-
1
-
-
43149103482
-
Medulloblastoma
-
Louis DN, Ohgaki H, Wiestler OD, Cavanee WK, (eds), IARC, Lyon:
-
Giangaspero F, Eberhart CG, Haapasalo H, Pietsch T, Wiestler OD, Ellison DW (2007) Medulloblastoma. In: Louis DN, Ohgaki H, Wiestler OD, Cavanee WK (eds) WHO classification of tumors of the central nervous system. IARC, Lyon, pp 132–140
-
(2007)
WHO classification of tumors of the central nervous system
, pp. 132-140
-
-
Giangaspero, F.1
Eberhart, C.G.2
Haapasalo, H.3
Pietsch, T.4
Wiestler, O.D.5
Ellison, D.W.6
-
2
-
-
41749098048
-
The origins of medulloblastoma subtypes
-
COI: 1:CAS:528:DC%2BD1cXjsFersLo%3D, PID: 18039127
-
Gilbertson RJ, Ellison DW (2008) The origins of medulloblastoma subtypes. Annu Rev Pathol 3:341–365
-
(2008)
Annu Rev Pathol
, vol.3
, pp. 341-365
-
-
Gilbertson, R.J.1
Ellison, D.W.2
-
3
-
-
83055194621
-
p53 expression predicts dismal outcome for medulloblastoma patients with metastatic disease
-
COI: 1:CAS:528:DC%2BC3MXhsFantrbM, PID: 21796446
-
Gessi M, von Bueren AO, Rutkowski S, Pietsch T (2012) p53 expression predicts dismal outcome for medulloblastoma patients with metastatic disease. J Neurooncol 106:135–140
-
(2012)
J Neurooncol
, vol.106
, pp. 135-140
-
-
Gessi, M.1
von Bueren, A.O.2
Rutkowski, S.3
Pietsch, T.4
-
4
-
-
1642307767
-
Medulloblastoma: signalling a change in treatment
-
PID: 15050952
-
Gilbertson RJ (2004) Medulloblastoma: signalling a change in treatment. Lancet Oncol 5:209–218
-
(2004)
Lancet Oncol
, vol.5
, pp. 209-218
-
-
Gilbertson, R.J.1
-
5
-
-
79955034739
-
Medulloblastoma comprises four distinct molecular variants
-
PID: 20823417
-
Northcott PA, Korshunov A, Witt H, Hielscher T, Eberhart CG, Mack S, Bouffet E, Clifford SC, Hawkins CE, French P, Rutka JT, Pfister S, Taylor MD (2011) Medulloblastoma comprises four distinct molecular variants. J Clin Oncol 29:1408–1414
-
(2011)
J Clin Oncol
, vol.29
, pp. 1408-1414
-
-
Northcott, P.A.1
Korshunov, A.2
Witt, H.3
Hielscher, T.4
Eberhart, C.G.5
Mack, S.6
Bouffet, E.7
Clifford, S.C.8
Hawkins, C.E.9
French, P.10
Rutka, J.T.11
Pfister, S.12
Taylor, M.D.13
-
6
-
-
78149411577
-
Molecular diagnostics of CNS embryonal tumors
-
COI: 1:CAS:528:DC%2BC3cXhtlSjtrfJ, PID: 20882288
-
Pfister SM, Korshunov A, Kool M, Hasselblatt M, Eberhart C, Taylor MD (2010) Molecular diagnostics of CNS embryonal tumors. Acta Neuropathol 120:553–566
-
(2010)
Acta Neuropathol
, vol.120
, pp. 553-566
-
-
Pfister, S.M.1
Korshunov, A.2
Kool, M.3
Hasselblatt, M.4
Eberhart, C.5
Taylor, M.D.6
-
7
-
-
78649991959
-
Molecular diagnostics in embryonal brain tumors
-
PID: 21129063
-
Eberhart CG (2011) Molecular diagnostics in embryonal brain tumors. Brain Pathol 21:96–104
-
(2011)
Brain Pathol
, vol.21
, pp. 96-104
-
-
Eberhart, C.G.1
-
8
-
-
78650811198
-
