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Volumn 65, Issue 1, 1999, Pages 14-22

Down regulation of the prepro-orexin gene expression in genetically obese mice

Author keywords

Hypocretin; Immunohistochemistry; In situ hybridization histochemistry; Neuropeptide Y; Obese; Orexin

Indexed keywords

NEUROPEPTIDE Y; OREXIN; PREPRO OREXIN; PROTEIN PRECURSOR; UNCLASSIFIED DRUG;

EID: 0033582606     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(98)00320-9     Document Type: Article
Times cited : (151)

References (36)
  • 1
    • 0021918223 scopus 로고
    • An arcuato-paraventricular and -dorsomedial hypothalamic neuropeptide Y-containing system which lacks noradrenaline in the rat
    • F.L. Bai, M. Yamano, Y. Shiotani, P.C. Emson, A.D. Smith, J.F. Powell, M. Toyama, An arcuato-paraventricular and -dorsomedial hypothalamic neuropeptide Y-containing system which lacks noradrenaline in the rat, Brain Res. 331 (1985) 172-175.
    • (1985) Brain Res. , vol.331 , pp. 172-175
    • Bai, F.L.1    Yamano, M.2    Shiotani, Y.3    Emson, P.C.4    Smith, A.D.5    Powell, J.F.6    Toyama, M.7
  • 2
    • 0027280380 scopus 로고
    • Tha lateral hypothalamic area revisited: Neuroanatomy, body weight regulation, neuroendocrinology and metabolism
    • L.L. Bermardis, L.L. Bellinger, Tha lateral hypothalamic area revisited: neuroanatomy, body weight regulation, neuroendocrinology and metabolism, Neurosci. Biobehav. Rev. 17 (1993) 141-193.
    • (1993) Neurosci. Biobehav. Rev. , vol.17 , pp. 141-193
    • Bermardis, L.L.1    Bellinger, L.L.2
  • 3
    • 0029759523 scopus 로고    scopus 로고
    • Tha lateral hypothalamic area revisited: Ingestive behavior
    • L.L. Bernardis, L.L. Bellinger, Tha lateral hypothalamic area revisited: ingestive behavior, Neurosci. Biobehav. Rev. 20 (1996) 189-287.
    • (1996) Neurosci. Biobehav. Rev. , vol.20 , pp. 189-287
    • Bernardis, L.L.1    Bellinger, L.L.2
  • 4
    • 0026022088 scopus 로고
    • Effects of intracerebroventricular injection of neuropeptide Y on energy metabolism
    • C.J. Billington, J.E. Briggs, M. Grace, A.S. Levine, Effects of intracerebroventricular injection of neuropeptide Y on energy metabolism, Am. J. Physiol. 260 (1991) R321-327.
    • (1991) Am. J. Physiol. , vol.260
    • Billington, C.J.1    Briggs, J.E.2    Grace, M.3    Levine, A.S.4
  • 6
    • 0030928715 scopus 로고    scopus 로고
    • Proopiomelanocortin neurons are direct targets for leptin in the hypothalamus
    • C.C. Cheung, D.K. Clifton, R.A. Steiner, Proopiomelanocortin neurons are direct targets for leptin in the hypothalamus, Endocrinology 138 (1997) 4489-4492.
    • (1997) Endocrinology , vol.138 , pp. 4489-4492
    • Cheung, C.C.1    Clifton, D.K.2    Steiner, R.A.3
  • 7
    • 0026072307 scopus 로고
    • Food deprivation and hypothalamic neuropeptide gene expression. Effects of strain background and the diabetes mutation
    • S.C. Chura Jr., A.W. Brown, J. Kim, K.L. Hennessey, R.L. Leibel, J. Hirsch, Food deprivation and hypothalamic neuropeptide gene expression. Effects of strain background and the diabetes mutation, Mol. Brain Res. 11 (1991) 291-299.
    • (1991) Mol. Brain Res. , vol.11 , pp. 291-299
    • Chura S.C., Jr.1    Brown, A.W.2    Kim, J.3    Hennessey, K.L.4    Leibel, R.L.5    Hirsch, J.6
  • 9
    • 0021248888 scopus 로고
