Hypothalamic orexin prevents hepatic insulin resistance via daily bidirectional regulation of autonomic nervous system in mice

Diabetes

Volumn 64, Issue 2, 2015, Pages 459-470

  Tsuneki, Hiroshi ^a   Tokai, Emi ^a   Nakamura, Yuya ^a   Takahashi, Keisuke ^a   Fujita, Mikio ^a   Asaoka, Takehiro ^a   Kon, Kanta ^a   Anzawa, Yuuki ^a   Wada, Tsutomu ^a   Takasaki, Ichiro ^a   Kimura, Kumi ^b   Inoue, Hiroshi ^b   Yanagisawa, Masashi ^c,d   Sakurai, Takeshi ^e   Sasaoka, Toshiyasu ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

^b KANAZAWA UNIVERSITY   (Japan)

^c UNIVERSITY OF TSUKUBA   (Japan)

^d UNIVERSITY OF TEXAS AT DALLAS   (United States)

^e KANAZAWA UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; CORTICOSTERONE; FATTY ACID; GLUCOSE; GLUCOSE 6 PHOSPHATASE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INTERLEUKIN 1BETA; MESSENGER RNA; OREXIN; OREXIN A; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROTEIN KINASE B; STAT3 PROTEIN; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; ADRENALIN; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; GLUCOSE BLOOD LEVEL; LEPTIN RECEPTOR; NEUROPEPTIDE; OREXIN RECEPTOR; OREXINS; SIGNAL PEPTIDE;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTONOMIC NERVOUS SYSTEM; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; ENDOPLASMIC RETICULUM STRESS; ENERGY EXPENDITURE; FATTY ACID BLOOD LEVEL; FEEDING; GENE EXPRESSION; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; GLYCEMIC CONTROL; HYPOTHALAMUS; INSULIN RESISTANCE; INSULIN SENSITIVITY; MALE; MOUSE; NONHUMAN; OSCILLATION; PARASYMPATHETIC TONE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRIACYLGLYCEROL BLOOD LEVEL; VAGOTOMY; WAKEFULNESS; ANIMAL; C57BL MOUSE; CIRCADIAN RHYTHM; DRUG EFFECTS; GENETICS; LIVER; METABOLISM; SUICIDE TRANSGENE;

ANIMALS; AUTONOMIC NERVOUS SYSTEM; BLOOD GLUCOSE; CIRCADIAN RHYTHM; EPINEPHRINE; GENES, TRANSGENIC, SUICIDE; HYPOTHALAMUS; INSULIN RESISTANCE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIVER; MALE; MICE; MICE, INBRED C57BL; NEUROPEPTIDES; NEUROTRANSMITTER AGENTS; OREXIN RECEPTORS; RECEPTORS, LEPTIN;

EID: 84921934041     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db14-0695     Document Type: Article

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