Subtypes of medulloblastoma have distinct developmental origins
-
COI: 1:CAS:528:DC%2BC3cXhsFGgt77N, PID: 21150899
-
Gibson P, Tong Y, Robinson G, Thompson MC, Currle DS, Eden C, Kranenburg TA, Hogg T, Poppleton H, Martin J, Finkelstein D, Pounds S, Weiss A, Patay Z, Scoggins M, Ogg R, Pei Y, Yang ZJ, Brun S, Lee Y, Zindy F, Lindsey JC, Taketo MM, Boop FA, Sanford RA, Gajjar A, Clifford SC, Roussel MF, McKinnon PJ, Gutmann DH, Ellison DW, Wechsler-Reya R, Gilbertson RJ (2010) Subtypes of medulloblastoma have distinct developmental origins. Nature 468:1095–1099
-
(2010)
Nature
, vol.468
, pp. 1095-1099
-
-
Gibson, P.1
Tong, Y.2
Robinson, G.3
Thompson, M.C.4
Currle, D.S.5
Eden, C.6
Kranenburg, T.A.7
Hogg, T.8
Poppleton, H.9
Martin, J.10
Finkelstein, D.11
Pounds, S.12
Weiss, A.13
Patay, Z.14
Scoggins, M.15
Ogg, R.16
Pei, Y.17
Yang, Z.J.18
Brun, S.19
Lee, Y.20
Zindy, F.21
Lindsey, J.C.22
Taketo, M.M.23
Boop, F.A.24
Sanford, R.A.25
Gajjar, A.26
Clifford, S.C.27
Roussel, M.F.28
McKinnon, P.J.29
Gutmann, D.H.30
Ellison, D.W.31
Wechsler-Reya, R.32
Gilbertson, R.J.33
more..
-
9
-
-
79954444747
-
Medulloblastoma: clinicopathological correlates of SHH, WNT, and non-SHH/WNT molecular subgroups
-
COI: 1:CAS:528:DC%2BC3MXhvVyrsrg%3D, PID: 21267586
-
Ellison DW, Dalton J, Kocak M, Nicholson SL, Fraga C, Neale G, Kenney AM, Brat DJ, Perry A, Yong WH, Taylor RE, Bailey S, Clifford SC, Gilbertson RJ (2011) Medulloblastoma: clinicopathological correlates of SHH, WNT, and non-SHH/WNT molecular subgroups. Acta Neuropathol 121:381–396
-
(2011)
Acta Neuropathol
, vol.121
, pp. 381-396
-
-
Ellison, D.W.1
Dalton, J.2
Kocak, M.3
Nicholson, S.L.4
Fraga, C.5
Neale, G.6
Kenney, A.M.7
Brat, D.J.8
Perry, A.9
Yong, W.H.10
Taylor, R.E.11
Bailey, S.12
Clifford, S.C.13
Gilbertson, R.J.14
-
10
-
-
84863393028
-
Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas
-
COI: 1:CAS:528:DC%2BC38XktlaqsL4%3D, PID: 22358457
-
Kool M, Korshunov A, Remke M, Jones DT, Schlanstein M, Northcott PA, Cho YJ, Koster J, Schouten-van Meeteren A, van Vuurden D, Clifford SC, Pietsch T, von Bueren AO, Rutkowski S, McCabe M, Collins VP, Bäcklund ML, Haberler C, Bourdeaut F, Delattre O, Doz F, Ellison DW, Gilbertson RJ, Pomeroy SL, Taylor MD, Lichter P, Pfister SM (2012) Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas. Acta Neuropathol 123:473–484
-
(2012)
Acta Neuropathol
, vol.123
, pp. 473-484
-
-
Kool, M.1
Korshunov, A.2
Remke, M.3
Jones, D.T.4
Schlanstein, M.5
Northcott, P.A.6
Cho, Y.J.7
Koster, J.8
Schouten-van Meeteren, A.9
van Vuurden, D.10
Clifford, S.C.11
Pietsch, T.12
von Bueren, A.O.13
Rutkowski, S.14
McCabe, M.15
Collins, V.P.16
Bäcklund, M.L.17
Haberler, C.18
Bourdeaut, F.19
Delattre, O.20
Doz, F.21
Ellison, D.W.22
Gilbertson, R.J.23
Pomeroy, S.L.24
Taylor, M.D.25
Lichter, P.26
Pfister, S.M.27
more..