    • Neoropeptide Y and human pancreatic polypeptide stimulate feeding behavior in rats
    • J.T. Clark, P.S. Kalra, W.R. Crowley, S.R. Kalra, Neoropeptide Y and human pancreatic polypeptide stimulate feeding behavior in rats, Endocrinology 115 (1984) 427-429.
    • (1984) Endocrinology , vol.115 , pp. 427-429
    • Clark, J.T.1    Kalra, P.S.2    Crowley, W.R.3    Kalra, S.R.4
  • 10
    • 0030914157 scopus 로고    scopus 로고
    • Stimulation of corticotropin-releasing hormone release by the obese (ob) gene product, leptine, from hypothalamic explants
    • A. Costa, A. Poma, E. Martignoni, G. Nappi, E. Ur, A. Grossman, Stimulation of corticotropin-releasing hormone release by the obese (ob) gene product, leptine, from hypothalamic explants, NeuroReport 8 (1997) 1131-1134.
    • (1997) NeuroReport , vol.8 , pp. 1131-1134
    • Costa, A.1    Poma, A.2    Martignoni, E.3    Nappi, G.4    Ur, E.5    Grossman, A.6
  • 12
    • 0029804743 scopus 로고    scopus 로고
    • Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y
    • J.C. Erickson, G. Hollopeter, R.D. Palmiter, Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y, Science 274 (1996) 1704-1707.
    • (1996) Science , vol.274 , pp. 1704-1707
    • Erickson, J.C.1    Hollopeter, G.2    Palmiter, R.D.3
  • 17
    • 0000659858 scopus 로고    scopus 로고
    • Leptin prevents fasting-induced suppression of prothyrotropin-releasing hormone messenger ribonucleic acid in neurons of the hypothalamic paraventricular nucleus
    • G. Legradi, C.H. Emerson, R.S. Ahima, J.S. Flier, R.M. Lechan, Leptin prevents fasting-induced suppression of prothyrotropin-releasing hormone messenger ribonucleic acid in neurons of the hypothalamic paraventricular nucleus, Endocrinology 138 (1997) 2569-2576.
    • (1997) Endocrinology , vol.138 , pp. 2569-2576
    • Legradi, G.1    Emerson, C.H.2    Ahima, R.S.3    Flier, J.S.4    Lechan, R.M.5
  • 18
    • 0025612094 scopus 로고
    • Localization of insulin receptor mRNA in rat brain by in situ hybridization
    • J.L. Marks, D. Porte Jr., W. Stahl, D.G. Baskin, Localization of insulin receptor mRNA in rat brain by in situ hybridization, Endocrinology 127 (1990) 3234-3236.
    • (1990) Endocrinology , vol.127 , pp. 3234-3236
    • Marks, J.L.1    Porte D., Jr.2    Stahl, W.3    Baskin, D.G.4
  • 21
    • 0000139058 scopus 로고
    • Input-output organization in the hypothalamus relating to food intake behavior
    • Marcel Dekker, New York
    • Y. Oomura, Input-output organization in the hypothalamus relating to food intake behavior, Handbook of the Hypothalamus, Vol. 2, Marcel Dekker, New York, 1980, pp. 557-620.
    • (1980) Handbook of the Hypothalamus , vol.2 , pp. 557-620
    • Oomura, Y.1
  • 22
    • 0019445983 scopus 로고
    • Insulin acting as a modulator of feeding through the hypothalamus
    • Y. Oomura, H. Kita, Insulin acting as a modulator of feeding through the hypothalamus, Diabetologia 20 (1981) 290-298.
    • (1981) Diabetologia , vol.20 , pp. 290-298
    • Oomura, Y.1    Kita, H.2
  • 23
    • 0016191102 scopus 로고
    • Glucose inhibition of the glucose-sensitive neuron in the rat lateral hypothalamus
    • Y. Oomura, H. Ooyama, M. Sugimori, T. Nakamura, Y. Yamada, Glucose inhibition of the glucose-sensitive neuron in the rat lateral hypothalamus, Nature 247 (1974) 284-286.
