYLPHOSPHATIDYLCHOLINE; FLUORINE RADIOISOTOPES; GLYCINE; ISOTOPE LABELING; MACROMOLECULAR SUBSTANCES; MAGNETIC RESONANCE SPECTROSCOPY; MEMBRANE FLUIDITY; MEMBRANE LIPIDS; MEMBRANES, ARTIFICIAL; PROTEIN CONFORMATION; SPIN LABELS;

EID: 1842783092     PISSN: 10907807     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmr.2004.02.008     Document Type: Article

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