-
11
-
-
32944461274
-
Beta-catenin status predicts a favorable outcome in childhood medulloblastoma: the United Kingdom Children’s Cancer Study Group Brain Tumor Committee
-
COI: 1:CAS:528:DC%2BD2MXht1CqsL7P, PID: 16258095
-
Ellison DW, Onilude OE, Lindsey JC, Lusher ME, Weston CL, Taylor RE, Pearson AD, Clifford SC, United Kingdom Children’s Cancer Study Group Brain Tumour Committee (2005) Beta-catenin status predicts a favorable outcome in childhood medulloblastoma: the United Kingdom Children’s Cancer Study Group Brain Tumor Committee. J Clin Oncol 23:7951–7957
-
(2005)
J Clin Oncol
, vol.23
, pp. 7951-7957
-
-
Ellison, D.W.1
Onilude, O.E.2
Lindsey, J.C.3
Lusher, M.E.4
Weston, C.L.5
Taylor, R.E.6
Pearson, A.D.7
Clifford, S.C.8
United Kingdom Children’s Cancer Study Group Brain Tumour Committee9
-
12
-
-
65849356587
-
Beta-catenin status in pediatric medulloblastomas: correlation of immunohistochemical expression with mutational status, genetic profiles, and clinical characteristics
-
COI: 1:CAS:528:DC%2BD1MXls1Ort7g%3D, PID: 19197950
-
Fattet S, Haberler C, Legoix P, Varlet P, Lellouch-Tubiana A, Lair S, Manie E, Raquin MA, Bours D, Carpentier S, Barillot E, Grill J, Doz F, Puget S, Janoueix-Lerosey I, Delattre O (2009) Beta-catenin status in pediatric medulloblastomas: correlation of immunohistochemical expression with mutational status, genetic profiles, and clinical characteristics. J Pathol 218:86–94
-
(2009)
J Pathol
, vol.218
, pp. 86-94
-
-
Fattet, S.1
Haberler, C.2
Legoix, P.3
Varlet, P.4
Lellouch-Tubiana, A.5
Lair, S.6
Manie, E.7
Raquin, M.A.8
Bours, D.9
Carpentier, S.10
Barillot, E.11
Grill, J.12
Doz, F.13
Puget, S.14
Janoueix-Lerosey, I.15
Delattre, O.16
-
13
-
-
33646362581
-
Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations
-
COI: 1:CAS:528:DC%2BD28XkvVajtbY%3D, PID: 16567768
-
Thompson MC, Fuller C, Hogg TL, Dalton J, Finkelstein D, Lau CC, Chintagumpala M, Adesina A, Ashley DM, Kellie SJ, Taylor MD, Curran T, Gajjar A, Gilbertson RJ (2006) Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations. J Clin Oncol 24:1924–1931
-
(2006)
J Clin Oncol
, vol.24
, pp. 1924-1931
-
-
Thompson, M.C.1
Fuller, C.2
Hogg, T.L.3
Dalton, J.4
Finkelstein, D.5
Lau, C.C.6
Chintagumpala, M.7
Adesina, A.8
Ashley, D.M.9
Kellie, S.J.10
Taylor, M.D.11
Curran, T.12
Gajjar, A.13
Gilbertson, R.J.14
-
14
-
-
83055173058
-
Norcantharidin impairs medulloblastoma growth by inhibition of Wnt/b-catenin signaling
-
COI: 1:CAS:528:DC%2BC3MXhsFantrnK, PID: 21735115
-
Cimmino F, Scoppettuolo MN, Carotenuto M, De Antonellis P, Dato VD, De Vita G, Zollo M (2012) Norcantharidin impairs medulloblastoma growth by inhibition of Wnt/b-catenin signaling. J Neurooncol 106:59–70
-
(2012)
J Neurooncol
, vol.106
, pp. 59-70
-
-
Cimmino, F.1
Scoppettuolo, M.N.2
Carotenuto, M.3
De Antonellis, P.4
Dato, V.D.5
De Vita, G.6
Zollo, M.7
-
15
-
-
33751234205
-
Wnt/Wingless pathway activation and chromosome 6 loss characterize a distinct molecular sub-group of medulloblastomas associated with a favorable prognosis