    • (1974) Nature , vol.247 , pp. 284-286
    • Oomura, Y.1    Ooyama, H.2    Sugimori, M.3    Nakamura, T.4    Yamada, Y.5
  • 24
    • 0026438979 scopus 로고
    • Regulation of insulin receptor substrate-1 in liver and muscle of animal models of insulin resistance
    • M.J.A. Saad, E. Araki, M. Mirapleix, P.L. Rothenberg, M.F. White, C.R. Kahn, Regulation of insulin receptor substrate-1 in liver and muscle of animal models of insulin resistance, J. Clin. Invest. 90 (1992) 1839-1949.
    • (1992) J. Clin. Invest. , vol.90 , pp. 1839-1949
    • Saad, M.J.A.1    Araki, E.2    Mirapleix, M.3    Rothenberg, P.L.4    White, M.F.5    Kahn, C.R.6
  • 30
    • 0025808045 scopus 로고
    • Insulin acts on hypothalamic glucose-facilitated neurons to induce hyperglycemia and hyperinsulinemia in the rat
    • L.R. Shian, M.T. Lin, Insulin acts on hypothalamic glucose-facilitated neurons to induce hyperglycemia and hyperinsulinemia in the rat, Experienta 47 (1991) 942-944.
    • (1991) Experienta , vol.47 , pp. 942-944
    • Shian, L.R.1    Lin, M.T.2
  • 31
    • 0029143608 scopus 로고
    • Insulin resistance is associated with abnormal dephosphorylation of a synthetic phosphopeptide corresponding to the major autophosphorylation sites of the insulin receptor
    • J. Sredy, D.R. Sawicki, B.R. Flam, D. Sullivan, Insulin resistance is associated with abnormal dephosphorylation of a synthetic phosphopeptide corresponding to the major autophosphorylation sites of the insulin receptor, Metabolism 44 (1995) 1074-1081.
    • (1995) Metabolism , vol.44 , pp. 1074-1081
    • Sredy, J.1    Sawicki, D.R.2    Flam, B.R.3    Sullivan, D.4
  • 33
    • 0030729210 scopus 로고    scopus 로고
    • Regulation of hypothalamic proopiomelanocortin mRNA by leptin in ob/ob mice
    • J.E. Thornton, C.C. Cheung, D.K. Clifton, R.A. Steiner, Regulation of hypothalamic proopiomelanocortin mRNA by leptin in ob/ob mice, Endocrinology 138 (1997) 5063-5066.
    • (1997) Endocrinology , vol.138 , pp. 5063-5066
    • Thornton, J.E.1    Cheung, C.C.2    Clifton, D.K.3    Steiner, R.A.4
  • 34
    • 0027319108 scopus 로고
    • Increased neuropeptide-Y messenger ribonucleic acid (mRNA) and decreased neurotensin mRNA in the hypothalamus of the obese (ob/ob) mouse
    • J.P.H. Wilding, S.G. Gilbey, C.J. Bailey, R.A.L. Batt, G. Willians, M.A. Ghatei, S.R. Bloom, Increased neuropeptide-Y messenger ribonucleic acid (mRNA) and decreased neurotensin mRNA in the hypothalamus of the obese (ob/ob) mouse, Endocrinology 132 (1993) 1939-1944.
    • (1993) Endocrinology , vol.132 , pp. 1939-1944
    • Wilding, J.P.H.1    Gilbey, S.G.2    Bailey, C.J.3    Batt, R.A.L.4    Willians, G.5    Ghatei, M.A.6    Bloom, S.R.7
  • 36
    • 0027362079 scopus 로고
    • Chronic intracerebroventricular neuropeptide-Y administration to normal rats mimics hormonal and metabolic changes of obesity
    • N. Zarjevski, I. Cusin, R. Vettor, F. Rohner-Jeanrenaud, B. Jeanrenaud, Chronic intracerebroventricular neuropeptide-Y administration to normal rats mimics hormonal and metabolic changes of obesity, Endocrinology 133 (1993) 1753-1758.
    • (1993) Endocrinology , vol.133 , pp. 1753-1758
    • Zarjevski, N.1    Cusin, I.2    Vettor, R.3    Rohner-Jeanrenaud, F.4    Jeanrenaud, B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.