-
COI: 1:CAS:528:DC%2BD2sXhslyhsLY%3D, PID: 17172831
-
Clifford SC, Lusher ME, Lindsey JC, Langdon JA, Gilbertson RJ, Straughton D, Ellison DW (2006) Wnt/Wingless pathway activation and chromosome 6 loss characterize a distinct molecular sub-group of medulloblastomas associated with a favorable prognosis. Cell Cycle 5:2666–2670
-
(2006)
Cell Cycle
, vol.5
, pp. 2666-2670
-
-
Clifford, S.C.1
Lusher, M.E.2
Lindsey, J.C.3
Langdon, J.A.4
Gilbertson, R.J.5
Straughton, D.6
Ellison, D.W.7
-
16
-
-
52449119078
-
Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features
-
PID: 18769486
-
Kool M, Koster J, Bunt J, Hasselt NE, Lakeman A, van Sluis P, Troost D, Meeteren NS, Caron HN, Cloos J, Mrsić A, Ylstra B, Grajkowska W, Hartmann W, Pietsch T, Ellison D, Clifford SC, Versteeg R (2008) Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features. PLoS One 3:e3088
-
(2008)
PLoS One
, vol.3
, pp. 3088
-
-
Kool, M.1
Koster, J.2
Bunt, J.3
Hasselt, N.E.4
Lakeman, A.5
van Sluis, P.6
Troost, D.7
Meeteren, N.S.8
Caron, H.N.9
Cloos, J.10
Mrsić, A.11
Ylstra, B.12
Grajkowska, W.13
Hartmann, W.14
Pietsch, T.15
Ellison, D.16
Clifford, S.C.17
Versteeg, R.18
-
17
-
-
64949083548
-
An investigation of WNT pathway activation and association with survival in central nervous system primitive neuroectodermal tumours (CNS PNET)
-
COI: 1:CAS:528:DC%2BD1MXksF2gtrk%3D, PID: 19293793
-
Rogers HA, Miller S, Lowe J, Brundler MA, Coyle B, Grundy RG (2009) An investigation of WNT pathway activation and association with survival in central nervous system primitive neuroectodermal tumours (CNS PNET). Br J Cancer 100:1292–1302
-
(2009)
Br J Cancer
, vol.100
, pp. 1292-1302
-
-
Rogers, H.A.1
Miller, S.2
Lowe, J.3
Brundler, M.A.4
Coyle, B.5
Grundy, R.G.6
-
18
-
-
0029553905
-
Establishment and characterization of four human medulloblastoma-derived cell lines
-
COI: 1:CAS:528:DyaK28Xit1ertr4%3D, PID: 8866661
-
Keles GE, Berger MS, Srinivasan J, Kolstoe DD, Bobola MS, Silber JR (1995) Establishment and characterization of four human medulloblastoma-derived cell lines. Oncol Res 7:493–503
-
(1995)
Oncol Res
, vol.7
, pp. 493-503
-
-
Keles, G.E.1
Berger, M.S.2
Srinivasan, J.3
Kolstoe, D.D.4
Bobola, M.S.5
Silber, J.R.6
-
19
-
-
11144355390
-
Illegitimate WNT signaling promotes proliferation of multiple myeloma cells
-
COI: 1:CAS:528:DC%2BD2cXjsFKnt74%3D, PID: 15067127
-
Derksen PW, Tjin E, Meijer HP, Klok MD, MacGillavry HD, van Oers MH, Lokhorst HM, Bloem AC, Clevers H, Nusse R, van der Neut R, Spaargaren M, Pals ST (2004) Illegitimate WNT signaling promotes proliferation of multiple myeloma cells. Proc Natl Acad Sci USA 101:6122–6127
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 6122-6127
-
-
Derksen, P.W.1
Tjin, E.2
Meijer, H.P.3
Klok, M.D.4
MacGillavry, H.D.5
van Oers, M.H.6
Lokhorst, H.M.7
Bloem, A.C.8
Clevers, H.9
Nusse, R.10
van der Neut, R.11
Spaargaren, M.12
Pals, S.T.13
-
20
-
-
56249131423
-
Radiobiologic response of medulloblastoma cell lines: involvement of beta-catenin?
-
COI: 1:CAS:528:DC%2BD1cXhsFChs73J, PID: 18688572
-
Salaroli R, Di Tomaso T, Ronchi A, Ceccarelli C, Cammelli S, Cappellini A, Martinelli GN, Barbieri E, Giangaspero F, Cenacchi G (2008) Radiobiologic response of medulloblastoma cell lines: involvement of beta-catenin? J Neurooncol 90:243–251
-
(2008)
J Neurooncol
, vol.90
, pp. 243-251
-
-
Salaroli, R.1
Di Tomaso, T.2
Ronchi, A.3
Ceccarelli, C.4
Cammelli, S.5
Cappellini, A.6
Martinelli, G.N.7
Barbieri, E.8
Giangaspero, F.9
Cenacchi, G.10
-
21
-
-
0023187867
-
A rapid in vitro assay for quantitating the invasive potential of tumor cells
-
COI: 1:STN:280:DyaL2s3hsFKhtQ%3D%3D, PID: 2438036
-
Albini A, Iwamoto Y, Kleinman HK et al (1987) A rapid in vitro assay for quantitating the invasive potential of tumor cells. Cancer Res 47:3239–3245
-
(1987)
Cancer Res
, vol.47
, pp. 3239-3245
-
-
Albini, A.1
Iwamoto, Y.2
Kleinman, H.K.3
-
22
-
-
33749044182
-
Risk-adapted craniospinal radiotherapy followed by high-dose chemotherapy and stem-cell rescue in children with newly diagnosed medulloblastoma (St Jude Medulloblastoma-96): long-term results from a prospective, multicentre trial
-
PID: 17012043
-
Gajjar A, Chintagumpala M, Ashley D, Kellie S, Kun LE, Merchant TE, Woo S, Wheeler G, Ahern V, Krasin MJ, Fouladi M, Broniscer A, Krance R, Hale GA, Stewart CF, Dauser R, Sanford RA, Fuller C, Lau C, Boyett JM, Wallace D, Gilbertson RJ (2006) Risk-adapted craniospinal radiotherapy followed by high-dose chemotherapy and stem-cell rescue in children with newly diagnosed medulloblastoma (St Jude Medulloblastoma-96): long-term results from a prospective, multicentre trial. Lancet Oncol 7:813–820
-
(2006)
Lancet Oncol
, vol.7
, pp. 813-820
-
-
Gajjar, A.1
Chintagumpala, M.2
Ashley, D.3
Kellie, S.4
Kun, L.E.5
Merchant, T.E.6
Woo, S.7
Wheeler, G.8
Ahern, V.9
Krasin, M.J.10
Fouladi, M.11
Broniscer, A.12
Krance, R.13
Hale, G.A.14
Stewart, C.F.15
Dauser, R.16
Sanford, R.A.17
Fuller, C.18
Lau, C.19
Boyett, J.M.20
Wallace, D.21
Gilbertson, R.J.22
more..
-
23
-
-
0034053069
-
Wnt signaling in oncogenesis and embryogenesis—a look outside the nucleus
-
Peifer M, Polakis P (2000) Wnt signaling in oncogenesis and embryogenesis—a look outside the nucleus. Science 2000:1606–1609
-
(2000)
Science
, vol.2000
, pp. 1606-1609
-
-
Peifer, M.1
Polakis, P.2
-
24
-
-
0033895709
-
Wnt signaling and cancer
-
COI: 1:CAS:528:DC%2BD3cXls1yqsbc%3D, PID: 10921899
-
Polakis P (2000) Wnt signaling and cancer. Genes Dev 14:1837–1851
-
(2000)
Genes Dev
, vol.14
, pp. 1837-1851
-
-
Polakis, P.1
-
25
-
-
33746808398
-
Wnt/beta-catenin signalling in development and disease
-
COI: 1:CAS:528:DC%2BD28Xht1WhtbbN, PID: 17081971
-
Clevers H (2006) Wnt/beta-catenin signalling in development and disease. Cell 127:469–480
-
(2006)
Cell
, vol.127
, pp. 469-480
-
-
Clevers, H.1
-
26
-
-
84871145562
-
β-catenin signalling in glioblastoma multiforme and glioma-initiating cells
-
PID: 22400111
-
Nager M, Bhardwaj D, Cantì C, Medina L, Nogués P, Herreros J (2012) β-catenin signalling in glioblastoma multiforme and glioma-initiating cells. Chemother Res Pract 2012:192362
-
(2012)
Chemother Res Pract
, vol.2012
, pp. 192362
-
-
Nager, M.1
Bhardwaj, D.2
Cantì, C.3
Medina, L.4
Nogués, P.5
Herreros, J.6
-
27
-
-
45749109850
-
c-Myc and beta-catenin cooperate with loss of p53 to generate multiple members of the primitive neuroectodermal tumor family in mice
-
COI: 1:CAS:528:DC%2BD1cXovV2ksLc%3D, PID: 18372915
-
Momota H, Shih AH, Edgar MA, Holland EC (2008) c-Myc and beta-catenin cooperate with loss of p53 to generate multiple members of the primitive neuroectodermal tumor family in mice. Oncogene 27:4392–4401
-
(2008)
Oncogene
, vol.27
, pp. 4392-4401
-
-
Momota, H.1
Shih, A.H.2
Edgar, M.A.3
Holland, E.C.4
-
28
-
-
84860378325
-
Global gene expression profiling confirms the molecular fidelity of primary tumor-based orthotopic xenograft mouse models of medulloblastoma
-
COI: 1:CAS:528:DC%2BC38Xhtl2hsLnO, PID: 22459127
-
Zhao X, Liu Z, Yu L, Zhang Y, Baxter P, Voicu H, Gurusiddappa S, Luan J, Su JM, Leung HC, Li XN (2012) Global gene expression profiling confirms the molecular fidelity of primary tumor-based orthotopic xenograft mouse models of medulloblastoma. Neuro Oncol 14:574–583
-
(2012)
Neuro Oncol
, vol.14
, pp. 574-583
-
-
Zhao, X.1
Liu, Z.2
Yu, L.3
Zhang, Y.4
Baxter, P.5
Voicu, H.6
Gurusiddappa, S.7
Luan, J.8
Su, J.M.9
Leung, H.C.10
Li, X.N.11
-
29
-
-
77956266718
-
A re-evaluation of the “oncogenic” nature of Wnt/beta-catenin signaling in melanoma and other cancers
-
COI: 1:CAS:528:DC%2BC3cXht1CjsLbP, PID: 20603725
-
Lucero OM, Dawson DW, Moon RT, Chien AJ (2010) A re-evaluation of the “oncogenic” nature of Wnt/beta-catenin signaling in melanoma and other cancers. Curr Oncol Rep 12:314–318
-
(2010)
Curr Oncol Rep
, vol.12
, pp. 314-318
-
-
Lucero, O.M.1
Dawson, D.W.2
Moon, R.T.3
Chien, A.J.4
-
30
-
-
84872923971
-
Constitutive activation of beta-catenin in neural progenitors results in disrupted proliferation and migration of neurons within the central nervous system
-
PID: 23237957
-
Pöschl J, Grammel D, Dorostkar MM, Batash R, Pöschl J, Schaffer PM (2013) Constitutive activation of beta-catenin in neural progenitors results in disrupted proliferation and migration of neurons within the central nervous system. Dev Biol 374:319–332
-
(2013)
Dev Biol
, vol.374
, pp. 319-332
-
-
Pöschl, J.1
Grammel, D.2
Dorostkar, M.M.3
Batash, R.4
Pöschl, J.5
Schaffer, P.M.6
|